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The map label for this gene is yccK [H]

Identifier: 213691285

GI number: 213691285

Start: 431779

End: 432699

Strand: Direct

Name: yccK [H]

Synonym: Blon_0372

Alternate gene names: 213691285

Gene position: 431779-432699 (Clockwise)

Preceding gene: 213691284

Following gene: 213691286

Centisome position: 15.24

GC content: 63.63

Gene sequence:

>921_bases
ATGCTTAGGCTTGATCGTGGATATCGAGTTTCCATAAGTTTCACGAAGGGAATCACCATGGCATTGTTCCGTAACCTCGG
ACCGTTCTCCACCACCGCCATCGGCCACGGCGAAATGCCGCTGACCATCGAAAACAACCGCGGCCACGAGGTCGGCATCG
AAACCCTGCATGCCTCGCTGGACGCCGGTTGCCGCCACATCGACACCGCTTGGGCCTACTACTGCTCCGGCGGCGAGGAG
CAGACCGGTGAAAAGCTGGTGCGCGAGGCCCTTGAGACCTGGAAGGGGCCGAAGGACGAGGTGCTGGTGGCCACCAAGGT
GGGCCACTTCCGCAACTTCACCGACGGCCGCCCCACGTGGGATGTGGACGGTCGCCCGGAGAACCTGATTCGGCGCGGCA
AGGAGAGCGCACTGGCGCTCGGCGTGGACACCATCGACCTGCTGTACTTCCACCGCCCGGACCCGAAGGTGCCGTACAAC
GAGTCCATCGAAGCCATCAAGCAGCTGGTGGACGAGGGCGTGGCGCAGGAGGCCGGTATCTCCAACGCCTCCATCGAGCA
AATCGACATTGCGCGCGGCATTCTGGGCGACAAGCTCGTGGCCGTGCAGAACCAGTACTCGCCGATTCACCTGGAGACCC
AGGACACGCTCGACTACTGCGCCAAGGTCGGTCTGGCCTTCGTGTGCTGGAGCCCGCTCGGCGGCTACCGTCACCCCTAT
GATGAGACCAAGTTCGACCCGTTCCGCGAGGTCGCGGCGGCCCATGGCGTGAGCTACCAGCAGGTCGTGCTGGCATGGGA
GCTCGCCAAGGGAGATCACGTGTTCGTGATTCCCGGTGCGCACCGTCCCGAAACCATCCTCGACTCCCTGAAGGCCGACC
AGCTCGAACTCACCCCCGAAGAACTCGCCAAGCTCGGCTGA

Upstream 100 bases:

>100_bases
CTGAACTGGATATGAGTAAGTTGCGTTTTCTATTCCGTGAAGTTGCGGAAATTTCATAGATTGATTGTGCGGGCAGGCCG
AGAGTGTGAAATCCAACGGG

Downstream 100 bases:

>100_bases
ACTTTCTCAGCTCCCCCTTGTCAGGGGAGCTGTCTCGCGTAGCGAGACTGAGGGGTAGTCGCTGGAGTAGTCCCGCAAGG
AGATAATTATGCGTAAAAAA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MLRLDRGYRVSISFTKGITMALFRNLGPFSTTAIGHGEMPLTIENNRGHEVGIETLHASLDAGCRHIDTAWAYYCSGGEE
QTGEKLVREALETWKGPKDEVLVATKVGHFRNFTDGRPTWDVDGRPENLIRRGKESALALGVDTIDLLYFHRPDPKVPYN
ESIEAIKQLVDEGVAQEAGISNASIEQIDIARGILGDKLVAVQNQYSPIHLETQDTLDYCAKVGLAFVCWSPLGGYRHPY
DETKFDPFREVAAAHGVSYQQVVLAWELAKGDHVFVIPGAHRPETILDSLKADQLELTPEELAKLG

Sequences:

>Translated_306_residues
MLRLDRGYRVSISFTKGITMALFRNLGPFSTTAIGHGEMPLTIENNRGHEVGIETLHASLDAGCRHIDTAWAYYCSGGEE
QTGEKLVREALETWKGPKDEVLVATKVGHFRNFTDGRPTWDVDGRPENLIRRGKESALALGVDTIDLLYFHRPDPKVPYN
ESIEAIKQLVDEGVAQEAGISNASIEQIDIARGILGDKLVAVQNQYSPIHLETQDTLDYCAKVGLAFVCWSPLGGYRHPY
DETKFDPFREVAAAHGVSYQQVVLAWELAKGDHVFVIPGAHRPETILDSLKADQLELTPEELAKLG
>Mature_306_residues
MLRLDRGYRVSISFTKGITMALFRNLGPFSTTAIGHGEMPLTIENNRGHEVGIETLHASLDAGCRHIDTAWAYYCSGGEE
QTGEKLVREALETWKGPKDEVLVATKVGHFRNFTDGRPTWDVDGRPENLIRRGKESALALGVDTIDLLYFHRPDPKVPYN
ESIEAIKQLVDEGVAQEAGISNASIEQIDIARGILGDKLVAVQNQYSPIHLETQDTLDYCAKVGLAFVCWSPLGGYRHPY
DETKFDPFREVAAAHGVSYQQVVLAWELAKGDHVFVIPGAHRPETILDSLKADQLELTPEELAKLG

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI223468663, Length=280, Percent_Identity=26.7857142857143, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI24497577, Length=273, Percent_Identity=25.2747252747253, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI5174391, Length=273, Percent_Identity=25.2747252747253, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI291291012, Length=280, Percent_Identity=26.4285714285714, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI310109922, Length=263, Percent_Identity=25.0950570342205, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI5453543, Length=282, Percent_Identity=24.822695035461, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787674, Length=290, Percent_Identity=29.6551724137931, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87081735, Length=285, Percent_Identity=28.4210526315789, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI48994888, Length=294, Percent_Identity=26.530612244898, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786400, Length=255, Percent_Identity=27.4509803921569, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788081, Length=287, Percent_Identity=25.7839721254355, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324694, Length=257, Percent_Identity=26.4591439688716, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24644950, Length=289, Percent_Identity=28.0276816608997, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI221378297, Length=309, Percent_Identity=26.8608414239482, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24663317, Length=305, Percent_Identity=26.5573770491803, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 33909; Mature: 33909

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRLDRGYRVSISFTKGITMALFRNLGPFSTTAIGHGEMPLTIENNRGHEVGIETLHASL
CCCCCCCCEEEEEECCCHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHH
DAGCRHIDTAWAYYCSGGEEQTGEKLVREALETWKGPKDEVLVATKVGHFRNFTDGRPTW
HHCCHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCC
DVDGRPENLIRRGKESALALGVDTIDLLYFHRPDPKVPYNESIEAIKQLVDEGVAQEAGI
CCCCCHHHHHHCCCCCEEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCC
SNASIEQIDIARGILGDKLVAVQNQYSPIHLETQDTLDYCAKVGLAFVCWSPLGGYRHPY
CCCCHHHHHHHHHHHCCEEEEEECCCCCEEECCHHHHHHHHHHHHHEEEECCCCCCCCCC
DETKFDPFREVAAAHGVSYQQVVLAWELAKGDHVFVIPGAHRPETILDSLKADQLELTPE
CCCCCCHHHHHHHHHCCCHHHEEEEEEECCCCEEEEECCCCCCHHHHHHHCCCCEECCHH
ELAKLG
HHHHCC
>Mature Secondary Structure
MLRLDRGYRVSISFTKGITMALFRNLGPFSTTAIGHGEMPLTIENNRGHEVGIETLHASL
CCCCCCCCEEEEEECCCHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHH
DAGCRHIDTAWAYYCSGGEEQTGEKLVREALETWKGPKDEVLVATKVGHFRNFTDGRPTW
HHCCHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCC
DVDGRPENLIRRGKESALALGVDTIDLLYFHRPDPKVPYNESIEAIKQLVDEGVAQEAGI
CCCCCHHHHHHCCCCCEEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCC
SNASIEQIDIARGILGDKLVAVQNQYSPIHLETQDTLDYCAKVGLAFVCWSPLGGYRHPY
CCCCHHHHHHHHHHHCCEEEEEECCCCCEEECCHHHHHHHHHHHHHEEEECCCCCCCCCC
DETKFDPFREVAAAHGVSYQQVVLAWELAKGDHVFVIPGAHRPETILDSLKADQLELTPE
CCCCCCHHHHHHHHHCCCHHHEEEEEEECCCCEEEEECCCCCCHHHHHHHCCCCEECCHH
ELAKLG
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]