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The map label for this gene is 21227718

Identifier: 21227718

GI number: 21227718

Start: 1927818

End: 1928630

Strand: Direct

Name: 21227718

Synonym: MM_1616

Alternate gene names: NA

Gene position: 1927818-1928630 (Clockwise)

Preceding gene: 21227717

Following gene: 21227719

Centisome position: 47.06

GC content: 50.68

Gene sequence:

>813_bases
ATGGATCTTAATGATATATTGAAGGCTGTTAAAGAAGGGAAAATCGACCTCGAAACTGCGGAACAGCATGTCCGGAGTCT
GGGTTTTGTCAGTTATTCTAACATAGCTAAAGTGGATACTCACAGGAAAACAAGGACCGGTGTAATAGAGGCGATTCTTG
CTGACTGCAAGGAGCCTGAGGATGTTGTCGAGATTGCCAGGGTTATGGTAGAAAAAAGTAAAAGAGCCCTGGTTACCCGT
GCGTCTACATCACATGTGGAAGCCTTAATGAAAGCTTTTGGTGATGATAAACTCGAATGGAACAGCCGGGCACGTACGGT
GGTTGTTCACGACGGGACTCCGGCTCCACGCACAGGAGGAGTTGTTGGAGTCATATCCGCAGGCACGGCAGACATCCCTG
CTGCAGAAGAGGCAAGGACTATTGCTTCCGAAATGGGCTGCGAAACCATTGCTGTGTATGATGTAGGCGTTGCCGGGATC
CACAGGCTGATCCCTGAACTCCAGAAGCTCAAGCTCCGGAACCCCGGCGCGATTGTTGTTGCAGCCGGAAGAGAAGGAAC
ACTTCCGACCATAGTCTCAGGGCTTGTTGATGTACCGGTAATAGGGCTTCCGGTATCTACAGGTTACGGGGCAGGCGGCG
GTGGAAAAGCGGCTCTTCTGTCAATGCTTCAGTCCTGCTCGACCCTTGCAGTGGTAAATATCGATGCTGGATTCGTTGCA
GGGGCTTATGCGGCAAGGATTGCCAATATGATTGCTGCTGCCGGAGAAGGGAAAATAACTGAAGAAACGGAACAGGAAGA
AACCGGAGAGTAA

Upstream 100 bases:

>100_bases
AAACTCTAAAAAGCCTCCAAACCAATAATTATTGCCTGATAATTTGATATTTAAGCTGTTTATTGTTAGAGCATTCAATT
CTTCTGATTAAGGGTGGTGC

Downstream 100 bases:

>100_bases
TAATATCTTGAAAACGACGAACGAGGACGGGTTCAAAAGTAAAATTCAGGGAGGTAATTTATGAAATCACTGGTCTTTAA
CCCTTTTTCAGGTGCAGCCG

Product: phosphoribosylaminoimidazole carboxylase

Products: 5-amino-1-(5-phospho-D-ribosyl)imidazole; CO2

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MDLNDILKAVKEGKIDLETAEQHVRSLGFVSYSNIAKVDTHRKTRTGVIEAILADCKEPEDVVEIARVMVEKSKRALVTR
ASTSHVEALMKAFGDDKLEWNSRARTVVVHDGTPAPRTGGVVGVISAGTADIPAAEEARTIASEMGCETIAVYDVGVAGI
HRLIPELQKLKLRNPGAIVVAAGREGTLPTIVSGLVDVPVIGLPVSTGYGAGGGGKAALLSMLQSCSTLAVVNIDAGFVA
GAYAARIANMIAAAGEGKITEETEQEETGE

Sequences:

>Translated_270_residues
MDLNDILKAVKEGKIDLETAEQHVRSLGFVSYSNIAKVDTHRKTRTGVIEAILADCKEPEDVVEIARVMVEKSKRALVTR
ASTSHVEALMKAFGDDKLEWNSRARTVVVHDGTPAPRTGGVVGVISAGTADIPAAEEARTIASEMGCETIAVYDVGVAGI
HRLIPELQKLKLRNPGAIVVAAGREGTLPTIVSGLVDVPVIGLPVSTGYGAGGGGKAALLSMLQSCSTLAVVNIDAGFVA
GAYAARIANMIAAAGEGKITEETEQEETGE
>Mature_270_residues
MDLNDILKAVKEGKIDLETAEQHVRSLGFVSYSNIAKVDTHRKTRTGVIEAILADCKEPEDVVEIARVMVEKSKRALVTR
ASTSHVEALMKAFGDDKLEWNSRARTVVVHDGTPAPRTGGVVGVISAGTADIPAAEEARTIASEMGCETIAVYDVGVAGI
HRLIPELQKLKLRNPGAIVVAAGREGTLPTIVSGLVDVPVIGLPVSTGYGAGGGGKAALLSMLQSCSTLAVVNIDAGFVA
GAYAARIANMIAAAGEGKITEETEQEETGE

Specific function: Unknown

COG id: COG1691

COG function: function code R; NCAIR mutase (PurE)-related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: 4.1.1.21

Molecular weight: Translated: 28170; Mature: 28170

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNDILKAVKEGKIDLETAEQHVRSLGFVSYSNIAKVDTHRKTRTGVIEAILADCKEPE
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCHH
DVVEIARVMVEKSKRALVTRASTSHVEALMKAFGDDKLEWNSRARTVVVHDGTPAPRTGG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCCC
VVGVISAGTADIPAAEEARTIASEMGCETIAVYDVGVAGIHRLIPELQKLKLRNPGAIVV
EEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEE
AAGREGTLPTIVSGLVDVPVIGLPVSTGYGAGGGGKAALLSMLQSCSTLAVVNIDAGFVA
ECCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCHHH
GAYAARIANMIAAAGEGKITEETEQEETGE
HHHHHHHHHHHHHCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MDLNDILKAVKEGKIDLETAEQHVRSLGFVSYSNIAKVDTHRKTRTGVIEAILADCKEPE
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCHH
DVVEIARVMVEKSKRALVTRASTSHVEALMKAFGDDKLEWNSRARTVVVHDGTPAPRTGG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCCC
VVGVISAGTADIPAAEEARTIASEMGCETIAVYDVGVAGIHRLIPELQKLKLRNPGAIVV
EEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEE
AAGREGTLPTIVSGLVDVPVIGLPVSTGYGAGGGGKAALLSMLQSCSTLAVVNIDAGFVA
ECCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCHHH
GAYAARIANMIAAAGEGKITEETEQEETGE
HHHHHHHHHHHHHCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

Specific reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]