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The map label for this gene is cysQ [H]

Identifier: 209696310

GI number: 209696310

Start: 3156642

End: 3157460

Strand: Reverse

Name: cysQ [H]

Synonym: VSAL_I2912

Alternate gene names: 209696310

Gene position: 3157460-3156642 (Counterclockwise)

Preceding gene: 209696311

Following gene: 209696309

Centisome position: 94.96

GC content: 41.27

Gene sequence:

>819_bases
ATGGATTCTACGTTTTCACATCTTCTTCCTGACGTGATCAAAATTGCTCGCGCTTCAGGTCAATTGATTTTAGATATCTA
TGAAAAAGGCGATTTTGAAGCGTTTATTAAAGCGGATCAAACGCCAGTGACAAGTGCGGATTTAGCTGCTCATAAATTGA
TCATGGAAAAGCTGTCTCAACTGACGCCTGATATTCCAATTTTATCTGAAGAAGACGCGAATGTGTCTTTAGAACAACGT
TCTCAGTGGGAGCGCTATTGGTTAGTTGATCCGCTTGATGGAACTCAAGAGTTTATTGCTCGTAGTGGTGATTTTGCTAC
CATTATTGCATTGGTTGAAAATAACCGTCCTATTATGGGGGTTGTTTATGCGCCGGTTTCTGGTGTCACTTATTATGCTT
ATGAAGGTAAAGGTGCATGGAAAATCCCTGATATGGATGAAAGTGTGCGAATTAGCACGCTTAAGCATGAAGAAGAGAAA
CAGCCAATTGCGGTTGCGATAAGTCGTCGCCAAAACATTAATAACATTACTCGCTGTATGAGTTCTGAATGGAATTATGA
TTTAGTGCCATTGGGATCCGCCGCCTTAAAAGCCTGTTTGGTTGCAGAAGGTGCTGTCGATTGTTATTTACGTTTGGGGC
CAACAGGCGAGTGGGATACCGCAGCAACACAATGTATTGTTCAAGAAGCGGGTGGTCGTATATTATCAACCAAGCTTGAA
CCACTGTCGTACAATGAACGAGAGTCGTTAGAGAACCCTAATTTTATTGTATTAGGTGACGAGAATCTTCCATGGGATTC
TATTTTAACTTGTGAATAA

Upstream 100 bases:

>100_bases
GTCAAGCGTCTGAATTACTTCATCATCTCGATTTTTCAGAAGCAAGGTGCATTAGTGCATTATTGCTTGCTCAACAATTT
TTAGAAAAGGAGTGATATTG

Downstream 100 bases:

>100_bases
TGAGCACCAATCTTGATAAATTGATTATTAAGATTGGTATAATTTCGGTTCGATACTCGAAATTCAGTGTTTTTCAGAGT
ACAATCCTTAATCATACTAA

Product: protein CysQ

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MDSTFSHLLPDVIKIARASGQLILDIYEKGDFEAFIKADQTPVTSADLAAHKLIMEKLSQLTPDIPILSEEDANVSLEQR
SQWERYWLVDPLDGTQEFIARSGDFATIIALVENNRPIMGVVYAPVSGVTYYAYEGKGAWKIPDMDESVRISTLKHEEEK
QPIAVAISRRQNINNITRCMSSEWNYDLVPLGSAALKACLVAEGAVDCYLRLGPTGEWDTAATQCIVQEAGGRILSTKLE
PLSYNERESLENPNFIVLGDENLPWDSILTCE

Sequences:

>Translated_272_residues
MDSTFSHLLPDVIKIARASGQLILDIYEKGDFEAFIKADQTPVTSADLAAHKLIMEKLSQLTPDIPILSEEDANVSLEQR
SQWERYWLVDPLDGTQEFIARSGDFATIIALVENNRPIMGVVYAPVSGVTYYAYEGKGAWKIPDMDESVRISTLKHEEEK
QPIAVAISRRQNINNITRCMSSEWNYDLVPLGSAALKACLVAEGAVDCYLRLGPTGEWDTAATQCIVQEAGGRILSTKLE
PLSYNERESLENPNFIVLGDENLPWDSILTCE
>Mature_272_residues
MDSTFSHLLPDVIKIARASGQLILDIYEKGDFEAFIKADQTPVTSADLAAHKLIMEKLSQLTPDIPILSEEDANVSLEQR
SQWERYWLVDPLDGTQEFIARSGDFATIIALVENNRPIMGVVYAPVSGVTYYAYEGKGAWKIPDMDESVRISTLKHEEEK
QPIAVAISRRQNINNITRCMSSEWNYDLVPLGSAALKACLVAEGAVDCYLRLGPTGEWDTAATQCIVQEAGGRILSTKLE
PLSYNERESLENPNFIVLGDENLPWDSILTCE

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=255, Percent_Identity=25.0980392156863, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI221625487, Length=255, Percent_Identity=25.0980392156863, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI7657236, Length=207, Percent_Identity=26.5700483091787, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1790659, Length=251, Percent_Identity=43.8247011952191, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1788882, Length=235, Percent_Identity=33.1914893617021, Blast_Score=87, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI193202572, Length=250, Percent_Identity=27.6, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71995897, Length=281, Percent_Identity=24.5551601423488, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71995905, Length=281, Percent_Identity=24.5551601423488, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320493, Length=199, Percent_Identity=27.6381909547739, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321836, Length=206, Percent_Identity=28.1553398058252, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24664922, Length=230, Percent_Identity=30, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24664926, Length=232, Percent_Identity=27.1551724137931, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641722, Length=274, Percent_Identity=24.4525547445255, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24664918, Length=272, Percent_Identity=23.5294117647059, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 30271; Mature: 30271

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTFSHLLPDVIKIARASGQLILDIYEKGDFEAFIKADQTPVTSADLAAHKLIMEKLSQ
CCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
LTPDIPILSEEDANVSLEQRSQWERYWLVDPLDGTQEFIARSGDFATIIALVENNRPIMG
HCCCCCEECCCCCCCCHHHHCCCCEEEEECCCCCHHHHHHCCCCEEEEEEEEECCCCEEE
VVYAPVSGVTYYAYEGKGAWKIPDMDESVRISTLKHEEEKQPIAVAISRRQNINNITRCM
EEEECCCCEEEEEECCCCCEECCCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHH
SSEWNYDLVPLGSAALKACLVAEGAVDCYLRLGPTGEWDTAATQCIVQEAGGRILSTKLE
CCCCCEEEEECCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEECC
PLSYNERESLENPNFIVLGDENLPWDSILTCE
CCCCCHHHCCCCCCEEEECCCCCCCCCEEECC
>Mature Secondary Structure
MDSTFSHLLPDVIKIARASGQLILDIYEKGDFEAFIKADQTPVTSADLAAHKLIMEKLSQ
CCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
LTPDIPILSEEDANVSLEQRSQWERYWLVDPLDGTQEFIARSGDFATIIALVENNRPIMG
HCCCCCEECCCCCCCCHHHHCCCCEEEEECCCCCHHHHHHCCCCEEEEEEEEECCCCEEE
VVYAPVSGVTYYAYEGKGAWKIPDMDESVRISTLKHEEEKQPIAVAISRRQNINNITRCM
EEEECCCCEEEEEECCCCCEECCCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHH
SSEWNYDLVPLGSAALKACLVAEGAVDCYLRLGPTGEWDTAATQCIVQEAGGRILSTKLE
CCCCCEEEEECCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEECC
PLSYNERESLENPNFIVLGDENLPWDSILTCE
CCCCCHHHCCCCCCEEEECCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]