Click here to switch to the map view.

The map label for this gene is acoB [H]

Identifier: 213157242

GI number: 213157242

Start: 2015466

End: 2016485

Strand: Direct

Name: acoB [H]

Synonym: AB57_1929

Alternate gene names: 213157242

Gene position: 2015466-2016485 (Clockwise)

Preceding gene: 213157241

Following gene: 213157243

Centisome position: 49.76

GC content: 45.59

Gene sequence:

>1020_bases
ATGCCAAATAAAAGTTTTCGTAATGCAATTAAAGAAGCCATTGAATCAGAAATGCGCCGTGATCCAACCGTATTTGTTGT
TGGTGAAGATGTTCGCGGTGGACACGGCGGTAAAAATACCGAAGAGAACGAGCTTGAAGGCTTCGGTGGGGTACTTGGTG
TAACCAAAGGTTTATGGACGGAGTTTGGTTCAGAACGTGTGATTGATACACCAATTACCGAGTCTGCAATTATCGGTATG
GCCGCCGGTGCGGCTGCAACAGGTTTACGTCCTGTTGCTGATTTAATGTTTATGGACTTCTATGGCGTGTGTCATGACAT
GCTCTATAACCAAGCCGCTAAATTCCGTTATATGTTTGGCGGAAAAGCAAAAGCGCCAATGGTTGTACGTGGCATGATTG
GCGCAGGTTTTTCTGCGGCAGCCCAGCACTCTCAGTCACCATATAACGTATTTGCCGCGGTTCCGGGCTTAAAAGTTGTG
GTTCCATCTAGCCCATATGATGTGAAAGGGCTATTAATTCAGGCTATTCGTGATGACGACCCTGTAGTGTTCTGTGAACA
TAAAATGCTCTATGACATTAAGGGCGAAGTTCCAGATGATGCCTATACCATTCCTTTTGGTGTAGCAAATTACACCCGTG
AAGGGACAGATGTGACCATTATTGCTTTAGGCCTGATGGTACACCGTGCCAATGAAGTAGCGGACAAACTGGCAAAAGAT
GGTATTTCAGTTGAAGTGGTAGACCCTCGAACAATTTCGCCTCTGGATGAAGAAGGGATTTTAGAGTCTGTTGCATCGAC
TGGGCGTGTGGTTATTGTGGATGAATCAGCAGCACGCTGTGGTTTTGGTCATGATGTTGCTGCACTGATTGCCCAAAAAG
GTTTCCACTATTTGAAAGCACCTGTTGAACTCGTAACGCCACCACATACGCCTGTTCCATTCTCTCCAGTTTTAGAAAAA
GAATGGATTCCAAGTGTAGAGCGTATTGAGCAAGCTGTGCGAAAAACATTGGAGGCTTAG

Upstream 100 bases:

>100_bases
AATGTTGATGATGCCGTTGCCAAAGCTCGTGCTGCGGCTTATCCAAAACCAGAACAACTCCTTACTGACGTCTATGTCTC
TTACTAAAGGAATAGTAAAG

Downstream 100 bases:

>100_bases
GATGAGCGAAATTAAAACGCTGGAGATCCCGAAATGGGGATTATCTATGGAAGAAGGCACGATCGCCCAATGGTTGATTA
AAGAGGGTGATAGCTTTAAT

Product: acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta

Products: [dihydrolipoyllysine-residue acetyltransferase] ; $S-acetyldihydrolipoyllysine; CO2

Alternate protein names: Acetoin:DCPIP oxidoreductase-beta; Ao:DCPIP OR; TPP-dependent acetoin dehydrogenase E1 subunit beta [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MPNKSFRNAIKEAIESEMRRDPTVFVVGEDVRGGHGGKNTEENELEGFGGVLGVTKGLWTEFGSERVIDTPITESAIIGM
AAGAAATGLRPVADLMFMDFYGVCHDMLYNQAAKFRYMFGGKAKAPMVVRGMIGAGFSAAAQHSQSPYNVFAAVPGLKVV
VPSSPYDVKGLLIQAIRDDDPVVFCEHKMLYDIKGEVPDDAYTIPFGVANYTREGTDVTIIALGLMVHRANEVADKLAKD
GISVEVVDPRTISPLDEEGILESVASTGRVVIVDESAARCGFGHDVAALIAQKGFHYLKAPVELVTPPHTPVPFSPVLEK
EWIPSVERIEQAVRKTLEA

Sequences:

>Translated_339_residues
MPNKSFRNAIKEAIESEMRRDPTVFVVGEDVRGGHGGKNTEENELEGFGGVLGVTKGLWTEFGSERVIDTPITESAIIGM
AAGAAATGLRPVADLMFMDFYGVCHDMLYNQAAKFRYMFGGKAKAPMVVRGMIGAGFSAAAQHSQSPYNVFAAVPGLKVV
VPSSPYDVKGLLIQAIRDDDPVVFCEHKMLYDIKGEVPDDAYTIPFGVANYTREGTDVTIIALGLMVHRANEVADKLAKD
GISVEVVDPRTISPLDEEGILESVASTGRVVIVDESAARCGFGHDVAALIAQKGFHYLKAPVELVTPPHTPVPFSPVLEK
EWIPSVERIEQAVRKTLEA
>Mature_338_residues
PNKSFRNAIKEAIESEMRRDPTVFVVGEDVRGGHGGKNTEENELEGFGGVLGVTKGLWTEFGSERVIDTPITESAIIGMA
AGAAATGLRPVADLMFMDFYGVCHDMLYNQAAKFRYMFGGKAKAPMVVRGMIGAGFSAAAQHSQSPYNVFAAVPGLKVVV
PSSPYDVKGLLIQAIRDDDPVVFCEHKMLYDIKGEVPDDAYTIPFGVANYTREGTDVTIIALGLMVHRANEVADKLAKDG
ISVEVVDPRTISPLDEEGILESVASTGRVVIVDESAARCGFGHDVAALIAQKGFHYLKAPVELVTPPHTPVPFSPVLEKE
WIPSVERIEQAVRKTLEA

Specific function: Catalyzes the 2,6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde, in vitro. The beta subunit is probably not the catalytic subunit of the enzyme [H]

COG id: COG0022

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI156564403, Length=338, Percent_Identity=38.1656804733728, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI4557353, Length=335, Percent_Identity=36.7164179104478, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI34101272, Length=335, Percent_Identity=36.7164179104478, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI291084858, Length=338, Percent_Identity=36.094674556213, Blast_Score=204, Evalue=6e-53,
Organism=Homo sapiens, GI133778974, Length=245, Percent_Identity=28.1632653061224, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538422, Length=339, Percent_Identity=38.6430678466077, Blast_Score=225, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17506935, Length=335, Percent_Identity=38.2089552238806, Blast_Score=201, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6319698, Length=339, Percent_Identity=38.3480825958702, Blast_Score=220, Evalue=3e-58,
Organism=Drosophila melanogaster, GI21358145, Length=338, Percent_Identity=37.8698224852071, Blast_Score=215, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24650940, Length=338, Percent_Identity=37.8698224852071, Blast_Score=215, Evalue=4e-56,
Organism=Drosophila melanogaster, GI160714832, Length=330, Percent_Identity=37.8787878787879, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI160714828, Length=330, Percent_Identity=37.8787878787879, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24650943, Length=96, Percent_Identity=39.5833333333333, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24650945, Length=96, Percent_Identity=39.5833333333333, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: 1.2.4.1

Molecular weight: Translated: 36592; Mature: 36461

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNKSFRNAIKEAIESEMRRDPTVFVVGEDVRGGHGGKNTEENELEGFGGVLGVTKGLWT
CCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHH
EFGSERVIDTPITESAIIGMAAGAAATGLRPVADLMFMDFYGVCHDMLYNQAAKFRYMFG
HCCCCCEECCCCCHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
GKAKAPMVVRGMIGAGFSAAAQHSQSPYNVFAAVPGLKVVVPSSPYDVKGLLIQAIRDDD
CCCCCCEEEEHHHCCCHHHHHHCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHCCCC
PVVFCEHKMLYDIKGEVPDDAYTIPFGVANYTREGTDVTIIALGLMVHRANEVADKLAKD
CEEEECCEEEEEECCCCCCCCEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHC
GISVEVVDPRTISPLDEEGILESVASTGRVVIVDESAARCGFGHDVAALIAQKGFHYLKA
CCEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCHHHHC
PVELVTPPHTPVPFSPVLEKEWIPSVERIEQAVRKTLEA
CCEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PNKSFRNAIKEAIESEMRRDPTVFVVGEDVRGGHGGKNTEENELEGFGGVLGVTKGLWT
CCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHH
EFGSERVIDTPITESAIIGMAAGAAATGLRPVADLMFMDFYGVCHDMLYNQAAKFRYMFG
HCCCCCEECCCCCHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
GKAKAPMVVRGMIGAGFSAAAQHSQSPYNVFAAVPGLKVVVPSSPYDVKGLLIQAIRDDD
CCCCCCEEEEHHHCCCHHHHHHCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHCCCC
PVVFCEHKMLYDIKGEVPDDAYTIPFGVANYTREGTDVTIIALGLMVHRANEVADKLAKD
CEEEECCEEEEEECCCCCCCCEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHC
GISVEVVDPRTISPLDEEGILESVASTGRVVIVDESAARCGFGHDVAALIAQKGFHYLKA
CCEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCHHHHC
PVELVTPPHTPVPFSPVLEKEWIPSVERIEQAVRKTLEA
CCEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: pyruvate; [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine

Specific reaction: pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S- $acetyldihydrolipoyllysine + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2061286 [H]