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The map label for this gene is pcm [H]

Identifier: 21244187

GI number: 21244187

Start: 4086873

End: 4087529

Strand: Direct

Name: pcm [H]

Synonym: XAC3462

Alternate gene names: 21244187

Gene position: 4086873-4087529 (Clockwise)

Preceding gene: 21244186

Following gene: 21244188

Centisome position: 78.96

GC content: 66.97

Gene sequence:

>657_bases
ATGACGATCGATTTCACCCAGGCCCGCGAAAAGATGGTCGAGCAGCAGATCCGGCCGTGGGACGTGCTGGACCTGCGCGT
ACTCGACGTGCTGGCGCGCATGCCGCGCGAAGCCTTCGTGCCGGAGGCGTACAGGACGCTGGCCTATGTCGACGTGGAAA
TTCCGCTGTCGGCCGGCCACAAGATGATGAAGCCGGTGGTCGAAGGCCGCATGTTGCAGGCACTGGATCTGCAACCAGGC
GAGGACGTCCTGGAAGTCGGCACCGGCAGCGGCTTTGCCACCGCCTGCCTGGCCGCACTGGCACGCGAAGTCCTCAGCCT
GGAGATCGACCCGGCGCTGGCCGCGGCCGCACGCGCCAATCTGGACCGCACCGGCCTGGGCAGCAACGTCCGCATCGAAA
CCGCCGACGTCTTCGGCTGGCAGAGCGAGCGTCGCTTCGACGCCATCTGCGTGACCGGTGCGGTCGACACGCTGCCCGTC
CAGTGGCTGCAGTGGTTGCGCCCGAACGGCCGGCTGTTCGTCGTGCGCGGTCACGATCCGGTGATGGAAGCGGTCCTGGT
CCGTGGCGACGTCAACGCCCCGCGCATCGAATCGTTGTTCGAAACCGACCTCGCCTATCTCCAGGGCGCCGCACCGACGC
CCCGATTCCAATTCTGA

Upstream 100 bases:

>100_bases
TCCGGCACTGCGCCGGATGCCAGCGCGCGGCGATGCTAGATGCGCCAGGTGCCTCGCGCACCGGTAAAATGTTCGCCCCA
CCGCGTTGGATACCCGCACC

Downstream 100 bases:

>100_bases
TTCCCAAGGAAGCTTCCCCGATGATCCGCCGATCCCTCGTTCTGGCCCTGGCCGCCGCCCTGTCCCCCATGGCTGCGCAC
GCCACCGACCTGCTGCAGGT

Product: L-isoaspartate protein carboxylmethyltransferase

Products: NA

Alternate protein names: L-isoaspartyl protein carboxyl methyltransferase 2; Protein L-isoaspartyl methyltransferase 2; Protein-beta-aspartate methyltransferase 2; PIMT 2 [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTIDFTQAREKMVEQQIRPWDVLDLRVLDVLARMPREAFVPEAYRTLAYVDVEIPLSAGHKMMKPVVEGRMLQALDLQPG
EDVLEVGTGSGFATACLAALAREVLSLEIDPALAAAARANLDRTGLGSNVRIETADVFGWQSERRFDAICVTGAVDTLPV
QWLQWLRPNGRLFVVRGHDPVMEAVLVRGDVNAPRIESLFETDLAYLQGAAPTPRFQF

Sequences:

>Translated_218_residues
MTIDFTQAREKMVEQQIRPWDVLDLRVLDVLARMPREAFVPEAYRTLAYVDVEIPLSAGHKMMKPVVEGRMLQALDLQPG
EDVLEVGTGSGFATACLAALAREVLSLEIDPALAAAARANLDRTGLGSNVRIETADVFGWQSERRFDAICVTGAVDTLPV
QWLQWLRPNGRLFVVRGHDPVMEAVLVRGDVNAPRIESLFETDLAYLQGAAPTPRFQF
>Mature_217_residues
TIDFTQAREKMVEQQIRPWDVLDLRVLDVLARMPREAFVPEAYRTLAYVDVEIPLSAGHKMMKPVVEGRMLQALDLQPGE
DVLEVGTGSGFATACLAALAREVLSLEIDPALAAAARANLDRTGLGSNVRIETADVFGWQSERRFDAICVTGAVDTLPVQ
WLQWLRPNGRLFVVRGHDPVMEAVLVRGDVNAPRIESLFETDLAYLQGAAPTPRFQF

Specific function: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins [H]

COG id: COG2518

COG function: function code O; Protein-L-isoaspartate carboxylmethyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789100, Length=197, Percent_Identity=35.0253807106599, Blast_Score=98, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000682 [H]

Pfam domain/function: PF01135 PCMT [H]

EC number: =2.1.1.77 [H]

Molecular weight: Translated: 24174; Mature: 24043

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDFTQAREKMVEQQIRPWDVLDLRVLDVLARMPREAFVPEAYRTLAYVDVEIPLSAGH
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHCCCHHHHEEEEEEEECCHHCCH
KMMKPVVEGRMLQALDLQPGEDVLEVGTGSGFATACLAALAREVLSLEIDPALAAAARAN
HHHHHHHHCHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
LDRTGLGSNVRIETADVFGWQSERRFDAICVTGAVDTLPVQWLQWLRPNGRLFVVRGHDP
CCCCCCCCCEEEEEHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCH
VMEAVLVRGDVNAPRIESLFETDLAYLQGAAPTPRFQF
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TIDFTQAREKMVEQQIRPWDVLDLRVLDVLARMPREAFVPEAYRTLAYVDVEIPLSAGH
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHCCCHHHHEEEEEEEECCHHCCH
KMMKPVVEGRMLQALDLQPGEDVLEVGTGSGFATACLAALAREVLSLEIDPALAAAARAN
HHHHHHHHCHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
LDRTGLGSNVRIETADVFGWQSERRFDAICVTGAVDTLPVQWLQWLRPNGRLFVVRGHDP
CCCCCCCCCEEEEEHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCH
VMEAVLVRGDVNAPRIESLFETDLAYLQGAAPTPRFQF
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA