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The map label for this gene is aspA [H]

Identifier: 21243560

GI number: 21243560

Start: 3322511

End: 3324244

Strand: Direct

Name: aspA [H]

Synonym: XAC2833

Alternate gene names: 21243560

Gene position: 3322511-3324244 (Clockwise)

Preceding gene: 21243559

Following gene: 21243561

Centisome position: 64.2

GC content: 61.65

Gene sequence:

>1734_bases
ATGCTGCGGCAACCGGTGTCGATGCATCGATCAGGACGACGCAGAACACACGCAATGCCAGCGACCCGTTGTTCCGCTAC
CAATGGCATCCAAGGCCAGCCGGTGTTCGGCGACCAACGTCCGCGGCCAGGCGTCGATCTGGATGTGGACATCCTGCACA
CGCTCGGCATTCGCGGAGCCGGAGTCAAGGTGGCGGTCATCGATGATGGGCTCGAGATTGCGCATGAGGATCTCGTCGAC
AACATCGTTGCCGGCGGCTCGCATAACTTCTTGAATGGTTCCAACGATCCGACGCCGCCTGCGGACGAAATCGACAATGA
CCACGGCACCGCGGTCGCCGGCATCATCGCGGCACGTGGATGGAATGGTCTGGGTGGACGCGGTGTTGCACCAGAGGCGA
ATGTGGCTGGCTTCAACGCACTTTCCATACTCGATGGCAGCAAGCAATACGTGGATATCCGTTACTCCTGGGGCGATGGC
GCAGAAGCCCGTGCGATGGACGTGTACAACAACAGCTTCGGCATCTCGACAGCGGTCTATCCATTCAGCGATCTCGACGA
GCAGCGCTCTCTGGAGAAACTGATGCGTGCCCAGCGTGGTGGCAAGGGCGGCATCTACGTCAAGGCAGCTGGCAATGATT
TCAATACGCTGCTCGATGTGGATGCACAGGGCAAGCTGATCGATCGTTGCAGCGACCAGACCCGGCAACTCGGCGTCGCC
TGCAGCAGCGCCAATATCGACAACCTCAACAGTCTGACCACCATGATCGTGGTGGGTGCGGTCAACGCCAACGGCGTGCG
TGCGAGCTATTCATCGCCCGGATCCGCGTTGTGGGTGTCCGGTCTCTCCGGCGAATTTGGGTTCCAGCGTCGCTTCGACC
CGCATCCTGAGACTTACAGTCCGTTGTATACACTGCTCGCTGCGCAGGGCCCGCAACCATTCTTCTCACCGGCGATCGTC
ACGACCGACCTGAGTGGATGCGCTGCAGGCAATAATCGCGATCGGACGCGCGCGCCGCAGAATGCGCTGGATACCAGCCA
CTCCAAAATCGATGCCTCGTGCAACTACAGCGCACGCATGAATGGCACCTCCGCCTCCGCACCAACGGTTGCAGGCGTCG
CGGCGCTGATGCTGGGCGCCAACCCGCAGCTGACGCTGCGCGATGTCAAATACATCCTGGCAACGACGGCGGTGCAGGTC
GATCCCCATCAGGCCAAGGCGTTCTACAAGGACGCCGTGATCGAGCCCGCCTGGATCACCAACGCGGCCGGCCACCGTTT
CAGCAACTGGTATGGCTTCGGTTTGGTGGATGCAGCCGCGGCGGTGGAGCGTGCGATGCATTTCACTCCGCTGCCGGCGA
TGCAAGACACCGAGTGGACCGTCTATGACGGCGAGAGCAGCACCATCGGCGGTATCGGCTCGCCCGCGCGATTAGCGATC
GACATCAAGCAGTCCTTCAAGGTGGAAGGCGTACAGCTGTACTTCGCAGGGACGCACAAGCATCCTCGCCAACTGCGCGC
CGTGCTGGTATCGCCCAGCGGCACCCGCAGCACCGTGATGACGCCGTTCTCCACGCTCGACCCGGGTGATGGCTTCGTGG
TCTTCCTGACCTCCAGCAATGCCTTCCTGGACGAGGCGGCAGCCGGTCGCTGGACACTGGAGGTGGACGACATGCTCGCC
GACAACGGCAAGGAACAACTGCAGGAATTCGAAATGCGCGTGGTGGGCCACTGA

Upstream 100 bases:

>100_bases
CCCCATTACCGATACCATCCCATGACAACCTCTCCCCTGCGGCGATTGCCGCTGCTGTGCGCGTGCCTACTGGCGCTCGG
ACCCTTCTCGCTGACCGCCG

Downstream 100 bases:

>100_bases
CATGAAAACTTCTCTGATCACACTGCTGTGCGTCGTTGCCGCCAGCATGTCTGCACCCGTCTCGGCACAGGTGTTCGATC
GCGCCCGCCTGCGTGCTGCC

Product: extracellular serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MLRQPVSMHRSGRRRTHAMPATRCSATNGIQGQPVFGDQRPRPGVDLDVDILHTLGIRGAGVKVAVIDDGLEIAHEDLVD
NIVAGGSHNFLNGSNDPTPPADEIDNDHGTAVAGIIAARGWNGLGGRGVAPEANVAGFNALSILDGSKQYVDIRYSWGDG
AEARAMDVYNNSFGISTAVYPFSDLDEQRSLEKLMRAQRGGKGGIYVKAAGNDFNTLLDVDAQGKLIDRCSDQTRQLGVA
CSSANIDNLNSLTTMIVVGAVNANGVRASYSSPGSALWVSGLSGEFGFQRRFDPHPETYSPLYTLLAAQGPQPFFSPAIV
TTDLSGCAAGNNRDRTRAPQNALDTSHSKIDASCNYSARMNGTSASAPTVAGVAALMLGANPQLTLRDVKYILATTAVQV
DPHQAKAFYKDAVIEPAWITNAAGHRFSNWYGFGLVDAAAAVERAMHFTPLPAMQDTEWTVYDGESSTIGGIGSPARLAI
DIKQSFKVEGVQLYFAGTHKHPRQLRAVLVSPSGTRSTVMTPFSTLDPGDGFVVFLTSSNAFLDEAAAGRWTLEVDDMLA
DNGKEQLQEFEMRVVGH

Sequences:

>Translated_577_residues
MLRQPVSMHRSGRRRTHAMPATRCSATNGIQGQPVFGDQRPRPGVDLDVDILHTLGIRGAGVKVAVIDDGLEIAHEDLVD
NIVAGGSHNFLNGSNDPTPPADEIDNDHGTAVAGIIAARGWNGLGGRGVAPEANVAGFNALSILDGSKQYVDIRYSWGDG
AEARAMDVYNNSFGISTAVYPFSDLDEQRSLEKLMRAQRGGKGGIYVKAAGNDFNTLLDVDAQGKLIDRCSDQTRQLGVA
CSSANIDNLNSLTTMIVVGAVNANGVRASYSSPGSALWVSGLSGEFGFQRRFDPHPETYSPLYTLLAAQGPQPFFSPAIV
TTDLSGCAAGNNRDRTRAPQNALDTSHSKIDASCNYSARMNGTSASAPTVAGVAALMLGANPQLTLRDVKYILATTAVQV
DPHQAKAFYKDAVIEPAWITNAAGHRFSNWYGFGLVDAAAAVERAMHFTPLPAMQDTEWTVYDGESSTIGGIGSPARLAI
DIKQSFKVEGVQLYFAGTHKHPRQLRAVLVSPSGTRSTVMTPFSTLDPGDGFVVFLTSSNAFLDEAAAGRWTLEVDDMLA
DNGKEQLQEFEMRVVGH
>Mature_577_residues
MLRQPVSMHRSGRRRTHAMPATRCSATNGIQGQPVFGDQRPRPGVDLDVDILHTLGIRGAGVKVAVIDDGLEIAHEDLVD
NIVAGGSHNFLNGSNDPTPPADEIDNDHGTAVAGIIAARGWNGLGGRGVAPEANVAGFNALSILDGSKQYVDIRYSWGDG
AEARAMDVYNNSFGISTAVYPFSDLDEQRSLEKLMRAQRGGKGGIYVKAAGNDFNTLLDVDAQGKLIDRCSDQTRQLGVA
CSSANIDNLNSLTTMIVVGAVNANGVRASYSSPGSALWVSGLSGEFGFQRRFDPHPETYSPLYTLLAAQGPQPFFSPAIV
TTDLSGCAAGNNRDRTRAPQNALDTSHSKIDASCNYSARMNGTSASAPTVAGVAALMLGANPQLTLRDVKYILATTAVQV
DPHQAKAFYKDAVIEPAWITNAAGHRFSNWYGFGLVDAAAAVERAMHFTPLPAMQDTEWTVYDGESSTIGGIGSPARLAI
DIKQSFKVEGVQLYFAGTHKHPRQLRAVLVSPSGTRSTVMTPFSTLDPGDGFVVFLTSSNAFLDEAAAGRWTLEVDDMLA
DNGKEQLQEFEMRVVGH

Specific function: Agent of furonculosis [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4505577, Length=556, Percent_Identity=27.3381294964029, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI20336180, Length=556, Percent_Identity=27.3381294964029, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI20336184, Length=556, Percent_Identity=27.6978417266187, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI20336182, Length=556, Percent_Identity=27.6978417266187, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI27894285, Length=540, Percent_Identity=27.037037037037, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI20336190, Length=540, Percent_Identity=27.037037037037, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI20336188, Length=540, Percent_Identity=27.037037037037, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI4505579, Length=571, Percent_Identity=26.0945709281961, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI20336244, Length=550, Percent_Identity=26.7272727272727, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI76443679, Length=532, Percent_Identity=26.5037593984962, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI20336242, Length=536, Percent_Identity=26.4925373134328, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI295424143, Length=536, Percent_Identity=26.4925373134328, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI20336248, Length=507, Percent_Identity=24.65483234714, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI299523015, Length=324, Percent_Identity=29.6296296296296, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI20336246, Length=324, Percent_Identity=29.6296296296296, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI295424145, Length=207, Percent_Identity=31.4009661835749, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI25141268, Length=557, Percent_Identity=28.7253141831239, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71988321, Length=535, Percent_Identity=25.7943925233645, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71988297, Length=535, Percent_Identity=25.7943925233645, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71988315, Length=535, Percent_Identity=25.7943925233645, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71988301, Length=532, Percent_Identity=25, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71988308, Length=532, Percent_Identity=24.4360902255639, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71988312, Length=529, Percent_Identity=25.1417769376182, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71983555, Length=414, Percent_Identity=28.5024154589372, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71987206, Length=563, Percent_Identity=26.2877442273535, Blast_Score=99, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6324091, Length=250, Percent_Identity=32.8, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24642494, Length=544, Percent_Identity=27.2058823529412, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24642490, Length=544, Percent_Identity=27.2058823529412, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI45555723, Length=544, Percent_Identity=27.2058823529412, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24642492, Length=544, Percent_Identity=27.2058823529412, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281360987, Length=544, Percent_Identity=27.2058823529412, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24642488, Length=531, Percent_Identity=27.3069679849341, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24642484, Length=531, Percent_Identity=27.3069679849341, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24642486, Length=531, Percent_Identity=27.3069679849341, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17136192, Length=525, Percent_Identity=27.2380952380952, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17864552, Length=225, Percent_Identity=30.6666666666667, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24650056, Length=204, Percent_Identity=31.8627450980392, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24650058, Length=211, Percent_Identity=30.8056872037915, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24650060, Length=211, Percent_Identity=30.8056872037915, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45553513, Length=211, Percent_Identity=30.8056872037915, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45553515, Length=211, Percent_Identity=30.8056872037915, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281360985, Length=193, Percent_Identity=31.6062176165803, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR002884 [H]

Pfam domain/function: PF01483 P_proprotein; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 61530; Mature: 61530

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRQPVSMHRSGRRRTHAMPATRCSATNGIQGQPVFGDQRPRPGVDLDVDILHTLGIRGA
CCCCCHHHHHCCCCHHCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCC
GVKVAVIDDGLEIAHEDLVDNIVAGGSHNFLNGSNDPTPPADEIDNDHGTAVAGIIAARG
CEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEHEECC
WNGLGGRGVAPEANVAGFNALSILDGSKQYVDIRYSWGDGAEARAMDVYNNSFGISTAVY
CCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCEEEEEECCCCCCEEEEC
PFSDLDEQRSLEKLMRAQRGGKGGIYVKAAGNDFNTLLDVDAQGKLIDRCSDQTRQLGVA
CCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHEEE
CSSANIDNLNSLTTMIVVGAVNANGVRASYSSPGSALWVSGLSGEFGFQRRFDPHPETYS
ECCCCCCCHHHEEEEEEEECCCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCHH
PLYTLLAAQGPQPFFSPAIVTTDLSGCAAGNNRDRTRAPQNALDTSHSKIDASCNYSARM
HHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCEECCCCCCEEEE
NGTSASAPTVAGVAALMLGANPQLTLRDVKYILATTAVQVDPHQAKAFYKDAVIEPAWIT
CCCCCCCCHHHHHHHHHHCCCCCEEHHHHHEEHHHEEEEECHHHHHHHHHHHCCCCHHCC
NAAGHRFSNWYGFGLVDAAAAVERAMHFTPLPAMQDTEWTVYDGESSTIGGIGSPARLAI
CCCCCCCCCEECCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEE
DIKQSFKVEGVQLYFAGTHKHPRQLRAVLVSPSGTRSTVMTPFSTLDPGDGFVVFLTSSN
EECCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCEEEEEECCC
AFLDEAAAGRWTLEVDDMLADNGKEQLQEFEMRVVGH
CHHHHHCCCEEEEEEHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLRQPVSMHRSGRRRTHAMPATRCSATNGIQGQPVFGDQRPRPGVDLDVDILHTLGIRGA
CCCCCHHHHHCCCCHHCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCC
GVKVAVIDDGLEIAHEDLVDNIVAGGSHNFLNGSNDPTPPADEIDNDHGTAVAGIIAARG
CEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEHEECC
WNGLGGRGVAPEANVAGFNALSILDGSKQYVDIRYSWGDGAEARAMDVYNNSFGISTAVY
CCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCEEEEEECCCCCCEEEEC
PFSDLDEQRSLEKLMRAQRGGKGGIYVKAAGNDFNTLLDVDAQGKLIDRCSDQTRQLGVA
CCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHEEE
CSSANIDNLNSLTTMIVVGAVNANGVRASYSSPGSALWVSGLSGEFGFQRRFDPHPETYS
ECCCCCCCHHHEEEEEEEECCCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCHH
PLYTLLAAQGPQPFFSPAIVTTDLSGCAAGNNRDRTRAPQNALDTSHSKIDASCNYSARM
HHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCEECCCCCCEEEE
NGTSASAPTVAGVAALMLGANPQLTLRDVKYILATTAVQVDPHQAKAFYKDAVIEPAWIT
CCCCCCCCHHHHHHHHHHCCCCCEEHHHHHEEHHHEEEEECHHHHHHHHHHHCCCCHHCC
NAAGHRFSNWYGFGLVDAAAAVERAMHFTPLPAMQDTEWTVYDGESSTIGGIGSPARLAI
CCCCCCCCCEECCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEE
DIKQSFKVEGVQLYFAGTHKHPRQLRAVLVSPSGTRSTVMTPFSTLDPGDGFVVFLTSSN
EECCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCEEEEEECCC
AFLDEAAAGRWTLEVDDMLADNGKEQLQEFEMRVVGH
CHHHHHCCCEEEEEEHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1468618 [H]