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The map label for this gene is panE [C]

Identifier: 212224616

GI number: 212224616

Start: 1342624

End: 1343523

Strand: Reverse

Name: panE [C]

Synonym: TON_1465

Alternate gene names: 212224616

Gene position: 1343523-1342624 (Counterclockwise)

Preceding gene: 212224622

Following gene: 212224615

Centisome position: 72.72

GC content: 52.22

Gene sequence:

>900_bases
ATGAAGATTTACATCCTCGGTGCGGGTTCAATAGGTTCACTTTTCGGTGCCCTTCTGACGAGGGCTGGAAACGATGTAAC
GCTCATCGGCAGGGAGGATCAGGTGAGGGCGATAAATGAGAACGGTCTTCACGTCCTTGGCGTTGAGGAGTTCACAGTTT
ATCCCAATGCAAGCCTCTATGCTCCTGAAGAGCCCCCCGATCTTCTCATACTGGCCACAAAGTCGTATTCAACTAAAACT
GCCCTGGAGTGCGCAAGGAACTGCATCGGCCCGGAAACTTGGGTGCTGAGTATACAGAACGGCCTCGGGAACGAGGAGTT
AGCTTTGAAGATAACTCCAAACGTCATGGGGGGAATAACAACCAATGGGGCCATGCTGGTTGGGTGGGGCAGAGTGAAGT
GGACCGGCAGGGGAATAACGGTCGTAGGAAAGTATCCTACCGGAACCCATCCCTTCGTGGAAGAGGTCGCGGAGACTTTT
AACGGGGCCGGAATAGAAACGCACACAACCGAGAACGTTATCGGCTGGAAGTGGGCGAAGGCCATAGTCAACTCCGTCAT
CAATGGACTTGGAACTGTTCTCGAAGTGAAAAACGGCTTTCTGAAGGATGATCCCTACCTCGAGGGCATCTCTGTGGATA
TAGCGCGCGAAGGATGCACGGTGGCGCGGCAGCTGGGGATAGAGTTTGAGATCCACCCACTGGAGCTTCTCTGGGACACA
ATAGAGAAAACCCGTGAGAACTACAACTCAACCCTTCAAGACATAAAGAGAAGAAAGAGGACAGAGGTTGACTACATTCA
CGGAAAGATAGTGGAGTACGCGAGGAGTGTGGGGCTTGAAGCTCCAAGGAACGAGCTTCTCTGGGCGCTCATTAAGGCCA
AGGAGGAGCAAAGTAGATAA

Upstream 100 bases:

>100_bases
TCATGCCTATGTTTGCAGGCCCCTCAGGTTCGACCAGAATCACATTGAGCTTCATCGGTAAGGCTTTAAGGGGGAGGCTT
TAAATGATTGCGGTGGTGAG

Downstream 100 bases:

>100_bases
ACCCACCAATCGAGGTTATTGTGGGGGATGAAAAATGCCCATATTTGGCGGAAAAGAAAGTGGGGTTTTTGATACTATTG
AAAAGCACCTTGAGGTTGTC

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MKIYILGAGSIGSLFGALLTRAGNDVTLIGREDQVRAINENGLHVLGVEEFTVYPNASLYAPEEPPDLLILATKSYSTKT
ALECARNCIGPETWVLSIQNGLGNEELALKITPNVMGGITTNGAMLVGWGRVKWTGRGITVVGKYPTGTHPFVEEVAETF
NGAGIETHTTENVIGWKWAKAIVNSVINGLGTVLEVKNGFLKDDPYLEGISVDIAREGCTVARQLGIEFEIHPLELLWDT
IEKTRENYNSTLQDIKRRKRTEVDYIHGKIVEYARSVGLEAPRNELLWALIKAKEEQSR

Sequences:

>Translated_299_residues
MKIYILGAGSIGSLFGALLTRAGNDVTLIGREDQVRAINENGLHVLGVEEFTVYPNASLYAPEEPPDLLILATKSYSTKT
ALECARNCIGPETWVLSIQNGLGNEELALKITPNVMGGITTNGAMLVGWGRVKWTGRGITVVGKYPTGTHPFVEEVAETF
NGAGIETHTTENVIGWKWAKAIVNSVINGLGTVLEVKNGFLKDDPYLEGISVDIAREGCTVARQLGIEFEIHPLELLWDT
IEKTRENYNSTLQDIKRRKRTEVDYIHGKIVEYARSVGLEAPRNELLWALIKAKEEQSR
>Mature_299_residues
MKIYILGAGSIGSLFGALLTRAGNDVTLIGREDQVRAINENGLHVLGVEEFTVYPNASLYAPEEPPDLLILATKSYSTKT
ALECARNCIGPETWVLSIQNGLGNEELALKITPNVMGGITTNGAMLVGWGRVKWTGRGITVVGKYPTGTHPFVEEVAETF
NGAGIETHTTENVIGWKWAKAIVNSVINGLGTVLEVKNGFLKDDPYLEGISVDIAREGCTVARQLGIEFEIHPLELLWDT
IEKTRENYNSTLQDIKRRKRTEVDYIHGKIVEYARSVGLEAPRNELLWALIKAKEEQSR

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=309, Percent_Identity=29.126213592233, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 32921; Mature: 32921

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYILGAGSIGSLFGALLTRAGNDVTLIGREDQVRAINENGLHVLGVEEFTVYPNASLY
CEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCEEEEEEEEEEECCCCEEE
APEEPPDLLILATKSYSTKTALECARNCIGPETWVLSIQNGLGNEELALKITPNVMGGIT
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCCHHCCEE
TNGAMLVGWGRVKWTGRGITVVGKYPTGTHPFVEEVAETFNGAGIETHTTENVIGWKWAK
CCCEEEEEECEEEEECCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
AIVNSVINGLGTVLEVKNGFLKDDPYLEGISVDIAREGCTVARQLGIEFEIHPLELLWDT
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHCCCEEEECHHHHHHHH
IEKTRENYNSTLQDIKRRKRTEVDYIHGKIVEYARSVGLEAPRNELLWALIKAKEEQSR
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIYILGAGSIGSLFGALLTRAGNDVTLIGREDQVRAINENGLHVLGVEEFTVYPNASLY
CEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCEEEEEEEEEEECCCCEEE
APEEPPDLLILATKSYSTKTALECARNCIGPETWVLSIQNGLGNEELALKITPNVMGGIT
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCCHHCCEE
TNGAMLVGWGRVKWTGRGITVVGKYPTGTHPFVEEVAETFNGAGIETHTTENVIGWKWAK
CCCEEEEEECEEEEECCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
AIVNSVINGLGTVLEVKNGFLKDDPYLEGISVDIAREGCTVARQLGIEFEIHPLELLWDT
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHCCCEEEECHHHHHHHH
IEKTRENYNSTLQDIKRRKRTEVDYIHGKIVEYARSVGLEAPRNELLWALIKAKEEQSR
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]