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The map label for this gene is sppA [H]

Identifier: 21226968

GI number: 21226968

Start: 1023258

End: 1024490

Strand: Reverse

Name: sppA [H]

Synonym: MM_0866

Alternate gene names: 21226968

Gene position: 1024490-1023258 (Counterclockwise)

Preceding gene: 21226970

Following gene: 21226967

Centisome position: 25.01

GC content: 44.85

Gene sequence:

>1233_bases
ATGAATGATGAAAATGTAAATTCAGATGGTGTGGATTCAAAAAACACGAGTCCTGAAGAGATGTCTGGAGACAGCCTGTC
GGAAAATGATGTTTATAATAAAAAAGAAATTACTGCTCACGATGGGGACATTTCGGAGAGTAAAATAAAAGAAAATTCCT
CTGGTTCCTATTCCGTTTCTGAAAAGCAGCAGGAGGCGGCAAAATCAGATGTTCAGGAACCTTCTCAGCCGGAACCTCAT
AATACTATTAAAAGTGAGCGTTTAAACATGAATTCAGGCTCTTCTCCTTCCCTGCCGAAAAAGAAACGCAGTGGGGCTTC
TTATCTTATCGTATTGCTGGCTTTAATTGCTGTCATTGCGGTTAGTATAGCCGCTATTTTTTACGGGCTTGGTTTCGGAG
GAAATATCGGGAGTTCCGATAAGATAGCGGTCATTTATGTGCAGGGTACCATGCTCACCGGAAATGTTCCTGCAGGGCTC
GGCTATGCAACCTCGGAAGAAATTTGTCAAAACATTCACTCTGCTGTAGAGGATAATAACGTCAGGGCGATCGTACTCCG
GGTAAACAGCGGTGGAGGCTCTCCTTCAGCCGCTCAGGAAATAGCAATAGAGATAGAGAAAGCTCAGAAACAGGGAGTCC
CGGTCATTGTTTCCATGGGGGATCTTGCAGCCAGCGCGGCGTACTACATCTCTGCCCCGGCAGATTACATATTTGCAAAT
CCTTCCACAAATACGGGGTCTATTGGAGTCATCTGGACCTTTGAAAATATGTCTGGCTTTTACCAGAATGAAGGCATAAA
TTATTATGTTTCGAAGTCCGGAGAGTTTAAAGATATGGGAGGGACCTGGAGAGGGTTGACCGACGAAGAAAAAGAATATG
CTGATGAAGTTGTAATGGAGAGTTATGAAGAGTTTGTAACCCAGGTTGCCGAAGGGCGGAATATAAGCCGGAGTGAAGTA
AAAAAACTTGCTGACGGGCGCATTTATACCGGATCAAGAGCAAAAGATCTCGGGCTTGTAGATGACTTTGGAAACCTCTA
TGATGCAATTGATAAGGCTGCGGAACTCGGAGGTGTCCAGGGTAAGCCAAAAGTTGTTTATATGAACAGGGCGACCCTCT
CAAGCTTGCTTCTGGGCTCGGAAACGGACAACTCAAGCGAGGGAGCAGGTCAATTCGTCAGTTATTTTGAGGAAAGTCCT
TATGGGAAAGTCCTTGCATGTTTGCGCAATTAA

Upstream 100 bases:

>100_bases
ACTGGAAATTTGCCTGCCCCTTAACTGGAGTTTTCAGCAGTGAAAAAGTACAGACCGGGGAAGTTAGAGAAACAAATCCA
AAAAATACGGTCATGTCAAT

Downstream 100 bases:

>100_bases
CGGATTTTCTGACTTTCCTTCTCCATTACTTATTTTTCGGGTTTTAATTTCTTGTGCAGGCTTGCAGCCTGAAAATAGTA
AAATATATATTAGCTAACAT

Product: periplasmic serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MNDENVNSDGVDSKNTSPEEMSGDSLSENDVYNKKEITAHDGDISESKIKENSSGSYSVSEKQQEAAKSDVQEPSQPEPH
NTIKSERLNMNSGSSPSLPKKKRSGASYLIVLLALIAVIAVSIAAIFYGLGFGGNIGSSDKIAVIYVQGTMLTGNVPAGL
GYATSEEICQNIHSAVEDNNVRAIVLRVNSGGGSPSAAQEIAIEIEKAQKQGVPVIVSMGDLAASAAYYISAPADYIFAN
PSTNTGSIGVIWTFENMSGFYQNEGINYYVSKSGEFKDMGGTWRGLTDEEKEYADEVVMESYEEFVTQVAEGRNISRSEV
KKLADGRIYTGSRAKDLGLVDDFGNLYDAIDKAAELGGVQGKPKVVYMNRATLSSLLLGSETDNSSEGAGQFVSYFEESP
YGKVLACLRN

Sequences:

>Translated_410_residues
MNDENVNSDGVDSKNTSPEEMSGDSLSENDVYNKKEITAHDGDISESKIKENSSGSYSVSEKQQEAAKSDVQEPSQPEPH
NTIKSERLNMNSGSSPSLPKKKRSGASYLIVLLALIAVIAVSIAAIFYGLGFGGNIGSSDKIAVIYVQGTMLTGNVPAGL
GYATSEEICQNIHSAVEDNNVRAIVLRVNSGGGSPSAAQEIAIEIEKAQKQGVPVIVSMGDLAASAAYYISAPADYIFAN
PSTNTGSIGVIWTFENMSGFYQNEGINYYVSKSGEFKDMGGTWRGLTDEEKEYADEVVMESYEEFVTQVAEGRNISRSEV
KKLADGRIYTGSRAKDLGLVDDFGNLYDAIDKAAELGGVQGKPKVVYMNRATLSSLLLGSETDNSSEGAGQFVSYFEESP
YGKVLACLRN
>Mature_410_residues
MNDENVNSDGVDSKNTSPEEMSGDSLSENDVYNKKEITAHDGDISESKIKENSSGSYSVSEKQQEAAKSDVQEPSQPEPH
NTIKSERLNMNSGSSPSLPKKKRSGASYLIVLLALIAVIAVSIAAIFYGLGFGGNIGSSDKIAVIYVQGTMLTGNVPAGL
GYATSEEICQNIHSAVEDNNVRAIVLRVNSGGGSPSAAQEIAIEIEKAQKQGVPVIVSMGDLAASAAYYISAPADYIFAN
PSTNTGSIGVIWTFENMSGFYQNEGINYYVSKSGEFKDMGGTWRGLTDEEKEYADEVVMESYEEFVTQVAEGRNISRSEV
KKLADGRIYTGSRAKDLGLVDDFGNLYDAIDKAAELGGVQGKPKVVYMNRATLSSLLLGSETDNSSEGAGQFVSYFEESP
YGKVLACLRN

Specific function: Digestion of the cleaved signal peptides [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=236, Percent_Identity=36.4406779661017, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1787527, Length=204, Percent_Identity=25.9803921568627, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 43899; Mature: 43899

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDENVNSDGVDSKNTSPEEMSGDSLSENDVYNKKEITAHDGDISESKIKENSSGSYSVS
CCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCHHHHCCCCCCCCCCH
EKQQEAAKSDVQEPSQPEPHNTIKSERLNMNSGSSPSLPKKKRSGASYLIVLLALIAVIA
HHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHH
VSIAAIFYGLGFGGNIGSSDKIAVIYVQGTMLTGNVPAGLGYATSEEICQNIHSAVEDNN
HHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCC
VRAIVLRVNSGGGSPSAAQEIAIEIEKAQKQGVPVIVSMGDLAASAAYYISAPADYIFAN
EEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHCCEEEEECCCCEEEEC
PSTNTGSIGVIWTFENMSGFYQNEGINYYVSKSGEFKDMGGTWRGLTDEEKEYADEVVME
CCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
SYEEFVTQVAEGRNISRSEVKKLADGRIYTGSRAKDLGLVDDFGNLYDAIDKAAELGGVQ
HHHHHHHHHHCCCCCCHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
GKPKVVYMNRATLSSLLLGSETDNSSEGAGQFVSYFEESPYGKVLACLRN
CCCEEEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MNDENVNSDGVDSKNTSPEEMSGDSLSENDVYNKKEITAHDGDISESKIKENSSGSYSVS
CCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCHHHHCCCCCCCCCCH
EKQQEAAKSDVQEPSQPEPHNTIKSERLNMNSGSSPSLPKKKRSGASYLIVLLALIAVIA
HHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHH
VSIAAIFYGLGFGGNIGSSDKIAVIYVQGTMLTGNVPAGLGYATSEEICQNIHSAVEDNN
HHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCC
VRAIVLRVNSGGGSPSAAQEIAIEIEKAQKQGVPVIVSMGDLAASAAYYISAPADYIFAN
EEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHCCEEEEECCCCEEEEC
PSTNTGSIGVIWTFENMSGFYQNEGINYYVSKSGEFKDMGGTWRGLTDEEKEYADEVVME
CCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
SYEEFVTQVAEGRNISRSEVKKLADGRIYTGSRAKDLGLVDDFGNLYDAIDKAAELGGVQ
HHHHHHHHHHCCCCCCHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
GKPKVVYMNRATLSSLLLGSETDNSSEGAGQFVSYFEESPYGKVLACLRN
CCCEEEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]