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The map label for this gene is modA [H]

Identifier: 21244083

GI number: 21244083

Start: 3955460

End: 3956236

Strand: Direct

Name: modA [H]

Synonym: XAC3358

Alternate gene names: 21244083

Gene position: 3955460-3956236 (Clockwise)

Preceding gene: 21244082

Following gene: 21244084

Centisome position: 76.43

GC content: 65.25

Gene sequence:

>777_bases
ATGCGCATGATCGGTTTCTGGCAGCGCGCCTTGTGCGTGCTGATGCTGACGTTGCCTGTGCTGGCGAGTGCGCAGACCGC
CCCGGTGACGGTGTTTGCGGCCGCAAGCCTGAAAGAATCGATGGACGAAGCCGCCACCGCGTACGAAAAAGCGACCGGCA
CGCCGGTACGGGTGTCGTATGCAGCGAGTTCTGCGCTGGCACGCCAGATCGAACAAGGCGCACCGGCGGACGTGTTCTTT
TCGGCCGACCTGGAGTGGATGGACTATCTGCAACAGCACGGCCTGGTACTGCCCGCGCAGCGCCACAACCTGCTCGGCAA
TACGCTGGTGTTGGTTGCGCCGGCGAGCAGCAAGCTGCGCGTGGATCCACGCGCGCCCGGCGCCATCGCCAAGGCGCTTG
GCGAGAACGGGCGCCTGGCCGTTGGTCAGACCGCCAGCGTGCCGGCCGGTAAATACGCCGCCGCTGCGCTGCGCAAGCTC
GGCCAATGGGATAGCGTCAGCAACCGTCTTGCCGAATCGGAAAGTGTGCGCGCGGCATTGATGCTGGTCTCGCGTGGCGA
AGCGCCGCTGGGCATCGTGTATGGCTCGGACGCGCGCGCCGATGCCAAGGTGCGCGTGGTCGCCACCTTCCCCGACGACA
GCCATGACGCCATCGTGTATCCGGTCGCTGCATTGAAGAACAGCAACAACCCCGCCACCGCCGCATTCGTGAGCTGGCTG
GGAAGCAAGCCGGCCAAGGCGATCTTTGCGCGCCGTGGTTTTTCGCTGAAGGATTGA

Upstream 100 bases:

>100_bases
GCGCTGGGCCGGAGTGGTCCTGTAGCGCGCGCCGGCTCGCCACGCGGTGCGCATCGCGTAGCCGCTATGATCGGGGCCCT
GTCCTGGTGAGGAGCCTTCG

Downstream 100 bases:

>100_bases
GGCGCACCGTTTGTCGATGTTCACCCCGGAAGAGCTGACCGCGATCGGCTTGAGTCTCAAGGTCGCGATCGTGGCAGCGC
TCGCCAGCCTGCCGCCGGGC

Product: molybdate-binding periplasmic protein; permease

Products: ADP; phosphate; MoO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MRMIGFWQRALCVLMLTLPVLASAQTAPVTVFAAASLKESMDEAATAYEKATGTPVRVSYAASSALARQIEQGAPADVFF
SADLEWMDYLQQHGLVLPAQRHNLLGNTLVLVAPASSKLRVDPRAPGAIAKALGENGRLAVGQTASVPAGKYAAAALRKL
GQWDSVSNRLAESESVRAALMLVSRGEAPLGIVYGSDARADAKVRVVATFPDDSHDAIVYPVAALKNSNNPATAAFVSWL
GSKPAKAIFARRGFSLKD

Sequences:

>Translated_258_residues
MRMIGFWQRALCVLMLTLPVLASAQTAPVTVFAAASLKESMDEAATAYEKATGTPVRVSYAASSALARQIEQGAPADVFF
SADLEWMDYLQQHGLVLPAQRHNLLGNTLVLVAPASSKLRVDPRAPGAIAKALGENGRLAVGQTASVPAGKYAAAALRKL
GQWDSVSNRLAESESVRAALMLVSRGEAPLGIVYGSDARADAKVRVVATFPDDSHDAIVYPVAALKNSNNPATAAFVSWL
GSKPAKAIFARRGFSLKD
>Mature_258_residues
MRMIGFWQRALCVLMLTLPVLASAQTAPVTVFAAASLKESMDEAATAYEKATGTPVRVSYAASSALARQIEQGAPADVFF
SADLEWMDYLQQHGLVLPAQRHNLLGNTLVLVAPASSKLRVDPRAPGAIAKALGENGRLAVGQTASVPAGKYAAAALRKL
GQWDSVSNRLAESESVRAALMLVSRGEAPLGIVYGSDARADAKVRVVATFPDDSHDAIVYPVAALKNSNNPATAAFVSWL
GSKPAKAIFARRGFSLKD

Specific function: Involved in the transport of molybdenum into the cell. Binds molybdate with high specificity and affinity [H]

COG id: COG0725

COG function: function code P; ABC-type molybdate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein modA family [H]

Homologues:

Organism=Escherichia coli, GI1786979, Length=239, Percent_Identity=51.0460251046025, Blast_Score=219, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005950
- InterPro:   IPR006059 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 27234; Mature: 27234

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMIGFWQRALCVLMLTLPVLASAQTAPVTVFAAASLKESMDEAATAYEKATGTPVRVSY
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEH
AASSALARQIEQGAPADVFFSADLEWMDYLQQHGLVLPAQRHNLLGNTLVLVAPASSKLR
HHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCEEEEHHHCCCCCCEEEEEECCCCCEE
VDPRAPGAIAKALGENGRLAVGQTASVPAGKYAAAALRKLGQWDSVSNRLAESESVRAAL
ECCCCCHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
MLVSRGEAPLGIVYGSDARADAKVRVVATFPDDSHDAIVYPVAALKNSNNPATAAFVSWL
HEEECCCCCEEEEECCCCCCCCEEEEEEECCCCCCCEEEEEHHHHCCCCCCHHHHHHHHH
GSKPAKAIFARRGFSLKD
CCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRMIGFWQRALCVLMLTLPVLASAQTAPVTVFAAASLKESMDEAATAYEKATGTPVRVSY
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEH
AASSALARQIEQGAPADVFFSADLEWMDYLQQHGLVLPAQRHNLLGNTLVLVAPASSKLR
HHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCEEEEHHHCCCCCCEEEEEECCCCCEE
VDPRAPGAIAKALGENGRLAVGQTASVPAGKYAAAALRKLGQWDSVSNRLAESESVRAAL
ECCCCCHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
MLVSRGEAPLGIVYGSDARADAKVRVVATFPDDSHDAIVYPVAALKNSNNPATAAFVSWL
HEEECCCCCEEEEECCCCCCCCEEEEEEECCCCCCCEEEEEHHHHCCCCCCHHHHHHHHH
GSKPAKAIFARRGFSLKD
CCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; MoO42- [Periplasm]; H2O [C]

Specific reaction: ATP + MoO42- [Periplasm] + H2O = ADP + phosphate + MoO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7860583; 8564363; 8905232; 9278503; 8576221; 9302996 [H]