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The map label for this gene is rho [H]

Identifier: 213691185

GI number: 213691185

Start: 312476

End: 314539

Strand: Direct

Name: rho [H]

Synonym: Blon_0265

Alternate gene names: 213691185

Gene position: 312476-314539 (Clockwise)

Preceding gene: 213691184

Following gene: 213691190

Centisome position: 11.03

GC content: 63.91

Gene sequence:

>2064_bases
GTGGCAAATAGCCAGAATCTTGAGGATATGAAGCTGCCTGAGCTCAAAGAGCTCGCTAAACAGATGGGCCTGCGCGGCAC
GTCGACCATGCGCAAGCCCGAGCTGCGCGCCACCCTGCAGGCGGCGCGCAATGGTGGAGAGCCGCCGGCCGGTGTGACCG
TGCGCGCCCCCAAGGCCGCCAAAACCGCCAAGGTCGTCAAGGCTCCGCAGCCCGATGCCGCTGAGGCCAGCACCACAGAC
AATGCTGACGCGGCCACCCAGTCGCTGGCTCCAGCTCCGGCTGCCACGGAACCGCAGCTCGATTTGCCGCTTCCCGTGGC
CGACGATGCCAAGAAGGACGAGACCGAACCGCGACGCACCCGTCGTAAGGCCGCCGATGATGCCGCATTCGAACCGCGTG
CGGCCCGTCGTCGTCGCGATGACGACCAGTCCGATTTCGCTCGCCGCAAGCCGCGCAAGAAGGCCGATGAGGCCGGCGAT
CTGCTGGCCACGCTCGATTTGGGAGATGCAGCGCCTACCGAGCGTCGCCGCGAGCGCCATGAGGACGTGGAAGTTCCTCT
GATTCGCCGAGTCCGTGATGATGAGGACGAGCAGCCTCGCCGCCGCCGTCGCACTGCGGAAAACAGCGAAGAAACCGTGC
GTGACCTCGACGATATCCTGGCCACGCTGCCCACGCAGAAGCACGAGGAAACGGCCGAAGACGGCGAGCAAAACGACGAT
CACGAGTTTGTGCGTCGTAACCGCCGCGACCGTAGCGATCGTAACGATCGCGATAACCGTAATGATCGCAACGATTGCCG
TAACCGCCGCATGCGTGGCCGTGATCGCGACAACGCCGATGATGATCGTCGCTATGATGATCGCGATAATCGTAGCGATC
GCAATGACCGTGATAGCCGCCGCGAAGAGCCGCAGGAGGATCTGGTGCCGGTGGCCGGCATCGTCGACGTGCTCGACTCC
TACGCTTTTGTGCGCACTTCCGGCTACCTGCCAGGCCCGAACGACGTGTACGTTTCCATGGGCCAGGTCAAGAAGTACGG
TCTGCGCAAGGGCGATGCCGTCCATGGTTCGATTCGCGCCCCGCGCGAAGGCGACCGTCGCAACCAGCGCCAGAAGTTCG
TGCCGCTGCAGGCCATCGATTCCATCAACGGCCAAAGCGTTGAAGAAGCGCTCAACCGTCCGCAGTTCTCCAAGCTCACG
CCGCTGTACCCGCAGGAGCGTTTGAAGCAGGAGACCGCCCCGAACAAGCTCACCGGCCGTATCATGGACATCGTTTCCCC
GATCGGCAAGGGCCAGCGTGGTCTGATTGTCTCCCCGCCGAAGGCCGGTAAGACCATCACCCTGCAGAACATCGCCAACT
CCATCGCCGCCAACAACCCCGAGGTCCACCTTATGGTGGTGCTCGTGGACGAGCGCCCCGAAGAGGTCACCGATATGGAG
CGCACGGTCCAGGGCGAGGTCATTTCCTCCACCTTCGACCGTCCGGCCTCCGATCACACCACGGTTGCCGAACTGGCCAT
CGAACGCGCCAAGCGTCTTGTGGAGCTCGGCCAGGACGTGGTCGTACTGCTCGATTCCATGACCCGACTGGCTCGCGCTT
ACAACATCGCAGCCCCTGCCTCCGGCCGCATCCTGTCCGGTGGTGTGGACGCGCAGGCCCTCTACCCGCCGAAGAAGTTC
TTCGGCGCCGCCCGCAACATCGAGAACGGCGGTTCCCTGACCATCATCTCCTCCGCGCTGGTCGAGACCGGCTCCAAGAT
GGATGAGGTGATTTTCGAGGAGTTCAAGGGCACCGGCAACATGGAGCTGCGCCTGTCCCGCGAGCTGGCGGACAAACGAC
TGTTCCCGGCCATCGACATCAACGCTTCCGGCACCCGCCGCGAGGAGCTCATCACCAATCCGCAGGAACTGCCGGTCATC
TACCGTCTGCGTCGTCTGCTGGGAGGCATGGAGCCCGAGCAGGCCTACCAGACGCTGGTGCCGCGCCTCAAGAAGACCGC
CACCAATCGGGACTTCCTCGCCGCCATCGTGCAGCAGCAGAGCGGAGCCGTGAACGGCAACTGA

Upstream 100 bases:

>100_bases
GACTCAGAGACGCAGCGAACATTCATGAGCGGTGCGACCGCAATAATCACTCTTAACGCCTGGATAGGCATGGGCCTGTT
CGGTATGGAAAGGGCAACCA

Downstream 100 bases:

>100_bases
GGTTGCCGTTCAGGCAAACCCGGTGGGCTTGCCGACGGCGACGCCTGAGTGAGGCGGCAGCCGAACGAAGGTTGGATCGA
GTCCGCGCGTAGCGTGGTCC

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 687; Mature: 686

Protein sequence:

>687_residues
MANSQNLEDMKLPELKELAKQMGLRGTSTMRKPELRATLQAARNGGEPPAGVTVRAPKAAKTAKVVKAPQPDAAEASTTD
NADAATQSLAPAPAATEPQLDLPLPVADDAKKDETEPRRTRRKAADDAAFEPRAARRRRDDDQSDFARRKPRKKADEAGD
LLATLDLGDAAPTERRRERHEDVEVPLIRRVRDDEDEQPRRRRRTAENSEETVRDLDDILATLPTQKHEETAEDGEQNDD
HEFVRRNRRDRSDRNDRDNRNDRNDCRNRRMRGRDRDNADDDRRYDDRDNRSDRNDRDSRREEPQEDLVPVAGIVDVLDS
YAFVRTSGYLPGPNDVYVSMGQVKKYGLRKGDAVHGSIRAPREGDRRNQRQKFVPLQAIDSINGQSVEEALNRPQFSKLT
PLYPQERLKQETAPNKLTGRIMDIVSPIGKGQRGLIVSPPKAGKTITLQNIANSIAANNPEVHLMVVLVDERPEEVTDME
RTVQGEVISSTFDRPASDHTTVAELAIERAKRLVELGQDVVVLLDSMTRLARAYNIAAPASGRILSGGVDAQALYPPKKF
FGAARNIENGGSLTIISSALVETGSKMDEVIFEEFKGTGNMELRLSRELADKRLFPAIDINASGTRREELITNPQELPVI
YRLRRLLGGMEPEQAYQTLVPRLKKTATNRDFLAAIVQQQSGAVNGN

Sequences:

>Translated_687_residues
MANSQNLEDMKLPELKELAKQMGLRGTSTMRKPELRATLQAARNGGEPPAGVTVRAPKAAKTAKVVKAPQPDAAEASTTD
NADAATQSLAPAPAATEPQLDLPLPVADDAKKDETEPRRTRRKAADDAAFEPRAARRRRDDDQSDFARRKPRKKADEAGD
LLATLDLGDAAPTERRRERHEDVEVPLIRRVRDDEDEQPRRRRRTAENSEETVRDLDDILATLPTQKHEETAEDGEQNDD
HEFVRRNRRDRSDRNDRDNRNDRNDCRNRRMRGRDRDNADDDRRYDDRDNRSDRNDRDSRREEPQEDLVPVAGIVDVLDS
YAFVRTSGYLPGPNDVYVSMGQVKKYGLRKGDAVHGSIRAPREGDRRNQRQKFVPLQAIDSINGQSVEEALNRPQFSKLT
PLYPQERLKQETAPNKLTGRIMDIVSPIGKGQRGLIVSPPKAGKTITLQNIANSIAANNPEVHLMVVLVDERPEEVTDME
RTVQGEVISSTFDRPASDHTTVAELAIERAKRLVELGQDVVVLLDSMTRLARAYNIAAPASGRILSGGVDAQALYPPKKF
FGAARNIENGGSLTIISSALVETGSKMDEVIFEEFKGTGNMELRLSRELADKRLFPAIDINASGTRREELITNPQELPVI
YRLRRLLGGMEPEQAYQTLVPRLKKTATNRDFLAAIVQQQSGAVNGN
>Mature_686_residues
ANSQNLEDMKLPELKELAKQMGLRGTSTMRKPELRATLQAARNGGEPPAGVTVRAPKAAKTAKVVKAPQPDAAEASTTDN
ADAATQSLAPAPAATEPQLDLPLPVADDAKKDETEPRRTRRKAADDAAFEPRAARRRRDDDQSDFARRKPRKKADEAGDL
LATLDLGDAAPTERRRERHEDVEVPLIRRVRDDEDEQPRRRRRTAENSEETVRDLDDILATLPTQKHEETAEDGEQNDDH
EFVRRNRRDRSDRNDRDNRNDRNDCRNRRMRGRDRDNADDDRRYDDRDNRSDRNDRDSRREEPQEDLVPVAGIVDVLDSY
AFVRTSGYLPGPNDVYVSMGQVKKYGLRKGDAVHGSIRAPREGDRRNQRQKFVPLQAIDSINGQSVEEALNRPQFSKLTP
LYPQERLKQETAPNKLTGRIMDIVSPIGKGQRGLIVSPPKAGKTITLQNIANSIAANNPEVHLMVVLVDERPEEVTDMER
TVQGEVISSTFDRPASDHTTVAELAIERAKRLVELGQDVVVLLDSMTRLARAYNIAAPASGRILSGGVDAQALYPPKKFF
GAARNIENGGSLTIISSALVETGSKMDEVIFEEFKGTGNMELRLSRELADKRLFPAIDINASGTRREELITNPQELPVIY
RLRRLLGGMEPEQAYQTLVPRLKKTATNRDFLAAIVQQQSGAVNGN

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=367, Percent_Identity=56.1307901907357, Blast_Score=423, Evalue=1e-119,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 76813; Mature: 76682

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANSQNLEDMKLPELKELAKQMGLRGTSTMRKPELRATLQAARNGGEPPAGVTVRAPKAA
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCHH
KTAKVVKAPQPDAAEASTTDNADAATQSLAPAPAATEPQLDLPLPVADDAKKDETEPRRT
HHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
RRKAADDAAFEPRAARRRRDDDQSDFARRKPRKKADEAGDLLATLDLGDAAPTERRRERH
HHHHCCCCCCCCHHHHHCCCCCHHHHHHHCCHHHHHHHCCEEEEEECCCCCCHHHHHHHH
EDVEVPLIRRVRDDEDEQPRRRRRTAENSEETVRDLDDILATLPTQKHEETAEDGEQNDD
CCCCCHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
HEFVRRNRRDRSDRNDRDNRNDRNDCRNRRMRGRDRDNADDDRRYDDRDNRSDRNDRDSR
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
REEPQEDLVPVAGIVDVLDSYAFVRTSGYLPGPNDVYVSMGQVKKYGLRKGDAVHGSIRA
HCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCC
PREGDRRNQRQKFVPLQAIDSINGQSVEEALNRPQFSKLTPLYPQERLKQETAPNKLTGR
CCCCHHHHHHHHCCCHHHHHCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHH
IMDIVSPIGKGQRGLIVSPPKAGKTITLQNIANSIAANNPEVHLMVVLVDERPEEVTDME
HHHHHHHHCCCCCCEEECCCCCCCEEEHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHH
RTVQGEVISSTFDRPASDHTTVAELAIERAKRLVELGQDVVVLLDSMTRLARAYNIAAPA
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCC
SGRILSGGVDAQALYPPKKFFGAARNIENGGSLTIISSALVETGSKMDEVIFEEFKGTGN
CCCEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHCCCHHHHHHHHHHCCCCC
MELRLSRELADKRLFPAIDINASGTRREELITNPQELPVIYRLRRLLGGMEPEQAYQTLV
EEEEEHHHHHHHHCCCEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
PRLKKTATNRDFLAAIVQQQSGAVNGN
HHHHHHCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ANSQNLEDMKLPELKELAKQMGLRGTSTMRKPELRATLQAARNGGEPPAGVTVRAPKAA
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCHH
KTAKVVKAPQPDAAEASTTDNADAATQSLAPAPAATEPQLDLPLPVADDAKKDETEPRRT
HHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
RRKAADDAAFEPRAARRRRDDDQSDFARRKPRKKADEAGDLLATLDLGDAAPTERRRERH
HHHHCCCCCCCCHHHHHCCCCCHHHHHHHCCHHHHHHHCCEEEEEECCCCCCHHHHHHHH
EDVEVPLIRRVRDDEDEQPRRRRRTAENSEETVRDLDDILATLPTQKHEETAEDGEQNDD
CCCCCHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
HEFVRRNRRDRSDRNDRDNRNDRNDCRNRRMRGRDRDNADDDRRYDDRDNRSDRNDRDSR
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
REEPQEDLVPVAGIVDVLDSYAFVRTSGYLPGPNDVYVSMGQVKKYGLRKGDAVHGSIRA
HCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCC
PREGDRRNQRQKFVPLQAIDSINGQSVEEALNRPQFSKLTPLYPQERLKQETAPNKLTGR
CCCCHHHHHHHHCCCHHHHHCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHH
IMDIVSPIGKGQRGLIVSPPKAGKTITLQNIANSIAANNPEVHLMVVLVDERPEEVTDME
HHHHHHHHCCCCCCEEECCCCCCCEEEHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHH
RTVQGEVISSTFDRPASDHTTVAELAIERAKRLVELGQDVVVLLDSMTRLARAYNIAAPA
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCC
SGRILSGGVDAQALYPPKKFFGAARNIENGGSLTIISSALVETGSKMDEVIFEEFKGTGN
CCCEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHCCCHHHHHHHHHHCCCCC
MELRLSRELADKRLFPAIDINASGTRREELITNPQELPVIYRLRRLLGGMEPEQAYQTLV
EEEEEHHHHHHHHCCCEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
PRLKKTATNRDFLAAIVQQQSGAVNGN
HHHHHHCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8557681; 8051015 [H]