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The map label for this gene is hsdM [C]

Identifier: 21228806

GI number: 21228806

Start: 3231501

End: 3232925

Strand: Reverse

Name: hsdM [C]

Synonym: MM_2704

Alternate gene names: 21228806

Gene position: 3232925-3231501 (Counterclockwise)

Preceding gene: 21228807

Following gene: 21228805

Centisome position: 78.92

GC content: 49.68

Gene sequence:

>1425_bases
ATGAGTGATATTGTACAGAAATTATGGGGTTTTTGCCACACTTTACGGCATGAAGGTATCGATTACGGCGATTATATCGA
ACAAATTACATACCTGCTTTTTTTAAAAATGGCTGACGAGCGGGAAATTAAACTTCCTGAAGCCTGCGACTGGCAGTCCC
TGAAAGAAAAATCAGGAACCGAACTCACAGAGCATTATAACGATGCACTTCGGACACTTGGTAAGCAGGAAGAGCTCCTT
GGTGATATATTTGCAGGCGCTCTTTCTCGTTTTCACAACCCTGTGAGCCTTAAGAAGATTATTTCCCTTATCGATGAAAC
CGAATGGACAGGCCTTGATATCGATGTCAAAGCAATGGCTTTTGAGGGCCTCCTTGAAAAAGCGGCAAGCGAAGGAAAGA
AAGGTGCAGGTCAGTATTTCACTCCAAGGATTGTGATCCAGACAATTGTAAGATGCACAAAACCCGACCCCCGAAACCAC
CGTGATTTTTCAATTATGGACCCTGCATGTGGGACCGGCGGTTTTCTGGTCTGCGCCTATGAATGGCTGAAAGCTGTAAC
CGGAGGCGGAGCCCTTGAGCGCGACCTTGCAAAAAAAATCCGCTACAGCACCTATTTCGGGCAGGAACTTGTGGAACGCC
CGCGCAGGCTTGCCCTTATGAACCTCTACCTTCACGGTATCGAGCCTGAAATCAAGCTCGGAGATTCCATCTATGAAATC
CCGGAATCAAAAAAGTTCGATGTGGTACTCACCAACCCACCCTTCGGGACAAAAGGCGCAAACCAGGCCCCTGTCCGTGA
AGATTTCGTTATCGAAACCTCAAACAAGCAGCTAAATTTCATCCAGCACGTAATGACAATCTTGAAACCCGGCGGCAGAG
CTGCAATCGTAGTCCCTGACAACGTGCTTTTTGCAGACCAGGCAGGAGAGGTTTTCAAGGTGCTCTGCGAAGACTGCGAC
CTGCACACGGTCCTGCGGCTTCCGGACGGCACATTCACGCCCTATTCCCCGGGCACGAAAACCAATGTGATATTTTTTAC
GAAAGGCATCCCCACAGACCGGACCTGGGTCTACGACTGCCGGACCAATGTCCCGAAGATCACGAAAAAGGACCGCCCGC
TCACAAAAGAGCATTTTGCGGAGTTTGAAAAGTGCTTCGGTTCCGATCCCAACGGCAGGGCAAAACGCGAGGAAAAAGAT
TCCCAGGAAGACCGCTGGCGCAGTTTCCATATCTCCGAACTCAAAGCCCGCGACTACAAGATTGATTCCCTGAAGTGGCT
CAGGGACGATTCCTTAAGCGACACCGACGACCTGCCCGATCCTGAAGAGCTTGCAGCAGAGGCAATTGATGAGCTTGAAG
CGGCGCTGGGTGAGTTAAATGCTATTCTTGATTTGATGGGGAATGGGTATGCAGCAGAAGAGTGA

Upstream 100 bases:

>100_bases
TTCCCGTGTTTTCCGATTACGGCGGCTGGAATAAAGCTAACCGTGTTTTTGAAGGCAAGCTTTCTACTTTGATTTCAGAA
TTTAACAGGGCAGTTGCAGC

Downstream 100 bases:

>100_bases
ACTGCCAGAAGGGTGGGCTGAATGTCAAATAAAAGACATAGTGGTAATTAATTATGGGAAGGGTTTAAAAAAAAGCGATA
GGGTAGAAGGTCAGTTTGAT

Product: type I restriction-modification system specificity subunit

Products: NA

Alternate protein names: M.BthVORF4518P [H]

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MSDIVQKLWGFCHTLRHEGIDYGDYIEQITYLLFLKMADEREIKLPEACDWQSLKEKSGTELTEHYNDALRTLGKQEELL
GDIFAGALSRFHNPVSLKKIISLIDETEWTGLDIDVKAMAFEGLLEKAASEGKKGAGQYFTPRIVIQTIVRCTKPDPRNH
RDFSIMDPACGTGGFLVCAYEWLKAVTGGGALERDLAKKIRYSTYFGQELVERPRRLALMNLYLHGIEPEIKLGDSIYEI
PESKKFDVVLTNPPFGTKGANQAPVREDFVIETSNKQLNFIQHVMTILKPGGRAAIVVPDNVLFADQAGEVFKVLCEDCD
LHTVLRLPDGTFTPYSPGTKTNVIFFTKGIPTDRTWVYDCRTNVPKITKKDRPLTKEHFAEFEKCFGSDPNGRAKREEKD
SQEDRWRSFHISELKARDYKIDSLKWLRDDSLSDTDDLPDPEELAAEAIDELEAALGELNAILDLMGNGYAAEE

Sequences:

>Translated_474_residues
MSDIVQKLWGFCHTLRHEGIDYGDYIEQITYLLFLKMADEREIKLPEACDWQSLKEKSGTELTEHYNDALRTLGKQEELL
GDIFAGALSRFHNPVSLKKIISLIDETEWTGLDIDVKAMAFEGLLEKAASEGKKGAGQYFTPRIVIQTIVRCTKPDPRNH
RDFSIMDPACGTGGFLVCAYEWLKAVTGGGALERDLAKKIRYSTYFGQELVERPRRLALMNLYLHGIEPEIKLGDSIYEI
PESKKFDVVLTNPPFGTKGANQAPVREDFVIETSNKQLNFIQHVMTILKPGGRAAIVVPDNVLFADQAGEVFKVLCEDCD
LHTVLRLPDGTFTPYSPGTKTNVIFFTKGIPTDRTWVYDCRTNVPKITKKDRPLTKEHFAEFEKCFGSDPNGRAKREEKD
SQEDRWRSFHISELKARDYKIDSLKWLRDDSLSDTDDLPDPEELAAEAIDELEAALGELNAILDLMGNGYAAEE
>Mature_473_residues
SDIVQKLWGFCHTLRHEGIDYGDYIEQITYLLFLKMADEREIKLPEACDWQSLKEKSGTELTEHYNDALRTLGKQEELLG
DIFAGALSRFHNPVSLKKIISLIDETEWTGLDIDVKAMAFEGLLEKAASEGKKGAGQYFTPRIVIQTIVRCTKPDPRNHR
DFSIMDPACGTGGFLVCAYEWLKAVTGGGALERDLAKKIRYSTYFGQELVERPRRLALMNLYLHGIEPEIKLGDSIYEIP
ESKKFDVVLTNPPFGTKGANQAPVREDFVIETSNKQLNFIQHVMTILKPGGRAAIVVPDNVLFADQAGEVFKVLCEDCDL
HTVLRLPDGTFTPYSPGTKTNVIFFTKGIPTDRTWVYDCRTNVPKITKKDRPLTKEHFAEFEKCFGSDPNGRAKREEKDS
QEDRWRSFHISELKARDYKIDSLKWLRDDSLSDTDDLPDPEELAAEAIDELEAALGELNAILDLMGNGYAAEE

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=516, Percent_Identity=40.3100775193798, Blast_Score=322, Evalue=3e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 53584; Mature: 53453

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIVQKLWGFCHTLRHEGIDYGDYIEQITYLLFLKMADEREIKLPEACDWQSLKEKSGT
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCC
ELTEHYNDALRTLGKQEELLGDIFAGALSRFHNPVSLKKIISLIDETEWTGLDIDVKAMA
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEHHHHH
FEGLLEKAASEGKKGAGQYFTPRIVIQTIVRCTKPDPRNHRDFSIMDPACGTGGFLVCAY
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHHH
EWLKAVTGGGALERDLAKKIRYSTYFGQELVERPRRLALMNLYLHGIEPEIKLGDSIYEI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHC
PESKKFDVVLTNPPFGTKGANQAPVREDFVIETSNKQLNFIQHVMTILKPGGRAAIVVPD
CCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEECC
NVLFADQAGEVFKVLCEDCDLHTVLRLPDGTFTPYSPGTKTNVIFFTKGIPTDRTWVYDC
CEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEC
RTNVPKITKKDRPLTKEHFAEFEKCFGSDPNGRAKREEKDSQEDRWRSFHISELKARDYK
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCC
IDSLKWLRDDSLSDTDDLPDPEELAAEAIDELEAALGELNAILDLMGNGYAAEE
CCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SDIVQKLWGFCHTLRHEGIDYGDYIEQITYLLFLKMADEREIKLPEACDWQSLKEKSGT
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCC
ELTEHYNDALRTLGKQEELLGDIFAGALSRFHNPVSLKKIISLIDETEWTGLDIDVKAMA
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEHHHHH
FEGLLEKAASEGKKGAGQYFTPRIVIQTIVRCTKPDPRNHRDFSIMDPACGTGGFLVCAY
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHHH
EWLKAVTGGGALERDLAKKIRYSTYFGQELVERPRRLALMNLYLHGIEPEIKLGDSIYEI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHC
PESKKFDVVLTNPPFGTKGANQAPVREDFVIETSNKQLNFIQHVMTILKPGGRAAIVVPD
CCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEECC
NVLFADQAGEVFKVLCEDCDLHTVLRLPDGTFTPYSPGTKTNVIFFTKGIPTDRTWVYDC
CEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEC
RTNVPKITKKDRPLTKEHFAEFEKCFGSDPNGRAKREEKDSQEDRWRSFHISELKARDYK
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCC
IDSLKWLRDDSLSDTDDLPDPEELAAEAIDELEAALGELNAILDLMGNGYAAEE
CCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]