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The map label for this gene is recG [H]

Identifier: 209696308

GI number: 209696308

Start: 3153779

End: 3155860

Strand: Direct

Name: recG [H]

Synonym: VSAL_I2910

Alternate gene names: 209696308

Gene position: 3153779-3155860 (Clockwise)

Preceding gene: 209696307

Following gene: 209696324

Centisome position: 94.85

GC content: 42.6

Gene sequence:

>2082_bases
ATGACCAACCAATTACTTTCAGCCACCCCATTAACCTCTCTGGCTGGTGTCGGCGCGAAAGTAGCCGAAAAGCTGGCTAA
AATTGGTTTGGTTACTATCCAAGATTTACTTTTTCACCTGCCTCTACGCTATGAAGATCGAACCAAAGTCTACCCAATAG
CACGTGTTCATGCCGGCTTATTTGCCGCAGTACAAGGCAATGTCATGTCTTGTGATCTTCAATTTGGCAAAAGAAAAATG
CTGTTAGTAAAAATCAGTGATGGCAACGGAACGATTACATTGCGCTTTTTCAATTTTAATGCGGGAATGAAAAACCATTT
TAGTGAAGGTAAATTAGTCCATGCTTACGGAGAGATAAAACGAGGTGGTGTAGGTTTAGAAATTGTTCATCCTGATTATC
AATTTCATACACCCTCTAAACCTTTAGACATTGAAGCAACATTAACCCCCGTTTACCCTGCGACTGATGGTCTTCGCCAA
AACACACTCCGCAGCCTTACCGATCAAGCACTTGTACTCTTAGACAAAGCCGCGGTCACCGAATTGTTACCACAAGGGTT
ATACAATAATCAAATAACGCTAAATCAAGCGTTGCATATTATTCATCGCCCTGATCCTTCAATTAACTTAGAAGCGTTTG
ATCAAGGAAAGCATCCAGCACAACAACGATTGATTATTGAAGAATTATTAGCACAGAACCTATCTATGCTATCGGTACGC
AGTAAAGGCCAGCAAGAAAATGCGTTACCACTAACAACAAGAAGTAATCTAAAGCAAAAATTATTAGCACAGCTCCCCTT
CACCCCAACAAATACACAACAGCGAGTCGTGGCTGAAATAGAACACGATTTAGCAAAACCACACCCAATGATGCGCTTAG
TTCAAGGGGATGTTGGCTCAGGTAAAACCCTTGTCTCTGCATTAGCCGCAGTACAAGCCATAGAACATGGTTACCAGGTT
GCATTAATGGCCCCTACAGAGCTGTTAGCAGAACAACACGCCATTAACTTTACCAAGTGGTTTGAGAGCATGGGTATCCC
TGTTGGGTGGCTAGCAGGAAAGCTAACGGGAAAAGCGAAAGAAAAAGAATTAACCCGTATTGCTAGCGGTGAAGCAAAAA
TGATAGTGGGCACTCACGCACTTTTCCAACAACATGTTCAATTTCACCATCTCGCGTTGGTGATTATCGATGAACAACAT
CGTTTTGGTGTTGACCAACGTCTAGAGCTACGAGAAAAGGGGCTAAAAAATGGGGCTTATCCACATCAATTAATCATGAC
AGCAACGCCAATACCTCGAACCTTGGCAATGACAGCGTATGCTGATCTTGAAACCTCTGTAATTGATGAATTACCGCCGG
GAAGAACACCAATTCAAACGGTCGCGGTTCCTGATACCCGCCGAAGCGAGATCGTGGATAAAGTAAAAACAGCCTGTCTT
GAAGATGGACGTCAAGCCTACTGGGTATGTACGTTAATCGATGATTCAGAAGTACTAGAGGCACAAGCTGCATCAGACAC
AGCAGAATCACTTCGCTTACAACTACCAGAACTTAATATTGGTTTAGTTCATGGCAGAATGAAATCGCAAGAAAAACAGC
GCATCATGCAAGAATTCAAAGAAGGTAAGCTACATTTGTTAGTAGCCACTACCGTTATTGAAGTCGGTGTCGATGTACCA
AATTCAAGCTTAATGATCATAGAGAACCCAGAAAGATTAGGTCTTGCTCAATTACATCAATTACGAGGCCGTGTTGGTCG
AGGAACAGTAGCAAGTCACTGCGTTCTGCTTTATCACGCCCCATTATCTAAAACGGCACAAAAGCGATTAAGTGTGCTAC
GCGAAAGTAATGATGGCTTTGTCATCGCACAACGAGATTTAGAAATTCGTGGGCCCGGTGAGTTATTAGGAACAAAACAA
ACAGGATTAGCGGATTTTAAAATTGCCGATTTAGTTCGAGATCAACACTTAATCCCTGAAGTCCAACGCATTGCACGTTA
TATTCATGACAGTTACCCAAGTAATGCAAAAGCCATTATTCAGCGCTGGCTTGGCGAACGAGATATTTACTCAAACGCTT
AA

Upstream 100 bases:

>100_bases
TTTTTAATGCTCTAAACCCTGGCGATAAAGGTATAATGACTTATCAAGGACGTAAGTTTCATCACTTTGCGTTAAAGCGA
GACTAATTTCAGGGACACAT

Downstream 100 bases:

>100_bases
GCTTAATTAATCTCATAATAATGCCATAGACACAAAAAAGGTGAGTACATACTCACCTTTACAACATCAGCGTTCTGATT
AGTAGTAAGAGTGCTCACCA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MTNQLLSATPLTSLAGVGAKVAEKLAKIGLVTIQDLLFHLPLRYEDRTKVYPIARVHAGLFAAVQGNVMSCDLQFGKRKM
LLVKISDGNGTITLRFFNFNAGMKNHFSEGKLVHAYGEIKRGGVGLEIVHPDYQFHTPSKPLDIEATLTPVYPATDGLRQ
NTLRSLTDQALVLLDKAAVTELLPQGLYNNQITLNQALHIIHRPDPSINLEAFDQGKHPAQQRLIIEELLAQNLSMLSVR
SKGQQENALPLTTRSNLKQKLLAQLPFTPTNTQQRVVAEIEHDLAKPHPMMRLVQGDVGSGKTLVSALAAVQAIEHGYQV
ALMAPTELLAEQHAINFTKWFESMGIPVGWLAGKLTGKAKEKELTRIASGEAKMIVGTHALFQQHVQFHHLALVIIDEQH
RFGVDQRLELREKGLKNGAYPHQLIMTATPIPRTLAMTAYADLETSVIDELPPGRTPIQTVAVPDTRRSEIVDKVKTACL
EDGRQAYWVCTLIDDSEVLEAQAASDTAESLRLQLPELNIGLVHGRMKSQEKQRIMQEFKEGKLHLLVATTVIEVGVDVP
NSSLMIIENPERLGLAQLHQLRGRVGRGTVASHCVLLYHAPLSKTAQKRLSVLRESNDGFVIAQRDLEIRGPGELLGTKQ
TGLADFKIADLVRDQHLIPEVQRIARYIHDSYPSNAKAIIQRWLGERDIYSNA

Sequences:

>Translated_693_residues
MTNQLLSATPLTSLAGVGAKVAEKLAKIGLVTIQDLLFHLPLRYEDRTKVYPIARVHAGLFAAVQGNVMSCDLQFGKRKM
LLVKISDGNGTITLRFFNFNAGMKNHFSEGKLVHAYGEIKRGGVGLEIVHPDYQFHTPSKPLDIEATLTPVYPATDGLRQ
NTLRSLTDQALVLLDKAAVTELLPQGLYNNQITLNQALHIIHRPDPSINLEAFDQGKHPAQQRLIIEELLAQNLSMLSVR
SKGQQENALPLTTRSNLKQKLLAQLPFTPTNTQQRVVAEIEHDLAKPHPMMRLVQGDVGSGKTLVSALAAVQAIEHGYQV
ALMAPTELLAEQHAINFTKWFESMGIPVGWLAGKLTGKAKEKELTRIASGEAKMIVGTHALFQQHVQFHHLALVIIDEQH
RFGVDQRLELREKGLKNGAYPHQLIMTATPIPRTLAMTAYADLETSVIDELPPGRTPIQTVAVPDTRRSEIVDKVKTACL
EDGRQAYWVCTLIDDSEVLEAQAASDTAESLRLQLPELNIGLVHGRMKSQEKQRIMQEFKEGKLHLLVATTVIEVGVDVP
NSSLMIIENPERLGLAQLHQLRGRVGRGTVASHCVLLYHAPLSKTAQKRLSVLRESNDGFVIAQRDLEIRGPGELLGTKQ
TGLADFKIADLVRDQHLIPEVQRIARYIHDSYPSNAKAIIQRWLGERDIYSNA
>Mature_692_residues
TNQLLSATPLTSLAGVGAKVAEKLAKIGLVTIQDLLFHLPLRYEDRTKVYPIARVHAGLFAAVQGNVMSCDLQFGKRKML
LVKISDGNGTITLRFFNFNAGMKNHFSEGKLVHAYGEIKRGGVGLEIVHPDYQFHTPSKPLDIEATLTPVYPATDGLRQN
TLRSLTDQALVLLDKAAVTELLPQGLYNNQITLNQALHIIHRPDPSINLEAFDQGKHPAQQRLIIEELLAQNLSMLSVRS
KGQQENALPLTTRSNLKQKLLAQLPFTPTNTQQRVVAEIEHDLAKPHPMMRLVQGDVGSGKTLVSALAAVQAIEHGYQVA
LMAPTELLAEQHAINFTKWFESMGIPVGWLAGKLTGKAKEKELTRIASGEAKMIVGTHALFQQHVQFHHLALVIIDEQHR
FGVDQRLELREKGLKNGAYPHQLIMTATPIPRTLAMTAYADLETSVIDELPPGRTPIQTVAVPDTRRSEIVDKVKTACLE
DGRQAYWVCTLIDDSEVLEAQAASDTAESLRLQLPELNIGLVHGRMKSQEKQRIMQEFKEGKLHLLVATTVIEVGVDVPN
SSLMIIENPERLGLAQLHQLRGRVGRGTVASHCVLLYHAPLSKTAQKRLSVLRESNDGFVIAQRDLEIRGPGELLGTKQT
GLADFKIADLVRDQHLIPEVQRIARYIHDSYPSNAKAIIQRWLGERDIYSNA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=693, Percent_Identity=67.0995670995671, Blast_Score=945, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=389, Percent_Identity=38.0462724935733, Blast_Score=236, Evalue=4e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76795; Mature: 76664

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQLLSATPLTSLAGVGAKVAEKLAKIGLVTIQDLLFHLPLRYEDRTKVYPIARVHAGL
CCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHH
FAAVQGNVMSCDLQFGKRKMLLVKISDGNGTITLRFFNFNAGMKNHFSEGKLVHAYGEIK
HEEECCCEEEEEEECCCCEEEEEEEECCCCEEEEEEEEECCCCCCCCCCCCEEEEECCCC
RGGVGLEIVHPDYQFHTPSKPLDIEATLTPVYPATDGLRQNTLRSLTDQALVLLDKAAVT
CCCCEEEEECCCCEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ELLPQGLYNNQITLNQALHIIHRPDPSINLEAFDQGKHPAQQRLIIEELLAQNLSMLSVR
HHHHCCCCCCEEEHHHHEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHH
SKGQQENALPLTTRSNLKQKLLAQLPFTPTNTQQRVVAEIEHDLAKPHPMMRLVQGDVGS
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCC
GKTLVSALAAVQAIEHGYQVALMAPTELLAEQHAINFTKWFESMGIPVGWLAGKLTGKAK
CHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCHHHHHHHHHCCCHHHHHHCCCCCHH
EKELTRIASGEAKMIVGTHALFQQHVQFHHLALVIIDEQHRFGVDQRLELREKGLKNGAY
HHHHHHHHCCCCEEEEEHHHHHHHHHHHEEEEEEEEECHHHCCCCHHHHHHHCCCCCCCC
PHQLIMTATPIPRTLAMTAYADLETSVIDELPPGRTPIQTVAVPDTRRSEIVDKVKTACL
CCEEEEECCCCCHHHHHHHHHCCHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
EDGRQAYWVCTLIDDSEVLEAQAASDTAESLRLQLPELNIGLVHGRMKSQEKQRIMQEFK
HCCCEEEEEEEEECCHHHHHHHHCCCCHHHHEEECCCCCEEEEECHHHHHHHHHHHHHHH
EGKLHLLVATTVIEVGVDVPNSSLMIIENPERLGLAQLHQLRGRVGRGTVASHCVLLYHA
CCCEEEEEEEEHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCHHHCEEEEEEC
PLSKTAQKRLSVLRESNDGFVIAQRDLEIRGPGELLGTKQTGLADFKIADLVRDQHLIPE
CCHHHHHHHHHHHHCCCCCEEEEECCEEECCCHHHCCCCCCCCCCHHHHHHHHHHHCCHH
VQRIARYIHDSYPSNAKAIIQRWLGERDIYSNA
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TNQLLSATPLTSLAGVGAKVAEKLAKIGLVTIQDLLFHLPLRYEDRTKVYPIARVHAGL
CCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHH
FAAVQGNVMSCDLQFGKRKMLLVKISDGNGTITLRFFNFNAGMKNHFSEGKLVHAYGEIK
HEEECCCEEEEEEECCCCEEEEEEEECCCCEEEEEEEEECCCCCCCCCCCCEEEEECCCC
RGGVGLEIVHPDYQFHTPSKPLDIEATLTPVYPATDGLRQNTLRSLTDQALVLLDKAAVT
CCCCEEEEECCCCEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ELLPQGLYNNQITLNQALHIIHRPDPSINLEAFDQGKHPAQQRLIIEELLAQNLSMLSVR
HHHHCCCCCCEEEHHHHEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHH
SKGQQENALPLTTRSNLKQKLLAQLPFTPTNTQQRVVAEIEHDLAKPHPMMRLVQGDVGS
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCC
GKTLVSALAAVQAIEHGYQVALMAPTELLAEQHAINFTKWFESMGIPVGWLAGKLTGKAK
CHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCHHHHHHHHHCCCHHHHHHCCCCCHH
EKELTRIASGEAKMIVGTHALFQQHVQFHHLALVIIDEQHRFGVDQRLELREKGLKNGAY
HHHHHHHHCCCCEEEEEHHHHHHHHHHHEEEEEEEEECHHHCCCCHHHHHHHCCCCCCCC
PHQLIMTATPIPRTLAMTAYADLETSVIDELPPGRTPIQTVAVPDTRRSEIVDKVKTACL
CCEEEEECCCCCHHHHHHHHHCCHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
EDGRQAYWVCTLIDDSEVLEAQAASDTAESLRLQLPELNIGLVHGRMKSQEKQRIMQEFK
HCCCEEEEEEEEECCHHHHHHHHCCCCHHHHEEECCCCCEEEEECHHHHHHHHHHHHHHH
EGKLHLLVATTVIEVGVDVPNSSLMIIENPERLGLAQLHQLRGRVGRGTVASHCVLLYHA
CCCEEEEEEEEHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCHHHCEEEEEEC
PLSKTAQKRLSVLRESNDGFVIAQRDLEIRGPGELLGTKQTGLADFKIADLVRDQHLIPE
CCHHHHHHHHHHHHCCCCCEEEEECCEEECCCHHHCCCCCCCCCCHHHHHHHHHHHCCHH
VQRIARYIHDSYPSNAKAIIQRWLGERDIYSNA
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]