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The map label for this gene is yciC [H]

Identifier: 21241050

GI number: 21241050

Start: 329573

End: 330898

Strand: Direct

Name: yciC [H]

Synonym: XAC0276

Alternate gene names: 21241050

Gene position: 329573-330898 (Clockwise)

Preceding gene: 21241048

Following gene: 21241053

Centisome position: 6.37

GC content: 67.35

Gene sequence:

>1326_bases
ATGTCTCTGTCCCCCCAGCGCGATGCGCGCCTTCCCGTCACCGTGTTGTCCGGCTTTCTGGGTGCGGGCAAGACCACCTT
GCTCAATCGCATCCTGCACAACCGCGACGGCTTGCGGGTGGCGGTCATCGTCAACGACATGAGCGAGGTCAACATCGACG
CGCAGCTGGTTCGCGAGGGCGGCGCGGCGTTGCGGCGCACCGAAGAAACGCTGGTGGAATTCAGTAACGGCTGCATCTGC
TGCACGCTGCGCGACGATTTGCTGCAGGAAGTGCGGCGGCTGGCCGAGCAGGGCCGCTACGACTATCTGCTGATCGAATC
GACCGGTATTGCCGAGCCGATGCCGGTGGCGGCCACCTTCGCGGTGCGCGATGCCGATGGTTTCAGCCTATCGGACATCG
CTCGGCTCGACACCATGGTGACGGTGGTGGACGGCAGCCGTTTCCTGGAGGATTTCGGCTCGGCTGCCACGCTGGCCGAC
CTGGGCCAGCAAGCCGGCCCGGACGACACGCGCGGGCTGGTGCAGTTGCTGGGCGAACAGGTGGAGTTCGCCGATGTGCT
GGTGATCAGCAAGTGCGACCGCATCGACGCGCAGCAGCTGCAACGCCTTCGCGCCGTGCTGCGTGCGCTCAACCGCGACG
CGGCAATTGTGGATGCCGCGCACGGGGAAGTGCCGCTGCAGCAGCTGCTGGACACCGGGCGTTTCGATTTCACCCGTGCG
CAGCTGGCGCCGGGCTGGATGCAGGAACTGCGCGGCCAGCACACCCCCGAGACCGAGGAATACGGCATCAGCAGCTTCGT
GTACCGCGCGCGCCGGCCATTCCATCCACAGCGCTTCGCACGCATGGTGCACAGCGGCTTGCCGCAGGTGATCCGCAGCA
AGGGCTTCTTCTGGCTGGCCAGCCGCATGGATTGGGTGGGCGAACTGTCCAGCGTGGGCGGCGCCACCCAGACCAGCGCG
GCCGGGTTCTGGTTCGCTGCGCGCCACCGTGTCGATGCGCAGGCAGTCGGCCAGCCGCTGCAGACCAGCATCACGCCGCT
GCCCTACACCGATATCGGCTGGCAGCGGCAACAGACGCAGTGCTGGACCGCGCCACTGCCGCAACCGCACGAGGTCGGCG
ATGCCAGCGAATACGCTGCGATGCAGCGACTGTGGCATCCGCTCTGGGGCGATCGCCGCCAGGAGCTGGCGGTGATCGGC
GTGGACATGGATGCACCGCGCACACGGGCCGTGCTGGACGCGTGCCTGCTCAGCGATCAGGAACTACGGCAAGGGCCGGC
GCAATGGCAACTGCTGGACGACCCGTTCCCCCACTGGGCGCGGTAA

Upstream 100 bases:

>100_bases
GATGGCCGAGCTGTCCAGCAGGGAGGCGGTGGCGCGCATCAGAAGCATCCGGTCGAGTAAGTGTTATATAGTAACACTCC
TCTCTTGCCAGGCTCTCAGG

Downstream 100 bases:

>100_bases
CAGCGCACTGCAGCTGCTTGCCAAGCAAGTCGACGCCATCGCCAGCCTCATCGAGCTGGCGACGCTGCAGTTTGAGGTCA
GTGGCAACAGTGTCGTGGCT

Product: nitrile hydratase activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSLSPQRDARLPVTVLSGFLGAGKTTLLNRILHNRDGLRVAVIVNDMSEVNIDAQLVREGGAALRRTEETLVEFSNGCIC
CTLRDDLLQEVRRLAEQGRYDYLLIESTGIAEPMPVAATFAVRDADGFSLSDIARLDTMVTVVDGSRFLEDFGSAATLAD
LGQQAGPDDTRGLVQLLGEQVEFADVLVISKCDRIDAQQLQRLRAVLRALNRDAAIVDAAHGEVPLQQLLDTGRFDFTRA
QLAPGWMQELRGQHTPETEEYGISSFVYRARRPFHPQRFARMVHSGLPQVIRSKGFFWLASRMDWVGELSSVGGATQTSA
AGFWFAARHRVDAQAVGQPLQTSITPLPYTDIGWQRQQTQCWTAPLPQPHEVGDASEYAAMQRLWHPLWGDRRQELAVIG
VDMDAPRTRAVLDACLLSDQELRQGPAQWQLLDDPFPHWAR

Sequences:

>Translated_441_residues
MSLSPQRDARLPVTVLSGFLGAGKTTLLNRILHNRDGLRVAVIVNDMSEVNIDAQLVREGGAALRRTEETLVEFSNGCIC
CTLRDDLLQEVRRLAEQGRYDYLLIESTGIAEPMPVAATFAVRDADGFSLSDIARLDTMVTVVDGSRFLEDFGSAATLAD
LGQQAGPDDTRGLVQLLGEQVEFADVLVISKCDRIDAQQLQRLRAVLRALNRDAAIVDAAHGEVPLQQLLDTGRFDFTRA
QLAPGWMQELRGQHTPETEEYGISSFVYRARRPFHPQRFARMVHSGLPQVIRSKGFFWLASRMDWVGELSSVGGATQTSA
AGFWFAARHRVDAQAVGQPLQTSITPLPYTDIGWQRQQTQCWTAPLPQPHEVGDASEYAAMQRLWHPLWGDRRQELAVIG
VDMDAPRTRAVLDACLLSDQELRQGPAQWQLLDDPFPHWAR
>Mature_440_residues
SLSPQRDARLPVTVLSGFLGAGKTTLLNRILHNRDGLRVAVIVNDMSEVNIDAQLVREGGAALRRTEETLVEFSNGCICC
TLRDDLLQEVRRLAEQGRYDYLLIESTGIAEPMPVAATFAVRDADGFSLSDIARLDTMVTVVDGSRFLEDFGSAATLADL
GQQAGPDDTRGLVQLLGEQVEFADVLVISKCDRIDAQQLQRLRAVLRALNRDAAIVDAAHGEVPLQQLLDTGRFDFTRAQ
LAPGWMQELRGQHTPETEEYGISSFVYRARRPFHPQRFARMVHSGLPQVIRSKGFFWLASRMDWVGELSSVGGATQTSAA
GFWFAARHRVDAQAVGQPLQTSITPLPYTDIGWQRQQTQCWTAPLPQPHEVGDASEYAAMQRLWHPLWGDRRQELAVIGV
DMDAPRTRAVLDACLLSDQELRQGPAQWQLLDDPFPHWAR

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=261, Percent_Identity=34.4827586206897, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI126722884, Length=261, Percent_Identity=34.0996168582375, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI146231952, Length=261, Percent_Identity=34.0996168582375, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI148727351, Length=261, Percent_Identity=33.7164750957854, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI223941779, Length=240, Percent_Identity=34.5833333333333, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI223941776, Length=249, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI119120938, Length=146, Percent_Identity=39.7260273972603, Blast_Score=99, Evalue=6e-21,
Organism=Escherichia coli, GI87082430, Length=298, Percent_Identity=27.1812080536913, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788499, Length=275, Percent_Identity=26.1818181818182, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324356, Length=238, Percent_Identity=27.7310924369748, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 49080; Mature: 48949

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSPQRDARLPVTVLSGFLGAGKTTLLNRILHNRDGLRVAVIVNDMSEVNIDAQLVREG
CCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCHHHCCCHHHHHHHC
GAALRRTEETLVEFSNGCICCTLRDDLLQEVRRLAEQGRYDYLLIESTGIAEPMPVAATF
CHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEE
AVRDADGFSLSDIARLDTMVTVVDGSRFLEDFGSAATLADLGQQAGPDDTRGLVQLLGEQ
EEECCCCCCHHHHHHHHHHEEEECCHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHH
VEFADVLVISKCDRIDAQQLQRLRAVLRALNRDAAIVDAAHGEVPLQQLLDTGRFDFTRA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHCCCCCCCHHH
QLAPGWMQELRGQHTPETEEYGISSFVYRARRPFHPQRFARMVHSGLPQVIRSKGFFWLA
HCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHCCCCEEEH
SRMDWVGELSSVGGATQTSAAGFWFAARHRVDAQAVGQPLQTSITPLPYTDIGWQRQQTQ
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHCCCHHHCCCCCCCCCCCCCCCCCC
CWTAPLPQPHEVGDASEYAAMQRLWHPLWGDRRQELAVIGVDMDAPRTRAVLDACLLSDQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCH
ELRQGPAQWQLLDDPFPHWAR
HHHCCCCCEEECCCCCCCCCC
>Mature Secondary Structure 
SLSPQRDARLPVTVLSGFLGAGKTTLLNRILHNRDGLRVAVIVNDMSEVNIDAQLVREG
CCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCHHHCCCHHHHHHHC
GAALRRTEETLVEFSNGCICCTLRDDLLQEVRRLAEQGRYDYLLIESTGIAEPMPVAATF
CHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEE
AVRDADGFSLSDIARLDTMVTVVDGSRFLEDFGSAATLADLGQQAGPDDTRGLVQLLGEQ
EEECCCCCCHHHHHHHHHHEEEECCHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHH
VEFADVLVISKCDRIDAQQLQRLRAVLRALNRDAAIVDAAHGEVPLQQLLDTGRFDFTRA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHCCCCCCCHHH
QLAPGWMQELRGQHTPETEEYGISSFVYRARRPFHPQRFARMVHSGLPQVIRSKGFFWLA
HCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHCCCCEEEH
SRMDWVGELSSVGGATQTSAAGFWFAARHRVDAQAVGQPLQTSITPLPYTDIGWQRQQTQ
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHCCCHHHCCCCCCCCCCCCCCCCCC
CWTAPLPQPHEVGDASEYAAMQRLWHPLWGDRRQELAVIGVDMDAPRTRAVLDACLLSDQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCH
ELRQGPAQWQLLDDPFPHWAR
HHHCCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]