BacMap

Definition	Acinetobacter baumannii AB0057, complete genome.
Accession	NC_011586
Length	4,050,513

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The map label for this gene is fabG [H]

Identifier: 213158531

GI number: 213158531

Start: 2577159

End: 2577929

Strand: Reverse

Name: fabG [H]

Synonym: AB57_2482

Alternate gene names: 213158531

Gene position: 2577929-2577159 (Counterclockwise)

Preceding gene: 213158535

Following gene: 213158530

Centisome position: 63.64

GC content: 43.97

Gene sequence:

>771_bases
ATGAAAATTCAAGGAAAACATTTCGTGATTACAGGTGGTGGCTCTGGTTTAGGAGCTGCAACGGCTGAATATTTAGTAAA
GCAGGGTGCCTCAGTCACATTAGTAGACATGAATGTAGAAGCAGGTGAGCAGCAGGCGAAACAGTTAGGACCAAAAGCTG
ACTTTGTAAAACTTGATGTAACCGATGAAGCAGCTGCTGAGCAGTTCTTTAAAGATGTGTTGGTTAAACATGGTCATTTG
CATGGTTTGGTGAACTGTGCCGGTATTGGCCCTTCTGCAAAAGTAGTTGGCCGTGAGGGCGTTCATGACTTGGGGTTATT
TGCAAAGACTTTAAATATTAATGTCACAGGTACATTTAACATGTTGCGTTTTGCAGCAGATGCAATGAGCAAAAACACGG
TTGAAGAAGGTGAAGAGGACCGTGGCATCATTGTGAACACTGCTTCTGTTGCAGCATTTGACGGTCAAATTGGACAGGCA
GCTTATTCTGCATCAAAAGGCGCTATTGTGGCGATGACTTTGCCGATTGCTCGTGAGCTAGCACGACATGCCATTCGTAT
TATGACCATTGCACCGGGAATTATGGAAACTCCAATGCTTAAGGGTATGCCACAAAATGTACAAGATGCTTTGGGGCAAA
TGGTGCCGTACCCATCTCGTTTAGGAAAACCAGAAGAGTTTGCTCGTTTGGTTGCCCATATTGCTGAAAACTCTTACTTA
AATGGTGAAGTCATCCGTCTAGATGGTGCAATTCGCATGGCAGCAAAATAA

Upstream 100 bases:

>100_bases
AAGCTGCAAGCATTTTGAGGTTTTTTGAAATTGTATCGGAAAAAAACAACTTTTACTCTCACTACTAGGCTTAAAGAACA
TTTCTATAGGACATTACATA

Downstream 100 bases:

>100_bases
TAAAATAAGGATGTTGAAATGATTCTAAATGCTGAACAAAGTATGGTTCAGGAGATGATGCGTAACTATGCGCAAAATCA
GTTAAAACCAACTGCTGCAC

Product: short-chain dehydrogenase/reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKIQGKHFVITGGGSGLGAATAEYLVKQGASVTLVDMNVEAGEQQAKQLGPKADFVKLDVTDEAAAEQFFKDVLVKHGHL
HGLVNCAGIGPSAKVVGREGVHDLGLFAKTLNINVTGTFNMLRFAADAMSKNTVEEGEEDRGIIVNTASVAAFDGQIGQA
AYSASKGAIVAMTLPIARELARHAIRIMTIAPGIMETPMLKGMPQNVQDALGQMVPYPSRLGKPEEFARLVAHIAENSYL
NGEVIRLDGAIRMAAK

Sequences:

>Translated_256_residues
MKIQGKHFVITGGGSGLGAATAEYLVKQGASVTLVDMNVEAGEQQAKQLGPKADFVKLDVTDEAAAEQFFKDVLVKHGHL
HGLVNCAGIGPSAKVVGREGVHDLGLFAKTLNINVTGTFNMLRFAADAMSKNTVEEGEEDRGIIVNTASVAAFDGQIGQA
AYSASKGAIVAMTLPIARELARHAIRIMTIAPGIMETPMLKGMPQNVQDALGQMVPYPSRLGKPEEFARLVAHIAENSYL
NGEVIRLDGAIRMAAK
>Mature_256_residues
MKIQGKHFVITGGGSGLGAATAEYLVKQGASVTLVDMNVEAGEQQAKQLGPKADFVKLDVTDEAAAEQFFKDVLVKHGHL
HGLVNCAGIGPSAKVVGREGVHDLGLFAKTLNINVTGTFNMLRFAADAMSKNTVEEGEEDRGIIVNTASVAAFDGQIGQA
AYSASKGAIVAMTLPIARELARHAIRIMTIAPGIMETPMLKGMPQNVQDALGQMVPYPSRLGKPEEFARLVAHIAENSYL
NGEVIRLDGAIRMAAK

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=52.755905511811, Blast_Score=248, Evalue=3e-66,
Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=50, Blast_Score=225, Evalue=3e-59,
Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=31.2741312741313, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=29.0983606557377, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI31542939, Length=263, Percent_Identity=30.4182509505703, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI224922801, Length=178, Percent_Identity=35.3932584269663, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI59889578, Length=207, Percent_Identity=28.0193236714976, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=27.734375, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=27.710843373494, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4503817, Length=253, Percent_Identity=28.0632411067194, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=27.906976744186, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=26.4591439688716, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI166795268, Length=220, Percent_Identity=29.0909090909091, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=25.3787878787879, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=257, Percent_Identity=28.7937743190661, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082160, Length=260, Percent_Identity=30.3846153846154, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082100, Length=269, Percent_Identity=28.996282527881, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786812, Length=271, Percent_Identity=29.1512915129151, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1789208, Length=265, Percent_Identity=29.0566037735849, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=32, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790717, Length=268, Percent_Identity=28.3582089552239, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=28.3464566929134, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=27.6264591439689, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=27.5590551181102, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI2367365, Length=255, Percent_Identity=30.1960784313725, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=249, Percent_Identity=48.1927710843374, Blast_Score=226, Evalue=8e-60,
Organism=Caenorhabditis elegans, GI17555706, Length=258, Percent_Identity=31.7829457364341, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=28.740157480315, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=27.3408239700375, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=270, Percent_Identity=27.4074074074074, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=267, Percent_Identity=27.3408239700375, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=261, Percent_Identity=28.3524904214559, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=29.3233082706767, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=27.6923076923077, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=275, Percent_Identity=28.7272727272727, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=274, Percent_Identity=25.5474452554745, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=26.4925373134328, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=273, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=27.3408239700375, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=27.4074074074074, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=208, Percent_Identity=28.8461538461538, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=29.5880149812734, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=27.1375464684015, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=273, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=259, Percent_Identity=26.6409266409266, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=266, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322227, Length=230, Percent_Identity=25.6521739130435, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=253, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=205, Percent_Identity=28.780487804878, Blast_Score=62, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17737361, Length=252, Percent_Identity=54.3650793650794, Blast_Score=248, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=31.5175097276265, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=30.5019305019305, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=27.6, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=28.7937743190661, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=28.6274509803922, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=27.6923076923077, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21356301, Length=207, Percent_Identity=30.9178743961353, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221331218, Length=258, Percent_Identity=25.968992248062, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24665243, Length=212, Percent_Identity=27.3584905660377, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221331216, Length=259, Percent_Identity=25.8687258687259, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24665247, Length=213, Percent_Identity=27.2300469483568, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27080; Mature: 27080

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIQGKHFVITGGGSGLGAATAEYLVKQGASVTLVDMNVEAGEQQAKQLGPKADFVKLDV
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCCCCCEEEEEC
TDEAAAEQFFKDVLVKHGHLHGLVNCAGIGPSAKVVGREGVHDLGLFAKTLNINVTGTFN
CCHHHHHHHHHHHHHHCCCHHEEEEEECCCCCCEEECCCCCHHHHHEEEEEEEEEEEHHH
MLRFAADAMSKNTVEEGEEDRGIIVNTASVAAFDGQIGQAAYSASKGAIVAMTLPIAREL
HHHHHHHHHHCCCHHCCCCCCCEEEEECEEEEECCCCCHHHHCCCCCEEEEEEHHHHHHH
ARHAIRIMTIAPGIMETPMLKGMPQNVQDALGQMVPYPSRLGKPEEFARLVAHIAENSYL
HHHHEEEEEECCCHHHCCHHCCCCCHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHCCCC
NGEVIRLDGAIRMAAK
CCEEEEECCEEEECCC
>Mature Secondary Structure
MKIQGKHFVITGGGSGLGAATAEYLVKQGASVTLVDMNVEAGEQQAKQLGPKADFVKLDV
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCCCCCEEEEEC
TDEAAAEQFFKDVLVKHGHLHGLVNCAGIGPSAKVVGREGVHDLGLFAKTLNINVTGTFN
CCHHHHHHHHHHHHHHCCCHHEEEEEECCCCCCEEECCCCCHHHHHEEEEEEEEEEEHHH
MLRFAADAMSKNTVEEGEEDRGIIVNTASVAAFDGQIGQAAYSASKGAIVAMTLPIAREL
HHHHHHHHHHCCCHHCCCCCCCEEEEECEEEEECCCCCHHHHCCCCCEEEEEEHHHHHHH
ARHAIRIMTIAPGIMETPMLKGMPQNVQDALGQMVPYPSRLGKPEEFARLVAHIAENSYL
HHHHEEEEEECCCHHHCCHHCCCCCHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHCCCC
NGEVIRLDGAIRMAAK
CCEEEEECCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]