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The map label for this gene is hsp90xc [H]

Identifier: 21242020

GI number: 21242020

Start: 1448098

End: 1449966

Strand: Direct

Name: hsp90xc [H]

Synonym: XAC1267

Alternate gene names: 21242020

Gene position: 1448098-1449966 (Clockwise)

Preceding gene: 21242019

Following gene: 21242021

Centisome position: 27.98

GC content: 66.4

Gene sequence:

>1869_bases
ATGCAAGATCCCACTCCCGGGGCGACCGACGCCTCGCAGATCCGCCGGGCAGGCGTCGATCTCAATGGACTGATGTCGGT
CCTCAGCAAGCACCTGTATTCCACCCCGGTGGTGGCGCTGCGCGAGTTGGTGCAGAACGCGCACGATTCCATCCTGCGTC
GTCGTCTGGAACAACCCGATTGGGACGGCGAATCGCGCATCGAGGTGCATGCCGATACCGCGCAGGGCATCGTGCGCATC
GTCGATACCGGTGCCGGACTGACCCAGCAGGAGATCCACGACTACCTGGCTACCGTGGGCGTGGGATATACGCGCGGGCT
GCGCCAGGGCGGCCACGAGGACAGCGGCCTGATCGGCATGTTCGGGCTGGGTTTCTTGTCCGCCTTCGTGCTGGCGCGGC
GGGTGACCGTGCGCACCACCTCCTACCAGTCCCCCACGCTGGGCCATTGCTACATCTCCAGCAACGCCGAGCAGTACACG
GTCAGCCCGATTCCTGCGCGTGCGCAGGTGGGCACCGAGGTGGTGCTGGAGTTGCACAGCGACTATCTGTCGTTGGCTCA
GGAAGGACGGCTGCGCGAGATTCTGTCGCGCTATTGCGCGCTGTTGCGCGAGCCGATCTGGATCGGCGCTGCGACGCAGC
CGATCAATCCCGAGCCGCCGCCGTGGCGCGTGCAGGACGCCGCACCGCTGCATCCGGTGCAGGCCTGGCGCCGTCAACGC
GAGTTCGCCGCGCGCTTCGAGCGCAATTTCGAGCCGTTGTGCTGCATGCCGGTACGTGCGGAAGAGGGCAGCGATGCAGT
CGGCCTGCTGTGGGTGCAGGACGGTGCGACCTACGGCACCAGCGACAACCGCAATCTCTCGGTCTTCCTGCGCGGCATGT
TGCTGGATGACAACGCGCGCGAACTGCTGCCGCCGTGGGCGGGCTTCATCGGTGGGGTGATCGAATCCAATCGGTTGACG
CCTACCGCAAGCCGCGAGGATCTGCAGCGCGATACGGTCTATAGCGCGGTGCAGCACGCCTTGTCCGAAGCCTTGGTGCA
GGGCCTGGCCGATGTGGCGCGTCAGCAACCGGAGGCATGGCGACGCATCCTGCTGCGGCATAACGAAGCCCTGCTGGGCG
CAGCGTTGTGCGATGAGCGCCTGTTCGGATTACTGCTGGAACACGTGCGGGTACCGACATCGCAAGGCGATCTGCCGGCA
CAGCAATTGCCATCGCGCGGCGCGGTGCACGTGATCCTCGATAGCGACAGCGGTTTCGAAGAAATGCTGTTCCGCGCGAT
GGGCGTGCCGGTCGCCTATGGCAACCGGTATGCGGTGGTGCCGTTTCTGCGGCGCTGGGCGCAGGCCAAGGGTGTGCGTC
TGGTCGAGCTGGGCACCGAGCAGGGCAACCGCCAGCTGTTCCACCTCGATACGCTGCCGGCCGACGAACTGGCCTGGCTG
GAACAGCATTTGGGCGATGGCGAAGCGCTGGTGCCTGCGCGTTTCAGTCCGCAGGAACTGCCGTTGGTGGTAGTGCCCGA
CCGCGAGGCCGAGCTCAAACGCCGCCTGGAGCAGGACGAGAGCGACAAGCGCGTGTCCACCGCCGCGTTGCGCCTGGCGC
GGCAGTTCACCGCGCGCATCGAAGCGCGGCAGACCCAGCGGCTGTATCTGAATCTGGATAATCCCGCGCTGCAGGCCTTG
CTGGACGCGCAGCGCGCAGGCAACCCACAGGCAGCGGTGGCGGCACGCTTGCTGCGCGCGCTCAAGGTGATCGTCTCGGC
GCAAGGGCGCACGCAGCCGCAGGCGGGCAGCACCGAATCGGGCGTTTCCGATCTCAACAAGGCCTTCGGCGATTTCGCTG
GGACCGTGACCCAATTGCTGGCGCGCTGA

Upstream 100 bases:

>100_bases
CGTGCAATGTGGGGTTCCGGCTATCCTTTCCGGCTGGCACTGGCACCCAGGGGGACGCGTCCGAGGATGGGCGTCGTCGC
CGAGGAAACGACGACCGATC

Downstream 100 bases:

>100_bases
GCGCCGCATCGCAGGAGCGACACGATGGAAATCTGGAACTGGGTAGAAAAGCTGCAGGACGATCTGGGCGAAGCCGGCCA
GCCGCAAAATGCGCAGCTGC

Product: Hsp90xo protein

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MQDPTPGATDASQIRRAGVDLNGLMSVLSKHLYSTPVVALRELVQNAHDSILRRRLEQPDWDGESRIEVHADTAQGIVRI
VDTGAGLTQQEIHDYLATVGVGYTRGLRQGGHEDSGLIGMFGLGFLSAFVLARRVTVRTTSYQSPTLGHCYISSNAEQYT
VSPIPARAQVGTEVVLELHSDYLSLAQEGRLREILSRYCALLREPIWIGAATQPINPEPPPWRVQDAAPLHPVQAWRRQR
EFAARFERNFEPLCCMPVRAEEGSDAVGLLWVQDGATYGTSDNRNLSVFLRGMLLDDNARELLPPWAGFIGGVIESNRLT
PTASREDLQRDTVYSAVQHALSEALVQGLADVARQQPEAWRRILLRHNEALLGAALCDERLFGLLLEHVRVPTSQGDLPA
QQLPSRGAVHVILDSDSGFEEMLFRAMGVPVAYGNRYAVVPFLRRWAQAKGVRLVELGTEQGNRQLFHLDTLPADELAWL
EQHLGDGEALVPARFSPQELPLVVVPDREAELKRRLEQDESDKRVSTAALRLARQFTARIEARQTQRLYLNLDNPALQAL
LDAQRAGNPQAAVAARLLRALKVIVSAQGRTQPQAGSTESGVSDLNKAFGDFAGTVTQLLAR

Sequences:

>Translated_622_residues
MQDPTPGATDASQIRRAGVDLNGLMSVLSKHLYSTPVVALRELVQNAHDSILRRRLEQPDWDGESRIEVHADTAQGIVRI
VDTGAGLTQQEIHDYLATVGVGYTRGLRQGGHEDSGLIGMFGLGFLSAFVLARRVTVRTTSYQSPTLGHCYISSNAEQYT
VSPIPARAQVGTEVVLELHSDYLSLAQEGRLREILSRYCALLREPIWIGAATQPINPEPPPWRVQDAAPLHPVQAWRRQR
EFAARFERNFEPLCCMPVRAEEGSDAVGLLWVQDGATYGTSDNRNLSVFLRGMLLDDNARELLPPWAGFIGGVIESNRLT
PTASREDLQRDTVYSAVQHALSEALVQGLADVARQQPEAWRRILLRHNEALLGAALCDERLFGLLLEHVRVPTSQGDLPA
QQLPSRGAVHVILDSDSGFEEMLFRAMGVPVAYGNRYAVVPFLRRWAQAKGVRLVELGTEQGNRQLFHLDTLPADELAWL
EQHLGDGEALVPARFSPQELPLVVVPDREAELKRRLEQDESDKRVSTAALRLARQFTARIEARQTQRLYLNLDNPALQAL
LDAQRAGNPQAAVAARLLRALKVIVSAQGRTQPQAGSTESGVSDLNKAFGDFAGTVTQLLAR
>Mature_622_residues
MQDPTPGATDASQIRRAGVDLNGLMSVLSKHLYSTPVVALRELVQNAHDSILRRRLEQPDWDGESRIEVHADTAQGIVRI
VDTGAGLTQQEIHDYLATVGVGYTRGLRQGGHEDSGLIGMFGLGFLSAFVLARRVTVRTTSYQSPTLGHCYISSNAEQYT
VSPIPARAQVGTEVVLELHSDYLSLAQEGRLREILSRYCALLREPIWIGAATQPINPEPPPWRVQDAAPLHPVQAWRRQR
EFAARFERNFEPLCCMPVRAEEGSDAVGLLWVQDGATYGTSDNRNLSVFLRGMLLDDNARELLPPWAGFIGGVIESNRLT
PTASREDLQRDTVYSAVQHALSEALVQGLADVARQQPEAWRRILLRHNEALLGAALCDERLFGLLLEHVRVPTSQGDLPA
QQLPSRGAVHVILDSDSGFEEMLFRAMGVPVAYGNRYAVVPFLRRWAQAKGVRLVELGTEQGNRQLFHLDTLPADELAWL
EQHLGDGEALVPARFSPQELPLVVVPDREAELKRRLEQDESDKRVSTAALRLARQFTARIEARQTQRLYLNLDNPALQAL
LDAQRAGNPQAAVAARLLRALKVIVSAQGRTQPQAGSTESGVSDLNKAFGDFAGTVTQLLAR

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=359, Percent_Identity=24.5125348189415, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI4507677, Length=424, Percent_Identity=22.6415094339623, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI153792590, Length=192, Percent_Identity=29.1666666666667, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI20149594, Length=196, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI154146191, Length=192, Percent_Identity=29.1666666666667, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1786679, Length=367, Percent_Identity=28.6103542234332, Blast_Score=141, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17559162, Length=434, Percent_Identity=22.8110599078341, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI115535167, Length=363, Percent_Identity=22.3140495867769, Blast_Score=105, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI115535205, Length=363, Percent_Identity=22.3140495867769, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17542208, Length=369, Percent_Identity=23.3062330623306, Blast_Score=97, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6325016, Length=410, Percent_Identity=22.6829268292683, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323840, Length=397, Percent_Identity=22.6700251889169, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24586016, Length=360, Percent_Identity=25.2777777777778, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21357739, Length=384, Percent_Identity=23.9583333333333, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI17647529, Length=192, Percent_Identity=29.1666666666667, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 68656; Mature: 68656

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDPTPGATDASQIRRAGVDLNGLMSVLSKHLYSTPVVALRELVQNAHDSILRRRLEQPD
CCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC
WDGESRIEVHADTAQGIVRIVDTGAGLTQQEIHDYLATVGVGYTRGLRQGGHEDSGLIGM
CCCCCEEEEECCHHHHHEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHH
FGLGFLSAFVLARRVTVRTTSYQSPTLGHCYISSNAEQYTVSPIPARAQVGTEVVLELHS
HHHHHHHHHHHHHHHHEEECCCCCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHH
DYLSLAQEGRLREILSRYCALLREPIWIGAATQPINPEPPPWRVQDAAPLHPVQAWRRQR
HHHHHHHCCHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
EFAARFERNFEPLCCMPVRAEEGSDAVGLLWVQDGATYGTSDNRNLSVFLRGMLLDDNAR
HHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEECCCEECCCCCCCEEEEEEEEEECCCCH
ELLPPWAGFIGGVIESNRLTPTASREDLQRDTVYSAVQHALSEALVQGLADVARQQPEAW
HHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RRILLRHNEALLGAALCDERLFGLLLEHVRVPTSQGDLPAQQLPSRGAVHVILDSDSGFE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCEEEEECCCCCHH
EMLFRAMGVPVAYGNRYAVVPFLRRWAQAKGVRLVELGTEQGNRQLFHLDTLPADELAWL
HHHHHHHCCCEEECCCEEHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCHHHHHHH
EQHLGDGEALVPARFSPQELPLVVVPDREAELKRRLEQDESDKRVSTAALRLARQFTARI
HHHCCCCCEECCCCCCCCCCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EARQTQRLYLNLDNPALQALLDAQRAGNPQAAVAARLLRALKVIVSAQGRTQPQAGSTES
HHHCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
GVSDLNKAFGDFAGTVTQLLAR
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQDPTPGATDASQIRRAGVDLNGLMSVLSKHLYSTPVVALRELVQNAHDSILRRRLEQPD
CCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC
WDGESRIEVHADTAQGIVRIVDTGAGLTQQEIHDYLATVGVGYTRGLRQGGHEDSGLIGM
CCCCCEEEEECCHHHHHEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHH
FGLGFLSAFVLARRVTVRTTSYQSPTLGHCYISSNAEQYTVSPIPARAQVGTEVVLELHS
HHHHHHHHHHHHHHHHEEECCCCCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHH
DYLSLAQEGRLREILSRYCALLREPIWIGAATQPINPEPPPWRVQDAAPLHPVQAWRRQR
HHHHHHHCCHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
EFAARFERNFEPLCCMPVRAEEGSDAVGLLWVQDGATYGTSDNRNLSVFLRGMLLDDNAR
HHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEECCCEECCCCCCCEEEEEEEEEECCCCH
ELLPPWAGFIGGVIESNRLTPTASREDLQRDTVYSAVQHALSEALVQGLADVARQQPEAW
HHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RRILLRHNEALLGAALCDERLFGLLLEHVRVPTSQGDLPAQQLPSRGAVHVILDSDSGFE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCEEEEECCCCCHH
EMLFRAMGVPVAYGNRYAVVPFLRRWAQAKGVRLVELGTEQGNRQLFHLDTLPADELAWL
HHHHHHHCCCEEECCCEEHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCHHHHHHH
EQHLGDGEALVPARFSPQELPLVVVPDREAELKRRLEQDESDKRVSTAALRLARQFTARI
HHHCCCCCEECCCCCCCCCCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EARQTQRLYLNLDNPALQALLDAQRAGNPQAAVAARLLRALKVIVSAQGRTQPQAGSTES
HHHCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
GVSDLNKAFGDFAGTVTQLLAR
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]