Click here to switch to the map view.

The map label for this gene is engD [H]

Identifier: 213692557

GI number: 213692557

Start: 1842948

End: 1844126

Strand: Reverse

Name: engD [H]

Synonym: Blon_1689

Alternate gene names: 213692557

Gene position: 1844126-1842948 (Counterclockwise)

Preceding gene: 213692558

Following gene: 213692554

Centisome position: 65.1

GC content: 60.98

Gene sequence:

>1179_bases
ATGCTCGGAGGCCTTTGCATATGGCCGGTTCACCACATGCAGGTTCAAGGTGTCCAGCTTCTCCCTAGACTTGGAATCAT
GTCTCTTACTATCGGAATCGTCGGACTGCCCAACGTCGGCAAGTCCACCATGTTCAACGCACTGACCCGCAACAACGTGC
TGGCTGAAAACTACCCGTTCGCCACCATCGAACCGAACACTGGCATCGTACCGTTGCCGGACAAGCGCCTGCCGGTACTG
GCCAAGCTGGTCCACACCGAAAAGGTCGTGCCCGCCACGGTGACCTTCGTAGACATCGCCGGCATCGTCAAGGGCGCCTC
CGAGGGCGAAGGCCTGGGCAACAAGTTCCTGGCCAACATCCGCGAGGCGGACGCGATTTGCGAGGTCGTGCGCGCCTTCG
AGGACGACGACATCGTCCACGTCAACGGCAAGGTGGATCCGGCCGACGACATCGACACCATCAACACCGAGCTGATCCTC
GCCGACCTGCAGACCATCGAAAACGCGCTGCCCAAGCTGGAGAAGGATCTGCGCGGCAAGAAGATCGAGCCGGCCTACAT
GGACGCTGTCAAGCAGGCAAAGACCATCCTTGAAGCCGGCGAGACGCTCGACAAGGCCGCACGCGAAGGCCGCTTCGACA
AGGATTCCGTCTACGACCTGCATCTGATGACCGCCAAGCCGTTCATCTACGTGTTCAACGTGGACGACAACGAGCTGGCC
AACAAGAACCTGCAGGCAAAGCTCGCCGCATCCGTGGCCCCGGCTCCGGCCGTGTTCCTCAACGCTCAGTTCGAGGCAGA
CCTGACCGAGCTCGACGAGGCGGACGCCCGCGAAATGCTGGCCGACGCTGGCTTGAGTGAGTCCGGTCTTGACCAGTTGG
CCCGCGTCGGCTTCGACATCCTCGGCTTGCAGACCTTCCTGACCGCAGGCGTCAAGGAAGTGCGCGCTTGGCAGATCCAC
AAGGGCTGGACCGCCCCGCAGGCCGCCGGCGTGATTCACACCGACTTCGAAAAGGGCTTCATCAAGGCTGACATCGTCTC
CTACGACGATTTCGTGGCCGCCGACGGCTCCATGGCCAAGATCAAGGAGGAAGGCAAGCTCCGTCAGGAAGGCCGCGACT
ACGTCATGGCCGACGGAGATATTGTGGAGTTCAAGTTCTCCCCAACGTCTAAGAAGTGA

Upstream 100 bases:

>100_bases
TTCCGCGGCTCGGTCATCGACGCCGTAGACGCCATCGTCGGCTGACTGCCAATCAGAGTTCGCGTATATTCGCATATCAC
AGTCAAAGCCTTCGAACCGT

Downstream 100 bases:

>100_bases
CCGTTTGGTAGTGCTGAAAATCTGGGAATTCTAGGGTGTGTTTACATTATCTAGGTTTTGTGTGATATCTGGCGTACACA
TACGATAATTATCACACAAA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MLGGLCIWPVHHMQVQGVQLLPRLGIMSLTIGIVGLPNVGKSTMFNALTRNNVLAENYPFATIEPNTGIVPLPDKRLPVL
AKLVHTEKVVPATVTFVDIAGIVKGASEGEGLGNKFLANIREADAICEVVRAFEDDDIVHVNGKVDPADDIDTINTELIL
ADLQTIENALPKLEKDLRGKKIEPAYMDAVKQAKTILEAGETLDKAAREGRFDKDSVYDLHLMTAKPFIYVFNVDDNELA
NKNLQAKLAASVAPAPAVFLNAQFEADLTELDEADAREMLADAGLSESGLDQLARVGFDILGLQTFLTAGVKEVRAWQIH
KGWTAPQAAGVIHTDFEKGFIKADIVSYDDFVAADGSMAKIKEEGKLRQEGRDYVMADGDIVEFKFSPTSKK

Sequences:

>Translated_392_residues
MLGGLCIWPVHHMQVQGVQLLPRLGIMSLTIGIVGLPNVGKSTMFNALTRNNVLAENYPFATIEPNTGIVPLPDKRLPVL
AKLVHTEKVVPATVTFVDIAGIVKGASEGEGLGNKFLANIREADAICEVVRAFEDDDIVHVNGKVDPADDIDTINTELIL
ADLQTIENALPKLEKDLRGKKIEPAYMDAVKQAKTILEAGETLDKAAREGRFDKDSVYDLHLMTAKPFIYVFNVDDNELA
NKNLQAKLAASVAPAPAVFLNAQFEADLTELDEADAREMLADAGLSESGLDQLARVGFDILGLQTFLTAGVKEVRAWQIH
KGWTAPQAAGVIHTDFEKGFIKADIVSYDDFVAADGSMAKIKEEGKLRQEGRDYVMADGDIVEFKFSPTSKK
>Mature_392_residues
MLGGLCIWPVHHMQVQGVQLLPRLGIMSLTIGIVGLPNVGKSTMFNALTRNNVLAENYPFATIEPNTGIVPLPDKRLPVL
AKLVHTEKVVPATVTFVDIAGIVKGASEGEGLGNKFLANIREADAICEVVRAFEDDDIVHVNGKVDPADDIDTINTELIL
ADLQTIENALPKLEKDLRGKKIEPAYMDAVKQAKTILEAGETLDKAAREGRFDKDSVYDLHLMTAKPFIYVFNVDDNELA
NKNLQAKLAASVAPAPAVFLNAQFEADLTELDEADAREMLADAGLSESGLDQLARVGFDILGLQTFLTAGVKEVRAWQIH
KGWTAPQAAGVIHTDFEKGFIKADIVSYDDFVAADGSMAKIKEEGKLRQEGRDYVMADGDIVEFKFSPTSKK

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=389, Percent_Identity=42.9305912596401, Blast_Score=281, Evalue=9e-76,
Organism=Homo sapiens, GI58761502, Length=232, Percent_Identity=37.5, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI1787454, Length=372, Percent_Identity=50, Blast_Score=348, Evalue=2e-97,
Organism=Escherichia coli, GI1789574, Length=196, Percent_Identity=29.0816326530612, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=382, Percent_Identity=40.8376963350785, Blast_Score=265, Evalue=4e-71,
Organism=Saccharomyces cerevisiae, GI6319499, Length=384, Percent_Identity=39.0625, Blast_Score=222, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6321773, Length=385, Percent_Identity=35.5844155844156, Blast_Score=213, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6321649, Length=142, Percent_Identity=37.3239436619718, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24640873, Length=394, Percent_Identity=43.4010152284264, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI24640877, Length=394, Percent_Identity=43.4010152284264, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI24640875, Length=394, Percent_Identity=43.4010152284264, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI24640879, Length=344, Percent_Identity=41.8604651162791, Blast_Score=226, Evalue=2e-59,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 42669; Mature: 42669

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGGLCIWPVHHMQVQGVQLLPRLGIMSLTIGIVGLPNVGKSTMFNALTRNNVLAENYPF
CCCCEEECCHHHHEECCHHHHHHHCHHHHHHHEEECCCCCHHHHHHHHHHCCEEECCCCE
ATIEPNTGIVPLPDKRLPVLAKLVHTEKVVPATVTFVDIAGIVKGASEGEGLGNKFLANI
EEECCCCCEEECCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCCCCCCCHHHHHHH
READAICEVVRAFEDDDIVHVNGKVDPADDIDTINTELILADLQTIENALPKLEKDLRGK
HHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
KIEPAYMDAVKQAKTILEAGETLDKAAREGRFDKDSVYDLHLMTAKPFIYVFNVDDNELA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEECCCHHHH
NKNLQAKLAASVAPAPAVFLNAQFEADLTELDEADAREMLADAGLSESGLDQLARVGFDI
CCCCHHHHHHHCCCCCEEEEECCCCCCHHHHCHHHHHHHHHHCCCCHHHHHHHHHHCHHH
LGLQTFLTAGVKEVRAWQIHKGWTAPQAAGVIHTDFEKGFIKADIVSYDDFVAADGSMAK
HHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEECCCCCCEEEEEECCCCCEECCCCHHH
IKEEGKLRQEGRDYVMADGDIVEFKFSPTSKK
HHHHCCHHHCCCCEEEECCCEEEEEECCCCCC
>Mature Secondary Structure
MLGGLCIWPVHHMQVQGVQLLPRLGIMSLTIGIVGLPNVGKSTMFNALTRNNVLAENYPF
CCCCEEECCHHHHEECCHHHHHHHCHHHHHHHEEECCCCCHHHHHHHHHHCCEEECCCCE
ATIEPNTGIVPLPDKRLPVLAKLVHTEKVVPATVTFVDIAGIVKGASEGEGLGNKFLANI
EEECCCCCEEECCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCCCCCCCHHHHHHH
READAICEVVRAFEDDDIVHVNGKVDPADDIDTINTELILADLQTIENALPKLEKDLRGK
HHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
KIEPAYMDAVKQAKTILEAGETLDKAAREGRFDKDSVYDLHLMTAKPFIYVFNVDDNELA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEECCCHHHH
NKNLQAKLAASVAPAPAVFLNAQFEADLTELDEADAREMLADAGLSESGLDQLARVGFDI
CCCCHHHHHHHCCCCCEEEEECCCCCCHHHHCHHHHHHHHHHCCCCHHHHHHHHHHCHHH
LGLQTFLTAGVKEVRAWQIHKGWTAPQAAGVIHTDFEKGFIKADIVSYDDFVAADGSMAK
HHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEECCCCCCEEEEEECCCCCEECCCCHHH
IKEEGKLRQEGRDYVMADGDIVEFKFSPTSKK
HHHHCCHHHCCCCEEEECCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]