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The map label for this gene is era [H]

Identifier: 21242079

GI number: 21242079

Start: 1531219

End: 1532118

Strand: Direct

Name: era [H]

Synonym: XAC1326

Alternate gene names: 21242079

Gene position: 1531219-1532118 (Clockwise)

Preceding gene: 21242078

Following gene: 21242080

Centisome position: 29.59

GC content: 66.44

Gene sequence:

>900_bases
GTGAGCGAAATCACTTCCCCTCACCGCAGCGGTAGCGTTGCGGTGATCGGCCGGCCCAACGTCGGCAAGTCCACCCTGAC
CAACGCCCTGGTCGGCGCGAAGGTCAGCATCGTCTCCAACCGGCCGCAGACCACGCGCCATCGGTTGCTGGGCATCGCCA
CCTTCCCGGAAGGACAGCTGGTGCTGGTCGATACTCCGGGATTGCACCGCGAGCAGAAGCGCGCAATGAACCGGGTGATG
AATCGCGCTGCGCGCGGCTCGCTCGAGGGGGTGGACGCGGCGGTCCTGGTGATCGAAGCCGGCCGCTGGGACGAGGAAGA
CACGCTGGCGTTTCGCGTGCTCAGCGACGCCGGCGTGCCGGTGGTGCTGGTGGTGAACAAGGTCGACCGGCTCAAGGACA
AGACCGCGCTGTTCCCGTTCCTGGCCCAGGTCAGCGAGGGGCGCACCTTCGCCGCCGTGCATCCGGTGTCTGCGCTCAAG
CGCAAGGGCCTGGACGCGTTGGTCGGCGACCTGCTCAAGCTGGTGCCCGAAGCCGAGGCGATGTTCGGCGAAGACGAGAT
CACCGACCGCAGTCAGCGCTTTTTGGCCGGCGAACTGGTGCGGGAGCAGCTGATGCGTCAGCTCGGCGAAGAGCTGCCGT
ATGCCACCACCGTTGAGATCGAGCGTTTCGCCGAAGATGGCGCGCTGCTGCGCATCGGTGCGGTGATCTGGGTCGAGCGC
GAAGGCCAGAAGGCGATCGTGATAGGCAAGGGCGGCACCCGGTTGAAAGAAATTGGCGGCAAGGCGCGCCTGCAGATGGA
GCGCCTGTTCGGTGCCAAGGTGTTCCTGGAAACCTGGGTGCGCGTGCGCGAAGGCTGGTCGGACGACGAGGCGGCGCTGA
AGGCGTTCGGGTACGAATGA

Upstream 100 bases:

>100_bases
TGGAGCAGCCCGTTGCCCGCGCCGAGGGCCAGGGCACCTCGCGTCGCCTCGCAGAGCAACAGGCGGCGACTCTTGTCATC
GCACAACTGGATTCAAACAC

Downstream 100 bases:

>100_bases
GGCCGGGAAGGCCGGGACCCGGGACCCGGGTCCCGGGTCCCGGAAAAAAAAGCTGGGTCAGGCTTTTGGTCGGCATGCTG
CCGAGGAGAGGTTTTTTCGT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSEITSPHRSGSVAVIGRPNVGKSTLTNALVGAKVSIVSNRPQTTRHRLLGIATFPEGQLVLVDTPGLHREQKRAMNRVM
NRAARGSLEGVDAAVLVIEAGRWDEEDTLAFRVLSDAGVPVVLVVNKVDRLKDKTALFPFLAQVSEGRTFAAVHPVSALK
RKGLDALVGDLLKLVPEAEAMFGEDEITDRSQRFLAGELVREQLMRQLGEELPYATTVEIERFAEDGALLRIGAVIWVER
EGQKAIVIGKGGTRLKEIGGKARLQMERLFGAKVFLETWVRVREGWSDDEAALKAFGYE

Sequences:

>Translated_299_residues
MSEITSPHRSGSVAVIGRPNVGKSTLTNALVGAKVSIVSNRPQTTRHRLLGIATFPEGQLVLVDTPGLHREQKRAMNRVM
NRAARGSLEGVDAAVLVIEAGRWDEEDTLAFRVLSDAGVPVVLVVNKVDRLKDKTALFPFLAQVSEGRTFAAVHPVSALK
RKGLDALVGDLLKLVPEAEAMFGEDEITDRSQRFLAGELVREQLMRQLGEELPYATTVEIERFAEDGALLRIGAVIWVER
EGQKAIVIGKGGTRLKEIGGKARLQMERLFGAKVFLETWVRVREGWSDDEAALKAFGYE
>Mature_298_residues
SEITSPHRSGSVAVIGRPNVGKSTLTNALVGAKVSIVSNRPQTTRHRLLGIATFPEGQLVLVDTPGLHREQKRAMNRVMN
RAARGSLEGVDAAVLVIEAGRWDEEDTLAFRVLSDAGVPVVLVVNKVDRLKDKTALFPFLAQVSEGRTFAAVHPVSALKR
KGLDALVGDLLKLVPEAEAMFGEDEITDRSQRFLAGELVREQLMRQLGEELPYATTVEIERFAEDGALLRIGAVIWVERE
GQKAIVIGKGGTRLKEIGGKARLQMERLFGAKVFLETWVRVREGWSDDEAALKAFGYE

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=312, Percent_Identity=26.2820512820513, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI1788919, Length=290, Percent_Identity=48.9655172413793, Blast_Score=285, Evalue=2e-78,
Organism=Escherichia coli, GI87082120, Length=177, Percent_Identity=33.8983050847458, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646434, Length=303, Percent_Identity=27.0627062706271, Blast_Score=101, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 32804; Mature: 32673

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEITSPHRSGSVAVIGRPNVGKSTLTNALVGAKVSIVSNRPQTTRHRLLGIATFPEGQL
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCEEEEECCCCCHHHHHEEEEEECCCCCE
VLVDTPGLHREQKRAMNRVMNRAARGSLEGVDAAVLVIEAGRWDEEDTLAFRVLSDAGVP
EEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHEEEEEECCCCCE
VVLVVNKVDRLKDKTALFPFLAQVSEGRTFAAVHPVSALKRKGLDALVGDLLKLVPEAEA
EEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHCCHHHHHHHHHHHCCHHHH
MFGEDEITDRSQRFLAGELVREQLMRQLGEELPYATTVEIERFAEDGALLRIGAVIWVER
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHCCCCEEEEEEEEEEEE
EGQKAIVIGKGGTRLKEIGGKARLQMERLFGAKVFLETWVRVREGWSDDEAALKAFGYE
CCCEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCC
>Mature Secondary Structure 
SEITSPHRSGSVAVIGRPNVGKSTLTNALVGAKVSIVSNRPQTTRHRLLGIATFPEGQL
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCEEEEECCCCCHHHHHEEEEEECCCCCE
VLVDTPGLHREQKRAMNRVMNRAARGSLEGVDAAVLVIEAGRWDEEDTLAFRVLSDAGVP
EEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHEEEEEECCCCCE
VVLVVNKVDRLKDKTALFPFLAQVSEGRTFAAVHPVSALKRKGLDALVGDLLKLVPEAEA
EEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHCCHHHHHHHHHHHCCHHHH
MFGEDEITDRSQRFLAGELVREQLMRQLGEELPYATTVEIERFAEDGALLRIGAVIWVER
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHCCCCEEEEEEEEEEEE
EGQKAIVIGKGGTRLKEIGGKARLQMERLFGAKVFLETWVRVREGWSDDEAALKAFGYE
CCCEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA