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The map label for this gene is hslO

Identifier: 209696325

GI number: 209696325

Start: 3170167

End: 3171042

Strand: Direct

Name: hslO

Synonym: VSAL_I2927

Alternate gene names: 209696325

Gene position: 3170167-3171042 (Clockwise)

Preceding gene: 209696324

Following gene: 209696326

Centisome position: 95.34

GC content: 40.98

Gene sequence:

>876_bases
ATGGCAAATAACACATTGCATCGTTACCTGTTTGAAGATTTATCCGTTCGTGGTGAATTAGTTCAATTAGATGATGCTTA
CCAACAAATTATTTCTAGCAAGGAATACCCAAAGCCAGTACAAAACTTATTGGGTGAGCTATTAGTTGCAACCACATTAT
TAACCGCCACGTTGAAATTTGAAGGATCGATTACGCTTCAACTTCAAGGTAATGGTCCTGTCTCTCTTGTGGTTATTAAC
GGCGATAACGATCAAAAAGTTCGTGGCGTTGCTCGCTTTGAAGGCGAAATTGCTGACGACGCGACATTACATCAACTAAT
GGGTAAAGGTTATTTAGTTATTACTATCTCGCCTAAAGACGGCGAACGTTACCAAGGTGTTGTTGCTCTTGAAGGGAAAG
ATTTAGCCGAATGTTTTGAAGGATACTTTGAGCGTTCTGAGCAATTAAAAACTCGTTTATGGTTACGTCTTGGTGAATTT
GAAGGCAAACCACACGCTGCGGGTATGCTGCTTCAAGTCATGCCTGATGGGACTGGCTCTTCGGATGATTTTGAGCATTT
AGAGCAACTAACGGATACCGTTAAAAACGAAGAACTCTTCAGCTTAGAAGCGGAAGATGTACTTTACCGTTTGTATAACC
AAGATAAAGTTCAGTTGTTTGAACCTCAAAACGTTGAATTTTTCTGTGGGTGTTCTCGTGAACGCAGTGGCGGCGCCATC
ATTACGATTGAACGTTCAGAAGTGGATGACATTATTGCAACTGAAGGCAAAGTGTCTCTTCATTGTGATTACTGTGGTAC
CAGTTACGACTTTGACAGCATTGATGTTGCTCATCTTTTTGAAGAAGCCACGAAAGGTAATGACACGGTTCATTAA

Upstream 100 bases:

>100_bases
GCAACAATAACTGACTTTCTTCTTTATTTACCTTTTCTCAAGGTTATAGCGGCTATAATAGCGATAACTGTAACCTCTAA
TACAATTGCTGGAGTATTTC

Downstream 100 bases:

>100_bases
TTCTTCATACAATTAATTCTTCATACAGAATAAGTTCTTTATTTTGTTTTAAAGCCAGCCATTAGGTTGGCTTTTTTTAT
GGATTTTTTTGATGTAAAGC

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MANNTLHRYLFEDLSVRGELVQLDDAYQQIISSKEYPKPVQNLLGELLVATTLLTATLKFEGSITLQLQGNGPVSLVVIN
GDNDQKVRGVARFEGEIADDATLHQLMGKGYLVITISPKDGERYQGVVALEGKDLAECFEGYFERSEQLKTRLWLRLGEF
EGKPHAAGMLLQVMPDGTGSSDDFEHLEQLTDTVKNEELFSLEAEDVLYRLYNQDKVQLFEPQNVEFFCGCSRERSGGAI
ITIERSEVDDIIATEGKVSLHCDYCGTSYDFDSIDVAHLFEEATKGNDTVH

Sequences:

>Translated_291_residues
MANNTLHRYLFEDLSVRGELVQLDDAYQQIISSKEYPKPVQNLLGELLVATTLLTATLKFEGSITLQLQGNGPVSLVVIN
GDNDQKVRGVARFEGEIADDATLHQLMGKGYLVITISPKDGERYQGVVALEGKDLAECFEGYFERSEQLKTRLWLRLGEF
EGKPHAAGMLLQVMPDGTGSSDDFEHLEQLTDTVKNEELFSLEAEDVLYRLYNQDKVQLFEPQNVEFFCGCSRERSGGAI
ITIERSEVDDIIATEGKVSLHCDYCGTSYDFDSIDVAHLFEEATKGNDTVH
>Mature_290_residues
ANNTLHRYLFEDLSVRGELVQLDDAYQQIISSKEYPKPVQNLLGELLVATTLLTATLKFEGSITLQLQGNGPVSLVVING
DNDQKVRGVARFEGEIADDATLHQLMGKGYLVITISPKDGERYQGVVALEGKDLAECFEGYFERSEQLKTRLWLRLGEFE
GKPHAAGMLLQVMPDGTGSSDDFEHLEQLTDTVKNEELFSLEAEDVLYRLYNQDKVQLFEPQNVEFFCGCSRERSGGAII
TIERSEVDDIIATEGKVSLHCDYCGTSYDFDSIDVAHLFEEATKGNDTVH

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=289, Percent_Identity=56.0553633217993, Blast_Score=355, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_ALISL (B6EGP6)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002264256.1
- ProteinModelPortal:   B6EGP6
- GeneID:   6988685
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2927
- HOGENOM:   HBG296531
- OMA:   AMTIDQG
- ProtClustDB:   PRK00114
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- InterPro:   IPR023212
- Gene3D:   G3DSA:1.10.287.480
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 32499; Mature: 32368

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANNTLHRYLFEDLSVRGELVQLDDAYQQIISSKEYPKPVQNLLGELLVATTLLTATLKF
CCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEE
EGSITLQLQGNGPVSLVVINGDNDQKVRGVARFEGEIADDATLHQLMGKGYLVITISPKD
CCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEECCC
GERYQGVVALEGKDLAECFEGYFERSEQLKTRLWLRLGEFEGKPHAAGMLLQVMPDGTGS
CCHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCC
SDDFEHLEQLTDTVKNEELFSLEAEDVLYRLYNQDKVQLFEPQNVEFFCGCSRERSGGAI
CHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCCCEE
ITIERSEVDDIIATEGKVSLHCDYCGTSYDFDSIDVAHLFEEATKGNDTVH
EEEECCCCCHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ANNTLHRYLFEDLSVRGELVQLDDAYQQIISSKEYPKPVQNLLGELLVATTLLTATLKF
CCCHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEE
EGSITLQLQGNGPVSLVVINGDNDQKVRGVARFEGEIADDATLHQLMGKGYLVITISPKD
CCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEECCC
GERYQGVVALEGKDLAECFEGYFERSEQLKTRLWLRLGEFEGKPHAAGMLLQVMPDGTGS
CCHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCC
SDDFEHLEQLTDTVKNEELFSLEAEDVLYRLYNQDKVQLFEPQNVEFFCGCSRERSGGAI
CHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCCCEE
ITIERSEVDDIIATEGKVSLHCDYCGTSYDFDSIDVAHLFEEATKGNDTVH
EEEECCCCCHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA