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The map label for this gene is ltrA [H]

Identifier: 213157584

GI number: 213157584

Start: 2360316

End: 2361218

Strand: Direct

Name: ltrA [H]

Synonym: AB57_2277

Alternate gene names: 213157584

Gene position: 2360316-2361218 (Clockwise)

Preceding gene: 213157582

Following gene: 213157586

Centisome position: 58.27

GC content: 38.21

Gene sequence:

>903_bases
ATGCTCACAGATCTTGATGATTTTTATTGTTTTGCCCTTGTTGTTGAGCATGGTGGATTTAGTGCCGCCGAACGTGTTAC
GGATATTCCAAAATCAAAATTAAGTCGTCGTGTTTATAACTTAGAGGAAAATTTAGGGGTTCGCTTAATTCAGCGCAGTT
CTCGTCATTTTGCAGTTACCGATATTGGTATGGATATTTATAGACACGCCCAAGTCATGATGAATGCCGCACAAGCAGCT
CATGATTTGGTTGATCACTTAAGTATTCAACCTAGGGGGGTAGTCAAAGTAAGCGTTCCTGTAGACATAGCACAAAATCA
GCTACCCAAAATTTTACCGGCATTTTTAAAAAATAATCCTGAAATTCGTTTACAACTTATTGTAAGTAATCGACGCGTTG
ATGTAATTAATGAAGGAATTGATATTGCTCTACGGGTCAGATCTAAACTAGATGATGACCCTAGTCTGGTACTAAGACAG
TTTGCGCTAATAGAACAAAGTCTCTTTGCAAGCCAAGCTTATTTAAATGAGTTTGGTAATATTAAGTCACCTGATGAGTT
AAGTGATCATCGTATTTTAAGCTTGTCTGAAGAGCATTTAGATCAACAATTTATATTGCATGGTCCAGACAACCAACTGA
AGAAAGTGAAAGTTAGCCCAACCATCATGGGAACAAATATTTATATGCTTGCCCAACTTGCAAGTCAAAATTGTGGTATT
GCCTTGCTACCTGACACAGCAGCTGAGGATTTTGTAAAATCAGGTCAACTTGTACAAATCTTGCCAGATTGGAAAGCAGC
CCACGGTATATTCCATGCTGTTTATCCGTCACGAAGAGGTTTACTGCCAGCTGTACGTGTATTTATTGATTATTTGGTAG
AACATCTTTCAGAACATCCATAA

Upstream 100 bases:

>100_bases
AAGGTTTATTATAAGCTTTTTACAAAAAATTAAAATCAAACTTTATCGTTGCAAAAGTAATAATGTAAAATCTTTAGTGT
TGCATAAATAGGATATTTTA

Downstream 100 bases:

>100_bases
ATCAAAGCCGCATAAAAAAGTTCGATAGATTATCGAACTTTTTTTATGCATATTAAATTTCTGGATAATTTCCCACACCT
TCGGGCCACGGCGTTAATAA

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MLTDLDDFYCFALVVEHGGFSAAERVTDIPKSKLSRRVYNLEENLGVRLIQRSSRHFAVTDIGMDIYRHAQVMMNAAQAA
HDLVDHLSIQPRGVVKVSVPVDIAQNQLPKILPAFLKNNPEIRLQLIVSNRRVDVINEGIDIALRVRSKLDDDPSLVLRQ
FALIEQSLFASQAYLNEFGNIKSPDELSDHRILSLSEEHLDQQFILHGPDNQLKKVKVSPTIMGTNIYMLAQLASQNCGI
ALLPDTAAEDFVKSGQLVQILPDWKAAHGIFHAVYPSRRGLLPAVRVFIDYLVEHLSEHP

Sequences:

>Translated_300_residues
MLTDLDDFYCFALVVEHGGFSAAERVTDIPKSKLSRRVYNLEENLGVRLIQRSSRHFAVTDIGMDIYRHAQVMMNAAQAA
HDLVDHLSIQPRGVVKVSVPVDIAQNQLPKILPAFLKNNPEIRLQLIVSNRRVDVINEGIDIALRVRSKLDDDPSLVLRQ
FALIEQSLFASQAYLNEFGNIKSPDELSDHRILSLSEEHLDQQFILHGPDNQLKKVKVSPTIMGTNIYMLAQLASQNCGI
ALLPDTAAEDFVKSGQLVQILPDWKAAHGIFHAVYPSRRGLLPAVRVFIDYLVEHLSEHP
>Mature_300_residues
MLTDLDDFYCFALVVEHGGFSAAERVTDIPKSKLSRRVYNLEENLGVRLIQRSSRHFAVTDIGMDIYRHAQVMMNAAQAA
HDLVDHLSIQPRGVVKVSVPVDIAQNQLPKILPAFLKNNPEIRLQLIVSNRRVDVINEGIDIALRVRSKLDDDPSLVLRQ
FALIEQSLFASQAYLNEFGNIKSPDELSDHRILSLSEEHLDQQFILHGPDNQLKKVKVSPTIMGTNIYMLAQLASQNCGI
ALLPDTAAEDFVKSGQLVQILPDWKAAHGIFHAVYPSRRGLLPAVRVFIDYLVEHLSEHP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=301, Percent_Identity=28.2392026578073, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=29.0102389078498, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=26.8707482993197, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=25.6944444444444, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87081978, Length=298, Percent_Identity=27.8523489932886, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=22.0338983050847, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787589, Length=292, Percent_Identity=25, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787601, Length=128, Percent_Identity=25.78125, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33696; Mature: 33696

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDLDDFYCFALVVEHGGFSAAERVTDIPKSKLSRRVYNLEENLGVRLIQRSSRHFAVT
CCCCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCHHEEECCCCEEEEE
DIGMDIYRHAQVMMNAAQAAHDLVDHLSIQPRGVVKVSVPVDIAQNQLPKILPAFLKNNP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCC
EIRLQLIVSNRRVDVINEGIDIALRVRSKLDDDPSLVLRQFALIEQSLFASQAYLNEFGN
CEEEEEEEECCCEEEECCCCEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
IKSPDELSDHRILSLSEEHLDQQFILHGPDNQLKKVKVSPTIMGTNIYMLAQLASQNCGI
CCCCCCCCCCEEEECCHHHCCCEEEEECCCCCCEEEEECCEEECCHHHHHHHHHCCCCCE
ALLPDTAAEDFVKSGQLVQILPDWKAAHGIFHAVYPSRRGLLPAVRVFIDYLVEHLSEHP
EECCCCHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTDLDDFYCFALVVEHGGFSAAERVTDIPKSKLSRRVYNLEENLGVRLIQRSSRHFAVT
CCCCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCHHEEECCCCEEEEE
DIGMDIYRHAQVMMNAAQAAHDLVDHLSIQPRGVVKVSVPVDIAQNQLPKILPAFLKNNP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCC
EIRLQLIVSNRRVDVINEGIDIALRVRSKLDDDPSLVLRQFALIEQSLFASQAYLNEFGN
CEEEEEEEECCCEEEECCCCEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
IKSPDELSDHRILSLSEEHLDQQFILHGPDNQLKKVKVSPTIMGTNIYMLAQLASQNCGI
CCCCCCCCCCEEEECCHHHCCCEEEEECCCCCCEEEEECCEEECCHHHHHHHHHCCCCCE
ALLPDTAAEDFVKSGQLVQILPDWKAAHGIFHAVYPSRRGLLPAVRVFIDYLVEHLSEHP
EECCCCHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]