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The map label for this gene is phoP [H]

Identifier: 213691593

GI number: 213691593

Start: 799145

End: 799876

Strand: Direct

Name: phoP [H]

Synonym: Blon_0697

Alternate gene names: 213691593

Gene position: 799145-799876 (Clockwise)

Preceding gene: 213691592

Following gene: 213691594

Centisome position: 28.21

GC content: 58.06

Gene sequence:

>732_bases
ATGAGTAAGCCTATTGAAGCATCGATTGTTGTTGTCGACGACGAGCCGTCCATCCGAGAACTGCTGGTCGCTTCCCTGCA
CTTCGCCGGATTCGAGGTAAACACCGCCGCTTCCGGTTCCGAAGCCATTGAGGTTATCGAAAAAGTGCAGCCTGATCTCA
TCGTGTTGGACGTCATGCTGCCTGACATCGATGGATTCACCGTCACCCGCCGTATCCGCCAGGAAGGCATTACCGCCCCT
GTGCTGTTCCTCACCGCTCGTGACGACACCCAAGACAAGATCATGGGCCTGACCGTCGGCGGTGACGATTACGTCACCAA
GCCGTTCAGCCTCGAGGAAGTCGTGGCTCGCATCCGCGCCATTCTGCGCCGTACCCGCGAACAGGTGGAAGATGACCCGA
TTATTCGCGTCGCCGACTTGGAAATCAACGAGGACTCCCACGACGTGACCCGTGCAGGGCAGCCGGTTGACCTGAGCCCT
ACCGAATACAAGCTGCTGCGCTACCTGATGGACAACGAGGGCCGAGTACTGTCCAAGGCACAGATTCTCGACCATGTCTG
GCAATACGACTGGGGCGGCGACGCAGCCATCGTCGAATCGTACATCTCCTACCTGCGCAAGAAAGTCGACGGCATCGAGG
TCGACGACGGCGAAGGCGGCAAGCGCAAGGTTACCCCGCTGATTGAAACCAAGCGCGGCATCGGATATATGATTCGCGAA
CCGAAGAACTAG

Upstream 100 bases:

>100_bases
GTGGTGATTCGTCGGCGCAAGGAGATCAAGAAGGATTCCAAGGCCGAACTCCAAGATGACATTCAGGAAACGCCCAGAAG
AGCACGACACTCTAGAAGGC

Downstream 100 bases:

>100_bases
TCGCCCCATCCATAACGCATCGTAATCTCATGAGTATCCCCGATAAGCAGTCAGGCGGCGTACCGCCGAGCAGCACGCCG
AACGCCGCCCCGAACACGAA

Product: two component transcriptional regulator, winged helix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSKPIEASIVVVDDEPSIRELLVASLHFAGFEVNTAASGSEAIEVIEKVQPDLIVLDVMLPDIDGFTVTRRIRQEGITAP
VLFLTARDDTQDKIMGLTVGGDDYVTKPFSLEEVVARIRAILRRTREQVEDDPIIRVADLEINEDSHDVTRAGQPVDLSP
TEYKLLRYLMDNEGRVLSKAQILDHVWQYDWGGDAAIVESYISYLRKKVDGIEVDDGEGGKRKVTPLIETKRGIGYMIRE
PKN

Sequences:

>Translated_243_residues
MSKPIEASIVVVDDEPSIRELLVASLHFAGFEVNTAASGSEAIEVIEKVQPDLIVLDVMLPDIDGFTVTRRIRQEGITAP
VLFLTARDDTQDKIMGLTVGGDDYVTKPFSLEEVVARIRAILRRTREQVEDDPIIRVADLEINEDSHDVTRAGQPVDLSP
TEYKLLRYLMDNEGRVLSKAQILDHVWQYDWGGDAAIVESYISYLRKKVDGIEVDDGEGGKRKVTPLIETKRGIGYMIRE
PKN
>Mature_242_residues
SKPIEASIVVVDDEPSIRELLVASLHFAGFEVNTAASGSEAIEVIEKVQPDLIVLDVMLPDIDGFTVTRRIRQEGITAPV
LFLTARDDTQDKIMGLTVGGDDYVTKPFSLEEVVARIRAILRRTREQVEDDPIIRVADLEINEDSHDVTRAGQPVDLSPT
EYKLLRYLMDNEGRVLSKAQILDHVWQYDWGGDAAIVESYISYLRKKVDGIEVDDGEGGKRKVTPLIETKRGIGYMIREP
KN

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=37.5, Blast_Score=156, Evalue=9e-40,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=36.5217391304348, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=34.3347639484979, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=34.061135371179, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=37.3913043478261, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1789402, Length=232, Percent_Identity=33.6206896551724, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1786911, Length=203, Percent_Identity=34.4827586206897, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789809, Length=207, Percent_Identity=30.4347826086957, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=32.0175438596491, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787375, Length=235, Percent_Identity=31.063829787234, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787229, Length=220, Percent_Identity=33.6363636363636, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI2367329, Length=236, Percent_Identity=34.7457627118644, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790863, Length=211, Percent_Identity=29.3838862559242, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=32.0754716981132, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI145693157, Length=119, Percent_Identity=36.1344537815126, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI145693140, Length=241, Percent_Identity=27.8008298755187, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790299, Length=120, Percent_Identity=32.5, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1788713, Length=112, Percent_Identity=32.1428571428571, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787487, Length=109, Percent_Identity=31.1926605504587, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1790437, Length=132, Percent_Identity=28.7878787878788, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27207; Mature: 27076

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPIEASIVVVDDEPSIRELLVASLHFAGFEVNTAASGSEAIEVIEKVQPDLIVLDVML
CCCCCEEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHCCCCEEEEEEEC
PDIDGFTVTRRIRQEGITAPVLFLTARDDTQDKIMGLTVGGDDYVTKPFSLEEVVARIRA
CCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
ILRRTREQVEDDPIIRVADLEINEDSHDVTRAGQPVDLSPTEYKLLRYLMDNEGRVLSKA
HHHHHHHHCCCCCEEEEEEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHH
QILDHVWQYDWGGDAAIVESYISYLRKKVDGIEVDDGEGGKRKVTPLIETKRGIGYMIRE
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCEECCHHHHHCCCCCEEEEC
PKN
CCC
>Mature Secondary Structure 
SKPIEASIVVVDDEPSIRELLVASLHFAGFEVNTAASGSEAIEVIEKVQPDLIVLDVML
CCCCEEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHCCCCEEEEEEEC
PDIDGFTVTRRIRQEGITAPVLFLTARDDTQDKIMGLTVGGDDYVTKPFSLEEVVARIRA
CCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
ILRRTREQVEDDPIIRVADLEINEDSHDVTRAGQPVDLSPTEYKLLRYLMDNEGRVLSKA
HHHHHHHHCCCCCEEEEEEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHH
QILDHVWQYDWGGDAAIVESYISYLRKKVDGIEVDDGEGGKRKVTPLIETKRGIGYMIRE
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCEECCHHHHHCCCCCEEEEC
PKN
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]