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The map label for this gene is nfuA

Identifier: 209696309

GI number: 209696309

Start: 3155939

End: 3156523

Strand: Reverse

Name: nfuA

Synonym: VSAL_I2911

Alternate gene names: 209696309

Gene position: 3156523-3155939 (Counterclockwise)

Preceding gene: 209696310

Following gene: 209696306

Centisome position: 94.93

GC content: 41.88

Gene sequence:

>585_bases
GTGACTTCAATCAATATTACTGAAAGTGCTCAAGAGCACTTTGCAAAACTTCTGGCACAACAGCCAGAGGGGACAAACAT
TCGTGTATTCGTGGTTAATCCAGGAACTCAAAATGCAGAGTGTGGCGTATCATATTGCCCACCGGAAGCGATTGAAGCGA
ACGATACTGAACTGAAATTTGAAAACTTATCTGCGTATGTAGATGAGCTAAGTTTGCCTTTCTTAGAAGATGCAGATATC
GATTACGTTACGGATAAAATGGGCTCTCAATTAACATTGAAAGCGCCTAACGCAAAAATGCGTAAAGTAAATGATGATGC
ACCTTTATTTGAACGTGTTGAATACGCGATTCAAACCCAAGTGAACCCTCAGCTTGCTGGCCATGGTGGTCACGTAAGTC
TAATGGAAATCACCGAAGCCGGTATTGCGATTGTTCAATTTGGTGGTGGCTGTAATGGTTGCTCGATGGTTGACGTGACA
TTAAAAGAAGGCATTGAAAAAGAGCTTTTAGCTCAATTTGAAGGTGAATTAACGGCGGTTAAAGATCTGACAGAGCATGA
TCGTGGTGAGCACTCTTACTACTAA

Upstream 100 bases:

>100_bases
AATTGATTATTAAGATTGGTATAATTTCGGTTCGATACTCGAAATTCAGTGTTTTTCAGAGTACAATCCTTAATCATACT
AATTTAGTCAGGTATTACTT

Downstream 100 bases:

>100_bases
TCAGAACGCTGATGTTGTAAAGGTGAGTATGTACTCACCTTTTTTGTGTCTATGGCATTATTATGAGATTAATTAAGCTT
AAGCGTTTGAGTAAATATCT

Product: DNA uptake protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MTSINITESAQEHFAKLLAQQPEGTNIRVFVVNPGTQNAECGVSYCPPEAIEANDTELKFENLSAYVDELSLPFLEDADI
DYVTDKMGSQLTLKAPNAKMRKVNDDAPLFERVEYAIQTQVNPQLAGHGGHVSLMEITEAGIAIVQFGGGCNGCSMVDVT
LKEGIEKELLAQFEGELTAVKDLTEHDRGEHSYY

Sequences:

>Translated_194_residues
MTSINITESAQEHFAKLLAQQPEGTNIRVFVVNPGTQNAECGVSYCPPEAIEANDTELKFENLSAYVDELSLPFLEDADI
DYVTDKMGSQLTLKAPNAKMRKVNDDAPLFERVEYAIQTQVNPQLAGHGGHVSLMEITEAGIAIVQFGGGCNGCSMVDVT
LKEGIEKELLAQFEGELTAVKDLTEHDRGEHSYY
>Mature_193_residues
TSINITESAQEHFAKLLAQQPEGTNIRVFVVNPGTQNAECGVSYCPPEAIEANDTELKFENLSAYVDELSLPFLEDADID
YVTDKMGSQLTLKAPNAKMRKVNDDAPLFERVEYAIQTQVNPQLAGHGGHVSLMEITEAGIAIVQFGGGCNGCSMVDVTL
KEGIEKELLAQFEGELTAVKDLTEHDRGEHSYY

Specific function: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins

COG id: COG0694

COG function: function code O; Thioredoxin-like proteins and domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nfuA family

Homologues:

Organism=Escherichia coli, GI1789819, Length=191, Percent_Identity=78.0104712041885, Blast_Score=315, Evalue=1e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NFUA_ALISL (B6ENV8)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002264240.1
- GeneID:   6989080
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2911
- HOGENOM:   HBG289644
- OMA:   CQGCSAV
- ProtClustDB:   PRK11190
- HAMAP:   MF_01637
- InterPro:   IPR017726
- InterPro:   IPR000361
- InterPro:   IPR001075
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- ProDom:   PD002830
- TIGRFAMs:   TIGR03341

Pfam domain/function: PF01521 Fe-S_biosyn; PF01106 NifU; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 21241; Mature: 21110

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSINITESAQEHFAKLLAQQPEGTNIRVFVVNPGTQNAECGVSYCPPEAIEANDTELKF
CCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEECCCCCCCCCCCEEEH
ENLSAYVDELSLPFLEDADIDYVTDKMGSQLTLKAPNAKMRKVNDDAPLFERVEYAIQTQ
HHHHHHHHHCCCCCCCCCCCCHHHHCCCCEEEEECCCCHHEECCCCCHHHHHHHHHHHCC
VNPQLAGHGGHVSLMEITEAGIAIVQFGGGCNGCSMVDVTLKEGIEKELLAQFEGELTAV
CCCEECCCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEHHHCCHHHHHHHHHCCCHHHH
KDLTEHDRGEHSYY
HHHHHHCCCCCCCC
>Mature Secondary Structure 
TSINITESAQEHFAKLLAQQPEGTNIRVFVVNPGTQNAECGVSYCPPEAIEANDTELKF
CCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEECCCCCCCCCCCEEEH
ENLSAYVDELSLPFLEDADIDYVTDKMGSQLTLKAPNAKMRKVNDDAPLFERVEYAIQTQ
HHHHHHHHHCCCCCCCCCCCCHHHHCCCCEEEEECCCCHHEECCCCCHHHHHHHHHHHCC
VNPQLAGHGGHVSLMEITEAGIAIVQFGGGCNGCSMVDVTLKEGIEKELLAQFEGELTAV
CCCEECCCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEHHHCCHHHHHHHHHCCCHHHH
KDLTEHDRGEHSYY
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA