| Definition | Bifidobacterium longum subsp. infantis ATCC 15697, complete genome. |
|---|---|
| Accession | NC_011593 |
| Length | 2,832,748 |
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The map label for this gene is yqhE [C]
Identifier: 213691351
GI number: 213691351
Start: 510310
End: 511026
Strand: Direct
Name: yqhE [C]
Synonym: Blon_0442
Alternate gene names: 213691351
Gene position: 510310-511026 (Clockwise)
Preceding gene: 213691349
Following gene: 213691352
Centisome position: 18.01
GC content: 64.99
Gene sequence:
>717_bases ATGACCAACGGGCACATCAACCCCGCCAACGTGCCGGACATCGCCTTGAAAGACGGCCATTCCATTCCGCAGGTCGGCCT TGGCATCCTACGCATCGACGACGAGGGTGTGGTCCCCGTCGTCGAATCCGCGCTGGAAGCCGGCTACCGCCACATCGACG GTGCGGCCGGCTACAACAACGAAGCCGGCGTGGGTCGTGCGCTCGCCGCTTCCGGATACAACACCGGTGCCAAGCGCGAG ACCCTGTGGGTTACCGCCAAGCTGCGCGACGAAGGCATGGCACGTACGCTCGGCGTATGCAACTTCATGCCCGCCGATCT GAAGCGTCTGCACGAGGAGACCGGTGCATGGCCGGCCGTCAATCAGATTGAGCTGCATCCCACGTGGCAGCAGCGCGAAG TGGTGGCGTTCTGCAAGGAGCACGGCATCGCCGTGGAGGCCTACTCGCCGATGGCGCGTGGCGCCGACCTCAACGCCGGC GACGGTACCATCGAGAAGATCGCCGCCGCCCATGAGGTCAGCCCGGCCCAGGTGATTCTGCGTTGGCACATCGAAAACGG CACGATCATCATCCCCAAGTCCGTGCATGCCGACCGCCAGAAGGAGAATCTCAATCTGTTCGGCTTCGCCCTGACCGCCG ACGAACATGCCGCCATCGACGCCCTTGACGGCCCCACCCGCGCCGGCCACGACCCCCTCACCTTCACCTATGCGTGA
Upstream 100 bases:
>100_bases CCGGGCACAATCATGCCGTTTGGTTGCAGCACCCGCACATCGCCTGCATAACCGTGTACAGTGGCGTGTAGTTGCAGTAC ATGAAGGAGCATCGCACATC
Downstream 100 bases:
>100_bases TTGATGGCACGCCGTAACGCCCACTTTCGCCGTCGTTTCAACGCCTCCGGGCCGCTGGAGCGCGTGCTGATTCTCATCGT TCTCGCCGCAGCAATCGGCG
Product: aldo/keto reductase
Products: 2-keto-L-gulonate; NADP [C]
Alternate protein names: NA
Number of amino acids: Translated: 238; Mature: 237
Protein sequence:
>238_residues MTNGHINPANVPDIALKDGHSIPQVGLGILRIDDEGVVPVVESALEAGYRHIDGAAGYNNEAGVGRALAASGYNTGAKRE TLWVTAKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAVNQIELHPTWQQREVVAFCKEHGIAVEAYSPMARGADLNAG DGTIEKIAAAHEVSPAQVILRWHIENGTIIIPKSVHADRQKENLNLFGFALTADEHAAIDALDGPTRAGHDPLTFTYA
Sequences:
>Translated_238_residues MTNGHINPANVPDIALKDGHSIPQVGLGILRIDDEGVVPVVESALEAGYRHIDGAAGYNNEAGVGRALAASGYNTGAKRE TLWVTAKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAVNQIELHPTWQQREVVAFCKEHGIAVEAYSPMARGADLNAG DGTIEKIAAAHEVSPAQVILRWHIENGTIIIPKSVHADRQKENLNLFGFALTADEHAAIDALDGPTRAGHDPLTFTYA >Mature_237_residues TNGHINPANVPDIALKDGHSIPQVGLGILRIDDEGVVPVVESALEAGYRHIDGAAGYNNEAGVGRALAASGYNTGAKRET LWVTAKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAVNQIELHPTWQQREVVAFCKEHGIAVEAYSPMARGADLNAGD GTIEKIAAAHEVSPAQVILRWHIENGTIIIPKSVHADRQKENLNLFGFALTADEHAAIDALDGPTRAGHDPLTFTYA
Specific function: Reduction [C]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI310109922, Length=271, Percent_Identity=28.4132841328413, Blast_Score=120, Evalue=9e-28, Organism=Homo sapiens, GI300116271, Length=257, Percent_Identity=30.7392996108949, Blast_Score=118, Evalue=4e-27, Organism=Homo sapiens, GI223468663, Length=152, Percent_Identity=37.5, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI5174695, Length=150, Percent_Identity=32.6666666666667, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI93277124, Length=148, Percent_Identity=35.1351351351351, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI291291012, Length=152, Percent_Identity=36.1842105263158, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI5453543, Length=152, Percent_Identity=32.2368421052632, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI24497583, Length=155, Percent_Identity=32.258064516129, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI310109924, Length=152, Percent_Identity=32.2368421052632, Blast_Score=91, Evalue=7e-19, Organism=Homo sapiens, GI310109920, Length=152, Percent_Identity=32.2368421052632, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI45446745, Length=152, Percent_Identity=32.2368421052632, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI4503285, Length=152, Percent_Identity=32.2368421052632, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI4502049, Length=143, Percent_Identity=34.2657342657343, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI24497577, Length=159, Percent_Identity=30.188679245283, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI5174391, Length=159, Percent_Identity=30.188679245283, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI24497585, Length=166, Percent_Identity=28.9156626506024, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI300116273, Length=129, Percent_Identity=31.0077519379845, Blast_Score=82, Evalue=5e-16, Organism=Escherichia coli, GI87082198, Length=276, Percent_Identity=35.8695652173913, Blast_Score=173, Evalue=7e-45, Organism=Escherichia coli, GI1786400, Length=260, Percent_Identity=33.0769230769231, Blast_Score=121, Evalue=4e-29, Organism=Escherichia coli, GI1788081, Length=151, Percent_Identity=31.1258278145695, Blast_Score=64, Evalue=9e-12, Organism=Caenorhabditis elegans, GI71998625, Length=155, Percent_Identity=35.4838709677419, Blast_Score=107, Evalue=6e-24, Organism=Caenorhabditis elegans, GI17537077, Length=145, Percent_Identity=39.3103448275862, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17538386, Length=154, Percent_Identity=34.4155844155844, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17537075, Length=141, Percent_Identity=38.2978723404255, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17561300, Length=250, Percent_Identity=27.6, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17564128, Length=153, Percent_Identity=32.6797385620915, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17552492, Length=275, Percent_Identity=24, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17561298, Length=132, Percent_Identity=31.8181818181818, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17537079, Length=141, Percent_Identity=34.0425531914894, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17566692, Length=182, Percent_Identity=24.7252747252747, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17550248, Length=154, Percent_Identity=29.8701298701299, Blast_Score=74, Evalue=9e-14, Organism=Saccharomyces cerevisiae, GI6324694, Length=171, Percent_Identity=33.9181286549708, Blast_Score=97, Evalue=2e-21, Organism=Saccharomyces cerevisiae, GI6320576, Length=138, Percent_Identity=38.4057971014493, Blast_Score=95, Evalue=8e-21, Organism=Saccharomyces cerevisiae, GI6322556, Length=264, Percent_Identity=25.7575757575758, Blast_Score=93, Evalue=3e-20, Organism=Saccharomyces cerevisiae, GI6320079, Length=157, Percent_Identity=35.031847133758, Blast_Score=89, Evalue=6e-19, Organism=Saccharomyces cerevisiae, GI6319625, Length=142, Percent_Identity=32.3943661971831, Blast_Score=80, Evalue=2e-16, Organism=Saccharomyces cerevisiae, GI6321896, Length=160, Percent_Identity=35, Blast_Score=76, Evalue=5e-15, Organism=Drosophila melanogaster, GI24644950, Length=161, Percent_Identity=41.6149068322981, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI221378297, Length=161, Percent_Identity=41.6149068322981, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI24657054, Length=149, Percent_Identity=40.9395973154362, Blast_Score=115, Evalue=4e-26, Organism=Drosophila melanogaster, GI21356425, Length=146, Percent_Identity=36.986301369863, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI45553081, Length=129, Percent_Identity=41.0852713178295, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI281366140, Length=129, Percent_Identity=41.0852713178295, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI24662785, Length=134, Percent_Identity=36.5671641791045, Blast_Score=91, Evalue=8e-19, Organism=Drosophila melanogaster, GI24662781, Length=134, Percent_Identity=36.5671641791045, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24663317, Length=146, Percent_Identity=32.1917808219178, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI20129731, Length=139, Percent_Identity=33.0935251798561, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI24662789, Length=145, Percent_Identity=35.1724137931034, Blast_Score=86, Evalue=2e-17,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: NA
Molecular weight: Translated: 25563; Mature: 25432
Theoretical pI: Translated: 5.50; Mature: 5.50
Prosite motif: PS00798 ALDOKETO_REDUCTASE_1 ; PS00063 ALDOKETO_REDUCTASE_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTNGHINPANVPDIALKDGHSIPQVGLGILRIDDEGVVPVVESALEAGYRHIDGAAGYNN CCCCCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCHHCCCCCCCCCC EAGVGRALAASGYNTGAKRETLWVTAKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAV CCCCCCEEECCCCCCCCCCEEEEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCC NQIELHPTWQQREVVAFCKEHGIAVEAYSPMARGADLNAGDGTIEKIAAAHEVSPAQVIL CEEEECCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEE RWHIENGTIIIPKSVHADRQKENLNLFGFALTADEHAAIDALDGPTRAGHDPLTFTYA EEEECCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCEEECCCCCCCCCCCCEEEEEC >Mature Secondary Structure TNGHINPANVPDIALKDGHSIPQVGLGILRIDDEGVVPVVESALEAGYRHIDGAAGYNN CCCCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCHHCCCCCCCCCC EAGVGRALAASGYNTGAKRETLWVTAKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAV CCCCCCEEECCCCCCCCCCEEEEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCC NQIELHPTWQQREVVAFCKEHGIAVEAYSPMARGADLNAGDGTIEKIAAAHEVSPAQVIL CEEEECCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEE RWHIENGTIIIPKSVHADRQKENLNLFGFALTADEHAAIDALDGPTRAGHDPLTFTYA EEEECCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCEEECCCCCCCCCCCCEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: 2,5-diketo-D-gluconate; NADPH [C]
Specific reaction: 2,5-diketo-D-gluconate + NADPH = 2-keto-L-gulonate + NADP [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA