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The map label for this gene is kdgT

Identifier: 21241111

GI number: 21241111

Start: 402606

End: 403562

Strand: Reverse

Name: kdgT

Synonym: XAC0337

Alternate gene names: 21241111

Gene position: 403562-402606 (Counterclockwise)

Preceding gene: 21241112

Following gene: 21241107

Centisome position: 7.8

GC content: 68.55

Gene sequence:

>957_bases
ATGCGTATCAAGGCCACGGTGGAGCGGCTTCCCGGCGGGATGATGCTGGTCCCCTTGTTGCTCGGGGCGCTTTGCCACAC
GCTCTGGCCGCAGGCCGGCAGCACCTTGGGGTCTTTCAGCAACGGTCTGATCAGCGGCACGGTTCCGATCCTGGCGGTGT
GGTTTTTCTGCATGGGAGCAACCATCCAGCTGCGCGCCTCCGGACGGGTGCTGCGCCGTTCGGGCAGCTTGGTACTGACC
AAGATCGCGGTGGCCTGGCTCGTCGCAGTCCTGTGCGCACCGCTGCTTCCCATCGGCGGTGTGTCGAGCGGGCCGCTGGC
CGGGCTGTCGGTCCTGGCGCTGGTGGCTGCGATGGACATGACCAACGGCGGGCTGTACGCCGCGTTGATGCAGCAATACG
GCAGCAGCGAAGACGCAGGGGCAGTGGTGCTGATGTCGCTGGAATCGGGCCCGCTGATCTCCATGCTGATCCTGGGTGCC
AGCGGCCTGGCCAGCTTCGAACCACAGCTGTTCGTCGGGGCGGTGCTGCCGCTGTTGCTGGGCTTTGCACTGGGCAACCT
CGACGCGGAATTGCGGCAGTTCTTCGCGCAGGCGACCAAGACGCTGGTGCCTTTCTTCGGGTTCGCGCTCGGCAACACGC
TGGATCTGTCGACCATCGCCCACACCGGCACAAGTGGCGTGCTGCTGGGCGTGGCGGTCGTCGTGATCACCGGGCTGCCC
TTGCTGCTGGCCGACCGCTGGATCGGCGGCGGCAACGGCACCGCCGGGGTGGCCGCCTCCAGCACGGCCGGTGCCGCCGT
GGCCACTCCGGCCCTGATCGCCGGCATGGCGCCGCAGTTCGCACCCGCAGCGCCGGCCGCGACGGCGCTGGTGGCCAGTG
CGGTCATCGTCACCTCGTTGCTGGTGCCGCTGCTGACGGCCTTGTATGCACGCCGTGGCGATGCACGCAGCGGCTGA

Upstream 100 bases:

>100_bases
CGTGTGCGGCTGCGTGCGTTCGCGCCGGGATCTGCATGCACGCAGGTGCCTGCGCGATGCTGCCAGCCCCGCGCGTGGTG
ACGCGCTCACTGGAACGCGT

Downstream 100 bases:

>100_bases
GAGCCGGGCTGGCGCCATGCAGCCTGCGATGGGATGCCCGGGCCGTTGGCGTTGCGGCATGCATGGCGCCGGAACGAGTC
GGCGCCGGCGACGCCGGTGC

Product: 2-keto-3-deoxygluconate permease

Products: Proton [Cytoplasm]; 2-dehydro-3-deoxy-D-gluconate [Cytoplasm] [C]

Alternate protein names: KDG permease

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MRIKATVERLPGGMMLVPLLLGALCHTLWPQAGSTLGSFSNGLISGTVPILAVWFFCMGATIQLRASGRVLRRSGSLVLT
KIAVAWLVAVLCAPLLPIGGVSSGPLAGLSVLALVAAMDMTNGGLYAALMQQYGSSEDAGAVVLMSLESGPLISMLILGA
SGLASFEPQLFVGAVLPLLLGFALGNLDAELRQFFAQATKTLVPFFGFALGNTLDLSTIAHTGTSGVLLGVAVVVITGLP
LLLADRWIGGGNGTAGVAASSTAGAAVATPALIAGMAPQFAPAAPAATALVASAVIVTSLLVPLLTALYARRGDARSG

Sequences:

>Translated_318_residues
MRIKATVERLPGGMMLVPLLLGALCHTLWPQAGSTLGSFSNGLISGTVPILAVWFFCMGATIQLRASGRVLRRSGSLVLT
KIAVAWLVAVLCAPLLPIGGVSSGPLAGLSVLALVAAMDMTNGGLYAALMQQYGSSEDAGAVVLMSLESGPLISMLILGA
SGLASFEPQLFVGAVLPLLLGFALGNLDAELRQFFAQATKTLVPFFGFALGNTLDLSTIAHTGTSGVLLGVAVVVITGLP
LLLADRWIGGGNGTAGVAASSTAGAAVATPALIAGMAPQFAPAAPAATALVASAVIVTSLLVPLLTALYARRGDARSG
>Mature_318_residues
MRIKATVERLPGGMMLVPLLLGALCHTLWPQAGSTLGSFSNGLISGTVPILAVWFFCMGATIQLRASGRVLRRSGSLVLT
KIAVAWLVAVLCAPLLPIGGVSSGPLAGLSVLALVAAMDMTNGGLYAALMQQYGSSEDAGAVVLMSLESGPLISMLILGA
SGLASFEPQLFVGAVLPLLLGFALGNLDAELRQFFAQATKTLVPFFGFALGNTLDLSTIAHTGTSGVLLGVAVVVITGLP
LLLADRWIGGGNGTAGVAASSTAGAAVATPALIAGMAPQFAPAAPAATALVASAVIVTSLLVPLLTALYARRGDARSG

Specific function: The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdgT transporter family

Homologues:

Organism=Escherichia coli, GI87082349, Length=317, Percent_Identity=68.7697160883281, Blast_Score=411, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDGT_XANAC (Q8PQI6)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_640693.1
- GeneID:   1154408
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC0337
- NMPDR:   fig|190486.1.peg.337
- HOGENOM:   HBG322377
- OMA:   QLFVGAV
- ProtClustDB:   PRK05274
- BioCyc:   XAXO190486:XAC0337-MONOMER
- HAMAP:   MF_00070
- InterPro:   IPR004684
- InterPro:   IPR018395
- ProDom:   PD024513
- TIGRFAMs:   TIGR00793

Pfam domain/function: PF03812 KdgT

EC number: NA

Molecular weight: Translated: 31961; Mature: 31961

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb4de340)-; HASH(0x946b3c4)-; HASH(0xcc0a700)-; HASH(0xca0fb60)-; HASH(0xc372b6c)-; HASH(0xc2333e8)-; HASH(0xc934d58)-; HASH(0xcc17d54)-; HASH(0xc2f83f0)-; HASH(0xcbf8a24)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIKATVERLPGGMMLVPLLLGALCHTLWPQAGSTLGSFSNGLISGTVPILAVWFFCMGA
CCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHCHHHHHHHHHHHHCC
TIQLRASGRVLRRSGSLVLTKIAVAWLVAVLCAPLLPIGGVSSGPLAGLSVLALVAAMDM
CEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHC
TNGGLYAALMQQYGSSEDAGAVVLMSLESGPLISMLILGASGLASFEPQLFVGAVLPLLL
CCCHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
GFALGNLDAELRQFFAQATKTLVPFFGFALGNTLDLSTIAHTGTSGVLLGVAVVVITGLP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHCCH
LLLADRWIGGGNGTAGVAASSTAGAAVATPALIAGMAPQFAPAAPAATALVASAVIVTSL
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LVPLLTALYARRGDARSG
HHHHHHHHHHHCCCCCCH
>Mature Secondary Structure
MRIKATVERLPGGMMLVPLLLGALCHTLWPQAGSTLGSFSNGLISGTVPILAVWFFCMGA
CCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHCHHHHHHHHHHHHCC
TIQLRASGRVLRRSGSLVLTKIAVAWLVAVLCAPLLPIGGVSSGPLAGLSVLALVAAMDM
CEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHC
TNGGLYAALMQQYGSSEDAGAVVLMSLESGPLISMLILGASGLASFEPQLFVGAVLPLLL
CCCHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
GFALGNLDAELRQFFAQATKTLVPFFGFALGNTLDLSTIAHTGTSGVLLGVAVVVITGLP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHCCH
LLLADRWIGGGNGTAGVAASSTAGAAVATPALIAGMAPQFAPAAPAATALVASAVIVTSL
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LVPLLTALYARRGDARSG
HHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 2-dehydro-3-deoxy-D-gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 2-dehydro-3-deoxy-D-gluconate [Periplasm] = Proton [Cytoplasm] + 2-dehydro-3-deoxy-D-gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12024217