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The map label for this gene is nadA [H]

Identifier: 213691802

GI number: 213691802

Start: 1073745

End: 1075025

Strand: Direct

Name: nadA [H]

Synonym: Blon_0910

Alternate gene names: 213691802

Gene position: 1073745-1075025 (Clockwise)

Preceding gene: 213691801

Following gene: 213691803

Centisome position: 37.9

GC content: 64.87

Gene sequence:

>1281_bases
ATGACCGCACTATCCACTGCGCCGTCCGTTGACGAGATCATCGCCAAGCTGGGCGCGCAAAGCACCTGCGATGCAGGACT
GACCCAGGACCCATGGCACTTCGACACCACCACACCCAGCTACGGTCCCGGTGCCTCGATGCTCGACCGTCTGCCCGCCA
ACGCGCCGCGTCAGCAGGTGCTGCCGGACGAATACCGCAAGGCCTCCGACGAGGAGCTGCAGCAGCGCATCACCGACGCC
AAGCAGCGTCTTGGCTCCAAACTGTTGATTCTGGGCCACTTCTACCAGCGTGACGAGATCATCAAGCACGCCGATTTCGT
GGGCGACTCCTTCCAGCTGGCCAAGAACGCCACCGAACGCCCGGACGCCGACCACATCGTGTTCTGCGGCGTGCACTTCA
TGGCCGAAACCGCCGACATCCTCTCCACGCCCGAACAGAGCGTGACCCTGCCCAACCTGTCCGCCGGCTGCTCGATGGCC
GATATGGCCAACATCGACCAGGTCCAGGAATGCTGGGACCAGCTCGGCGAGATCTGCGGCACCCAGCCGGACTCCGATGG
CTTGCAGCAGATCATCCCGGTCACCTACATGAACTCATCCGCCGCGCTGAAGGCGTTCTGCGGACGCAACGGCGGCATCG
TATGCACCTCGTCCAATGCGCACGCCGTGCTGGAATGGGCGTTCGCCCGCGGCAAGCGCGTGCTGTTCTTCCCGGACCAG
CATCTGGGCCGCAATACCGCCCGCGCGATGGGCATTCCGCTGAACGAGATGCCGCTGTGGGATCCGTTCAAGGCACAGGG
CGGCGCCGCCGATCCGGCCGACTACGCCCGCGCCAAGATGATTCTGTGGAAGGGCTTCTGCTCTGTGCACCAGCGCTTCA
CCGTCGAACAGGTCGAACGCGCCCGCAAGGCATACCCGGGCGTCAAGGTGATCGTGCACCCCGAGTGCTCGATGCAGGTG
GTCGACGCCGCCGACGGCACTGGCTCCACCGCGTACATCGTCAAGGAGATTGCCAACGCACCCGCCGGATCCGCCATCGC
CGTGGGCACCGAAATCAACCTGGTGAACCGTCTGGCCGCGCAGTACCCGGACAAGACCGTGTTCTGCCTGGACCCCGTGG
TCTGCCCCTGCTCCACGATGTACCGCATCCACCCGGCTTACCTGGCTTGGGCTTTGGAGAACCTCGAAGCCGGCAACGTG
GTCAATCGCATCACCGTGGACGAAGACACCGCCCGCGAAGCCAAGGTGGCGCTGGAGCGCATGCTGCGCGTTCACCCGTG
A

Upstream 100 bases:

>100_bases
AAGACGCTCTCGACGCGCTGATCCCATCCGCGCGCATCTGATTTTTCCCGCCGACCCGCTTCGGGCCGGCATCACAGACG
TATATAGGAAAGGAACCGCT

Downstream 100 bases:

>100_bases
CATGCTTCTAGCTCCCCCTCCCTGAGGGGAGCTGTCACCGTAGGTGACTGAGGGGGAGCGGATGACGCAAAAACAGAGGA
AAGCAACACAATGAGCAACA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MTALSTAPSVDEIIAKLGAQSTCDAGLTQDPWHFDTTTPSYGPGASMLDRLPANAPRQQVLPDEYRKASDEELQQRITDA
KQRLGSKLLILGHFYQRDEIIKHADFVGDSFQLAKNATERPDADHIVFCGVHFMAETADILSTPEQSVTLPNLSAGCSMA
DMANIDQVQECWDQLGEICGTQPDSDGLQQIIPVTYMNSSAALKAFCGRNGGIVCTSSNAHAVLEWAFARGKRVLFFPDQ
HLGRNTARAMGIPLNEMPLWDPFKAQGGAADPADYARAKMILWKGFCSVHQRFTVEQVERARKAYPGVKVIVHPECSMQV
VDAADGTGSTAYIVKEIANAPAGSAIAVGTEINLVNRLAAQYPDKTVFCLDPVVCPCSTMYRIHPAYLAWALENLEAGNV
VNRITVDEDTAREAKVALERMLRVHP

Sequences:

>Translated_426_residues
MTALSTAPSVDEIIAKLGAQSTCDAGLTQDPWHFDTTTPSYGPGASMLDRLPANAPRQQVLPDEYRKASDEELQQRITDA
KQRLGSKLLILGHFYQRDEIIKHADFVGDSFQLAKNATERPDADHIVFCGVHFMAETADILSTPEQSVTLPNLSAGCSMA
DMANIDQVQECWDQLGEICGTQPDSDGLQQIIPVTYMNSSAALKAFCGRNGGIVCTSSNAHAVLEWAFARGKRVLFFPDQ
HLGRNTARAMGIPLNEMPLWDPFKAQGGAADPADYARAKMILWKGFCSVHQRFTVEQVERARKAYPGVKVIVHPECSMQV
VDAADGTGSTAYIVKEIANAPAGSAIAVGTEINLVNRLAAQYPDKTVFCLDPVVCPCSTMYRIHPAYLAWALENLEAGNV
VNRITVDEDTAREAKVALERMLRVHP
>Mature_425_residues
TALSTAPSVDEIIAKLGAQSTCDAGLTQDPWHFDTTTPSYGPGASMLDRLPANAPRQQVLPDEYRKASDEELQQRITDAK
QRLGSKLLILGHFYQRDEIIKHADFVGDSFQLAKNATERPDADHIVFCGVHFMAETADILSTPEQSVTLPNLSAGCSMAD
MANIDQVQECWDQLGEICGTQPDSDGLQQIIPVTYMNSSAALKAFCGRNGGIVCTSSNAHAVLEWAFARGKRVLFFPDQH
LGRNTARAMGIPLNEMPLWDPFKAQGGAADPADYARAKMILWKGFCSVHQRFTVEQVERARKAYPGVKVIVHPECSMQVV
DAADGTGSTAYIVKEIANAPAGSAIAVGTEINLVNRLAAQYPDKTVFCLDPVVCPCSTMYRIHPAYLAWALENLEAGNVV
NRITVDEDTAREAKVALERMLRVHP

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=348, Percent_Identity=28.1609195402299, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 46506; Mature: 46375

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALSTAPSVDEIIAKLGAQSTCDAGLTQDPWHFDTTTPSYGPGASMLDRLPANAPRQQV
CCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHC
LPDEYRKASDEELQQRITDAKQRLGSKLLILGHFYQRDEIIKHADFVGDSFQLAKNATER
CCHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCHHHHHHCCCCC
PDADHIVFCGVHFMAETADILSTPEQSVTLPNLSAGCSMADMANIDQVQECWDQLGEICG
CCCCEEEEEHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHCCHHHHHHHHHHHHHHHC
TQPDSDGLQQIIPVTYMNSSAALKAFCGRNGGIVCTSSNAHAVLEWAFARGKRVLFFPDQ
CCCCCCHHHHHCCEEEECCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHCCCEEEECCCH
HLGRNTARAMGIPLNEMPLWDPFKAQGGAADPADYARAKMILWKGFCSVHQRFTVEQVER
HCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ARKAYPGVKVIVHPECSMQVVDAADGTGSTAYIVKEIANAPAGSAIAVGTEINLVNRLAA
HHHHCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHH
QYPDKTVFCLDPVVCPCSTMYRIHPAYLAWALENLEAGNVVNRITVDEDTAREAKVALER
HCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHH
MLRVHP
HHHCCC
>Mature Secondary Structure 
TALSTAPSVDEIIAKLGAQSTCDAGLTQDPWHFDTTTPSYGPGASMLDRLPANAPRQQV
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHC
LPDEYRKASDEELQQRITDAKQRLGSKLLILGHFYQRDEIIKHADFVGDSFQLAKNATER
CCHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCHHHHHHCCCCC
PDADHIVFCGVHFMAETADILSTPEQSVTLPNLSAGCSMADMANIDQVQECWDQLGEICG
CCCCEEEEEHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHCCHHHHHHHHHHHHHHHC
TQPDSDGLQQIIPVTYMNSSAALKAFCGRNGGIVCTSSNAHAVLEWAFARGKRVLFFPDQ
CCCCCCHHHHHCCEEEECCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHCCCEEEECCCH
HLGRNTARAMGIPLNEMPLWDPFKAQGGAADPADYARAKMILWKGFCSVHQRFTVEQVER
HCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ARKAYPGVKVIVHPECSMQVVDAADGTGSTAYIVKEIANAPAGSAIAVGTEINLVNRLAA
HHHHCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHH
QYPDKTVFCLDPVVCPCSTMYRIHPAYLAWALENLEAGNVVNRITVDEDTAREAKVALER
HCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHH
MLRVHP
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]