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The map label for this gene is caiD [C]

Identifier: 213157963

GI number: 213157963

Start: 3566900

End: 3567733

Strand: Reverse

Name: caiD [C]

Synonym: AB57_3457

Alternate gene names: 213157963

Gene position: 3567733-3566900 (Counterclockwise)

Preceding gene: 213157964

Following gene: 213157962

Centisome position: 88.08

GC content: 43.29

Gene sequence:

>834_bases
ATGACACTTTCAGCATCGCTTCATATAGATATTGATGACAGCATTCAATTAGAACAAGACGGCAGTATTTTATATCTTTG
GTTAAACCGACCAGAGAGCCGTAATGCCATGAACTTGAATATGGTTAATGCGATTCAACAAGTTTTTACTGCCATTCGTG
ATGATCTTTCAATTCGTGCAGTCATCATTCGTGGTGAAGGTGGGACTTTCTGCGCAGGTGGTGATATTAAAGACATGGCT
GCTTTACGTGTTGAAGCAACTAACGTTGGTAGTCTACAACCTTATACTAATTTTAACCGCCGTTTTGGTGCCATGCTTGA
GCAAGTTGAAGCTGCACCACAGACTGTTGTGGTCATTTTAGAAAGTGCGGTGTTAGGTGGAGGTTTTGGGCTGGCATGTG
TTTCTGATGTTGCCATCAGTCGTGATAATGCGCAGTTTGGTTTACCTGAAACTGGGCTTGGTGTGATTCCTGCACAAATT
GCTCCTTTTGTGGTGAAACGTATTGGCCTGACTCAGGCACGTAGGCTGGCTTTACTCGGCATGCGTTTTGAAGGGCATAC
AGCACTGAGTGTCGGTGTGGTTCATCAAATTGCACATAATGAAATTGAACTTGAACAAGCTTTACAAGAAACAATTCAGC
AAATTAAACGAGCAGCTCCTCAAGCTTCACGTGTGACTAAAGCACTGTTACATCGAACACTCAATGAACCTTTAAATCAG
CTGCTAGATGATGCTGCACAGCAGTTTGCTCAAGCGGTTGGTAGTGCTGAAGGACAAGAAGGAACGATGGCTTTTATCCA
GAAACGGTTACCAAATTGGGCCGATGAAACATAA

Upstream 100 bases:

>100_bases
CGTTTAGGCTCTATTGGCGGTGGCGCAGATGAGATTATGTTGGGGATTATCTGTAAGTTGATGGATATTTTACCAAAAAA
ACAAAAATAAGGAATCAGCC

Downstream 100 bases:

>100_bases
GAGATAAGGATAAAAATAATGAAATTTTCAAAAATACTGGTTGCCAATCGTGGTGAAATTGCAGTTCGAGTTATGCAAAC
AGCCAAGGCAATGGGTTACC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MTLSASLHIDIDDSIQLEQDGSILYLWLNRPESRNAMNLNMVNAIQQVFTAIRDDLSIRAVIIRGEGGTFCAGGDIKDMA
ALRVEATNVGSLQPYTNFNRRFGAMLEQVEAAPQTVVVILESAVLGGGFGLACVSDVAISRDNAQFGLPETGLGVIPAQI
APFVVKRIGLTQARRLALLGMRFEGHTALSVGVVHQIAHNEIELEQALQETIQQIKRAAPQASRVTKALLHRTLNEPLNQ
LLDDAAQQFAQAVGSAEGQEGTMAFIQKRLPNWADET

Sequences:

>Translated_277_residues
MTLSASLHIDIDDSIQLEQDGSILYLWLNRPESRNAMNLNMVNAIQQVFTAIRDDLSIRAVIIRGEGGTFCAGGDIKDMA
ALRVEATNVGSLQPYTNFNRRFGAMLEQVEAAPQTVVVILESAVLGGGFGLACVSDVAISRDNAQFGLPETGLGVIPAQI
APFVVKRIGLTQARRLALLGMRFEGHTALSVGVVHQIAHNEIELEQALQETIQQIKRAAPQASRVTKALLHRTLNEPLNQ
LLDDAAQQFAQAVGSAEGQEGTMAFIQKRLPNWADET
>Mature_276_residues
TLSASLHIDIDDSIQLEQDGSILYLWLNRPESRNAMNLNMVNAIQQVFTAIRDDLSIRAVIIRGEGGTFCAGGDIKDMAA
LRVEATNVGSLQPYTNFNRRFGAMLEQVEAAPQTVVVILESAVLGGGFGLACVSDVAISRDNAQFGLPETGLGVIPAQIA
PFVVKRIGLTQARRLALLGMRFEGHTALSVGVVHQIAHNEIELEQALQETIQQIKRAAPQASRVTKALLHRTLNEPLNQL
LDDAAQQFAQAVGSAEGQEGTMAFIQKRLPNWADET

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4502327, Length=264, Percent_Identity=26.8939393939394, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI194097323, Length=263, Percent_Identity=23.574144486692, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI37594471, Length=200, Percent_Identity=27, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI37594469, Length=200, Percent_Identity=27, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI70995211, Length=230, Percent_Identity=27.8260869565217, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI31542718, Length=261, Percent_Identity=24.1379310344828, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI68989263, Length=210, Percent_Identity=25.7142857142857, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI221142681, Length=270, Percent_Identity=30, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787659, Length=252, Percent_Identity=28.968253968254, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788597, Length=254, Percent_Identity=28.740157480315, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1787660, Length=260, Percent_Identity=26.9230769230769, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI87082183, Length=249, Percent_Identity=26.9076305220884, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788682, Length=247, Percent_Identity=23.8866396761134, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25145438, Length=253, Percent_Identity=26.8774703557312, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17535521, Length=275, Percent_Identity=24.3636363636364, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17554946, Length=276, Percent_Identity=25, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI25144157, Length=279, Percent_Identity=24.0143369175627, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25144160, Length=267, Percent_Identity=24.3445692883895, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17540714, Length=188, Percent_Identity=28.7234042553192, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17549921, Length=221, Percent_Identity=25.3393665158371, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560910, Length=196, Percent_Identity=24.4897959183673, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17536985, Length=241, Percent_Identity=24.896265560166, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=271, Percent_Identity=23.2472324723247, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24653139, Length=260, Percent_Identity=27.3076923076923, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571729, Length=257, Percent_Identity=27.2373540856031, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI28571730, Length=257, Percent_Identity=27.2373540856031, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI19922422, Length=261, Percent_Identity=20.3065134099617, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129971, Length=253, Percent_Identity=24.1106719367589, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24653477, Length=253, Percent_Identity=24.1106719367589, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19920382, Length=256, Percent_Identity=25, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 30023; Mature: 29892

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSASLHIDIDDSIQLEQDGSILYLWLNRPESRNAMNLNMVNAIQQVFTAIRDDLSIRA
CCEEEEEEEECCCCEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEE
VIIRGEGGTFCAGGDIKDMAALRVEATNVGSLQPYTNFNRRFGAMLEQVEAAPQTVVVIL
EEEECCCCCEECCCCHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
ESAVLGGGFGLACVSDVAISRDNAQFGLPETGLGVIPAQIAPFVVKRIGLTQARRLALLG
HHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHE
MRFEGHTALSVGVVHQIAHNEIELEQALQETIQQIKRAAPQASRVTKALLHRTLNEPLNQ
EEECCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LLDDAAQQFAQAVGSAEGQEGTMAFIQKRLPNWADET
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TLSASLHIDIDDSIQLEQDGSILYLWLNRPESRNAMNLNMVNAIQQVFTAIRDDLSIRA
CEEEEEEEECCCCEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEE
VIIRGEGGTFCAGGDIKDMAALRVEATNVGSLQPYTNFNRRFGAMLEQVEAAPQTVVVIL
EEEECCCCCEECCCCHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
ESAVLGGGFGLACVSDVAISRDNAQFGLPETGLGVIPAQIAPFVVKRIGLTQARRLALLG
HHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHE
MRFEGHTALSVGVVHQIAHNEIELEQALQETIQQIKRAAPQASRVTKALLHRTLNEPLNQ
EEECCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LLDDAAQQFAQAVGSAEGQEGTMAFIQKRLPNWADET
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA