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The map label for this gene is cysU [H]

Identifier: 21241783

GI number: 21241783

Start: 1173925

End: 1174785

Strand: Direct

Name: cysU [H]

Synonym: XAC1018

Alternate gene names: 21241783

Gene position: 1173925-1174785 (Clockwise)

Preceding gene: 21241782

Following gene: 21241784

Centisome position: 22.68

GC content: 65.39

Gene sequence:

>861_bases
ATGTCGATGTCGGTTGCACCTCACCCAGCGCCGTCATCGCGCCGACGCGTGATGCCGGGGCTGGGCCTGAGTCTGGGAAT
CACCTTGACCTGGCTTGGCCTGATCGTGCTGATCCCGCTGCTGGGTATCTTCATCAAGACCAGTGGCCTGGGCTGGGAGG
GCCTGTGGCGGGTATGGAGCGAGCCACGCGTGCTTTCGGCGCTGCGGGTGAGCTTCGGCACCGCGTTTGCGGCCGGTGCC
TTCAACGCGGTGATGGGCACCTGGGTGGCATGGGTCTTCGTGCGCTACAGGTTTCCGGGCAAGCGCTTTTTCGATGCGGT
GATCGATTTGCCGTTCGCGTTGCCTACCGCGGTGGCCGGCATTGCGCTGACCGCGCTGTATGGCGGCAACGGGTGGGTGG
GACGCTGGCTGGAGGCGATCGGGATCAAGGTGGCCTACACGCAACTGGGTATCGTGCTGGCATTGGTCTTTGTGGGCCTG
CCCTTCGTGGTGCGGGTGGTGCAGCCGGTGCTGGCCGAGAGCGATCGTGAAATGGAGGCTGCCGCCGCCACACTGGGCGC
CTCGCGCTGGCAGACGGTCTGGCGGGTGGTGCTGCCGGGGGTGTGGCCGGCGGTCCTGACCGGGTTTGCGCTGGCGTTTG
CACGCGGCGTGGGGGAATACGGCTCGGTGATCTTCATTGCCGGCAACCTGCCCAATTCCACCGAGATCGCGCCGCTGCTG
ATCACCATCCGACTGGAAGAGTTCGACTACGCCGGCGCGACTGCCATTGCCGCGGCCATGCTGTTGCTGTCGTTCGTGAT
CTTGTTGGTGGTCAATACGCTGCAGGCACGGCTGCTGCGCTATCAACGCAGGCCCGTATGA

Upstream 100 bases:

>100_bases
GGTGACCATCCAGCAGGCGTTCGGCTCGTGGGAGAAGGCGCAGCAAGAGCATTTCGCCGACGGTGGCGTGTTCGACCAGA
TCCAGGCCAACAAGTAAGCG

Downstream 100 bases:

>100_bases
ACGATGCTGTTTCATCGCTGCCTTCCATGTTGCCGACCCATGCCATGACCAAGCAGGCGCGTCGCATCAGCGATTCGGCC
ACCAATGAGCCGCGTTGGGT

Product: ABC transporter sulfate permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MSMSVAPHPAPSSRRRVMPGLGLSLGITLTWLGLIVLIPLLGIFIKTSGLGWEGLWRVWSEPRVLSALRVSFGTAFAAGA
FNAVMGTWVAWVFVRYRFPGKRFFDAVIDLPFALPTAVAGIALTALYGGNGWVGRWLEAIGIKVAYTQLGIVLALVFVGL
PFVVRVVQPVLAESDREMEAAAATLGASRWQTVWRVVLPGVWPAVLTGFALAFARGVGEYGSVIFIAGNLPNSTEIAPLL
ITIRLEEFDYAGATAIAAAMLLLSFVILLVVNTLQARLLRYQRRPV

Sequences:

>Translated_286_residues
MSMSVAPHPAPSSRRRVMPGLGLSLGITLTWLGLIVLIPLLGIFIKTSGLGWEGLWRVWSEPRVLSALRVSFGTAFAAGA
FNAVMGTWVAWVFVRYRFPGKRFFDAVIDLPFALPTAVAGIALTALYGGNGWVGRWLEAIGIKVAYTQLGIVLALVFVGL
PFVVRVVQPVLAESDREMEAAAATLGASRWQTVWRVVLPGVWPAVLTGFALAFARGVGEYGSVIFIAGNLPNSTEIAPLL
ITIRLEEFDYAGATAIAAAMLLLSFVILLVVNTLQARLLRYQRRPV
>Mature_285_residues
SMSVAPHPAPSSRRRVMPGLGLSLGITLTWLGLIVLIPLLGIFIKTSGLGWEGLWRVWSEPRVLSALRVSFGTAFAAGAF
NAVMGTWVAWVFVRYRFPGKRFFDAVIDLPFALPTAVAGIALTALYGGNGWVGRWLEAIGIKVAYTQLGIVLALVFVGLP
FVVRVVQPVLAESDREMEAAAATLGASRWQTVWRVVLPGVWPAVLTGFALAFARGVGEYGSVIFIAGNLPNSTEIAPLLI
TIRLEEFDYAGATAIAAAMLLLSFVILLVVNTLQARLLRYQRRPV

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0555

COG function: function code O; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=268, Percent_Identity=50.3731343283582, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI87082099, Length=260, Percent_Identity=32.6923076923077, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786980, Length=159, Percent_Identity=38.3647798742138, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1787368, Length=234, Percent_Identity=28.2051282051282, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1786254, Length=224, Percent_Identity=27.6785714285714, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011865
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30921; Mature: 30790

Theoretical pI: Translated: 11.05; Mature: 11.05

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMSVAPHPAPSSRRRVMPGLGLSLGITLTWLGLIVLIPLLGIFIKTSGLGWEGLWRVWS
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
EPRVLSALRVSFGTAFAAGAFNAVMGTWVAWVFVRYRFPGKRFFDAVIDLPFALPTAVAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHH
IALTALYGGNGWVGRWLEAIGIKVAYTQLGIVLALVFVGLPFVVRVVQPVLAESDREMEA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AAATLGASRWQTVWRVVLPGVWPAVLTGFALAFARGVGEYGSVIFIAGNLPNSTEIAPLL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEE
ITIRLEEFDYAGATAIAAAMLLLSFVILLVVNTLQARLLRYQRRPV
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SMSVAPHPAPSSRRRVMPGLGLSLGITLTWLGLIVLIPLLGIFIKTSGLGWEGLWRVWS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
EPRVLSALRVSFGTAFAAGAFNAVMGTWVAWVFVRYRFPGKRFFDAVIDLPFALPTAVAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHH
IALTALYGGNGWVGRWLEAIGIKVAYTQLGIVLALVFVGLPFVVRVVQPVLAESDREMEA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AAATLGASRWQTVWRVVLPGVWPAVLTGFALAFARGVGEYGSVIFIAGNLPNSTEIAPLL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEE
ITIRLEEFDYAGATAIAAAMLLLSFVILLVVNTLQARLLRYQRRPV
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2188958; 9205837; 9278503; 2188959 [H]