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The map label for this gene is tpiA [H]

Identifier: 21227380

GI number: 21227380

Start: 1513886

End: 1514554

Strand: Reverse

Name: tpiA [H]

Synonym: MM_1278

Alternate gene names: 21227380

Gene position: 1514554-1513886 (Counterclockwise)

Preceding gene: 21227381

Following gene: 21227379

Centisome position: 36.97

GC content: 47.09

Gene sequence:

>669_bases
TTGGGTTCACCATTCATTTTACTGAACTATAAGACTTATATACAGGGCACAGGCAAGGGCGCAGTTGATATTGCAAAAGC
CTGCAAAACCGTATCCGAAGAGTCAGGTATCGAGATTGCAGTAGCTCCTCAGCTTCCGGATATTTACAGGGTAGCTTCCG
AAGTTGAACTTTCGGTTTTTTCCCAGCACATGGACGGCATAGGAGCAGGAAGTTTTACAGGTCATGTTTTCGGAAAATGT
ATAAAAGAAGCAGGAGCTTTCGGGACTCTTATCAACCACTCTGAAAGGCGTCTGACCCTTGCGGAAATCGAAGCTTCGTT
GAAAGCTGCAAAAGAGTTCGGGCTCAGGGCAATTATATGCACCAACAACGTCCCCACAACTGCAGCAGCTGCAGCGCTTG
TTCCTGATTACGTAGCAATCGAGCCACCTGAGCTTATAGGTAGCGGAATTCCTGTCTCAAAAGCCGACCCTGAAGTTGTC
AGTGGTTCTGTTGAAGCGGTTTCAAAGATCAATCCTGATGTAAAAGTGCTTTGTGGAGCCGGAATTTCAAAAGGTGAAGA
CCTGAGGGCAGCCCTTGACCTTGGCTCGCAGGGAGTACTACTCGCATCCGGTATAGTGAAAGCTTCAGATCCTAAAGCTG
CACTTGAAGACCTTATTCGGCTTGTTTAA

Upstream 100 bases:

>100_bases
GCCTTAATAAGCCAGAGATTGACCAGTTCAGAGTCATGACAGACTTCTGAAAGCGTGTATTTTCACGCTTTTTCTTTTCT
TTTTTCAGGAGGGGATTTTT

Downstream 100 bases:

>100_bases
GTCTTTACTTTGTTGAATTTCAGGTTGAGCTTTAGATTCGTCTTTATTTGATGAGAGTTCTGTTATTTTCTCATCTTTTT
TTCTGTTTTCTTATCTCCAG

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MGSPFILLNYKTYIQGTGKGAVDIAKACKTVSEESGIEIAVAPQLPDIYRVASEVELSVFSQHMDGIGAGSFTGHVFGKC
IKEAGAFGTLINHSERRLTLAEIEASLKAAKEFGLRAIICTNNVPTTAAAAALVPDYVAIEPPELIGSGIPVSKADPEVV
SGSVEAVSKINPDVKVLCGAGISKGEDLRAALDLGSQGVLLASGIVKASDPKAALEDLIRLV

Sequences:

>Translated_222_residues
MGSPFILLNYKTYIQGTGKGAVDIAKACKTVSEESGIEIAVAPQLPDIYRVASEVELSVFSQHMDGIGAGSFTGHVFGKC
IKEAGAFGTLINHSERRLTLAEIEASLKAAKEFGLRAIICTNNVPTTAAAAALVPDYVAIEPPELIGSGIPVSKADPEVV
SGSVEAVSKINPDVKVLCGAGISKGEDLRAALDLGSQGVLLASGIVKASDPKAALEDLIRLV
>Mature_221_residues
GSPFILLNYKTYIQGTGKGAVDIAKACKTVSEESGIEIAVAPQLPDIYRVASEVELSVFSQHMDGIGAGSFTGHVFGKCI
KEAGAFGTLINHSERRLTLAEIEASLKAAKEFGLRAIICTNNVPTTAAAAALVPDYVAIEPPELIGSGIPVSKADPEVVS
GSVEAVSKINPDVKVLCGAGISKGEDLRAALDLGSQGVLLASGIVKASDPKAALEDLIRLV

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

None

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000652
- InterPro:   IPR022891 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 22930; Mature: 22798

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSPFILLNYKTYIQGTGKGAVDIAKACKTVSEESGIEIAVAPQLPDIYRVASEVELSVF
CCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHH
SQHMDGIGAGSFTGHVFGKCIKEAGAFGTLINHSERRLTLAEIEASLKAAKEFGLRAIIC
HHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCEEHHHHHHHHHHHHHHHCCEEEEE
TNNVPTTAAAAALVPDYVAIEPPELIGSGIPVSKADPEVVSGSVEAVSKINPDVKVLCGA
ECCCCCHHHHHHHCCCCCEECCHHHHCCCCCCCCCCHHHHCCHHHHHHHCCCCEEEEECC
GISKGEDLRAALDLGSQGVLLASGIVKASDPKAALEDLIRLV
CCCCCCHHHHHHCCCCCCEEEECCCEECCCHHHHHHHHHHHC
>Mature Secondary Structure 
GSPFILLNYKTYIQGTGKGAVDIAKACKTVSEESGIEIAVAPQLPDIYRVASEVELSVF
CCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHH
SQHMDGIGAGSFTGHVFGKCIKEAGAFGTLINHSERRLTLAEIEASLKAAKEFGLRAIIC
HHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCEEHHHHHHHHHHHHHHHCCEEEEE
TNNVPTTAAAAALVPDYVAIEPPELIGSGIPVSKADPEVVSGSVEAVSKINPDVKVLCGA
ECCCCCHHHHHHHCCCCCEECCHHHHCCCCCCCCCCHHHHCCHHHHHHHCCCCEEEEECC
GISKGEDLRAALDLGSQGVLLASGIVKASDPKAALEDLIRLV
CCCCCCHHHHHHCCCCCCEEEECCCEECCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]