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The map label for this gene is nadB [H]

Identifier: 213691803

GI number: 213691803

Start: 1075116

End: 1076747

Strand: Direct

Name: nadB [H]

Synonym: Blon_0911

Alternate gene names: 213691803

Gene position: 1075116-1076747 (Clockwise)

Preceding gene: 213691802

Following gene: 213691804

Centisome position: 37.95

GC content: 68.08

Gene sequence:

>1632_bases
ATGAGCAACACTGAAATCGTCGTCGTGGGCGCAGGCGTCGCCGGACTGTCCGCGGCACTGGCCGTGGCCGGCACCGGACA
CGACGTGACCTTGGTAACCAAGGCCGAACTGGTGGAATCGAACACCTATCATGCGCAGGGCGGCATCGCTGCGGCCATCT
TCTCCGACGACGACCCGAAGCTGCACGCCGCCGACACCATGGCCGCGGGCCACGGCCTGTGCGACCCGAAGGCCGTGGAC
ATCCTCACCCGTGAGGGTGCGGAGCGCGTCCGCGAGTTCGCCGCGGCCGGCGTCCACTTCGACCGCGACGCGCAGGGACA
CATGCTGCGCGGCCTGGAAGCGGCTCATTCGCGCGCCCGCGTGGTGCATGCCGGGGGAGACGCCACCGGCAAAGTGCTCG
AACTGGACGTCTCCGCCATGGTGCGCAAGAACCCGCGCATCCACATCATCGAGAACGCATTCCTCAAAGACCTCATCGTG
CGGGACGGCCACATCGCCGGCGTCCGCCTGCTGATCGACGGGCAGGACAAGGATCTGTCCGCCGACCGGGTGATCTTGGC
CGCCGGTGGAGCAGGCCGTATGTACCCGTACACCACCAATCCGCCGGTCGCCACCGCGGACGGCCTCGCCGCCGCATGGC
GTGCGGGCGCCCAGGTCGCCGATCTGGAGTTCTACCAGTTCCATCCCACCGCCATGGCCGTGGGCGAGCACTTCCTCGTC
TCCGAAGCCGTGCGCGGCGAAGGCGCGGTGCTGCTGGACGAACACGGCCACCGGTACATGAGGGACATCGATCCGCGCGC
CGAACTCGCACCGCGCGACGTCGTGGCCCGCGAGAACTTCCGCGTGATGCAGGCGCAAGGCGGCAAGCCCGTGATGCTCG
ACGTGTCGCCGATGACCCGCGAGAACCCCGACCTGGCCAGCTTCCTGGCCCACCGATTCCCGACCATCGACGCCTATACG
CGTTCGCTTGGCTTCGACTGGAGCAAGGAGCCGATCCCGGTGGCGCCCGCCGCGCACTACTACATGGGAGGCATTCGCAC
CGATCTGAACGCCCGGACCTCCATCCCCGGCCTGTACGCGGCCGGCGAATGCGCCCGCACCGGTGTCATGGGCTCCAACC
GCCTTGCCTCCAACTCGCTGCTCGAAGGACTTGTCTACGGACGCCGCGCCGGTCTTGCCGCCGTCGCGGACGGTGACGAC
GCGGTCTGGGCACCCGAACCGTTCCTGAACTCCGCCACCGGTGCCGTGTTCGACCATGCGCCGATCGCGCTGGCCGCTCC
TGCCGCTACGGCTGCTGCTGACGATACCGCCGCCGACAAGGTCTGGGACCGTACCCGCATCCAGAACACCATGTGGCATG
GCGTCGGCGTGCTGCGCGACGAGGCCGGACTGAAAACCGCCATCGCCGAACTCGGCCAAGGCCTCGCCGCCGCAAACGCC
CAGGCTGATGTAAACGCCGATGGTGCTGCAAGCAGCGTTGAGGCTTTGGAGAACCGCAACATGCTCACCGTAGGCTATGT
GGCCGCCATCGCCGCGCTCGCCCGCACCGAGTCGAGAGGCGCCCACGCCCGCACCGACTACAGCGAGCCAGTCGACAACT
GGGCCCACTCCGTCGCCTACATCAAGGACTAA

Upstream 100 bases:

>100_bases
TCACCCGTGACATGCTTCTAGCTCCCCCTCCCTGAGGGGAGCTGTCACCGTAGGTGACTGAGGGGGAGCGGATGACGCAA
AAACAGAGGAAAGCAACACA

Downstream 100 bases:

>100_bases
CCCATGCTCACATCACACATCATCCGCGTCGCCGTCGAAGCGGCGCTCGCCGAAGACGCGCCCTACGGCGACATCACCTG
CGAGACCACCATCCCCGCGG

Product: L-aspartate oxidase

Products: NA

Alternate protein names: LASPO; Quinolinate synthase B [H]

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MSNTEIVVVGAGVAGLSAALAVAGTGHDVTLVTKAELVESNTYHAQGGIAAAIFSDDDPKLHAADTMAAGHGLCDPKAVD
ILTREGAERVREFAAAGVHFDRDAQGHMLRGLEAAHSRARVVHAGGDATGKVLELDVSAMVRKNPRIHIIENAFLKDLIV
RDGHIAGVRLLIDGQDKDLSADRVILAAGGAGRMYPYTTNPPVATADGLAAAWRAGAQVADLEFYQFHPTAMAVGEHFLV
SEAVRGEGAVLLDEHGHRYMRDIDPRAELAPRDVVARENFRVMQAQGGKPVMLDVSPMTRENPDLASFLAHRFPTIDAYT
RSLGFDWSKEPIPVAPAAHYYMGGIRTDLNARTSIPGLYAAGECARTGVMGSNRLASNSLLEGLVYGRRAGLAAVADGDD
AVWAPEPFLNSATGAVFDHAPIALAAPAATAAADDTAADKVWDRTRIQNTMWHGVGVLRDEAGLKTAIAELGQGLAAANA
QADVNADGAASSVEALENRNMLTVGYVAAIAALARTESRGAHARTDYSEPVDNWAHSVAYIKD

Sequences:

>Translated_543_residues
MSNTEIVVVGAGVAGLSAALAVAGTGHDVTLVTKAELVESNTYHAQGGIAAAIFSDDDPKLHAADTMAAGHGLCDPKAVD
ILTREGAERVREFAAAGVHFDRDAQGHMLRGLEAAHSRARVVHAGGDATGKVLELDVSAMVRKNPRIHIIENAFLKDLIV
RDGHIAGVRLLIDGQDKDLSADRVILAAGGAGRMYPYTTNPPVATADGLAAAWRAGAQVADLEFYQFHPTAMAVGEHFLV
SEAVRGEGAVLLDEHGHRYMRDIDPRAELAPRDVVARENFRVMQAQGGKPVMLDVSPMTRENPDLASFLAHRFPTIDAYT
RSLGFDWSKEPIPVAPAAHYYMGGIRTDLNARTSIPGLYAAGECARTGVMGSNRLASNSLLEGLVYGRRAGLAAVADGDD
AVWAPEPFLNSATGAVFDHAPIALAAPAATAAADDTAADKVWDRTRIQNTMWHGVGVLRDEAGLKTAIAELGQGLAAANA
QADVNADGAASSVEALENRNMLTVGYVAAIAALARTESRGAHARTDYSEPVDNWAHSVAYIKD
>Mature_542_residues
SNTEIVVVGAGVAGLSAALAVAGTGHDVTLVTKAELVESNTYHAQGGIAAAIFSDDDPKLHAADTMAAGHGLCDPKAVDI
LTREGAERVREFAAAGVHFDRDAQGHMLRGLEAAHSRARVVHAGGDATGKVLELDVSAMVRKNPRIHIIENAFLKDLIVR
DGHIAGVRLLIDGQDKDLSADRVILAAGGAGRMYPYTTNPPVATADGLAAAWRAGAQVADLEFYQFHPTAMAVGEHFLVS
EAVRGEGAVLLDEHGHRYMRDIDPRAELAPRDVVARENFRVMQAQGGKPVMLDVSPMTRENPDLASFLAHRFPTIDAYTR
SLGFDWSKEPIPVAPAAHYYMGGIRTDLNARTSIPGLYAAGECARTGVMGSNRLASNSLLEGLVYGRRAGLAAVADGDDA
VWAPEPFLNSATGAVFDHAPIALAAPAATAAADDTAADKVWDRTRIQNTMWHGVGVLRDEAGLKTAIAELGQGLAAANAQ
ADVNADGAASSVEALENRNMLTVGYVAAIAALARTESRGAHARTDYSEPVDNWAHSVAYIKD

Specific function: Catalyzes the oxidation of L-aspartate to iminoaspartate [H]

COG id: COG0029

COG function: function code H; Aspartate oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=541, Percent_Identity=30.8687615526802, Blast_Score=195, Evalue=7e-50,
Organism=Escherichia coli, GI1788928, Length=563, Percent_Identity=36.5896980461812, Blast_Score=299, Evalue=3e-82,
Organism=Escherichia coli, GI1786942, Length=579, Percent_Identity=31.7789291882556, Blast_Score=212, Evalue=5e-56,
Organism=Escherichia coli, GI1790597, Length=545, Percent_Identity=30.0917431192661, Blast_Score=211, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17505833, Length=542, Percent_Identity=31.9188191881919, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17550100, Length=544, Percent_Identity=31.6176470588235, Blast_Score=198, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI71986328, Length=467, Percent_Identity=27.8372591006424, Blast_Score=113, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6322416, Length=574, Percent_Identity=33.2752613240418, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6322701, Length=572, Percent_Identity=33.2167832167832, Blast_Score=198, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6320788, Length=476, Percent_Identity=25.4201680672269, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322511, Length=470, Percent_Identity=26.5957446808511, Blast_Score=90, Evalue=9e-19,
Organism=Drosophila melanogaster, GI17137288, Length=557, Percent_Identity=34.1113105924596, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24655642, Length=557, Percent_Identity=34.1113105924596, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24655647, Length=557, Percent_Identity=34.1113105924596, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24663005, Length=557, Percent_Identity=32.6750448833034, Blast_Score=196, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR005288 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.4.3.16 [H]

Molecular weight: Translated: 57260; Mature: 57129

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTEIVVVGAGVAGLSAALAVAGTGHDVTLVTKAELVESNTYHAQGGIAAAIFSDDDPK
CCCCEEEEEECCHHHHHHHHEEECCCCCEEEEEHHHHHCCCCEECCCCEEEEEECCCCCC
LHAADTMAAGHGLCDPKAVDILTREGAERVREFAAAGVHFDRDAQGHMLRGLEAAHSRAR
EEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEE
VVHAGGDATGKVLELDVSAMVRKNPRIHIIENAFLKDLIVRDGHIAGVRLLIDGQDKDLS
EEECCCCCCCCEEEEEHHHHHHCCCCEEEECHHHHHHHHHCCCCEEEEEEEEECCCCCCC
ADRVILAAGGAGRMYPYTTNPPVATADGLAAAWRAGAQVADLEFYQFHPTAMAVGEHFLV
CCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEEEECCHHHHHCCHHHH
SEAVRGEGAVLLDEHGHRYMRDIDPRAELAPRDVVARENFRVMQAQGGKPVMLDVSPMTR
HHHHCCCCEEEECCCCCHHHHCCCCCHHCCCHHHHHCCCEEEEECCCCCEEEEECCCCCC
ENPDLASFLAHRFPTIDAYTRSLGFDWSKEPIPVAPAAHYYMGGIRTDLNARTSIPGLYA
CCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHCCEEECCCCCCCCCCCEE
AGECARTGVMGSNRLASNSLLEGLVYGRRAGLAAVADGDDAVWAPEPFLNSATGAVFDHA
CCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEECCCCCCCCCCCCEECCC
PIALAAPAATAAADDTAADKVWDRTRIQNTMWHGVGVLRDEAGLKTAIAELGQGLAAANA
CEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCCCHHHCCC
QADVNADGAASSVEALENRNMLTVGYVAAIAALARTESRGAHARTDYSEPVDNWAHSVAY
CCCCCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCEEE
IKD
ECC
>Mature Secondary Structure 
SNTEIVVVGAGVAGLSAALAVAGTGHDVTLVTKAELVESNTYHAQGGIAAAIFSDDDPK
CCCEEEEEECCHHHHHHHHEEECCCCCEEEEEHHHHHCCCCEECCCCEEEEEECCCCCC
LHAADTMAAGHGLCDPKAVDILTREGAERVREFAAAGVHFDRDAQGHMLRGLEAAHSRAR
EEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEE
VVHAGGDATGKVLELDVSAMVRKNPRIHIIENAFLKDLIVRDGHIAGVRLLIDGQDKDLS
EEECCCCCCCCEEEEEHHHHHHCCCCEEEECHHHHHHHHHCCCCEEEEEEEEECCCCCCC
ADRVILAAGGAGRMYPYTTNPPVATADGLAAAWRAGAQVADLEFYQFHPTAMAVGEHFLV
CCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEEEECCHHHHHCCHHHH
SEAVRGEGAVLLDEHGHRYMRDIDPRAELAPRDVVARENFRVMQAQGGKPVMLDVSPMTR
HHHHCCCCEEEECCCCCHHHHCCCCCHHCCCHHHHHCCCEEEEECCCCCEEEEECCCCCC
ENPDLASFLAHRFPTIDAYTRSLGFDWSKEPIPVAPAAHYYMGGIRTDLNARTSIPGLYA
CCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHCCEEECCCCCCCCCCCEE
AGECARTGVMGSNRLASNSLLEGLVYGRRAGLAAVADGDDAVWAPEPFLNSATGAVFDHA
CCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEECCCCCCCCCCCCEECCC
PIALAAPAATAAADDTAADKVWDRTRIQNTMWHGVGVLRDEAGLKTAIAELGQGLAAANA
CEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCCCHHHCCC
QADVNADGAASSVEALENRNMLTVGYVAAIAALARTESRGAHARTDYSEPVDNWAHSVAY
CCCCCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCEEE
IKD
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]