Definition Xanthomonas axonopodis pv. citri str. 306 chromosome, complete genome.
Accession NC_003919
Length 5,175,554

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The map label for this gene is aroA

Identifier: 21242400

GI number: 21242400

Start: 1901825

End: 1903147

Strand: Direct

Name: aroA

Synonym: XAC1650

Alternate gene names: 21242400

Gene position: 1901825-1903147 (Clockwise)

Preceding gene: 21242399

Following gene: 21242403

Centisome position: 36.75

GC content: 66.74

Gene sequence:

>1323_bases
ATGAGCAGCAGCACGCACCACTGGATTGCCCGACGCGGCACCGCACTGCAGGGCAGCCTGGCCATTCCTGGCGACAAGTC
GGTTTCGCACCGCGCGGTCATGTTCGCCGCGCTCGCCGACGGCGTTTCGCAGATCGATGGGTTTCTTGAAGGCGAGGACA
CGCGCTCTACCGCCGCCATTTTCGCCAAGCTGGGCGTGCGCATCGAAACGCCGTCGGCGTCGCAGCGCATCGTGCACGGT
GTGGGTGTAGATGGTCTGCAGCCGCCAACCGAGGTGCTGGATTGCGGCAATGCCGGCACCGGGATGCGTCTGCTGGCCGG
CCTGTTGGCTGCGCAGCGCTTCGACAGCGTATTGGTGGGCGATGCGTCGTTATCCAAGCGGCCGATGCGGCGCGTGACCG
GCCCGCTGGCGCAGATGGGCGCGCGGATCGAGACGCAGGACGACGGCACGCCGCCACTGCACGTACGCGGTGGGCAGGCG
CTGCACGGCATCGATTTCGTCTCGCCGGTTGCCAGCGCGCAGGTCAAGTCTGCGGTGCTGCTGGCCGGTCTCTATGCGCA
GGGCGAGACTTCGGTGACCGAGCCGCATCCCACCCGCGACTACACCGAGCGCATGCTGTCGGCGTTCGGCGTGGAGATCG
ATTTTTCGCCTGGCAAGGCCCGTCTGCGCGGTGGACAGCGTCTGCGCGCGACCGATATCGCGGTACCTGCGGATTTTTCG
TCGGCTGCATTCTTCATCGTCGCGGCCAGCGTCGTTCCCGGCTCGGAAGTGGTGCTGCGCGCGGTCGGATTGAATCCGCG
CCGCACCGGGCTGCTGGCCGCGTTGCGCCTGATGGGCGCAGATATTGGCGAAGAAAACCATGCCGAACACGGCGGTGAGC
CGGTCGCCGATCTGCACGTGCGTTACGCGCCATTGCGCGGTGCGCAGATTCCCGAGGCGCTGGTGCCGGACATGATCGAC
GAATTCCCGGCCTTGTTCGTGGCTGCCGCTGCAGCGAGCGGGCAGACCGTGGTGACCGGCGCCGCCGAATTGCGCGTCAA
GGAGTCCGATCGCCTGGCGGCGATGGCCACCGGCCTGCGCACGCTTGGCATACAGGTCGACGAAACGCCGGATGGGGCGA
CCATCCATGGCGGCAGCATCGGCAGCGGCGTGATCGAAAGTCATGGCGACCATCGCATTGCCATGGCGTTCGCCATTGCC
GGCCAGCTATCCATGGGACAGGTGCAGGTGAACGACGTGGCGAATGTGGCGACCTCGTTCCCGGGCTTCGACACCCTGGC
ACAGGACGTCGGATTCGGGCTGGAAACTGCCGGGCATCGGTAA

Upstream 100 bases:

>100_bases
TCCATGCCGGCGCGCCGCAACCTTGTATCGACGGCGACGCCGCACCCTTCTTCAAGCGCATCGTCGGCGTTGGCGATGCC
GCAGCCATCGGATCACATGC

Downstream 100 bases:

>100_bases
CGCGTCTGTTCTCCGCCGAGTGGCTTGGCAGGGTCTGCCAGCGAGTCAGGAGTCAAACGACGCCCGCGACATCTCTACCG
TTGAGGGCAAACGTTGAGGG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSSSTHHWIARRGTALQGSLAIPGDKSVSHRAVMFAALADGVSQIDGFLEGEDTRSTAAIFAKLGVRIETPSASQRIVHG
VGVDGLQPPTEVLDCGNAGTGMRLLAGLLAAQRFDSVLVGDASLSKRPMRRVTGPLAQMGARIETQDDGTPPLHVRGGQA
LHGIDFVSPVASAQVKSAVLLAGLYAQGETSVTEPHPTRDYTERMLSAFGVEIDFSPGKARLRGGQRLRATDIAVPADFS
SAAFFIVAASVVPGSEVVLRAVGLNPRRTGLLAALRLMGADIGEENHAEHGGEPVADLHVRYAPLRGAQIPEALVPDMID
EFPALFVAAAAASGQTVVTGAAELRVKESDRLAAMATGLRTLGIQVDETPDGATIHGGSIGSGVIESHGDHRIAMAFAIA
GQLSMGQVQVNDVANVATSFPGFDTLAQDVGFGLETAGHR

Sequences:

>Translated_440_residues
MSSSTHHWIARRGTALQGSLAIPGDKSVSHRAVMFAALADGVSQIDGFLEGEDTRSTAAIFAKLGVRIETPSASQRIVHG
VGVDGLQPPTEVLDCGNAGTGMRLLAGLLAAQRFDSVLVGDASLSKRPMRRVTGPLAQMGARIETQDDGTPPLHVRGGQA
LHGIDFVSPVASAQVKSAVLLAGLYAQGETSVTEPHPTRDYTERMLSAFGVEIDFSPGKARLRGGQRLRATDIAVPADFS
SAAFFIVAASVVPGSEVVLRAVGLNPRRTGLLAALRLMGADIGEENHAEHGGEPVADLHVRYAPLRGAQIPEALVPDMID
EFPALFVAAAAASGQTVVTGAAELRVKESDRLAAMATGLRTLGIQVDETPDGATIHGGSIGSGVIESHGDHRIAMAFAIA
GQLSMGQVQVNDVANVATSFPGFDTLAQDVGFGLETAGHR
>Mature_439_residues
SSSTHHWIARRGTALQGSLAIPGDKSVSHRAVMFAALADGVSQIDGFLEGEDTRSTAAIFAKLGVRIETPSASQRIVHGV
GVDGLQPPTEVLDCGNAGTGMRLLAGLLAAQRFDSVLVGDASLSKRPMRRVTGPLAQMGARIETQDDGTPPLHVRGGQAL
HGIDFVSPVASAQVKSAVLLAGLYAQGETSVTEPHPTRDYTERMLSAFGVEIDFSPGKARLRGGQRLRATDIAVPADFSS
AAFFIVAASVVPGSEVVLRAVGLNPRRTGLLAALRLMGADIGEENHAEHGGEPVADLHVRYAPLRGAQIPEALVPDMIDE
FPALFVAAAAASGQTVVTGAAELRVKESDRLAAMATGLRTLGIQVDETPDGATIHGGSIGSGVIESHGDHRIAMAFAIAG
QLSMGQVQVNDVANVATSFPGFDTLAQDVGFGLETAGHR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=447, Percent_Identity=32.2147651006711, Blast_Score=124, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6320332, Length=464, Percent_Identity=26.9396551724138, Blast_Score=128, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_XANAC (Q8PLY5)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_641982.1
- ProteinModelPortal:   Q8PLY5
- SMR:   Q8PLY5
- GeneID:   1155721
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC1650
- NMPDR:   fig|190486.1.peg.1626
- HOGENOM:   HBG646626
- OMA:   LSRNHTE
- ProtClustDB:   PRK02427
- BioCyc:   XAXO190486:XAC1650-MONOMER
- BRENDA:   2.5.1.19
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 45686; Mature: 45555

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MSSSTHHWIARRGTALQGSLAIPGDKSVSHRAVMFAALADGVSQIDGFLEGEDTRSTAAI
CCCCCCCHHHHCCCEEECCEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
FAKLGVRIETPSASQRIVHGVGVDGLQPPTEVLDCGNAGTGMRLLAGLLAAQRFDSVLVG
HHHHCCEEECCCCHHHHHEECCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEC
DASLSKRPMRRVTGPLAQMGARIETQDDGTPPLHVRGGQALHGIDFVSPVASAQVKSAVL
CCHHCCCHHHHHHCHHHHHCCEEECCCCCCCCEEECCCCEECCCHHHHHHHHHHHHHHHH
LAGLYAQGETSVTEPHPTRDYTERMLSAFGVEIDFSPGKARLRGGQRLRATDIAVPADFS
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCHHHHCCCCEEEEEEEECCCCCC
SAAFFIVAASVVPGSEVVLRAVGLNPRRTGLLAALRLMGADIGEENHAEHGGEPVADLHV
CCEEEEEEECCCCCCHHEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHEEE
RYAPLRGAQIPEALVPDMIDEFPALFVAAAAASGQTVVTGAAELRVKESDRLAAMATGLR
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHEEECCCCHHHHHHHHHH
TLGIQVDETPDGATIHGGSIGSGVIESHGDHRIAMAFAIAGQLSMGQVQVNDVANVATSF
HCCEEEECCCCCCEEECCCCCCCHHHCCCCCEEEEEEEECCCCCCCEEEHHHHHHHHHCC
PGFDTLAQDVGFGLETAGHR
CCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SSSTHHWIARRGTALQGSLAIPGDKSVSHRAVMFAALADGVSQIDGFLEGEDTRSTAAI
CCCCCCHHHHCCCEEECCEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
FAKLGVRIETPSASQRIVHGVGVDGLQPPTEVLDCGNAGTGMRLLAGLLAAQRFDSVLVG
HHHHCCEEECCCCHHHHHEECCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEC
DASLSKRPMRRVTGPLAQMGARIETQDDGTPPLHVRGGQALHGIDFVSPVASAQVKSAVL
CCHHCCCHHHHHHCHHHHHCCEEECCCCCCCCEEECCCCEECCCHHHHHHHHHHHHHHHH
LAGLYAQGETSVTEPHPTRDYTERMLSAFGVEIDFSPGKARLRGGQRLRATDIAVPADFS
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCHHHHCCCCEEEEEEEECCCCCC
SAAFFIVAASVVPGSEVVLRAVGLNPRRTGLLAALRLMGADIGEENHAEHGGEPVADLHV
CCEEEEEEECCCCCCHHEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHEEE
RYAPLRGAQIPEALVPDMIDEFPALFVAAAAASGQTVVTGAAELRVKESDRLAAMATGLR
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHEEECCCCHHHHHHHHHH
TLGIQVDETPDGATIHGGSIGSGVIESHGDHRIAMAFAIAGQLSMGQVQVNDVANVATSF
HCCEEEECCCCCCEEECCCCCCCHHHCCCCCEEEEEEEECCCCCCCEEEHHHHHHHHHCC
PGFDTLAQDVGFGLETAGHR
CCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217