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The map label for this gene is cls [C]

Identifier: 21240969

GI number: 21240969

Start: 239550

End: 241568

Strand: Direct

Name: cls [C]

Synonym: XAC0195

Alternate gene names: 21240969

Gene position: 239550-241568 (Clockwise)

Preceding gene: 21240968

Following gene: 21240970

Centisome position: 4.63

GC content: 65.92

Gene sequence:

>2019_bases
GTGACGTATCTGTTGAGGGTTTGCGTGCTGGCAACGTTGTTGCTCGGCACCGGATGCGCCAGCCTGTCACAAACCGAACG
CAACCGTGCCGCCGGTGTCGCCGCTGCGGCACGCAGCACGGTGGTCAATTGCACCCAGGCCAATCGCTGTGCGCAACCCT
CGCCATTGCGCGCGCTGGGCGGCGAAGCGATCACCGCCTCCACACCAGGAGCGCCGCGGCATTACGCCACCATCGTCGAC
CATGGCGAAGAATCGCTGGTGGCCCGGCTCAACCTGATCCGCAGCGCCACCCGCAGCATCGATCTGCAGACCTACATTTT
CGATAAGGACGACAGCGCGCGCATGGTGCTGGACGCACTGGTGGACGCCGCCCAGCGCGGGGTCAAGGTGCGCATCCTGA
TCGATCAGTTGTCGGCGATCGCCGATCTGCAGATTCTCGGTGCGCTCGCCAGCAGCCATGAAAACCTGCAGCTGCGCATC
TACAACCCCACCTTCGGCAAGGTCAAGCTCAATTACTTCGATTATGCTGGCAGCGTGCTGTGTTGCTTCCGCCGCTTCAA
CCAGCGCATGCACAACAAGCTGCTGGTGGTGGACGACGTGCTGGGCGTGGTCGGTGGGCGCAATTACCAGGACGACTATT
ACGACTGGGACAGCGAGTACAACTTCCGCGACCGCGACGTGATTCTGGCCGGGCCGGAAGTGCGCGCCATGGCCGCCAAT
TTCGATGCGTTCTGGCGTGCCCGGCGCAGCGTACCGGCCGAGCGTCTGAACGATGTCGGGCGCCTGCTGCTGGAGCAGGG
CGTGCCGACGATGCCGCCGGCCGAGTTCCGCCGGCCCGACCGGGTGGCGCGAGTGGACCGCGAAGCGCACGACCCGCAAT
TCGTGCGCGACGCCTTCGTGACCCCGGCCATGCCGGTGAAGCGTGTGCTGTACGTGGCCGATCTGCCGCAAAAACACCGC
CGGGAACATGCGGCCAAGGCAGTGTCCACGGCGCCGGAACTGGATGGCCTGATTGCCGGCGCGCAGCAGGAAGTGCTGCT
GCAGACCCCCTACCTGGTCTTGTCCGACCAGGCGCAGGCGATCTTCCGCACGTTGCGCAAACACCCGCAGCCGCCGCGCA
TCGTGGTGTCGACCAATAGCCTGGCCGCCACCGACAACCCCATCGTGTATGCGCTGTCGTACAAGTTCAAACGCCGCAAC
ATGCGCGAGCTGGGCTTCAATGTGTACGAGTTCAAGCCGTTTCCGCTCGATGCCCCGGTGGATTACGCCAACCTGGTGAC
GGACCCGCTCAACCCCGCCTCCGACGTCAATCAGGACAGCCGCAACAATCGCCTGATCGGCGGCAGCGCAGCGGGCAATG
CGATGCGCGGCAGCAGCGGCCCGGAGGGCAACGCCAGCGCGAGCGCCGGCAGCGTGCTGCGCGGCAGTGGTGGCGGCCGT
GCGCCGGGCGGGAGCGAAGTCGATCGGCGCGTGTTGCGGACCGAAACGCGGCCCTCGTTCCTGGGCACGCGCGCGGTCAA
CAAGCCGCTGCCGGTGACCCGCGCCGGTGCGCGGATGGGCTTGCATGCCAAGTCGTTGGTGGTGGATCGCCGCATCGGCG
TGATCGGGACGCACAACTTCGACCCGCGCAGCGAAAACTACAACACCGAAGCGGCCGTGGTGATCGACGATGCGCGCTTT
GCGCAGGCGTTGGCTGCCAGCATCGAACGCGACATCGCTCCGGAAAATGCGTGGACGGTGGCGCCGCGCGAAAAGCCGCC
GGTGCTGAGCGGGTTGAACTACAGCGTGGGCAAGGTCTCCGAAGCCTTGCCGGTGCTGGACTTCTGGCCATGGCGCTACG
CCACCAACTACCAGTTCCAGCCCGGCCCGGATTGTCCGTTTCCGCTCAAGCGGCAGGACCCGCAGTTCCGCCAGTGCTAT
GTGGCGGTGGGCGATTTCCCGGAGGTCAATGTCGGCCCGAAGTGGCTGCTGGTGCGCATGCTGACCGCTTTCGGCGCCGG
GCTGGTACCGATTCTCTGA

Upstream 100 bases:

>100_bases
CGGTCCTGCGTGGACGTTACGGAATGAATGCGTGGCAGATGGCCCTGGGCGACAGGGTGACGTTCATTCTGCGTGGGCGC
TTGCAGGAGGCGCGGCGTCC

Downstream 100 bases:

>100_bases
TCGGCTGGCGTGCCACGCAGGTCGCAGCAGCGGATGCCTGACCGTGCAGCACGTTGTGGTTGGATGGACGCAGTTTGGCT
GCGGATCGGCTCCTGGACGC

Product: cardiolipin synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 672; Mature: 671

Protein sequence:

>672_residues
MTYLLRVCVLATLLLGTGCASLSQTERNRAAGVAAAARSTVVNCTQANRCAQPSPLRALGGEAITASTPGAPRHYATIVD
HGEESLVARLNLIRSATRSIDLQTYIFDKDDSARMVLDALVDAAQRGVKVRILIDQLSAIADLQILGALASSHENLQLRI
YNPTFGKVKLNYFDYAGSVLCCFRRFNQRMHNKLLVVDDVLGVVGGRNYQDDYYDWDSEYNFRDRDVILAGPEVRAMAAN
FDAFWRARRSVPAERLNDVGRLLLEQGVPTMPPAEFRRPDRVARVDREAHDPQFVRDAFVTPAMPVKRVLYVADLPQKHR
REHAAKAVSTAPELDGLIAGAQQEVLLQTPYLVLSDQAQAIFRTLRKHPQPPRIVVSTNSLAATDNPIVYALSYKFKRRN
MRELGFNVYEFKPFPLDAPVDYANLVTDPLNPASDVNQDSRNNRLIGGSAAGNAMRGSSGPEGNASASAGSVLRGSGGGR
APGGSEVDRRVLRTETRPSFLGTRAVNKPLPVTRAGARMGLHAKSLVVDRRIGVIGTHNFDPRSENYNTEAAVVIDDARF
AQALAASIERDIAPENAWTVAPREKPPVLSGLNYSVGKVSEALPVLDFWPWRYATNYQFQPGPDCPFPLKRQDPQFRQCY
VAVGDFPEVNVGPKWLLVRMLTAFGAGLVPIL

Sequences:

>Translated_672_residues
MTYLLRVCVLATLLLGTGCASLSQTERNRAAGVAAAARSTVVNCTQANRCAQPSPLRALGGEAITASTPGAPRHYATIVD
HGEESLVARLNLIRSATRSIDLQTYIFDKDDSARMVLDALVDAAQRGVKVRILIDQLSAIADLQILGALASSHENLQLRI
YNPTFGKVKLNYFDYAGSVLCCFRRFNQRMHNKLLVVDDVLGVVGGRNYQDDYYDWDSEYNFRDRDVILAGPEVRAMAAN
FDAFWRARRSVPAERLNDVGRLLLEQGVPTMPPAEFRRPDRVARVDREAHDPQFVRDAFVTPAMPVKRVLYVADLPQKHR
REHAAKAVSTAPELDGLIAGAQQEVLLQTPYLVLSDQAQAIFRTLRKHPQPPRIVVSTNSLAATDNPIVYALSYKFKRRN
MRELGFNVYEFKPFPLDAPVDYANLVTDPLNPASDVNQDSRNNRLIGGSAAGNAMRGSSGPEGNASASAGSVLRGSGGGR
APGGSEVDRRVLRTETRPSFLGTRAVNKPLPVTRAGARMGLHAKSLVVDRRIGVIGTHNFDPRSENYNTEAAVVIDDARF
AQALAASIERDIAPENAWTVAPREKPPVLSGLNYSVGKVSEALPVLDFWPWRYATNYQFQPGPDCPFPLKRQDPQFRQCY
VAVGDFPEVNVGPKWLLVRMLTAFGAGLVPIL
>Mature_671_residues
TYLLRVCVLATLLLGTGCASLSQTERNRAAGVAAAARSTVVNCTQANRCAQPSPLRALGGEAITASTPGAPRHYATIVDH
GEESLVARLNLIRSATRSIDLQTYIFDKDDSARMVLDALVDAAQRGVKVRILIDQLSAIADLQILGALASSHENLQLRIY
NPTFGKVKLNYFDYAGSVLCCFRRFNQRMHNKLLVVDDVLGVVGGRNYQDDYYDWDSEYNFRDRDVILAGPEVRAMAANF
DAFWRARRSVPAERLNDVGRLLLEQGVPTMPPAEFRRPDRVARVDREAHDPQFVRDAFVTPAMPVKRVLYVADLPQKHRR
EHAAKAVSTAPELDGLIAGAQQEVLLQTPYLVLSDQAQAIFRTLRKHPQPPRIVVSTNSLAATDNPIVYALSYKFKRRNM
RELGFNVYEFKPFPLDAPVDYANLVTDPLNPASDVNQDSRNNRLIGGSAAGNAMRGSSGPEGNASASAGSVLRGSGGGRA
PGGSEVDRRVLRTETRPSFLGTRAVNKPLPVTRAGARMGLHAKSLVVDRRIGVIGTHNFDPRSENYNTEAAVVIDDARFA
QALAASIERDIAPENAWTVAPREKPPVLSGLNYSVGKVSEALPVLDFWPWRYATNYQFQPGPDCPFPLKRQDPQFRQCYV
AVGDFPEVNVGPKWLLVRMLTAFGAGLVPIL

Specific function: Unknown

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI87081826, Length=334, Percent_Identity=30.8383233532934, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 73882; Mature: 73751

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYLLRVCVLATLLLGTGCASLSQTERNRAAGVAAAARSTVVNCTQANRCAQPSPLRALG
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECHHCCCCCCCCCHHHHC
GEAITASTPGAPRHYATIVDHGEESLVARLNLIRSATRSIDLQTYIFDKDDSARMVLDAL
CCEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHH
VDAAQRGVKVRILIDQLSAIADLQILGALASSHENLQLRIYNPTFGKVKLNYFDYAGSVL
HHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEHHHHHHH
CCFRRFNQRMHNKLLVVDDVLGVVGGRNYQDDYYDWDSEYNFRDRDVILAGPEVRAMAAN
HHHHHHHHHHHCCEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEHHC
FDAFWRARRSVPAERLNDVGRLLLEQGVPTMPPAEFRRPDRVARVDREAHDPQFVRDAFV
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHCCCHHHHHHHHC
TPAMPVKRVLYVADLPQKHRREHAAKAVSTAPELDGLIAGAQQEVLLQTPYLVLSDQAQA
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHEECCEEEECCCHHH
IFRTLRKHPQPPRIVVSTNSLAATDNPIVYALSYKFKRRNMRELGFNVYEFKPFPLDAPV
HHHHHHHCCCCCEEEEECCCEEECCCCEEEEEEEHHHHCCHHHHCCCEEEECCCCCCCCC
DYANLVTDPLNPASDVNQDSRNNRLIGGSAAGNAMRGSSGPEGNASASAGSVLRGSGGGR
CHHHHHCCCCCCHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
APGGSEVDRRVLRTETRPSFLGTRAVNKPLPVTRAGARMGLHAKSLVVDRRIGVIGTHNF
CCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCC
DPRSENYNTEAAVVIDDARFAQALAASIERDIAPENAWTVAPREKPPVLSGLNYSVGKVS
CCCCCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCHHHHH
EALPVLDFWPWRYATNYQFQPGPDCPFPLKRQDPQFRQCYVAVGDFPEVNVGPKWLLVRM
HHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHH
LTAFGAGLVPIL
HHHHCCCCCCCC
>Mature Secondary Structure 
TYLLRVCVLATLLLGTGCASLSQTERNRAAGVAAAARSTVVNCTQANRCAQPSPLRALG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECHHCCCCCCCCCHHHHC
GEAITASTPGAPRHYATIVDHGEESLVARLNLIRSATRSIDLQTYIFDKDDSARMVLDAL
CCEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHH
VDAAQRGVKVRILIDQLSAIADLQILGALASSHENLQLRIYNPTFGKVKLNYFDYAGSVL
HHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEHHHHHHH
CCFRRFNQRMHNKLLVVDDVLGVVGGRNYQDDYYDWDSEYNFRDRDVILAGPEVRAMAAN
HHHHHHHHHHHCCEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEHHC
FDAFWRARRSVPAERLNDVGRLLLEQGVPTMPPAEFRRPDRVARVDREAHDPQFVRDAFV
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHCCCHHHHHHHHC
TPAMPVKRVLYVADLPQKHRREHAAKAVSTAPELDGLIAGAQQEVLLQTPYLVLSDQAQA
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHEECCEEEECCCHHH
IFRTLRKHPQPPRIVVSTNSLAATDNPIVYALSYKFKRRNMRELGFNVYEFKPFPLDAPV
HHHHHHHCCCCCEEEEECCCEEECCCCEEEEEEEHHHHCCHHHHCCCEEEECCCCCCCCC
DYANLVTDPLNPASDVNQDSRNNRLIGGSAAGNAMRGSSGPEGNASASAGSVLRGSGGGR
CHHHHHCCCCCCHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
APGGSEVDRRVLRTETRPSFLGTRAVNKPLPVTRAGARMGLHAKSLVVDRRIGVIGTHNF
CCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCC
DPRSENYNTEAAVVIDDARFAQALAASIERDIAPENAWTVAPREKPPVLSGLNYSVGKVS
CCCCCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCHHHHH
EALPVLDFWPWRYATNYQFQPGPDCPFPLKRQDPQFRQCYVAVGDFPEVNVGPKWLLVRM
HHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHH
LTAFGAGLVPIL
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]