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The map label for this gene is pdxA [H]

Identifier: 213157956

GI number: 213157956

Start: 3560921

End: 3561895

Strand: Reverse

Name: pdxA [H]

Synonym: AB57_3450

Alternate gene names: 213157956

Gene position: 3561895-3560921 (Counterclockwise)

Preceding gene: 213157962

Following gene: 213157955

Centisome position: 87.94

GC content: 41.54

Gene sequence:

>975_bases
GTGATTGTGCTGCCTTTATATGTCACTTCCGGTGAACCTGCCGGTATTGGTCCAGATATTTGTTTAAGTCTGGCAAAACG
GGTTGATGAACGTCCTGTTGTGGTTTTGGCTGATCGAAATTTATTACAACAACGCGCTCAAAAGCTTGGTCTAGACATTA
AATTTTTAGAGTATAGCGGACAAGCTGAATCGTCTTTGCAAGGCGAGCTTTATATAGAACATGTACCCCTAGAAACTATA
GTCGTTGATGGACAGCTTAATGCTGCTAATGCCGCTTATGTATTAGAGCAATTACGTCGCTCAGCTGATTATGCTATGTC
TGGTAAGAGCGTCGGTGTAGCCACTGCTCCTGTTCAAAAGTCGGTGATTAATGATGCAGGGATTTTATTTAGTGGACATA
CTGAATATTATCAAGAATTTGCAGGCGTAGAGCGTGTTGTTATGATGCTGGCAACGAAAACGTTGCGGGTGGCTCTGGCG
ACCACTCATTTACCATTAAGAGATGTTGCAGATGCAATTACCAAAGAACGCTTGCATCAAGTGATTGATATTTTACTTCA
CGACTTAAAAACCAAGTTTAAAATTAATGATCCTCGAGTCTTAGTATGTGGGTTAAATCCTCATGCAGGCGAAGATGGTT
ATTTGGGACGTGAAGAGATTGATACGATCAATCCGGTACTTGAGAGCTACCGGTCACAGGGAGTTAAATTAAGTTTAAGT
TTGCCAGCTGATACTTTATTTACGCCTGAACATCTTAAAAATGCTGACGCTGTTCTTGCGATGTACCATGATCAAGGCTT
ACCTGTGTTAAAATCACAGGGTTTTGGTGAAGCAATCAATATCACATTGGGCTTACCATTTATTCGAACTTCGGTCGATC
ATGGTACTGCTCTGTCTTTAGCTGGGACAGGATTGGCAAAAAGCTCAAGTTTAAATGTCGCTGTCGATTTAGCTTTATCC
TTGGCAGCGAGTTAA

Upstream 100 bases:

>100_bases
CAATCACAAGAAAAATCCCATATAAGCTACATAATTTTATCCCTAATCCGATGAATGTAGGATATGTTAAAATAATTCAA
ATTTTAGAGATGTGTCGGGG

Downstream 100 bases:

>100_bases
ATTTTTCATGTTGGAAATGTTCTATGTATCAAATTAATGCCCTAAACCCGAAAGATGAAGGGCATAAAGCTCGTAAACGT
TTTGGTCAAAACTTCTTACA

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MIVLPLYVTSGEPAGIGPDICLSLAKRVDERPVVVLADRNLLQQRAQKLGLDIKFLEYSGQAESSLQGELYIEHVPLETI
VVDGQLNAANAAYVLEQLRRSADYAMSGKSVGVATAPVQKSVINDAGILFSGHTEYYQEFAGVERVVMMLATKTLRVALA
TTHLPLRDVADAITKERLHQVIDILLHDLKTKFKINDPRVLVCGLNPHAGEDGYLGREEIDTINPVLESYRSQGVKLSLS
LPADTLFTPEHLKNADAVLAMYHDQGLPVLKSQGFGEAINITLGLPFIRTSVDHGTALSLAGTGLAKSSSLNVAVDLALS
LAAS

Sequences:

>Translated_324_residues
MIVLPLYVTSGEPAGIGPDICLSLAKRVDERPVVVLADRNLLQQRAQKLGLDIKFLEYSGQAESSLQGELYIEHVPLETI
VVDGQLNAANAAYVLEQLRRSADYAMSGKSVGVATAPVQKSVINDAGILFSGHTEYYQEFAGVERVVMMLATKTLRVALA
TTHLPLRDVADAITKERLHQVIDILLHDLKTKFKINDPRVLVCGLNPHAGEDGYLGREEIDTINPVLESYRSQGVKLSLS
LPADTLFTPEHLKNADAVLAMYHDQGLPVLKSQGFGEAINITLGLPFIRTSVDHGTALSLAGTGLAKSSSLNVAVDLALS
LAAS
>Mature_324_residues
MIVLPLYVTSGEPAGIGPDICLSLAKRVDERPVVVLADRNLLQQRAQKLGLDIKFLEYSGQAESSLQGELYIEHVPLETI
VVDGQLNAANAAYVLEQLRRSADYAMSGKSVGVATAPVQKSVINDAGILFSGHTEYYQEFAGVERVVMMLATKTLRVALA
TTHLPLRDVADAITKERLHQVIDILLHDLKTKFKINDPRVLVCGLNPHAGEDGYLGREEIDTINPVLESYRSQGVKLSLS
LPADTLFTPEHLKNADAVLAMYHDQGLPVLKSQGFGEAINITLGLPFIRTSVDHGTALSLAGTGLAKSSSLNVAVDLALS
LAAS

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=318, Percent_Identity=59.748427672956, Blast_Score=363, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 34902; Mature: 34902

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLPLYVTSGEPAGIGPDICLSLAKRVDERPVVVLADRNLLQQRAQKLGLDIKFLEYSG
CEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHCCEEEEEEECC
QAESSLQGELYIEHVPLETIVVDGQLNAANAAYVLEQLRRSADYAMSGKSVGVATAPVQK
CCCCCCCCEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHCCHHCCCCCCCEEECCHHH
SVINDAGILFSGHTEYYQEFAGVERVVMMLATKTLRVALATTHLPLRDVADAITKERLHQ
HHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHH
VIDILLHDLKTKFKINDPRVLVCGLNPHAGEDGYLGREEIDTINPVLESYRSQGVKLSLS
HHHHHHHHHHHCEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEE
LPADTLFTPEHLKNADAVLAMYHDQGLPVLKSQGFGEAINITLGLPFIRTSVDHGTALSL
CCCCCCCCHHHHCCCCEEEEEEECCCCCEEECCCCCCEEEEEEECCHHEECCCCCCEEEE
AGTGLAKSSSLNVAVDLALSLAAS
ECCCCCCCCCCEEEEEEEEHHCCC
>Mature Secondary Structure
MIVLPLYVTSGEPAGIGPDICLSLAKRVDERPVVVLADRNLLQQRAQKLGLDIKFLEYSG
CEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHCCEEEEEEECC
QAESSLQGELYIEHVPLETIVVDGQLNAANAAYVLEQLRRSADYAMSGKSVGVATAPVQK
CCCCCCCCEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHCCHHCCCCCCCEEECCHHH
SVINDAGILFSGHTEYYQEFAGVERVVMMLATKTLRVALATTHLPLRDVADAITKERLHQ
HHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHH
VIDILLHDLKTKFKINDPRVLVCGLNPHAGEDGYLGREEIDTINPVLESYRSQGVKLSLS
HHHHHHHHHHHCEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEE
LPADTLFTPEHLKNADAVLAMYHDQGLPVLKSQGFGEAINITLGLPFIRTSVDHGTALSL
CCCCCCCCHHHHCCCCEEEEEEECCCCCEEECCCCCCEEEEEEECCHHEECCCCCCEEEE
AGTGLAKSSSLNVAVDLALSLAAS
ECCCCCCCCCCEEEEEEEEHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA