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The map label for this gene is 21228137

Identifier: 21228137

GI number: 21228137

Start: 2433231

End: 2433845

Strand: Reverse

Name: 21228137

Synonym: MM_2035

Alternate gene names: NA

Gene position: 2433845-2433231 (Counterclockwise)

Preceding gene: 21228138

Following gene: 21228135

Centisome position: 59.42

GC content: 48.62

Gene sequence:

>615_bases
ATGAAGAATATAGAAGATCTCATTCAGAAAGCTGTGGAACTTCAGAACAACGGGCTTGGAACCGGCCAGATTGCCGATGA
GCTTAACGTATCAAGAGAAACAGTTACATGGCTTTTAACCCGTTCGAAAAAAGAAGTCGCAGCTCCCGCTCCAAAAGACA
TATCCGTAAACTGGAGCAGCATAGGAAAGAGCGCTACACGGCTTCACTACATTTCGCTTGCACTCTGCGATATGGTGATT
GAGACGCTGGAAAAAACAAACACCGAGGTGGATGTGGTAGTTGGTGTTGCAGCGAGTGGAATTCCACTGGCAAGCATGAT
GGCAAATGAGCTGGGGGCAGATTTTGCCCTTTACCATTCCCGTAAAGGACAGGACATGGTCCAGCCAGGCCAGAAAGGCA
CCATCAGCAGGAACTTCGGAAGCGTTGCAGGCAAAAACTGTGTAATCGTTGACGATGTAATTACCACAGGTTCGACCACA
ATGGAAGTAATCGAGCAGCTGCGTGAAATGGACGCAAAACCCAGAGCAGTGGTGGTTCTTGTGGACAAGAAAGGTGCGGA
TACAATCGCCAATGTTCCTATCCAGTCCCTTGTAAGGATAGTGCGCGTGGACTGA

Upstream 100 bases:

>100_bases
AAAATTTTTCGGGCAGTAATTCCAGGCAGTATTCATAAGAAGAACTGCAAAATCGGCCGGAAATACAGCCAGATAAAAAA
TTTCAGGTGGGAATGGAGGC

Downstream 100 bases:

>100_bases
AAAGACAGAAAAGATGAAACAGAAGCAATCTTTTTTACTGGAGAGCCTTTCTCAGGAAGGGTTTTTCCAGAACTTACATT
TATTTTATACTTGCTTTTTT

Product: orotate phosphoribosyltransferase-like protein

Products: orotate; 5-phospho-alpha-D-ribose 1-diphosphate

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MKNIEDLIQKAVELQNNGLGTGQIADELNVSRETVTWLLTRSKKEVAAPAPKDISVNWSSIGKSATRLHYISLALCDMVI
ETLEKTNTEVDVVVGVAASGIPLASMMANELGADFALYHSRKGQDMVQPGQKGTISRNFGSVAGKNCVIVDDVITTGSTT
MEVIEQLREMDAKPRAVVVLVDKKGADTIANVPIQSLVRIVRVD

Sequences:

>Translated_204_residues
MKNIEDLIQKAVELQNNGLGTGQIADELNVSRETVTWLLTRSKKEVAAPAPKDISVNWSSIGKSATRLHYISLALCDMVI
ETLEKTNTEVDVVVGVAASGIPLASMMANELGADFALYHSRKGQDMVQPGQKGTISRNFGSVAGKNCVIVDDVITTGSTT
MEVIEQLREMDAKPRAVVVLVDKKGADTIANVPIQSLVRIVRVD
>Mature_204_residues
MKNIEDLIQKAVELQNNGLGTGQIADELNVSRETVTWLLTRSKKEVAAPAPKDISVNWSSIGKSATRLHYISLALCDMVI
ETLEKTNTEVDVVVGVAASGIPLASMMANELGADFALYHSRKGQDMVQPGQKGTISRNFGSVAGKNCVIVDDVITTGSTT
MEVIEQLREMDAKPRAVVVLVDKKGADTIANVPIQSLVRIVRVD

Specific function: Unknown

COG id: COG0856

COG function: function code F; Orotate phosphoribosyltransferase homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005854
- InterPro:   IPR022854
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: 2.4.2.10

Molecular weight: Translated: 21976; Mature: 21976

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIEDLIQKAVELQNNGLGTGQIADELNVSRETVTWLLTRSKKEVAAPAPKDISVNWSS
CCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHCCCHHHCCCCCCCCEEEHHH
IGKSATRLHYISLALCDMVIETLEKTNTEVDVVVGVAASGIPLASMMANELGADFALYHS
HCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEHCC
RKGQDMVQPGQKGTISRNFGSVAGKNCVIVDDVITTGSTTMEVIEQLREMDAKPRAVVVL
CCCCHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEE
VDKKGADTIANVPIQSLVRIVRVD
EECCCCCHHHCCCHHHHHHHHCCC
>Mature Secondary Structure
MKNIEDLIQKAVELQNNGLGTGQIADELNVSRETVTWLLTRSKKEVAAPAPKDISVNWSS
CCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHCCCHHHCCCCCCCCEEEHHH
IGKSATRLHYISLALCDMVIETLEKTNTEVDVVVGVAASGIPLASMMANELGADFALYHS
HCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEHCC
RKGQDMVQPGQKGTISRNFGSVAGKNCVIVDDVITTGSTTMEVIEQLREMDAKPRAVVVL
CCCCHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEE
VDKKGADTIANVPIQSLVRIVRVD
EECCCCCHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: orotidine 5'-phosphate; diphosphate

Specific reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]