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The map label for this gene is mtrB [H]

Identifier: 213691594

GI number: 213691594

Start: 799906

End: 801897

Strand: Direct

Name: mtrB [H]

Synonym: Blon_0698

Alternate gene names: 213691594

Gene position: 799906-801897 (Clockwise)

Preceding gene: 213691593

Following gene: 213691595

Centisome position: 28.24

GC content: 60.24

Gene sequence:

>1992_bases
ATGAGTATCCCCGATAAGCAGTCAGGCGGCGTACCGCCGAGCAGCACGCCGAACGCCGCCCCGAACACGAATCCCATGCC
TGCAATGCCGCCGTTCGCCGCCCATTTCCAAGAGCGGAACGAACGTAAGAAAAACATGCTGATGCGGCATATCGACCGTA
TCTCGTTGAGCAGCAAGCTGGTGGCCTGCACCATCGCCGTGCTGCTCATCGGCGTGTCGGTGATTTCCTTCTCCATCCGC
GCGTTGGTGAACAACTACATGCTGCAGAAAACCGACACCCAGTTAAGCTCGCAAAGCCAGCTGGTGGTCAACAATATCGA
TCTGCTGTCAAGAAATGACTCATCGGGGCCGAACTCGTACTTTCTGCAGATTCAATATACCGACGGCACCAAAGACAAAG
AGGGCAATCCTCTGGTCGTGACCCCGCTGATGCCGCAGATGCAGGACGGTATCGTATCGGTGCCGATTCTTCCTACCTAT
GGTGATACCAGTGGCATCACGCTCGGCCAGGCATTCACTACGCAGGCAGTGGCCAAGCAGATCATCACGGTGCAGTCCGA
CAGTGCGGACAGCCAGAACGATCCGGCCAACGGAAACTCCAATTCCTCTGACACCATCACCAAGGTACTGGCCAACCCCA
CTGTCAATGCCAACCATGCCGCCATCGTCACGGCGAGGGCGCCATGGCGTATTCTGCCGGTGACCTTCCAGCAAAACGGC
AAGGACCGGGCCGTGGTGTACATCGGCTTGTCACTGGCCGACCAGATCGACACCGTCAACACACTCACCCGATACTGCAT
TGTGGTCGGCATCGCCGTGGTGCTGCTCGGCGGCTCCCTGTCCACGCTGATCATCCAGCACACGATGACGCCGCTGAAGC
GCATCGAGAAAACCGCTGCAAAGATTGCCGCCGGCGACCTGAGCCAGCGTATTCCTTCCGCGCCGGAAAACACCGAGGTC
GGCTCCCTGGCCGCCTCGCTGAACTCCATGCTCGCCCGAATAGAATCCAGTTTCCATGAGCAGGAGGAGACCACCGACAA
GATGAAACGGTTCGTCTCCGACGCCAGCCATGAGCTGCGCACCCCGTTGGCCGCCATCCATGGCTATGCGGAGCTGTATA
AGATGCAGCGCGATATGCCTGGTGCCTTGGAGCGTGCGGACGAGTCCATCGAACATATCGAACGGTCCAGCCAGCGCATG
ACGGTTCTTGTTGAGGATCTGCTGTCTTTGGCCCGTCTCGATGAGGGGCGCGGCATCGATGTGACCGGCACGGTGAAACT
CTCGTCGCTGGTCACCGACGCCGTCGATGACTTGCATGCGCTCGACCCGGACCGTGCCGTTCGCCGCATGCAGATTTCCC
TCGAACCGGCGCGCGATTTGAACCATCCCGCCGAATTCAACCTTGCCGAAGGCGATTGGCCCGAGGTTGTACTGCCCGGC
GACGCCTCTCGACTGCGCCAGGTGGTGACCAACATCGTGGGCAACATCCACCGCTACACGCCTGCCGATTCGCCTGCCGA
GGCCGCGCTCGGTGTGATGCCGGCCGCCATCGATCCAAGACAGCTCGCTCGCATGCCCGCCAGCGACGCGTCAATGCGGC
GGTTCATCGACGCCGCCGAAGTAGGTGCCTCGATGCAGACCGGCTATCGATATGCCGTATTGCGTTTCGTGGACCATGGC
CCCGGCGTGCCGCCTGAATCACGCTCGAAGATTTTCGAACGCTTCTACACCGCGGACCCGTCCCGTGCCCGAGAAAAGGG
CGGTACCGGTTTGGGCATGGCCATCGCGCAATCCGTGGTCAAAGCACATCACGGCTTTATCTGCGCCACCGGCACCGATG
GGGGAGGCCTGACCTTCACCGTGGTGCTGCCGATTGAGCAGATCGCCGCTCCTGAGCCCAAACAGTCCACCGGAAAAACC
AAGGACGCCAAACAGAAGACTTCTTGGTTCAGCTCTGAGCGTAAGACTCAGGCGACTCAGCCCAAAGCGTGA

Upstream 100 bases:

>100_bases
AGCGCAAGGTTACCCCGCTGATTGAAACCAAGCGCGGCATCGGATATATGATTCGCGAACCGAAGAACTAGTCGCCCCAT
CCATAACGCATCGTAATCTC

Downstream 100 bases:

>100_bases
GGTCAAGCCCTGTGAGGTAAACTGTACCTTCGGTTTACTATTTCCATTGAGGATTAAGGAAGGTTCGCAATGCCCACCGG
TCGAGTTCGTTGGTTTGACG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 663; Mature: 662

Protein sequence:

>663_residues
MSIPDKQSGGVPPSSTPNAAPNTNPMPAMPPFAAHFQERNERKKNMLMRHIDRISLSSKLVACTIAVLLIGVSVISFSIR
ALVNNYMLQKTDTQLSSQSQLVVNNIDLLSRNDSSGPNSYFLQIQYTDGTKDKEGNPLVVTPLMPQMQDGIVSVPILPTY
GDTSGITLGQAFTTQAVAKQIITVQSDSADSQNDPANGNSNSSDTITKVLANPTVNANHAAIVTARAPWRILPVTFQQNG
KDRAVVYIGLSLADQIDTVNTLTRYCIVVGIAVVLLGGSLSTLIIQHTMTPLKRIEKTAAKIAAGDLSQRIPSAPENTEV
GSLAASLNSMLARIESSFHEQEETTDKMKRFVSDASHELRTPLAAIHGYAELYKMQRDMPGALERADESIEHIERSSQRM
TVLVEDLLSLARLDEGRGIDVTGTVKLSSLVTDAVDDLHALDPDRAVRRMQISLEPARDLNHPAEFNLAEGDWPEVVLPG
DASRLRQVVTNIVGNIHRYTPADSPAEAALGVMPAAIDPRQLARMPASDASMRRFIDAAEVGASMQTGYRYAVLRFVDHG
PGVPPESRSKIFERFYTADPSRAREKGGTGLGMAIAQSVVKAHHGFICATGTDGGGLTFTVVLPIEQIAAPEPKQSTGKT
KDAKQKTSWFSSERKTQATQPKA

Sequences:

>Translated_663_residues
MSIPDKQSGGVPPSSTPNAAPNTNPMPAMPPFAAHFQERNERKKNMLMRHIDRISLSSKLVACTIAVLLIGVSVISFSIR
ALVNNYMLQKTDTQLSSQSQLVVNNIDLLSRNDSSGPNSYFLQIQYTDGTKDKEGNPLVVTPLMPQMQDGIVSVPILPTY
GDTSGITLGQAFTTQAVAKQIITVQSDSADSQNDPANGNSNSSDTITKVLANPTVNANHAAIVTARAPWRILPVTFQQNG
KDRAVVYIGLSLADQIDTVNTLTRYCIVVGIAVVLLGGSLSTLIIQHTMTPLKRIEKTAAKIAAGDLSQRIPSAPENTEV
GSLAASLNSMLARIESSFHEQEETTDKMKRFVSDASHELRTPLAAIHGYAELYKMQRDMPGALERADESIEHIERSSQRM
TVLVEDLLSLARLDEGRGIDVTGTVKLSSLVTDAVDDLHALDPDRAVRRMQISLEPARDLNHPAEFNLAEGDWPEVVLPG
DASRLRQVVTNIVGNIHRYTPADSPAEAALGVMPAAIDPRQLARMPASDASMRRFIDAAEVGASMQTGYRYAVLRFVDHG
PGVPPESRSKIFERFYTADPSRAREKGGTGLGMAIAQSVVKAHHGFICATGTDGGGLTFTVVLPIEQIAAPEPKQSTGKT
KDAKQKTSWFSSERKTQATQPKA
>Mature_662_residues
SIPDKQSGGVPPSSTPNAAPNTNPMPAMPPFAAHFQERNERKKNMLMRHIDRISLSSKLVACTIAVLLIGVSVISFSIRA
LVNNYMLQKTDTQLSSQSQLVVNNIDLLSRNDSSGPNSYFLQIQYTDGTKDKEGNPLVVTPLMPQMQDGIVSVPILPTYG
DTSGITLGQAFTTQAVAKQIITVQSDSADSQNDPANGNSNSSDTITKVLANPTVNANHAAIVTARAPWRILPVTFQQNGK
DRAVVYIGLSLADQIDTVNTLTRYCIVVGIAVVLLGGSLSTLIIQHTMTPLKRIEKTAAKIAAGDLSQRIPSAPENTEVG
SLAASLNSMLARIESSFHEQEETTDKMKRFVSDASHELRTPLAAIHGYAELYKMQRDMPGALERADESIEHIERSSQRMT
VLVEDLLSLARLDEGRGIDVTGTVKLSSLVTDAVDDLHALDPDRAVRRMQISLEPARDLNHPAEFNLAEGDWPEVVLPGD
ASRLRQVVTNIVGNIHRYTPADSPAEAALGVMPAAIDPRQLARMPASDASMRRFIDAAEVGASMQTGYRYAVLRFVDHGP
GVPPESRSKIFERFYTADPSRAREKGGTGLGMAIAQSVVKAHHGFICATGTDGGGLTFTVVLPIEQIAAPEPKQSTGKTK
DAKQKTSWFSSERKTQATQPKA

Specific function: Member of the two-component regulatory system mtrA/mtrB. Seems to function as a membrane-associated protein kinase that phosphorylates mtrA in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=340, Percent_Identity=29.4117647058824, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1786783, Length=400, Percent_Identity=26.75, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1790346, Length=394, Percent_Identity=26.6497461928934, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786600, Length=300, Percent_Identity=26.6666666666667, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787894, Length=332, Percent_Identity=25.3012048192771, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=362, Percent_Identity=26.2430939226519, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790551, Length=375, Percent_Identity=23.4666666666667, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71658; Mature: 71527

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIPDKQSGGVPPSSTPNAAPNTNPMPAMPPFAAHFQERNERKKNMLMRHIDRISLSSKL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VACTIAVLLIGVSVISFSIRALVNNYMLQKTDTQLSSQSQLVVNNIDLLSRNDSSGPNSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHEECCCCCCCCEE
FLQIQYTDGTKDKEGNPLVVTPLMPQMQDGIVSVPILPTYGDTSGITLGQAFTTQAVAKQ
EEEEEECCCCCCCCCCCEEEECCCCHHHCCEEEEEEECCCCCCCCEEECHHHHHHHHHHH
IITVQSDSADSQNDPANGNSNSSDTITKVLANPTVNANHAAIVTARAPWRILPVTFQQNG
HHEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECCCC
KDRAVVYIGLSLADQIDTVNTLTRYCIVVGIAVVLLGGSLSTLIIQHTMTPLKRIEKTAA
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KIAAGDLSQRIPSAPENTEVGSLAASLNSMLARIESSFHEQEETTDKMKRFVSDASHELR
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPLAAIHGYAELYKMQRDMPGALERADESIEHIERSSQRMTVLVEDLLSLARLDEGRGID
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VTGTVKLSSLVTDAVDDLHALDPDRAVRRMQISLEPARDLNHPAEFNLAEGDWPEVVLPG
EEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHEECCCHHCCCCCCCCCCCCCCCCCEEECC
DASRLRQVVTNIVGNIHRYTPADSPAEAALGVMPAAIDPRQLARMPASDASMRRFIDAAE
CHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHH
VGASMQTGYRYAVLRFVDHGPGVPPESRSKIFERFYTADPSRAREKGGTGLGMAIAQSVV
HCCHHHCCHHEEEHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHH
KAHHGFICATGTDGGGLTFTVVLPIEQIAAPEPKQSTGKTKDAKQKTSWFSSERKTQATQ
HHHCCEEEEECCCCCCEEEEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
PKA
CCC
>Mature Secondary Structure 
SIPDKQSGGVPPSSTPNAAPNTNPMPAMPPFAAHFQERNERKKNMLMRHIDRISLSSKL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VACTIAVLLIGVSVISFSIRALVNNYMLQKTDTQLSSQSQLVVNNIDLLSRNDSSGPNSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHEECCCCCCCCEE
FLQIQYTDGTKDKEGNPLVVTPLMPQMQDGIVSVPILPTYGDTSGITLGQAFTTQAVAKQ
EEEEEECCCCCCCCCCCEEEECCCCHHHCCEEEEEEECCCCCCCCEEECHHHHHHHHHHH
IITVQSDSADSQNDPANGNSNSSDTITKVLANPTVNANHAAIVTARAPWRILPVTFQQNG
HHEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECCCC
KDRAVVYIGLSLADQIDTVNTLTRYCIVVGIAVVLLGGSLSTLIIQHTMTPLKRIEKTAA
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KIAAGDLSQRIPSAPENTEVGSLAASLNSMLARIESSFHEQEETTDKMKRFVSDASHELR
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPLAAIHGYAELYKMQRDMPGALERADESIEHIERSSQRMTVLVEDLLSLARLDEGRGID
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VTGTVKLSSLVTDAVDDLHALDPDRAVRRMQISLEPARDLNHPAEFNLAEGDWPEVVLPG
EEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHEECCCHHCCCCCCCCCCCCCCCCCEEECC
DASRLRQVVTNIVGNIHRYTPADSPAEAALGVMPAAIDPRQLARMPASDASMRRFIDAAE
CHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHH
VGASMQTGYRYAVLRFVDHGPGVPPESRSKIFERFYTADPSRAREKGGTGLGMAIAQSVV
HCCHHHCCHHEEEHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHH
KAHHGFICATGTDGGGLTFTVVLPIEQIAAPEPKQSTGKTKDAKQKTSWFSSERKTQATQ
HHHCCEEEEECCCCCCEEEEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
PKA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA