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The map label for this gene is yhdG [H]

Identifier: 21242585

GI number: 21242585

Start: 2136176

End: 2137606

Strand: Reverse

Name: yhdG [H]

Synonym: XAC1841

Alternate gene names: 21242585

Gene position: 2137606-2136176 (Counterclockwise)

Preceding gene: 21242586

Following gene: 21242584

Centisome position: 41.3

GC content: 65.69

Gene sequence:

>1431_bases
ATGTTCAAACAACTTTGGGCCACCAAACACCCGCACGCCAGCCATGAGGCGGCCGATGGGCTGGGCCTGCAACGCGCGCT
TGGCCCCTGGGGGCTGACCGCCCTGGGGATTGGGGCGGTGATCGGCGGCGGCATCTTCGTCATCACCGGCCAAGCGGCGG
CCGACCATGCCGGCCCGGCGATCATGCTCTCGTTCGTGCTCGCAGCGGTGTGCTGTGCGTTCTGTGCGATGGCCTACGCC
GAATTCGCTGCGATGGTGCCGGTCTCCGGCAGCGCCTACACCTACACCTACGCCACCTTCGGCGAGTTGGCCGCGTGGTT
CATCGGCTGGATGCTGGTGCTGGAATACGGCGTGTCCGCCTCGGCAGTGGCGGTCAGCTGGACCGGCTACTTCTTGAGCC
TGCTCGAGCATTTCGACATCCATCTGCCGGCCGCATTCGTCAGCGCGCCGCTGGACGGCAAATTGCAACCCACCGGGGCG
ATCGCCAACCTGCCGGCGGCCGGCATCGTGCTGCTGCTGACCTGGCTGTGCTATGTCGGCATCCGCAAGTCGTCGGCAAT
GAACATGGCCATGGTGATCCTCAAGACCGGCCTGATCCTGCTGGTGATCGCGGTGGGCTGGAAATACGTGGACACCTCCA
ACTGGCACCCGTTCATTCCGGCCAACGAAGGCCCGGGCAAATACGGCATGGAAGGCGTGCTGCGCGGCGCAGCGATGGTG
TTCTTCGCCTATATCGGCTTCGAAGCGGTGTCGGTGGCAGCGCAGGAATCGCATCGCCCGCAACGCGACCTGCCGATCGG
CATGATCCTGTCGCTGGTGATCTGCACCGTGCTCTACATCGCCATGGCGGCGGTCATGACCGGCTTGGTGCCGTACACCT
TGCTCGGCACCGACGAGCCGGTGGTGACCGCGGTGGCAGCGCATCCGCAGCTGGCCTGGTTGCGCGTGGTCGTGGAAGTG
GGCGCGTTGATCGGGCTGTCGTCGGTGGTGCTGGTGATGATCATCGGGCAGCCGCGCATCTTCATGATCATTGCGCGCGA
TGGCCTGCTGCCCTCGATCTTCACCCGCATCCATCCCAAGTACCGCACCCCGCATGTCAATACCGTCATCACCGGTGTCG
GCATCGCGCTGCTGGCAGCGGTGTTCCCGCTGGATGTGCTGGGCGAACTGACGTCGATGGGCACGCTGATCGCCTTCGCG
GCGGTCTGCGCCGGCGTGCTGATCCTGCGTCGCACGCACCCGGAACTGCCGCGTCCGTTCCGCATGCCGGCCGCCTGGCT
GATCTGCACCGCCGGCGTGTTGAGCTGCCTTGCGCTGCTGTCGGCAATGACGCTGCACAACTGGATGCTGATGGGCCTGT
GGACGCTGGTCGGGCTGGTGATCTACTTCGGCTACGGGTATCGCCACAGCCGTCTGCGCGACGGCCGCTGA

Upstream 100 bases:

>100_bases
AGTCGCCTCGCGAAACGGGCCTAACCTTCTCTCAAGACCGGCGCGCGACGCCGGTCTTCTTGTTCAATGATCGCGCGTAG
CGCCAAGCCGGAACCGCTTC

Downstream 100 bases:

>100_bases
GCCCACGCATGATCCGGCGTCGGGCGCGGCAGGACGACGCCTGCTGCGCTGCACCTGCCCATGCACCGGGGGCGCAGTAG
AATAGGTCCATGAATGCGAC

Product: cationic amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MFKQLWATKHPHASHEAADGLGLQRALGPWGLTALGIGAVIGGGIFVITGQAAADHAGPAIMLSFVLAAVCCAFCAMAYA
EFAAMVPVSGSAYTYTYATFGELAAWFIGWMLVLEYGVSASAVAVSWTGYFLSLLEHFDIHLPAAFVSAPLDGKLQPTGA
IANLPAAGIVLLLTWLCYVGIRKSSAMNMAMVILKTGLILLVIAVGWKYVDTSNWHPFIPANEGPGKYGMEGVLRGAAMV
FFAYIGFEAVSVAAQESHRPQRDLPIGMILSLVICTVLYIAMAAVMTGLVPYTLLGTDEPVVTAVAAHPQLAWLRVVVEV
GALIGLSSVVLVMIIGQPRIFMIIARDGLLPSIFTRIHPKYRTPHVNTVITGVGIALLAAVFPLDVLGELTSMGTLIAFA
AVCAGVLILRRTHPELPRPFRMPAAWLICTAGVLSCLALLSAMTLHNWMLMGLWTLVGLVIYFGYGYRHSRLRDGR

Sequences:

>Translated_476_residues
MFKQLWATKHPHASHEAADGLGLQRALGPWGLTALGIGAVIGGGIFVITGQAAADHAGPAIMLSFVLAAVCCAFCAMAYA
EFAAMVPVSGSAYTYTYATFGELAAWFIGWMLVLEYGVSASAVAVSWTGYFLSLLEHFDIHLPAAFVSAPLDGKLQPTGA
IANLPAAGIVLLLTWLCYVGIRKSSAMNMAMVILKTGLILLVIAVGWKYVDTSNWHPFIPANEGPGKYGMEGVLRGAAMV
FFAYIGFEAVSVAAQESHRPQRDLPIGMILSLVICTVLYIAMAAVMTGLVPYTLLGTDEPVVTAVAAHPQLAWLRVVVEV
GALIGLSSVVLVMIIGQPRIFMIIARDGLLPSIFTRIHPKYRTPHVNTVITGVGIALLAAVFPLDVLGELTSMGTLIAFA
AVCAGVLILRRTHPELPRPFRMPAAWLICTAGVLSCLALLSAMTLHNWMLMGLWTLVGLVIYFGYGYRHSRLRDGR
>Mature_476_residues
MFKQLWATKHPHASHEAADGLGLQRALGPWGLTALGIGAVIGGGIFVITGQAAADHAGPAIMLSFVLAAVCCAFCAMAYA
EFAAMVPVSGSAYTYTYATFGELAAWFIGWMLVLEYGVSASAVAVSWTGYFLSLLEHFDIHLPAAFVSAPLDGKLQPTGA
IANLPAAGIVLLLTWLCYVGIRKSSAMNMAMVILKTGLILLVIAVGWKYVDTSNWHPFIPANEGPGKYGMEGVLRGAAMV
FFAYIGFEAVSVAAQESHRPQRDLPIGMILSLVICTVLYIAMAAVMTGLVPYTLLGTDEPVVTAVAAHPQLAWLRVVVEV
GALIGLSSVVLVMIIGQPRIFMIIARDGLLPSIFTRIHPKYRTPHVNTVITGVGIALLAAVFPLDVLGELTSMGTLIAFA
AVCAGVLILRRTHPELPRPFRMPAAWLICTAGVLSCLALLSAMTLHNWMLMGLWTLVGLVIYFGYGYRHSRLRDGR

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258614005, Length=422, Percent_Identity=34.1232227488152, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI258614003, Length=422, Percent_Identity=34.1232227488152, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI114326544, Length=414, Percent_Identity=34.5410628019324, Blast_Score=212, Evalue=8e-55,
Organism=Homo sapiens, GI114326550, Length=414, Percent_Identity=34.5410628019324, Blast_Score=212, Evalue=8e-55,
Organism=Homo sapiens, GI258645169, Length=422, Percent_Identity=34.3601895734597, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI4507047, Length=443, Percent_Identity=31.1512415349887, Blast_Score=209, Evalue=6e-54,
Organism=Homo sapiens, GI110347453, Length=389, Percent_Identity=34.1902313624679, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI181337167, Length=396, Percent_Identity=33.3333333333333, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI71979932, Length=452, Percent_Identity=27.6548672566372, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI33286428, Length=433, Percent_Identity=25.1732101616628, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI115648063, Length=460, Percent_Identity=22.6086956521739, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI115648022, Length=460, Percent_Identity=22.6086956521739, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI186910308, Length=424, Percent_Identity=24.2924528301887, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI186910306, Length=424, Percent_Identity=24.2924528301887, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI186910304, Length=424, Percent_Identity=24.2924528301887, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI187423910, Length=463, Percent_Identity=21.1663066954644, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI7657591, Length=463, Percent_Identity=21.1663066954644, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI7657683, Length=368, Percent_Identity=23.0978260869565, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI71999149, Length=426, Percent_Identity=23.2394366197183, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082250, Length=426, Percent_Identity=25.1173708920188, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87081869, Length=411, Percent_Identity=23.1143552311436, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786694, Length=403, Percent_Identity=24.317617866005, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788480, Length=387, Percent_Identity=24.2894056847545, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081915, Length=453, Percent_Identity=23.6203090507726, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=389, Percent_Identity=35.73264781491, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17531343, Length=422, Percent_Identity=33.6492890995261, Blast_Score=208, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI17533459, Length=395, Percent_Identity=34.6835443037975, Blast_Score=204, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI17540018, Length=451, Percent_Identity=24.8337028824834, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17568033, Length=427, Percent_Identity=23.6533957845433, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71982612, Length=428, Percent_Identity=22.6635514018692, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71982608, Length=428, Percent_Identity=22.6635514018692, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32566699, Length=382, Percent_Identity=24.3455497382199, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71982623, Length=263, Percent_Identity=22.4334600760456, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221512776, Length=417, Percent_Identity=33.8129496402878, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24666159, Length=417, Percent_Identity=33.8129496402878, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24667468, Length=410, Percent_Identity=35.3658536585366, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24668806, Length=424, Percent_Identity=32.0754716981132, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI21356285, Length=424, Percent_Identity=32.0754716981132, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI24668802, Length=424, Percent_Identity=32.0754716981132, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI281366235, Length=415, Percent_Identity=32.5301204819277, Blast_Score=194, Evalue=9e-50,
Organism=Drosophila melanogaster, GI116007820, Length=415, Percent_Identity=32.5301204819277, Blast_Score=194, Evalue=9e-50,
Organism=Drosophila melanogaster, GI116007818, Length=415, Percent_Identity=32.5301204819277, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI85725152, Length=415, Percent_Identity=32.5301204819277, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI161077963, Length=410, Percent_Identity=32.9268292682927, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI221331183, Length=441, Percent_Identity=24.4897959183673, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17647653, Length=441, Percent_Identity=24.4897959183673, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24664379, Length=441, Percent_Identity=24.4897959183673, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI45550968, Length=467, Percent_Identity=22.0556745182013, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI19921172, Length=467, Percent_Identity=22.0556745182013, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21357367, Length=422, Percent_Identity=25.5924170616114, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24651635, Length=408, Percent_Identity=24.5098039215686, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24651633, Length=408, Percent_Identity=24.5098039215686, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50867; Mature: 50867

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKQLWATKHPHASHEAADGLGLQRALGPWGLTALGIGAVIGGGIFVITGQAAADHAGPA
CCHHHHCCCCCCCCCHHHCCCCHHHHCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHH
IMLSFVLAAVCCAFCAMAYAEFAAMVPVSGSAYTYTYATFGELAAWFIGWMLVLEYGVSA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCC
SAVAVSWTGYFLSLLEHFDIHLPAAFVSAPLDGKLQPTGAIANLPAAGIVLLLTWLCYVG
CCEEEEHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHH
IRKSSAMNMAMVILKTGLILLVIAVGWKYVDTSNWHPFIPANEGPGKYGMEGVLRGAAMV
CCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
FFAYIGFEAVSVAAQESHRPQRDLPIGMILSLVICTVLYIAMAAVMTGLVPYTLLGTDEP
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCC
VVTAVAAHPQLAWLRVVVEVGALIGLSSVVLVMIIGQPRIFMIIARDGLLPSIFTRIHPK
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCCCHHHHHHHCCCC
YRTPHVNTVITGVGIALLAAVFPLDVLGELTSMGTLIAFAAVCAGVLILRRTHPELPRPF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RMPAAWLICTAGVLSCLALLSAMTLHNWMLMGLWTLVGLVIYFGYGYRHSRLRDGR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MFKQLWATKHPHASHEAADGLGLQRALGPWGLTALGIGAVIGGGIFVITGQAAADHAGPA
CCHHHHCCCCCCCCCHHHCCCCHHHHCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHH
IMLSFVLAAVCCAFCAMAYAEFAAMVPVSGSAYTYTYATFGELAAWFIGWMLVLEYGVSA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCC
SAVAVSWTGYFLSLLEHFDIHLPAAFVSAPLDGKLQPTGAIANLPAAGIVLLLTWLCYVG
CCEEEEHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHH
IRKSSAMNMAMVILKTGLILLVIAVGWKYVDTSNWHPFIPANEGPGKYGMEGVLRGAAMV
CCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
FFAYIGFEAVSVAAQESHRPQRDLPIGMILSLVICTVLYIAMAAVMTGLVPYTLLGTDEP
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCC
VVTAVAAHPQLAWLRVVVEVGALIGLSSVVLVMIIGQPRIFMIIARDGLLPSIFTRIHPK
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCCCHHHHHHHCCCC
YRTPHVNTVITGVGIALLAAVFPLDVLGELTSMGTLIAFAAVCAGVLILRRTHPELPRPF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RMPAAWLICTAGVLSCLALLSAMTLHNWMLMGLWTLVGLVIYFGYGYRHSRLRDGR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]