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The map label for this gene is gntP [H]

Identifier: 21227433

GI number: 21227433

Start: 1588402

End: 1589739

Strand: Direct

Name: gntP [H]

Synonym: MM_1331

Alternate gene names: 21227433

Gene position: 1588402-1589739 (Clockwise)

Preceding gene: 21227432

Following gene: 21227434

Centisome position: 38.78

GC content: 44.39

Gene sequence:

>1338_bases
ATGCATCCTGTCCTCATTTTCCTTTTCGCACTTATAGCCATACTGCTTTTTACGGCAAAATTCAGGCTTCACCCTTTCCT
TAGTCTTGTTCTTGTATCTCTTCTAACAGGGATTCTTGCAGGAGAGCCCATACGCACTATCGAAGCAGTTACTGAAGGAC
TGGGAAGCGTTTTTTCCCGTTTTGCCATTATTATTACGAGTGGGAGCATCATCGGACTTCTGCTCCAGAAAACCGGGGGA
ATGTCTTTAATAGCTTCTGACATTACGCGCTTTTTCAAAAATCCCCTGCTTGCCCTGAGCTTTCTTGGATTTCTTTTTTC
CGTGCCAACAATGTGCTATATCCTTGCTTACGTTATCTTTATCCCGATAGCAAAAGAACTGTCTTCCAGGTTCAATTACC
CCCCGATTTCCACTGCAACTGCACTTGCATTGGGAGCCGTTGCTTCATTTAATCTGGTTTATCCTTCCCCTGTGATCATT
TCGGCAGCAGAAGAACTTTCAGCAAACAGGGATATGCTTATTCTACTGGGATTTCTTACCGCTGTTCCCACTTCTTTTTC
AGGATATCTTTATGCGAGGAGTCTTGGAAAGGCTGAAGTTTCCGGAATGAATGAGGGTGGGGTAATACGGGAAAAAACCA
TTGTAAAGGAGAAAAAAGACCTGTCACAGGAAAATGGTGCGTTGCAAAGGACAGAAAATAGAAAACCAGGAAGGTTTGAA
GCTTATGCTCCGATTTTTATTCCTCTATTTCTCATCCTTTTCGAGGCTGTATTAAATAATCCTAATACTCTATTCACCTT
TCTGGGAAATCCGAATGTTGCATTACTTATTGGGGTCCTTCTTTCTATTTTTTCCGGGAGAGTGCTGGGACTTCCAATGA
TAAGGGTCCAGGTCGAAAAAGCCATAAAAAGAAGCGGTGTTGTCCTGCTCGACCTTTGTGGGGGTGGAGCTCTTGGTGCA
ACTCTTGCCATGACAGGAGCAGGGGAAGCCCTTGGAAAGTTTTTCCTGCAGTTCAACCTGCCTCATATTCTTGTGCCTTT
TCTTGTTGCAGCAGCCCTCCAAACAGTGCAGGGCTCAAGAGTTGTAACGATGCTCGTCGCTCCGTCCCTTTTACTCCCCC
TTGTCCCTGAGCTTGGACTCCCTCCGGAAATTTTGATCCTTTCAATGGCTTCAGGCACTTTTATGATTTCACACGTTAAT
GACCCGTTTTTCTGGATTTTCGGAGAACTCGCAGAACTGACACCCTCTGAGGTTTTCAGGTCAAATACACTTGGAAACGC
CCTTATGGGAGTAGTAAGCTTTCTGATCGTCTCCGGAATATATTTTTTCTTTTACTGA

Upstream 100 bases:

>100_bases
GGAATCTCCGGAGGAGAACACTTAAGAGTCTATAAGTAAGATATACCGGGATTCATTTCCCATTATCAGCAATTTATAAT
TCCATAAGAGCCGGAATATG

Downstream 100 bases:

>100_bases
TATTTTTTAAAGAATTTTATATCTTATTTGTAGTATTAGATATTTTTTAATAATTAATTTTTATGCTATGTGTTTTCTTT
TACATTATATTTTCATTTAT

Product: gluconate permease

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MHPVLIFLFALIAILLFTAKFRLHPFLSLVLVSLLTGILAGEPIRTIEAVTEGLGSVFSRFAIIITSGSIIGLLLQKTGG
MSLIASDITRFFKNPLLALSFLGFLFSVPTMCYILAYVIFIPIAKELSSRFNYPPISTATALALGAVASFNLVYPSPVII
SAAEELSANRDMLILLGFLTAVPTSFSGYLYARSLGKAEVSGMNEGGVIREKTIVKEKKDLSQENGALQRTENRKPGRFE
AYAPIFIPLFLILFEAVLNNPNTLFTFLGNPNVALLIGVLLSIFSGRVLGLPMIRVQVEKAIKRSGVVLLDLCGGGALGA
TLAMTGAGEALGKFFLQFNLPHILVPFLVAAALQTVQGSRVVTMLVAPSLLLPLVPELGLPPEILILSMASGTFMISHVN
DPFFWIFGELAELTPSEVFRSNTLGNALMGVVSFLIVSGIYFFFY

Sequences:

>Translated_445_residues
MHPVLIFLFALIAILLFTAKFRLHPFLSLVLVSLLTGILAGEPIRTIEAVTEGLGSVFSRFAIIITSGSIIGLLLQKTGG
MSLIASDITRFFKNPLLALSFLGFLFSVPTMCYILAYVIFIPIAKELSSRFNYPPISTATALALGAVASFNLVYPSPVII
SAAEELSANRDMLILLGFLTAVPTSFSGYLYARSLGKAEVSGMNEGGVIREKTIVKEKKDLSQENGALQRTENRKPGRFE
AYAPIFIPLFLILFEAVLNNPNTLFTFLGNPNVALLIGVLLSIFSGRVLGLPMIRVQVEKAIKRSGVVLLDLCGGGALGA
TLAMTGAGEALGKFFLQFNLPHILVPFLVAAALQTVQGSRVVTMLVAPSLLLPLVPELGLPPEILILSMASGTFMISHVN
DPFFWIFGELAELTPSEVFRSNTLGNALMGVVSFLIVSGIYFFFY
>Mature_445_residues
MHPVLIFLFALIAILLFTAKFRLHPFLSLVLVSLLTGILAGEPIRTIEAVTEGLGSVFSRFAIIITSGSIIGLLLQKTGG
MSLIASDITRFFKNPLLALSFLGFLFSVPTMCYILAYVIFIPIAKELSSRFNYPPISTATALALGAVASFNLVYPSPVII
SAAEELSANRDMLILLGFLTAVPTSFSGYLYARSLGKAEVSGMNEGGVIREKTIVKEKKDLSQENGALQRTENRKPGRFE
AYAPIFIPLFLILFEAVLNNPNTLFTFLGNPNVALLIGVLLSIFSGRVLGLPMIRVQVEKAIKRSGVVLLDLCGGGALGA
TLAMTGAGEALGKFFLQFNLPHILVPFLVAAALQTVQGSRVVTMLVAPSLLLPLVPELGLPPEILILSMASGTFMISHVN
DPFFWIFGELAELTPSEVFRSNTLGNALMGVVSFLIVSGIYFFFY

Specific function: Part Of The Gluconate Utilization System Gnt-I; Low- Affinity Intake Of Gluconate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=432, Percent_Identity=26.3888888888889, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI48994939, Length=457, Percent_Identity=25.382932166302, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1790716, Length=445, Percent_Identity=25.6179775280899, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788707, Length=446, Percent_Identity=25.5605381165919, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1789097, Length=455, Percent_Identity=26.8131868131868, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1790776, Length=464, Percent_Identity=22.8448275862069, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI2367370, Length=431, Percent_Identity=23.6658932714617, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 48004; Mature: 48004

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPVLIFLFALIAILLFTAKFRLHPFLSLVLVSLLTGILAGEPIRTIEAVTEGLGSVFSR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FAIIITSGSIIGLLLQKTGGMSLIASDITRFFKNPLLALSFLGFLFSVPTMCYILAYVIF
HHHEEECCHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
IPIAKELSSRFNYPPISTATALALGAVASFNLVYPSPVIISAAEELSANRDMLILLGFLT
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCEECCCCCEEECHHHHCCCCCHHHHHHHHH
AVPTSFSGYLYARSLGKAEVSGMNEGGVIREKTIVKEKKDLSQENGALQRTENRKPGRFE
HCCCCCCCHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
AYAPIFIPLFLILFEAVLNNPNTLFTFLGNPNVALLIGVLLSIFSGRVLGLPMIRVQVEK
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AIKRSGVVLLDLCGGGALGATLAMTGAGEALGKFFLQFNLPHILVPFLVAAALQTVQGSR
HHHHCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCH
VVTMLVAPSLLLPLVPELGLPPEILILSMASGTFMISHVNDPFFWIFGELAELTPSEVFR
HHHHHHHHHHHHHHCCCCCCCHHHEEEEECCCEEEEEECCCCHHHHHHHHHHCCHHHHHH
SNTLGNALMGVVSFLIVSGIYFFFY
HCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHPVLIFLFALIAILLFTAKFRLHPFLSLVLVSLLTGILAGEPIRTIEAVTEGLGSVFSR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FAIIITSGSIIGLLLQKTGGMSLIASDITRFFKNPLLALSFLGFLFSVPTMCYILAYVIF
HHHEEECCHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
IPIAKELSSRFNYPPISTATALALGAVASFNLVYPSPVIISAAEELSANRDMLILLGFLT
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCEECCCCCEEECHHHHCCCCCHHHHHHHHH
AVPTSFSGYLYARSLGKAEVSGMNEGGVIREKTIVKEKKDLSQENGALQRTENRKPGRFE
HCCCCCCCHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
AYAPIFIPLFLILFEAVLNNPNTLFTFLGNPNVALLIGVLLSIFSGRVLGLPMIRVQVEK
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AIKRSGVVLLDLCGGGALGATLAMTGAGEALGKFFLQFNLPHILVPFLVAAALQTVQGSR
HHHHCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCH
VVTMLVAPSLLLPLVPELGLPPEILILSMASGTFMISHVNDPFFWIFGELAELTPSEVFR
HHHHHHHHHHHHHHCCCCCCCHHHEEEEECCCEEEEEECCCCHHHHHHHHHHCCHHHHHH
SNTLGNALMGVVSFLIVSGIYFFFY
HCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA