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The map label for this gene is lrp [C]

Identifier: 21243248

GI number: 21243248

Start: 2944665

End: 2945105

Strand: Reverse

Name: lrp [C]

Synonym: XAC2515

Alternate gene names: 21243248

Gene position: 2945105-2944665 (Counterclockwise)

Preceding gene: 77748660

Following gene: 21243247

Centisome position: 56.9

GC content: 66.21

Gene sequence:

>441_bases
ATGCGCAATGTGAAGATCACCCCGTCCGACGAACGCCTGTTATCGCTGCTGCGCGAGGACGCACGCGCCTCCACCGCCCA
GATCGCGCGGCGGCTCGGGCTCTCGCGCACGACCGTGCAGAGCCGCATCGAAAAGCTCGAACGCGACGGCGTGATCAGCG
GCTACACCGTGCGCACGCATGACCACTACGAGCAGGGCCGCATCCGCGCGCACATCCTGATCACCGTGCTGCCCAAGAAA
ATGCCTGCCGTGGTGAAGGCCCTGCGCGATATTCCGGAAGTGCGCCTGCTGCATTCGGTCAGCGGTGCCTACGACCTGGT
CGCCCTGGGGGTGGTCGGCGGCGTCAACGAGATGGACGTGCTCACCGACGCCATCGGCGCCATCGACGGCGTGGAGCGCA
CGACCAGCGCGATCATCCTGTCGACCAAATTCGAGCGGTGA

Upstream 100 bases:

>100_bases
TCAAAGGTGGCGTTCCCTTCCTATTATCGGCAGAAGATCGGCGTTTGGCAGCGTGAATCTGGGCAAGAAGTACGATATTT
TCGGCGATTCGCCGAAACGA

Downstream 100 bases:

>100_bases
ATGGAGAATCGGGAATAGGGAATCGGAAGCGCTGCCGCCCGTCCGATTCCCCAGTCCCAATTCTCGATTCCCGGCCGCAG
TTACACTATGCGGCTACCCA

Product: AsnC/Lrp family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MRNVKITPSDERLLSLLREDARASTAQIARRLGLSRTTVQSRIEKLERDGVISGYTVRTHDHYEQGRIRAHILITVLPKK
MPAVVKALRDIPEVRLLHSVSGAYDLVALGVVGGVNEMDVLTDAIGAIDGVERTTSAIILSTKFER

Sequences:

>Translated_146_residues
MRNVKITPSDERLLSLLREDARASTAQIARRLGLSRTTVQSRIEKLERDGVISGYTVRTHDHYEQGRIRAHILITVLPKK
MPAVVKALRDIPEVRLLHSVSGAYDLVALGVVGGVNEMDVLTDAIGAIDGVERTTSAIILSTKFER
>Mature_146_residues
MRNVKITPSDERLLSLLREDARASTAQIARRLGLSRTTVQSRIEKLERDGVISGYTVRTHDHYEQGRIRAHILITVLPKK
MPAVVKALRDIPEVRLLHSVSGAYDLVALGVVGGVNEMDVLTDAIGAIDGVERTTSAIILSTKFER

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=102, Percent_Identity=33.3333333333333, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR013249
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 16126; Mature: 16126

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNVKITPSDERLLSLLREDARASTAQIARRLGLSRTTVQSRIEKLERDGVISGYTVRTH
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECC
DHYEQGRIRAHILITVLPKKMPAVVKALRDIPEVRLLHSVSGAYDLVALGVVGGVNEMDV
CCHHCCCEEEEEEEEECCCHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHCCCCHHHH
LTDAIGAIDGVERTTSAIILSTKFER
HHHHHHHHCCHHHHHHEEEEEECCCC
>Mature Secondary Structure
MRNVKITPSDERLLSLLREDARASTAQIARRLGLSRTTVQSRIEKLERDGVISGYTVRTH
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECC
DHYEQGRIRAHILITVLPKKMPAVVKALRDIPEVRLLHSVSGAYDLVALGVVGGVNEMDV
CCHHCCCEEEEEEEEECCCHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHCCCCHHHH
LTDAIGAIDGVERTTSAIILSTKFER
HHHHHHHHCCHHHHHHEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]