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The map label for this gene is 21226970

Identifier: 21226970

GI number: 21226970

Start: 1027183

End: 1027713

Strand: Reverse

Name: 21226970

Synonym: MM_0868

Alternate gene names: NA

Gene position: 1027713-1027183 (Counterclockwise)

Preceding gene: 21226971

Following gene: 21226968

Centisome position: 25.09

GC content: 44.63

Gene sequence:

>531_bases
ATGATTGAAGTGGAAGTCAAGGTTAGAGCGGATCACTCAAAGATCCGCCCTGTCCTTATGGAAATGGGGGCGAGTAAAAT
CGGGGTTGAAGAACAGTCAGATGTCTATTTTGCAGCTCCCTACCGCGATTTTGCAAAGACCGATGAGGCTCTCAGGATAC
GCTCTCTGGGAGGACATTCTGTGCTGACCTATAAAGGTCCTAAACTTGATAAAGTTTCCAAAACCAGAGTGGAGATCGAA
ACTCCAGTAGATGGGACTGCTACAGCTAAAATTTTCCACTCCCTGGGCTTCCTGGAAGCCGGTGCAGTCCGCAAAAAAAG
GGATATTTTCAGAGCAGGAGAGATTATTGTCTGTCTTGATGCCGTCGAAGGGCTCGGAGAGTTTCTGGAAGTAGAGCTCG
ATGTGGAAGATAAAAAAGATCTCGAAAGTTCAAGGGCAGAATTATTTAAATTCTTATCTCAGTTTGGCCTGAGTGAAAAA
GATTCTATCCGGACTTCTTACCTTGAAATGGTGCTGGAAAAAAGAAATTGA

Upstream 100 bases:

>100_bases
TTTCCTTCCAGGCATCTGCTGTTAATTCCCCTATTAATTAATAATGGATTAAACCATAAATTGAGCCAAACCATAAATTG
AGCCGGAGATGTCTGGAATT

Downstream 100 bases:

>100_bases
TAACGTTCCTGGATTATAACTTTTCTGGATTATAATTTTCCTGGGTTTTAATTTTCCTGGGTTTTAATTTTCCTGGATTA
GCTGTTATCTTCATGCCCGC

Product: adenylate cyclase

Products: 3',5'-cyclic AMP; diphosphate

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MIEVEVKVRADHSKIRPVLMEMGASKIGVEEQSDVYFAAPYRDFAKTDEALRIRSLGGHSVLTYKGPKLDKVSKTRVEIE
TPVDGTATAKIFHSLGFLEAGAVRKKRDIFRAGEIIVCLDAVEGLGEFLEVELDVEDKKDLESSRAELFKFLSQFGLSEK
DSIRTSYLEMVLEKRN

Sequences:

>Translated_176_residues
MIEVEVKVRADHSKIRPVLMEMGASKIGVEEQSDVYFAAPYRDFAKTDEALRIRSLGGHSVLTYKGPKLDKVSKTRVEIE
TPVDGTATAKIFHSLGFLEAGAVRKKRDIFRAGEIIVCLDAVEGLGEFLEVELDVEDKKDLESSRAELFKFLSQFGLSEK
DSIRTSYLEMVLEKRN
>Mature_176_residues
MIEVEVKVRADHSKIRPVLMEMGASKIGVEEQSDVYFAAPYRDFAKTDEALRIRSLGGHSVLTYKGPKLDKVSKTRVEIE
TPVDGTATAKIFHSLGFLEAGAVRKKRDIFRAGEIIVCLDAVEGLGEFLEVELDVEDKKDLESSRAELFKFLSQFGLSEK
DSIRTSYLEMVLEKRN

Specific function: Unknown

COG id: COG1437

COG function: function code F; Adenylate cyclase, class 2 (thermophilic)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008172
- InterPro:   IPR008173
- InterPro:   IPR004206 [H]

Pfam domain/function: PF01928 CYTH [H]

EC number: 4.6.1.1

Molecular weight: Translated: 19772; Mature: 19772

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEVEVKVRADHSKIRPVLMEMGASKIGVEEQSDVYFAAPYRDFAKTDEALRIRSLGGHS
CEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHCCCHHEEEEECCCCE
VLTYKGPKLDKVSKTRVEIETPVDGTATAKIFHSLGFLEAGAVRKKRDIFRAGEIIVCLD
EEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCHHHCHHHHHHHHHHCCCEEEEEH
AVEGLGEFLEVELDVEDKKDLESSRAELFKFLSQFGLSEKDSIRTSYLEMVLEKRN
HHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIEVEVKVRADHSKIRPVLMEMGASKIGVEEQSDVYFAAPYRDFAKTDEALRIRSLGGHS
CEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHCCCHHEEEEECCCCE
VLTYKGPKLDKVSKTRVEIETPVDGTATAKIFHSLGFLEAGAVRKKRDIFRAGEIIVCLD
EEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCHHHCHHHHHHHHHHCCCEEEEEH
AVEGLGEFLEVELDVEDKKDLESSRAELFKFLSQFGLSEKDSIRTSYLEMVLEKRN
HHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP

Specific reaction: ATP = 3',5'-cyclic AMP + diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]