Click here to switch to the map view.

The map label for this gene is cysW [H]

Identifier: 21241784

GI number: 21241784

Start: 1174782

End: 1175735

Strand: Direct

Name: cysW [H]

Synonym: XAC1019

Alternate gene names: 21241784

Gene position: 1174782-1175735 (Clockwise)

Preceding gene: 21241783

Following gene: 21241785

Centisome position: 22.7

GC content: 62.68

Gene sequence:

>954_bases
ATGAACGATGCTGTTTCATCGCTGCCTTCCATGTTGCCGACCCATGCCATGACCAAGCAGGCGCGTCGCATCAGCGATTC
GGCCACCAATGAGCCGCGTTGGGTGCAATGGCTGATGATCCTGGGCGCCGTGCTCTTTCTACTGGCGTTCTTGCTGCTGC
CGCTGGTGCTGGTGTTCGCCGAGGCGTTGCGTGGCGGTTGGGAAACCTTCCTGCACGCGGTAGTCGACCCGGACGCGTTG
TCGGCGATCAAGCTGACCTTGCTGGTGACTGCGATCGTGCTGCCGTTGAATCTGGTCTTCGGCGTGGCCGCGGCGTGGGC
CATCAGCAAGCATCAGTTCCGGGGCAAACGCCTGCTGGTCAGCCTGATCGACCTGCCATTCTCGGTGTCGCCGGTGGTGG
CGGGCTTGATCTTCGTGCTGATCTTCGGCCGCAACGGCTGGGCCTGGCCACTGATCGACGAAGGCTGGCATGTGCAGCTG
CCGGCGCTGGGCGACCTTGTGATCCAGTTGCCGCGGATCGTGTTCGCGTTGCCGGGCATCGTATTGGCGACCACGTTCGT
AACCTTTCCCTTCATTGCGCGCGAATTGATGCCGTTGATGGAGCAGCAGGGCAGCGACGAAGAACTGGCGGCACTGAGCC
TGGGCGCGAACGGCTGGCAGATGTTCTGGCGGGTGACGCTGCCCAATATCCGTTGGGGCCTGTTGTACGGCGTGCTGTTG
TGCGCGGCGCGTGCGATGGGCGAATTCGGGGCGGTGTCGGTGGTGTCCGGGCATATCCGTGGACGCACCAATACGCTGCC
GCTGCATGTGGAAATTCTCTACAACGAATACGCCTACAGCGCCGCATTTGCCTGCGCGTCGCTGCTGGCATTGACCGCGC
TGCTGACGTTGGCGCTGAAGACGTATCTGGAATGGCGACACGGCGATTCGCTGGCCGCCAACCACCGCCATTGA

Upstream 100 bases:

>100_bases
CGACTGCCATTGCCGCGGCCATGCTGTTGCTGTCGTTCGTGATCTTGTTGGTGGTCAATACGCTGCAGGCACGGCTGCTG
CGCTATCAACGCAGGCCCGT

Downstream 100 bases:

>100_bases
GGTGACCATGGGCATCCGCATTCACCGCCTGCGCAAGCAGTTCGAGACTTTTACCGCGCTGGACAACATCGACCTGGAAG
TGCGCCAGGGCGAGTTGCTG

Product: ABC transporter sulfate permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNDAVSSLPSMLPTHAMTKQARRISDSATNEPRWVQWLMILGAVLFLLAFLLLPLVLVFAEALRGGWETFLHAVVDPDAL
SAIKLTLLVTAIVLPLNLVFGVAAAWAISKHQFRGKRLLVSLIDLPFSVSPVVAGLIFVLIFGRNGWAWPLIDEGWHVQL
PALGDLVIQLPRIVFALPGIVLATTFVTFPFIARELMPLMEQQGSDEELAALSLGANGWQMFWRVTLPNIRWGLLYGVLL
CAARAMGEFGAVSVVSGHIRGRTNTLPLHVEILYNEYAYSAAFACASLLALTALLTLALKTYLEWRHGDSLAANHRH

Sequences:

>Translated_317_residues
MNDAVSSLPSMLPTHAMTKQARRISDSATNEPRWVQWLMILGAVLFLLAFLLLPLVLVFAEALRGGWETFLHAVVDPDAL
SAIKLTLLVTAIVLPLNLVFGVAAAWAISKHQFRGKRLLVSLIDLPFSVSPVVAGLIFVLIFGRNGWAWPLIDEGWHVQL
PALGDLVIQLPRIVFALPGIVLATTFVTFPFIARELMPLMEQQGSDEELAALSLGANGWQMFWRVTLPNIRWGLLYGVLL
CAARAMGEFGAVSVVSGHIRGRTNTLPLHVEILYNEYAYSAAFACASLLALTALLTLALKTYLEWRHGDSLAANHRH
>Mature_317_residues
MNDAVSSLPSMLPTHAMTKQARRISDSATNEPRWVQWLMILGAVLFLLAFLLLPLVLVFAEALRGGWETFLHAVVDPDAL
SAIKLTLLVTAIVLPLNLVFGVAAAWAISKHQFRGKRLLVSLIDLPFSVSPVVAGLIFVLIFGRNGWAWPLIDEGWHVQL
PALGDLVIQLPRIVFALPGIVLATTFVTFPFIARELMPLMEQQGSDEELAALSLGANGWQMFWRVTLPNIRWGLLYGVLL
CAARAMGEFGAVSVVSGHIRGRTNTLPLHVEILYNEYAYSAAFACASLLALTALLTLALKTYLEWRHGDSLAANHRH

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=305, Percent_Identity=47.5409836065574, Blast_Score=255, Evalue=2e-69,
Organism=Escherichia coli, GI1788764, Length=242, Percent_Identity=33.4710743801653, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786980, Length=196, Percent_Identity=32.6530612244898, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34850; Mature: 34850

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDAVSSLPSMLPTHAMTKQARRISDSATNEPRWVQWLMILGAVLFLLAFLLLPLVLVFA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALRGGWETFLHAVVDPDALSAIKLTLLVTAIVLPLNLVFGVAAAWAISKHQFRGKRLLV
HHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLIDLPFSVSPVVAGLIFVLIFGRNGWAWPLIDEGWHVQLPALGDLVIQLPRIVFALPGI
HHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCEEECCHHHHHHHHHHHHHHHHHHH
VLATTFVTFPFIARELMPLMEQQGSDEELAALSLGANGWQMFWRVTLPNIRWGLLYGVLL
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHH
CAARAMGEFGAVSVVSGHIRGRTNTLPLHVEILYNEYAYSAAFACASLLALTALLTLALK
HHHHHHCCCCCHHHHHHCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
TYLEWRHGDSLAANHRH
HHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNDAVSSLPSMLPTHAMTKQARRISDSATNEPRWVQWLMILGAVLFLLAFLLLPLVLVFA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALRGGWETFLHAVVDPDALSAIKLTLLVTAIVLPLNLVFGVAAAWAISKHQFRGKRLLV
HHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLIDLPFSVSPVVAGLIFVLIFGRNGWAWPLIDEGWHVQLPALGDLVIQLPRIVFALPGI
HHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCEEECCHHHHHHHHHHHHHHHHHHH
VLATTFVTFPFIARELMPLMEQQGSDEELAALSLGANGWQMFWRVTLPNIRWGLLYGVLL
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHH
CAARAMGEFGAVSVVSGHIRGRTNTLPLHVEILYNEYAYSAAFACASLLALTALLTLALK
HHHHHHCCCCCHHHHHHCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
TYLEWRHGDSLAANHRH
HHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1708375 [H]