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The map label for this gene is hemA [H]

Identifier: 21241715

GI number: 21241715

Start: 1107260

End: 1108540

Strand: Reverse

Name: hemA [H]

Synonym: XAC0945

Alternate gene names: 21241715

Gene position: 1108540-1107260 (Counterclockwise)

Preceding gene: 21241764

Following gene: 21241714

Centisome position: 21.42

GC content: 65.96

Gene sequence:

>1281_bases
ATGACGTTGTGGGTGCTCGGACTGAATCACCAGACCGCACCTGTGGACCTGCGCGAACGCGCGGCGTTCGCAGGTGATGC
GCTACCGCGCGCGCTCGAATCGCTGCGTGCGCTGCCCCAGGTGAGCGAGGCCGCGCTGCTGTCCACCTGCAACCGTACCG
AGTTGTATGCGATGGCCGAGGAGGCGCACAGCCTGGTCAACTGGCTGGAAACCCACGCGCCCGGCCTGAGCGGTTATCTG
TACCAGCACCAGGAAGCCGAGGCGGTGCGTCACCTGTTTCGTGTCGCCACCGGGCTGGATTCGATGGTATTGGGAGAACC
CCAGATTTTGGGCCAGGTGAAGGACGCCTGGGCAGTGGCGCGGGCGCACGGCGCGCTGGGCAGCGGGTTGGACCGGCTGT
TCCAACAGACCTTTTCGGTGGCCAAGCGTGCGCGTACCGACACCCGTGTCGGCGCAAATCCAGTGTCGGTCGCATCCACG
GCGGTGCGACTGGCACAGGACTCGTTTGCCCGGCTCAACGAATCCACGGTGCTGTTGATCGGTGCCGGCGAAACCATCGA
ACTGGCGGCCAAGCATCTGAGCGAAGGCCGCGTGCGCCGCCTGCTGATCGCCAACCGCACCCTGGCCCATGCACAGACAC
TGGCCAGCCAGCACGGCGGCTTCGCTTTGCCGCTGACCGATCTGGAACGCCACCTGGCCGAGGCCGACGTGGTGTTTTCG
GCCACCGCTGCGCGTGAGCCGCTGGTGACCCGCGTACAGGTGGAACAGGCCTTACGCGCCCGCAAGCGCAAACCGATGCT
GCTGTTCGACCTGGCGGTGCCGCGCGATATCGAGGCCTCGGTGGGCGAGTTGAGCGACGCCTACCTGTACACGGTGGACG
ACCTGGAACGTGCGGTCGAAGACAATCGCCGCGGGCGCCGCGAAGCGGCCGACCAGGCCGAAGCCATCATCGACCTGCAA
GTGGCGCGCTATGTCGAAACGCTGCAGGCCACTGCGCATCAGGCACCACTCAAGCGGCTGCGCGCGTTTGGCGATAGCAC
CCGCGACGAACTGCTGGCCAAGGCACGCCAGCAGTTGCACAACGGAAAACCGGCCGACGAAGTGCTGGAACAGTTGGCGC
ATGCGCTGACCAACCGCTTGCTGCATCCGCCCACCGCCGCACTGCGCGATGCGGCGCTCAACAACGACCTGGAATTGACC
GCTGCGGCCGACCGGCTGTTTCCGGAAAAGCCGGGTTACCAACATCCCCCCCATAGCTACCCCGATCGTGAGGACCGATG
A

Upstream 100 bases:

>100_bases
AAAAGAACACTCAGGATGCGAATCGGTACAGGCATCGGGGGCAACCGGGCCGTAAAATGGGGCCCTGAATGGCCGCCAGC
TTATCGCAAGCAACTGAACA

Downstream 100 bases:

>100_bases
CGCCGACCCTGCGCCGTAAGCTCCAAGCGCTGGCCGAGCGCCGCGAAGAACTGCAGCACCTGCTCTCCGACCCCGATGTG
GTGGGCAACAACGACACGTT

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MTLWVLGLNHQTAPVDLRERAAFAGDALPRALESLRALPQVSEAALLSTCNRTELYAMAEEAHSLVNWLETHAPGLSGYL
YQHQEAEAVRHLFRVATGLDSMVLGEPQILGQVKDAWAVARAHGALGSGLDRLFQQTFSVAKRARTDTRVGANPVSVAST
AVRLAQDSFARLNESTVLLIGAGETIELAAKHLSEGRVRRLLIANRTLAHAQTLASQHGGFALPLTDLERHLAEADVVFS
ATAAREPLVTRVQVEQALRARKRKPMLLFDLAVPRDIEASVGELSDAYLYTVDDLERAVEDNRRGRREAADQAEAIIDLQ
VARYVETLQATAHQAPLKRLRAFGDSTRDELLAKARQQLHNGKPADEVLEQLAHALTNRLLHPPTAALRDAALNNDLELT
AAADRLFPEKPGYQHPPHSYPDREDR

Sequences:

>Translated_426_residues
MTLWVLGLNHQTAPVDLRERAAFAGDALPRALESLRALPQVSEAALLSTCNRTELYAMAEEAHSLVNWLETHAPGLSGYL
YQHQEAEAVRHLFRVATGLDSMVLGEPQILGQVKDAWAVARAHGALGSGLDRLFQQTFSVAKRARTDTRVGANPVSVAST
AVRLAQDSFARLNESTVLLIGAGETIELAAKHLSEGRVRRLLIANRTLAHAQTLASQHGGFALPLTDLERHLAEADVVFS
ATAAREPLVTRVQVEQALRARKRKPMLLFDLAVPRDIEASVGELSDAYLYTVDDLERAVEDNRRGRREAADQAEAIIDLQ
VARYVETLQATAHQAPLKRLRAFGDSTRDELLAKARQQLHNGKPADEVLEQLAHALTNRLLHPPTAALRDAALNNDLELT
AAADRLFPEKPGYQHPPHSYPDREDR
>Mature_425_residues
TLWVLGLNHQTAPVDLRERAAFAGDALPRALESLRALPQVSEAALLSTCNRTELYAMAEEAHSLVNWLETHAPGLSGYLY
QHQEAEAVRHLFRVATGLDSMVLGEPQILGQVKDAWAVARAHGALGSGLDRLFQQTFSVAKRARTDTRVGANPVSVASTA
VRLAQDSFARLNESTVLLIGAGETIELAAKHLSEGRVRRLLIANRTLAHAQTLASQHGGFALPLTDLERHLAEADVVFSA
TAAREPLVTRVQVEQALRARKRKPMLLFDLAVPRDIEASVGELSDAYLYTVDDLERAVEDNRRGRREAADQAEAIIDLQV
ARYVETLQATAHQAPLKRLRAFGDSTRDELLAKARQQLHNGKPADEVLEQLAHALTNRLLHPPTAALRDAALNNDLELTA
AADRLFPEKPGYQHPPHSYPDREDR

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=406, Percent_Identity=47.7832512315271, Blast_Score=350, Evalue=8e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 46831; Mature: 46700

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLWVLGLNHQTAPVDLRERAAFAGDALPRALESLRALPQVSEAALLSTCNRTELYAMAE
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHH
EAHSLVNWLETHAPGLSGYLYQHQEAEAVRHLFRVATGLDSMVLGEPQILGQVKDAWAVA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHH
RAHGALGSGLDRLFQQTFSVAKRARTDTRVGANPVSVASTAVRLAQDSFARLNESTVLLI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
GAGETIELAAKHLSEGRVRRLLIANRTLAHAQTLASQHGGFALPLTDLERHLAEADVVFS
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHH
ATAAREPLVTRVQVEQALRARKRKPMLLFDLAVPRDIEASVGELSDAYLYTVDDLERAVE
HHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCHHEEEHHHHHHHHH
DNRRGRREAADQAEAIIDLQVARYVETLQATAHQAPLKRLRAFGDSTRDELLAKARQQLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
NGKPADEVLEQLAHALTNRLLHPPTAALRDAALNNDLELTAAADRLFPEKPGYQHPPHSY
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEHHHHHCCCCCCCCCCCCCCC
PDREDR
CCCCCC
>Mature Secondary Structure 
TLWVLGLNHQTAPVDLRERAAFAGDALPRALESLRALPQVSEAALLSTCNRTELYAMAE
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHH
EAHSLVNWLETHAPGLSGYLYQHQEAEAVRHLFRVATGLDSMVLGEPQILGQVKDAWAVA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHH
RAHGALGSGLDRLFQQTFSVAKRARTDTRVGANPVSVASTAVRLAQDSFARLNESTVLLI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
GAGETIELAAKHLSEGRVRRLLIANRTLAHAQTLASQHGGFALPLTDLERHLAEADVVFS
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHH
ATAAREPLVTRVQVEQALRARKRKPMLLFDLAVPRDIEASVGELSDAYLYTVDDLERAVE
HHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCHHEEEHHHHHHHHH
DNRRGRREAADQAEAIIDLQVARYVETLQATAHQAPLKRLRAFGDSTRDELLAKARQQLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
NGKPADEVLEQLAHALTNRLLHPPTAALRDAALNNDLELTAAADRLFPEKPGYQHPPHSY
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEHHHHHCCCCCCCCCCCCCCC
PDREDR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA