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The map label for this gene is 21227160

Identifier: 21227160

GI number: 21227160

Start: 1240733

End: 1241404

Strand: Direct

Name: 21227160

Synonym: MM_1058

Alternate gene names: NA

Gene position: 1240733-1241404 (Clockwise)

Preceding gene: 21227157

Following gene: 21227161

Centisome position: 30.29

GC content: 43.45

Gene sequence:

>672_bases
ATGCTACCCAGACTGGTTATACACAACAGCATAAGCCCTGACGGCTCAACCACTGGTTTTGATGCAAACCTTGATGTTCA
CTATGGGATCCTGGGCAGTTACGAACCCGATGCCATGATAGTAGGGTCGAATACCGCAAAGGTGGGGACACAATTTTTTT
GCGAAAAGATACCTCCTGAAGATAAAGAAGACTTCAAAAAGCCTGATATCCATCCGGATGATACAAGGGCTTACTGGATG
ATCGCAGACTCAAGAGGGACTCTCGAAGGGCTTATGCACGTATTCAGGCGTTCAGAATATAGTAAAGACATAATCGTACT
CGTCTCGGAGAAAACCCCTGAATCTTACATAAATTACCTCAAGGAAAGAGATTATGATTTTATCCGGGCAGGGGTGGAAC
GTGTGGATGTCAGGCAGGGTCTTGAAATTGCAGGTGAAAGATACGGATTTAAACTTGTGGTTTCAGACAGCGGAGGAATA
TTAAACAGTATTTTACTTGAACAGGGACTCGTTGATGAAATAAGTTTGGTCCTGACTCCGGAAATTGTTGGGAAAAGCGG
GACGAACCTTTTCAGGGGAATTGAGAAAAGCGGGATTCAACTGGAGCTTTCAAGAAACGAGATTGTGGAAAAGAAATATG
TGCACCTTGTTTACAGGGTTTTGAAAGAATAA

Upstream 100 bases:

>100_bases
TATATTCCAAGATAGAATAAGTTTATTGAATGTTTGATTTAAGTTAATACAACTTTAATTAAACTATATATGCTTTTAAT
TTGGGGGAAGAGGTGAAAAC

Downstream 100 bases:

>100_bases
GGATAAGAGCAAAGATAAGGCAGAAAATTATCTCAAGTACGAAAAAACCTGTAGATATAGTTGCAAGTTCGCCAGGGGGA
CTTAAAAAGAGCCCATACCG

Product: 5-amino-6-(5-phosphoribosylamino)uracil reductase

Products: 5-amino-6-(5-phosphoribosylamino)uracil; NADPH; H+

Alternate protein names: Deaminase-Reductase Domain-Containing Protein; Bifunctional Deaminase-Reductase Domain Protein; 5-Amino-6-(5-Phosphoribosylamino)Uracil Reductase; Bifunctional Deaminase-Reductase Domain-Containing Protein; 5-Amino-6-(5-Phosphoribosylamino)Uracilreductase

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MLPRLVIHNSISPDGSTTGFDANLDVHYGILGSYEPDAMIVGSNTAKVGTQFFCEKIPPEDKEDFKKPDIHPDDTRAYWM
IADSRGTLEGLMHVFRRSEYSKDIIVLVSEKTPESYINYLKERDYDFIRAGVERVDVRQGLEIAGERYGFKLVVSDSGGI
LNSILLEQGLVDEISLVLTPEIVGKSGTNLFRGIEKSGIQLELSRNEIVEKKYVHLVYRVLKE

Sequences:

>Translated_223_residues
MLPRLVIHNSISPDGSTTGFDANLDVHYGILGSYEPDAMIVGSNTAKVGTQFFCEKIPPEDKEDFKKPDIHPDDTRAYWM
IADSRGTLEGLMHVFRRSEYSKDIIVLVSEKTPESYINYLKERDYDFIRAGVERVDVRQGLEIAGERYGFKLVVSDSGGI
LNSILLEQGLVDEISLVLTPEIVGKSGTNLFRGIEKSGIQLELSRNEIVEKKYVHLVYRVLKE
>Mature_223_residues
MLPRLVIHNSISPDGSTTGFDANLDVHYGILGSYEPDAMIVGSNTAKVGTQFFCEKIPPEDKEDFKKPDIHPDDTRAYWM
IADSRGTLEGLMHVFRRSEYSKDIIVLVSEKTPESYINYLKERDYDFIRAGVERVDVRQGLEIAGERYGFKLVVSDSGGI
LNSILLEQGLVDEISLVLTPEIVGKSGTNLFRGIEKSGIQLELSRNEIVEKKYVHLVYRVLKE

Specific function: Unknown

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.193

Molecular weight: Translated: 25143; Mature: 25143

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPRLVIHNSISPDGSTTGFDANLDVHYGILGSYEPDAMIVGSNTAKVGTQFFCEKIPPE
CCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCHHHHHHHHHHCCCCC
DKEDFKKPDIHPDDTRAYWMIADSRGTLEGLMHVFRRSEYSKDIIVLVSEKTPESYINYL
CHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHH
KERDYDFIRAGVERVDVRQGLEIAGERYGFKLVVSDSGGILNSILLEQGLVDEISLVLTP
HHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHEEECH
EIVGKSGTNLFRGIEKSGIQLELSRNEIVEKKYVHLVYRVLKE
HHHCCCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLPRLVIHNSISPDGSTTGFDANLDVHYGILGSYEPDAMIVGSNTAKVGTQFFCEKIPPE
CCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCHHHHHHHHHHCCCCC
DKEDFKKPDIHPDDTRAYWMIADSRGTLEGLMHVFRRSEYSKDIIVLVSEKTPESYINYL
CHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHH
KERDYDFIRAGVERVDVRQGLEIAGERYGFKLVVSDSGGILNSILLEQGLVDEISLVLTP
HHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHEEECH
EIVGKSGTNLFRGIEKSGIQLELSRNEIVEKKYVHLVYRVLKE
HHHCCCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-amino-6-(5-phosphoribitylamino)uracil; NADP+

Specific reaction: 5-amino-6-(5-phosphoribitylamino)uracil + NADP+ = 5-amino-6-(5-phosphoribosylamino)uracil + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA