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The map label for this gene is pcaI [H]

Identifier: 213156917

GI number: 213156917

Start: 1674467

End: 1675135

Strand: Direct

Name: pcaI [H]

Synonym: AB57_1588

Alternate gene names: 213156917

Gene position: 1674467-1675135 (Clockwise)

Preceding gene: 213156916

Following gene: 213156918

Centisome position: 41.34

GC content: 42.0

Gene sequence:

>669_bases
ATGATAAATAAAATCACCAGTGACATTGAACCGATTTTAAAAGCTATTCCTGATGGGGCAACCATCATGACAGGCGGGTT
TGGTGTGACGGGGCAACCTGCTGAATTAATTGAAGCCTTAATCGATTTAGGAAAAAAAGAACTCACCATTGTAAATAACA
ATGCGGCTTCTGGTGATCGTGGTTTAACAAATCTGATTATTGCCGGTTGTGTTAAAAAAATGATTTGTTCATTTCCGAAA
TCTGCTGGATCAACCGTTTTTCAAGACTTATATAGAGCGGGAAAAATTGAGTTAGAACTAGTTCCACAAGGTAATTTGGC
TTGTCGTATTCAGGCCGCAGGTGCTGGTCTCGGGGCTATTTTTACTCCGACTGGTTATGGCACTAAAGTTGCCGAGGGTA
AAGAGACCCGAACCATTAACGGTAAAAACTATGTGCTTGAATACCCACTTGAAGCTGATTTTGCACTGATTTATGCCGAT
AAAGCCGACCGTTGGGGCAATTTAACCTACCGTAAAGCAGCCCGTAATTTTGGGCCAATTATGGCAAAAGCCGCCAAGAC
CACGATTGTTCAAGTGAATGACACCGTAGAGCTAGGAACGCTTGACCCAGAGTGCATTATTACACCAGGAATTTTTGTTC
AGCACGTTGTAAAAGTAGGAGATATCTAA

Upstream 100 bases:

>100_bases
TTCCATTGTTATTTATTAAAGACCGATTATTTAACCCGCAAAAGGCAGAGTGACAGATCAATCTGTCACCTTAAATTAAG
GATGAAAAGGGACAAGTGAG

Downstream 100 bases:

>100_bases
TGTCAGTTCAAAAGCGTTCTCGTGAAGATATTGCCAAGCTCATTGCCAATGACATTCCGGAAGGTTCTTATGTCAATTTA
GGCATTGGTTTACCGACCAA

Product: 3-oxoadipate CoA-transferase subunit A

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MINKITSDIEPILKAIPDGATIMTGGFGVTGQPAELIEALIDLGKKELTIVNNNAASGDRGLTNLIIAGCVKKMICSFPK
SAGSTVFQDLYRAGKIELELVPQGNLACRIQAAGAGLGAIFTPTGYGTKVAEGKETRTINGKNYVLEYPLEADFALIYAD
KADRWGNLTYRKAARNFGPIMAKAAKTTIVQVNDTVELGTLDPECIITPGIFVQHVVKVGDI

Sequences:

>Translated_222_residues
MINKITSDIEPILKAIPDGATIMTGGFGVTGQPAELIEALIDLGKKELTIVNNNAASGDRGLTNLIIAGCVKKMICSFPK
SAGSTVFQDLYRAGKIELELVPQGNLACRIQAAGAGLGAIFTPTGYGTKVAEGKETRTINGKNYVLEYPLEADFALIYAD
KADRWGNLTYRKAARNFGPIMAKAAKTTIVQVNDTVELGTLDPECIITPGIFVQHVVKVGDI
>Mature_222_residues
MINKITSDIEPILKAIPDGATIMTGGFGVTGQPAELIEALIDLGKKELTIVNNNAASGDRGLTNLIIAGCVKKMICSFPK
SAGSTVFQDLYRAGKIELELVPQGNLACRIQAAGAGLGAIFTPTGYGTKVAEGKETRTINGKNYVLEYPLEADFALIYAD
KADRWGNLTYRKAARNFGPIMAKAAKTTIVQVNDTVELGTLDPECIITPGIFVQHVVKVGDI

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=233, Percent_Identity=43.3476394849785, Blast_Score=183, Evalue=9e-47,
Organism=Homo sapiens, GI11545841, Length=233, Percent_Identity=43.3476394849785, Blast_Score=168, Evalue=3e-42,
Organism=Escherichia coli, GI1788551, Length=204, Percent_Identity=45.0980392156863, Blast_Score=177, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17531517, Length=237, Percent_Identity=43.0379746835443, Blast_Score=175, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24655794, Length=221, Percent_Identity=42.5339366515837, Blast_Score=160, Evalue=7e-40,
Organism=Drosophila melanogaster, GI21358325, Length=221, Percent_Identity=42.5339366515837, Blast_Score=160, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 23601; Mature: 23601

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKITSDIEPILKAIPDGATIMTGGFGVTGQPAELIEALIDLGKKELTIVNNNAASGDR
CCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCC
GLTNLIIAGCVKKMICSFPKSAGSTVFQDLYRAGKIELELVPQGNLACRIQAAGAGLGAI
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCCCEE
FTPTGYGTKVAEGKETRTINGKNYVLEYPLEADFALIYADKADRWGNLTYRKAARNFGPI
ECCCCCCCCCCCCCCCEEECCCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHCCHH
MAKAAKTTIVQVNDTVELGTLDPECIITPGIFVQHVVKVGDI
HHHHHCEEEEEECCEEEECCCCCCEEECCCHHHHHHHHHCCC
>Mature Secondary Structure
MINKITSDIEPILKAIPDGATIMTGGFGVTGQPAELIEALIDLGKKELTIVNNNAASGDR
CCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCC
GLTNLIIAGCVKKMICSFPKSAGSTVFQDLYRAGKIELELVPQGNLACRIQAAGAGLGAI
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCCCEE
FTPTGYGTKVAEGKETRTINGKNYVLEYPLEADFALIYADKADRWGNLTYRKAARNFGPI
ECCCCCCCCCCCCCCCEEECCCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHCCHH
MAKAAKTTIVQVNDTVELGTLDPECIITPGIFVQHVVKVGDI
HHHHHCEEEEEECCEEEECCCCCCEEECCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8063101; 8125318 [H]