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The map label for this gene is murG

Identifier: 213159077

GI number: 213159077

Start: 3906387

End: 3907484

Strand: Reverse

Name: murG

Synonym: AB57_3787

Alternate gene names: 213159077

Gene position: 3907484-3906387 (Counterclockwise)

Preceding gene: 213159078

Following gene: 213159076

Centisome position: 96.47

GC content: 43.62

Gene sequence:

>1098_bases
GTGACCGATTCACAGCAAAGCAAACCTAAACATGTCATGATGATGGCTGCCGGTACTGGTGGACATGTTTTTCCAGCCCT
CGCCGTAGCCAAACAACTTCAACAACAAGGTTGTCAAGTTTCATGGTTAGCCACGCCAACAGGTATGGAAAATCGTTTAT
TAAAAGATCAAAATATTCCAATTTATCAAATTGATATTCAAGGTGTGCGTGGAAACGGAGTGATCCGTAAACTTGCTGCA
CCTTTTAAAATTTTAAAAGCAACTTTTAGTGCAATGCGCTATATGAAACAGCTTAAAGTGGATGCTGTTGCAGGCTTTGG
GGGATATGTGGCAGGCCCGGGTGGGCTAGCAGCGCGTTTATTAGGTATTCCTGTTCTCATCCACGAGCAAAATGCGGTTG
CAGGATTTACCAATGCACAGTTATCCCGTGTTGCTAAAGTGGTATGTGAAGCGTTTCCAAATACATTTCCTGCTAGCGAA
AAAGTAGTGACAACCGGCAATCCGGTACGTCGTGAAATCACTGATATCTTAAGTCCAAAGTGGCGCTATGATGAACGCGA
GCAAGCGGGTAAGCCGTTAAATATTTTAATTGTGGGCGGATCTTTAGGTGCAAAAGCACTGAATGAACGCTTACCTCCGG
CATTAAAACAACTTGAAGTTCCACTGAATATTTTCCATCAATGTGGTCAGCAACAGGTTGAAGCAACTCAAGCTTTGTAC
GCAGATGCGCCAGCAAATTTGACCGTACAGGTTTTGCCGTTTATTGAAGATATGGCGAAAGCTTATAGCGAAGCAGACCT
GATTATTTGCCGTGCTGGTGCTTTAACTGTGACAGAAGTAGCAACAGCTGGTGTTGCAGCAGTTTTTGTACCGCTTCCTA
TTGCGGTGGATGACCACCAAACTGCAAATGCCAAATTTCTGGCCGATGTCGGTGCTGCAAAAATTTGCCAGCAATCGACT
ATGACACCAGAAGTTTTAAATCAATTGTTTACTACGCTGATGAATCGCCAATTACTTACAGAAATGGCAGTGAAAGCGCG
TCAACATGCCCAACCAAATGCAACTCAGCATGTGGTTGATCTTATCCAAAAAATGTAA

Upstream 100 bases:

>100_bases
AGTGAAATTCGCTTTTCGTTAATGAAGCTTTAGGATTAAAATAAACGGCTACAAAAATAGATGACAATTTCCATTGTTTT
TTGAGTTGAAGAATTAGACC

Downstream 100 bases:

>100_bases
TCGGATTTACTATGTCTCCAACAACAGCTGCGAACCAAGCAAAAAAACTGATTAAAGTGCCTGAAATGCGCCGTATCAAA
CACATTCATTTTGTGGGAAT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTDSQQSKPKHVMMMAAGTGGHVFPALAVAKQLQQQGCQVSWLATPTGMENRLLKDQNIPIYQIDIQGVRGNGVIRKLAA
PFKILKATFSAMRYMKQLKVDAVAGFGGYVAGPGGLAARLLGIPVLIHEQNAVAGFTNAQLSRVAKVVCEAFPNTFPASE
KVVTTGNPVRREITDILSPKWRYDEREQAGKPLNILIVGGSLGAKALNERLPPALKQLEVPLNIFHQCGQQQVEATQALY
ADAPANLTVQVLPFIEDMAKAYSEADLIICRAGALTVTEVATAGVAAVFVPLPIAVDDHQTANAKFLADVGAAKICQQST
MTPEVLNQLFTTLMNRQLLTEMAVKARQHAQPNATQHVVDLIQKM

Sequences:

>Translated_365_residues
MTDSQQSKPKHVMMMAAGTGGHVFPALAVAKQLQQQGCQVSWLATPTGMENRLLKDQNIPIYQIDIQGVRGNGVIRKLAA
PFKILKATFSAMRYMKQLKVDAVAGFGGYVAGPGGLAARLLGIPVLIHEQNAVAGFTNAQLSRVAKVVCEAFPNTFPASE
KVVTTGNPVRREITDILSPKWRYDEREQAGKPLNILIVGGSLGAKALNERLPPALKQLEVPLNIFHQCGQQQVEATQALY
ADAPANLTVQVLPFIEDMAKAYSEADLIICRAGALTVTEVATAGVAAVFVPLPIAVDDHQTANAKFLADVGAAKICQQST
MTPEVLNQLFTTLMNRQLLTEMAVKARQHAQPNATQHVVDLIQKM
>Mature_364_residues
TDSQQSKPKHVMMMAAGTGGHVFPALAVAKQLQQQGCQVSWLATPTGMENRLLKDQNIPIYQIDIQGVRGNGVIRKLAAP
FKILKATFSAMRYMKQLKVDAVAGFGGYVAGPGGLAARLLGIPVLIHEQNAVAGFTNAQLSRVAKVVCEAFPNTFPASEK
VVTTGNPVRREITDILSPKWRYDEREQAGKPLNILIVGGSLGAKALNERLPPALKQLEVPLNIFHQCGQQQVEATQALYA
DAPANLTVQVLPFIEDMAKAYSEADLIICRAGALTVTEVATAGVAAVFVPLPIAVDDHQTANAKFLADVGAAKICQQSTM
TPEVLNQLFTTLMNRQLLTEMAVKARQHAQPNATQHVVDLIQKM

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=356, Percent_Identity=43.8202247191011, Blast_Score=274, Evalue=5e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_ACIB3 (B7GV73)

Other databases:

- EMBL:   CP001172
- RefSeq:   YP_002324086.1
- ProteinModelPortal:   B7GV73
- SMR:   B7GV73
- GeneID:   7057383
- GenomeReviews:   CP001172_GR
- KEGG:   abb:ABBFA_000145
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39350; Mature: 39219

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSQQSKPKHVMMMAAGTGGHVFPALAVAKQLQQQGCQVSWLATPTGMENRLLKDQNIP
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCCCC
IYQIDIQGVRGNGVIRKLAAPFKILKATFSAMRYMKQLKVDAVAGFGGYVAGPGGLAARL
EEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LGIPVLIHEQNAVAGFTNAQLSRVAKVVCEAFPNTFPASEKVVTTGNPVRREITDILSPK
HCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHCCC
WRYDEREQAGKPLNILIVGGSLGAKALNERLPPALKQLEVPLNIFHQCGQQQVEATQALY
CCCCCHHHCCCCEEEEEECCCCCHHHHHHHCCHHHHHHCCCHHHHHHCCHHHHHHHHHHH
ADAPANLTVQVLPFIEDMAKAYSEADLIICRAGALTVTEVATAGVAAVFVPLPIAVDDHQ
CCCCCCCEEEHHHHHHHHHHHHCCCCEEEEECCCEEHHHHHHHHHHEEEEECCEEECCCC
TANAKFLADVGAAKICQQSTMTPEVLNQLFTTLMNRQLLTEMAVKARQHAQPNATQHVVD
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LIQKM
HHHCC
>Mature Secondary Structure 
TDSQQSKPKHVMMMAAGTGGHVFPALAVAKQLQQQGCQVSWLATPTGMENRLLKDQNIP
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCCCC
IYQIDIQGVRGNGVIRKLAAPFKILKATFSAMRYMKQLKVDAVAGFGGYVAGPGGLAARL
EEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LGIPVLIHEQNAVAGFTNAQLSRVAKVVCEAFPNTFPASEKVVTTGNPVRREITDILSPK
HCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHCCC
WRYDEREQAGKPLNILIVGGSLGAKALNERLPPALKQLEVPLNIFHQCGQQQVEATQALY
CCCCCHHHCCCCEEEEEECCCCCHHHHHHHCCHHHHHHCCCHHHHHHCCHHHHHHHHHHH
ADAPANLTVQVLPFIEDMAKAYSEADLIICRAGALTVTEVATAGVAAVFVPLPIAVDDHQ
CCCCCCCEEEHHHHHHHHHHHHCCCCEEEEECCCEEHHHHHHHHHHEEEEECCEEECCCC
TANAKFLADVGAAKICQQSTMTPEVLNQLFTTLMNRQLLTEMAVKARQHAQPNATQHVVD
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LIQKM
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA