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The map label for this gene is pheA [H]

Identifier: 21242399

GI number: 21242399

Start: 1900494

End: 1901702

Strand: Direct

Name: pheA [H]

Synonym: XAC1649

Alternate gene names: 21242399

Gene position: 1900494-1901702 (Clockwise)

Preceding gene: 21242398

Following gene: 21242400

Centisome position: 36.72

GC content: 62.2

Gene sequence:

>1209_bases
ATGGCCCCCAAGTCCAACAAGCCCACGGCCGCCACAGGCGGCAACAAAAAGCCGACCAAGACAGCGACGAGTGCTTCAGC
CGGCAAGCCTGCAAACACGCCGGCTGAAAAGGCCGCGATCAAGACCGCCGCGCCGGTGCTGGCCGATGTGCGTGCCAAGA
TCGACGAGATCGACCGCAATATCCAGGCGCTGATTGCCGAGCGCGCCAACTTCGCGCATCAGGTCGGCAAGGCCAAGGGC
AAGCTTGCGGCGGCGGTGGATTACTACCGCCCCGAGCGCGAGGCGCAGGTGCTGCGCATGGTGGTGGACCGCAACGAAGG
CCCGCTCAGCGACGAAGTGCTGGTGCACGTCTACCGCGAAATCATGTCGGCGTGCCTGGCCCAGCAGGAGCCGCTGAAGA
TCGGTTATCTCGGCCCGGAAGGCACCTTCAGCCAGCAGGCGGTGCTCAAGCATTTCGGCCGCTCGGCGGTGGGCTTGCCG
ATGGCGACCATCGAAGAAGTGTTCCAGGAAGTGGAGGCAGGCAATGCCGACTTCGGCGTGGTGCCGGTGGAAAATTCGGG
GCAGGGCACCATCCAGGTCACCCTGGACATGTTCCTGACCTCCAACCTGAAAATCTGCGGCGAAGTCGAGCTGCGAGTGC
ATCAATATCTGCTCTCGCGCAACGGCCGGCTGGAAGATATCGAACGCATCTACGCGCATTCGCAGTCGTTCGCGCAGACC
GCGGGTTGGTTGCGCTCGCATTTGCCCAAGGTGGAAAAGATCGCAGTGTCCAGCAACGCCGAAGGCGCACGCCGCGCACG
CAATGCTGAAGATGCCGCGGCCATCGGCGGCGAAAGCGCAGCGCATGTGTATGGCTTGAAGAAAGTCATCATGAAGTCGA
TCGAGGACGACGACGACAACACCACGCGCTTCTTGGTGATCGGGCGGCAGATCTTTCCTTCGTCCGGGCACGACCGCACG
TCGGTGCTGGTGTTCATCCACGACAAGCCGGGTGCGTTGTTCGACGTGCTCAGCCCATTCGCACGCCACGGCATCAGCAT
GAACCGCATCGAATCGCGGCCCTCGCATCAGGCCAAGTGGGAATACGGCTTCTTCATCGATCTGATCGGCCATGTCGAAG
ACGATGCGATGAAGCAGGCGCTGGCCGAACTGAAAGCGCACTCGGCACAGATCAAGGTGCTGGGTTCGTATCCGGTGGCC
ATTCCCTGA

Upstream 100 bases:

>100_bases
CAGCAGCGTCACGGCTGAGTCTTCATCTACCTGCGGCGTCTGCCGCGCAGGCGCATGCGCTGCCAGCGCACATGCGCCGC
CATTTTAGGAATGCCCAGCA

Downstream 100 bases:

>100_bases
GCATTGAGGCTCGATACGACAATCCATGCCGGCGCGCCGCAACCTTGTATCGACGGCGACGCCGCACCCTTCTTCAAGCG
CATCGTCGGCGTTGGCGATG

Product: P-protein

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MAPKSNKPTAATGGNKKPTKTATSASAGKPANTPAEKAAIKTAAPVLADVRAKIDEIDRNIQALIAERANFAHQVGKAKG
KLAAAVDYYRPEREAQVLRMVVDRNEGPLSDEVLVHVYREIMSACLAQQEPLKIGYLGPEGTFSQQAVLKHFGRSAVGLP
MATIEEVFQEVEAGNADFGVVPVENSGQGTIQVTLDMFLTSNLKICGEVELRVHQYLLSRNGRLEDIERIYAHSQSFAQT
AGWLRSHLPKVEKIAVSSNAEGARRARNAEDAAAIGGESAAHVYGLKKVIMKSIEDDDDNTTRFLVIGRQIFPSSGHDRT
SVLVFIHDKPGALFDVLSPFARHGISMNRIESRPSHQAKWEYGFFIDLIGHVEDDAMKQALAELKAHSAQIKVLGSYPVA
IP

Sequences:

>Translated_402_residues
MAPKSNKPTAATGGNKKPTKTATSASAGKPANTPAEKAAIKTAAPVLADVRAKIDEIDRNIQALIAERANFAHQVGKAKG
KLAAAVDYYRPEREAQVLRMVVDRNEGPLSDEVLVHVYREIMSACLAQQEPLKIGYLGPEGTFSQQAVLKHFGRSAVGLP
MATIEEVFQEVEAGNADFGVVPVENSGQGTIQVTLDMFLTSNLKICGEVELRVHQYLLSRNGRLEDIERIYAHSQSFAQT
AGWLRSHLPKVEKIAVSSNAEGARRARNAEDAAAIGGESAAHVYGLKKVIMKSIEDDDDNTTRFLVIGRQIFPSSGHDRT
SVLVFIHDKPGALFDVLSPFARHGISMNRIESRPSHQAKWEYGFFIDLIGHVEDDAMKQALAELKAHSAQIKVLGSYPVA
IP
>Mature_401_residues
APKSNKPTAATGGNKKPTKTATSASAGKPANTPAEKAAIKTAAPVLADVRAKIDEIDRNIQALIAERANFAHQVGKAKGK
LAAAVDYYRPEREAQVLRMVVDRNEGPLSDEVLVHVYREIMSACLAQQEPLKIGYLGPEGTFSQQAVLKHFGRSAVGLPM
ATIEEVFQEVEAGNADFGVVPVENSGQGTIQVTLDMFLTSNLKICGEVELRVHQYLLSRNGRLEDIERIYAHSQSFAQTA
GWLRSHLPKVEKIAVSSNAEGARRARNAEDAAAIGGESAAHVYGLKKVIMKSIEDDDDNTTRFLVIGRQIFPSSGHDRTS
VLVFIHDKPGALFDVLSPFARHGISMNRIESRPSHQAKWEYGFFIDLIGHVEDDAMKQALAELKAHSAQIKVLGSYPVAI
P

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=382, Percent_Identity=31.151832460733, Blast_Score=163, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6324013, Length=338, Percent_Identity=28.1065088757396, Blast_Score=112, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 43709; Mature: 43578

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPKSNKPTAATGGNKKPTKTATSASAGKPANTPAEKAAIKTAAPVLADVRAKIDEIDRN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IQALIAERANFAHQVGKAKGKLAAAVDYYRPEREAQVLRMVVDRNEGPLSDEVLVHVYRE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
IMSACLAQQEPLKIGYLGPEGTFSQQAVLKHFGRSAVGLPMATIEEVFQEVEAGNADFGV
HHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
VPVENSGQGTIQVTLDMFLTSNLKICGEVELRVHQYLLSRNGRLEDIERIYAHSQSFAQT
EECCCCCCEEEEEEEEEHHCCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AGWLRSHLPKVEKIAVSSNAEGARRARNAEDAAAIGGESAAHVYGLKKVIMKSIEDDDDN
HHHHHHHCCHHHEEEECCCCCHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
TTRFLVIGRQIFPSSGHDRTSVLVFIHDKPGALFDVLSPFARHGISMNRIESRPSHQAKW
CEEEEEEEHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCC
EYGFFIDLIGHVEDDAMKQALAELKAHSAQIKVLGSYPVAIP
CCCHHEEHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCC
>Mature Secondary Structure 
APKSNKPTAATGGNKKPTKTATSASAGKPANTPAEKAAIKTAAPVLADVRAKIDEIDRN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IQALIAERANFAHQVGKAKGKLAAAVDYYRPEREAQVLRMVVDRNEGPLSDEVLVHVYRE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
IMSACLAQQEPLKIGYLGPEGTFSQQAVLKHFGRSAVGLPMATIEEVFQEVEAGNADFGV
HHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
VPVENSGQGTIQVTLDMFLTSNLKICGEVELRVHQYLLSRNGRLEDIERIYAHSQSFAQT
EECCCCCCEEEEEEEEEHHCCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AGWLRSHLPKVEKIAVSSNAEGARRARNAEDAAAIGGESAAHVYGLKKVIMKSIEDDDDN
HHHHHHHCCHHHEEEECCCCCHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
TTRFLVIGRQIFPSSGHDRTSVLVFIHDKPGALFDVLSPFARHGISMNRIESRPSHQAKW
CEEEEEEEHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCC
EYGFFIDLIGHVEDDAMKQALAELKAHSAQIKVLGSYPVAIP
CCCHHEEHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1919506; 10368439 [H]