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The map label for this gene is yngJ [H]

Identifier: 213157964

GI number: 213157964

Start: 3567744

End: 3568901

Strand: Reverse

Name: yngJ [H]

Synonym: AB57_3458

Alternate gene names: 213157964

Gene position: 3568901-3567744 (Counterclockwise)

Preceding gene: 213157965

Following gene: 213157963

Centisome position: 88.11

GC content: 43.18

Gene sequence:

>1158_bases
ATGAAATTTACTGCCGAACATGAAGCATTACGTCGCACAGCGCGTCAATTTGTTGAAAATGAACTGAATCCGAATATTCC
GGAATGGGAAGAAGCTGGACGTTTCCCGATCCACGATGTATTTAAAAAGATGGGTGATCTTGGCCTATTGGGGATTTGTA
AGCCTGAGGAAAATGGTGGTCTGGCTTTAGATTACTCTTATAACTTGGTTGTTGCTGAAGAAATTGGACGCGCAGCTTGC
GGCGGTGTGCCTTTAGCCATTGGTGTACAAACCGATATGGCAACACCTGCTTTGGCGCGTTTTGGTAGCAAAGAATTACG
TGATGAGTTTTTAACACCAGCCATTGCTGGAGAATATGTTGCCTCAATTGCGGTATCGGAAGTGCATGCTGGTTCGGATG
TTGCTGCTATTAAAACGACTGCTAAAAAAGATGGCGATGACTATGTCATTAACGGCAGCAAAATGTGGATTACCAACTCA
CTGCAGGCCGATTTCTTCTGTCTTTTAGCCAACACATCTGACGATAAACCACATGTTAATAAGTCGATGATTATTGTGCC
AGCCAAAACTAAAGGGATTAGTTTTTCAGAGCCGTTAAATAAATTAGGGATGCGTTCAACGACCACAGCGCAGGTTTATT
TAGACAATGTACGTGTACCTCAGCGTAACTTGGTTGGCGTTGAAGGTATGGGCTTCATGATGCAGATGATGCAATTTCAG
GAAGAGCGTTTATGGGCTTGTGCTAATGCGATTGGTGGTTTGGAAAATTTAATTCAAAAGACTATCGCCTATACCAAAGA
GCGTACGACATTTGGTCAACCACTCATTAATAACCAATATATCCATTTTCGTTTTGCCGAACTCATGACTGAAGTAGAAG
CGCTTAAAGCCTTAACCTACCAAGCGTGTGAACAGCATATTGCGGGTGAAGATGTGACTAAGCTGGCATCTATGGCAAAG
CTCAAAGCAGGCCGTTTAAGCCGTGAAGTTGCCGATAGCTGTCTACAATATTGGGGGGGCAATGGCTTTATGTGGGATAA
CCCTGCATCCCAGCTATATCGTGATGGTCGTTTAGGCTCTATTGGCGGTGGCGCAGATGAGATTATGTTGGGGATTATCT
GTAAGTTGATGGATATTTTACCAAAAAAACAAAAATAA

Upstream 100 bases:

>100_bases
TTATGAAGCACAGCAACGCGATCTAAATCCGACCCGTTTTGGTGTGTCTCGTTTTTAATCAATCTTTACCGTAATTAAAA
AAATTAATAGGAACAACACC

Downstream 100 bases:

>100_bases
GGAATCAGCCATGACACTTTCAGCATCGCTTCATATAGATATTGATGACAGCATTCAATTAGAACAAGACGGCAGTATTT
TATATCTTTGGTTAAACCGA

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MKFTAEHEALRRTARQFVENELNPNIPEWEEAGRFPIHDVFKKMGDLGLLGICKPEENGGLALDYSYNLVVAEEIGRAAC
GGVPLAIGVQTDMATPALARFGSKELRDEFLTPAIAGEYVASIAVSEVHAGSDVAAIKTTAKKDGDDYVINGSKMWITNS
LQADFFCLLANTSDDKPHVNKSMIIVPAKTKGISFSEPLNKLGMRSTTTAQVYLDNVRVPQRNLVGVEGMGFMMQMMQFQ
EERLWACANAIGGLENLIQKTIAYTKERTTFGQPLINNQYIHFRFAELMTEVEALKALTYQACEQHIAGEDVTKLASMAK
LKAGRLSREVADSCLQYWGGNGFMWDNPASQLYRDGRLGSIGGGADEIMLGIICKLMDILPKKQK

Sequences:

>Translated_385_residues
MKFTAEHEALRRTARQFVENELNPNIPEWEEAGRFPIHDVFKKMGDLGLLGICKPEENGGLALDYSYNLVVAEEIGRAAC
GGVPLAIGVQTDMATPALARFGSKELRDEFLTPAIAGEYVASIAVSEVHAGSDVAAIKTTAKKDGDDYVINGSKMWITNS
LQADFFCLLANTSDDKPHVNKSMIIVPAKTKGISFSEPLNKLGMRSTTTAQVYLDNVRVPQRNLVGVEGMGFMMQMMQFQ
EERLWACANAIGGLENLIQKTIAYTKERTTFGQPLINNQYIHFRFAELMTEVEALKALTYQACEQHIAGEDVTKLASMAK
LKAGRLSREVADSCLQYWGGNGFMWDNPASQLYRDGRLGSIGGGADEIMLGIICKLMDILPKKQK
>Mature_385_residues
MKFTAEHEALRRTARQFVENELNPNIPEWEEAGRFPIHDVFKKMGDLGLLGICKPEENGGLALDYSYNLVVAEEIGRAAC
GGVPLAIGVQTDMATPALARFGSKELRDEFLTPAIAGEYVASIAVSEVHAGSDVAAIKTTAKKDGDDYVINGSKMWITNS
LQADFFCLLANTSDDKPHVNKSMIIVPAKTKGISFSEPLNKLGMRSTTTAQVYLDNVRVPQRNLVGVEGMGFMMQMMQFQ
EERLWACANAIGGLENLIQKTIAYTKERTTFGQPLINNQYIHFRFAELMTEVEALKALTYQACEQHIAGEDVTKLASMAK
LKAGRLSREVADSCLQYWGGNGFMWDNPASQLYRDGRLGSIGGGADEIMLGIICKLMDILPKKQK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=375, Percent_Identity=33.3333333333333, Blast_Score=218, Evalue=9e-57,
Organism=Homo sapiens, GI4557233, Length=369, Percent_Identity=34.1463414634146, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI4501859, Length=376, Percent_Identity=31.3829787234043, Blast_Score=205, Evalue=6e-53,
Organism=Homo sapiens, GI226958412, Length=369, Percent_Identity=31.4363143631436, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=32.9815303430079, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=32.9815303430079, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI226958414, Length=333, Percent_Identity=32.1321321321321, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI7656849, Length=379, Percent_Identity=30.0791556728232, Blast_Score=175, Evalue=5e-44,
Organism=Homo sapiens, GI76496475, Length=370, Percent_Identity=27.5675675675676, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI4557235, Length=370, Percent_Identity=27.5675675675676, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI21361497, Length=348, Percent_Identity=27.5862068965517, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI38505218, Length=376, Percent_Identity=27.1276595744681, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI48976061, Length=287, Percent_Identity=28.2229965156794, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI211971008, Length=287, Percent_Identity=28.2229965156794, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI7669494, Length=349, Percent_Identity=26.0744985673352, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI4503943, Length=349, Percent_Identity=26.0744985673352, Blast_Score=105, Evalue=8e-23,
Organism=Escherichia coli, GI87081958, Length=377, Percent_Identity=29.973474801061, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1786223, Length=331, Percent_Identity=28.0966767371601, Blast_Score=134, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17551932, Length=376, Percent_Identity=48.4042553191489, Blast_Score=377, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17505929, Length=376, Percent_Identity=47.8723404255319, Blast_Score=367, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17508101, Length=378, Percent_Identity=33.0687830687831, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17538396, Length=374, Percent_Identity=33.4224598930481, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17506239, Length=367, Percent_Identity=32.6975476839237, Blast_Score=207, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI17570075, Length=378, Percent_Identity=33.0687830687831, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17534899, Length=375, Percent_Identity=30.9333333333333, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17569725, Length=375, Percent_Identity=29.6, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI71990804, Length=276, Percent_Identity=36.231884057971, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17533517, Length=378, Percent_Identity=29.6296296296296, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71982178, Length=268, Percent_Identity=32.8358208955224, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=33.1896551724138, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71985184, Length=359, Percent_Identity=27.5766016713092, Blast_Score=137, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17531909, Length=242, Percent_Identity=32.2314049586777, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71985192, Length=305, Percent_Identity=26.8852459016393, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17534353, Length=357, Percent_Identity=26.0504201680672, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17562446, Length=289, Percent_Identity=24.9134948096886, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17531913, Length=179, Percent_Identity=30.1675977653631, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21356377, Length=367, Percent_Identity=32.425068119891, Blast_Score=215, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24646207, Length=367, Percent_Identity=33.5149863760218, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24666513, Length=375, Percent_Identity=32.8, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI21355753, Length=378, Percent_Identity=30.952380952381, Blast_Score=188, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=31.7460317460317, Blast_Score=185, Evalue=4e-47,
Organism=Drosophila melanogaster, GI281363737, Length=333, Percent_Identity=29.4294294294294, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI19920834, Length=306, Percent_Identity=29.0849673202614, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42402; Mature: 42402

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTAEHEALRRTARQFVENELNPNIPEWEEAGRFPIHDVFKKMGDLGLLGICKPEENGG
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHCCCCEEEEECCCCCCC
LALDYSYNLVVAEEIGRAACGGVPLAIGVQTDMATPALARFGSKELRDEFLTPAIAGEYV
EEEEEECCEEEHHHHCHHHHCCCCEEEECCCCCCCHHHHHCCCHHHHHHHCCHHHHHHHH
ASIAVSEVHAGSDVAAIKTTAKKDGDDYVINGSKMWITNSLQADFFCLLANTSDDKPHVN
HHHHHHHHCCCCCHHEEEHHHCCCCCCEEECCCEEEEECCCCCCEEEEEECCCCCCCCCC
KSMIIVPAKTKGISFSEPLNKLGMRSTTTAQVYLDNVRVPQRNLVGVEGMGFMMQMMQFQ
CCEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
EERLWACANAIGGLENLIQKTIAYTKERTTFGQPLINNQYIHFRFAELMTEVEALKALTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
QACEQHIAGEDVTKLASMAKLKAGRLSREVADSCLQYWGGNGFMWDNPASQLYRDGRLGS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCC
IGGGADEIMLGIICKLMDILPKKQK
CCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKFTAEHEALRRTARQFVENELNPNIPEWEEAGRFPIHDVFKKMGDLGLLGICKPEENGG
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHCCCCEEEEECCCCCCC
LALDYSYNLVVAEEIGRAACGGVPLAIGVQTDMATPALARFGSKELRDEFLTPAIAGEYV
EEEEEECCEEEHHHHCHHHHCCCCEEEECCCCCCCHHHHHCCCHHHHHHHCCHHHHHHHH
ASIAVSEVHAGSDVAAIKTTAKKDGDDYVINGSKMWITNSLQADFFCLLANTSDDKPHVN
HHHHHHHHCCCCCHHEEEHHHCCCCCCEEECCCEEEEECCCCCCEEEEEECCCCCCCCCC
KSMIIVPAKTKGISFSEPLNKLGMRSTTTAQVYLDNVRVPQRNLVGVEGMGFMMQMMQFQ
CCEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
EERLWACANAIGGLENLIQKTIAYTKERTTFGQPLINNQYIHFRFAELMTEVEALKALTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
QACEQHIAGEDVTKLASMAKLKAGRLSREVADSCLQYWGGNGFMWDNPASQLYRDGRLGS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCC
IGGGADEIMLGIICKLMDILPKKQK
CCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]