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The map label for this gene is prmA

Identifier: 209696241

GI number: 209696241

Start: 3076378

End: 3077262

Strand: Direct

Name: prmA

Synonym: VSAL_I2837

Alternate gene names: 209696241

Gene position: 3076378-3077262 (Clockwise)

Preceding gene: 209696240

Following gene: 209696242

Centisome position: 92.52

GC content: 44.07

Gene sequence:

>885_bases
ATGCCTTGGATTCAAGTAAAACTAAATGCAACATCTGAAAATGCTGAACTAATCAGTGACATGCTAGTAGAAGAGACCGG
TGCTCTTTCTGTTACATTTTTAGATGCTAAAGATACCCCGATCTTTGAACCTCTTCCTGGAGAGACTCGCTTATGGGGTG
AAACGGACATTGTTGCTCTTTATGATGCAGAAACCGACATGGATTTAGTCATTACACAATTGAAAGCAAGCGCCGTACTT
GATGACAACTTTGCCTACAAAATAGAGCAACTTGAAGATAAAGACTGGGAACGCGAATGGATGGATAACTTCCACCCAAT
GAAATTTGGTGAGCGCTTGTGGATTTGCCCAAGCTGGCGTGAAATTCCAGAGCCAGACGCGATTAACGTCATGCTTGATC
CTGGCCTTGCATTTGGCACAGGAACGCATGCAACAACCGCACTTTGTCTTGAATGGCTAGAAAGCATCGATCTTACTGGT
AAAACAGTTATCGACTTCGGTTGTGGTTCTGGCATCTTAGCGATCGCCGCTATCAAACTAGGCGCAGCGAAAGTGGTTGG
GATCGATATAGATCCTCAAGCGATCACAGCATCAAAAGACAATGCAACTCGCAATGGTGTTGCTGAACAACTAACGCTTT
TCCTTCCTCAAGACCAACCAGAAAACCTTGTCGCTGACGTTGTTGTTGCTAATATTCTTGCAGCCCCTTTACGTGAACTT
TCAAGTATAATTACCGCTCATGTGAAGCCTGGAGGCGCACTAGCTATGTCTGGTGTACTCGATACTCAAGCAAATAATGT
CGCTTCATACTACTCAGACAACTTCACTCTTGATGCGATTGCAGAGCAACAAGAATGGTGCAGAATCTCAGGAATTAAGA
AGTAA

Upstream 100 bases:

>100_bases
TTTAAGTTAAAGACATAAATAAAGGCCATGAGTGATTATACTCATGGCCTTTTTCTATGATAAAATTCGCCGATATTTTC
AACTAAATAAAGTGATCCCC

Downstream 100 bases:

>100_bases
CGGCCTCTAAGACCTACTCTTCCTAGAAAAAACTTCAATGCCTCAATACTAAATTTGAGGCATAAAACCATCTAATTGAC
TGAAATATAAACAAATTACA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MPWIQVKLNATSENAELISDMLVEETGALSVTFLDAKDTPIFEPLPGETRLWGETDIVALYDAETDMDLVITQLKASAVL
DDNFAYKIEQLEDKDWEREWMDNFHPMKFGERLWICPSWREIPEPDAINVMLDPGLAFGTGTHATTALCLEWLESIDLTG
KTVIDFGCGSGILAIAAIKLGAAKVVGIDIDPQAITASKDNATRNGVAEQLTLFLPQDQPENLVADVVVANILAAPLREL
SSIITAHVKPGGALAMSGVLDTQANNVASYYSDNFTLDAIAEQQEWCRISGIKK

Sequences:

>Translated_294_residues
MPWIQVKLNATSENAELISDMLVEETGALSVTFLDAKDTPIFEPLPGETRLWGETDIVALYDAETDMDLVITQLKASAVL
DDNFAYKIEQLEDKDWEREWMDNFHPMKFGERLWICPSWREIPEPDAINVMLDPGLAFGTGTHATTALCLEWLESIDLTG
KTVIDFGCGSGILAIAAIKLGAAKVVGIDIDPQAITASKDNATRNGVAEQLTLFLPQDQPENLVADVVVANILAAPLREL
SSIITAHVKPGGALAMSGVLDTQANNVASYYSDNFTLDAIAEQQEWCRISGIKK
>Mature_293_residues
PWIQVKLNATSENAELISDMLVEETGALSVTFLDAKDTPIFEPLPGETRLWGETDIVALYDAETDMDLVITQLKASAVLD
DNFAYKIEQLEDKDWEREWMDNFHPMKFGERLWICPSWREIPEPDAINVMLDPGLAFGTGTHATTALCLEWLESIDLTGK
TVIDFGCGSGILAIAAIKLGAAKVVGIDIDPQAITASKDNATRNGVAEQLTLFLPQDQPENLVADVVVANILAAPLRELS
SIITAHVKPGGALAMSGVLDTQANNVASYYSDNFTLDAIAEQQEWCRISGIKK

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=294, Percent_Identity=68.0272108843537, Blast_Score=396, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_ALISL (B6ENA3)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002264171.1
- ProteinModelPortal:   B6ENA3
- GeneID:   6988211
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2837
- HOGENOM:   HBG584653
- OMA:   EDQDWER
- ProtClustDB:   PRK00517
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32109; Mature: 31978

Theoretical pI: Translated: 4.01; Mature: 4.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWIQVKLNATSENAELISDMLVEETGALSVTFLDAKDTPIFEPLPGETRLWGETDIVAL
CCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCEEEE
YDAETDMDLVITQLKASAVLDDNFAYKIEQLEDKDWEREWMDNFHPMKFGERLWICPSWR
EECCCCHHHHHHHHHHHHEECCCCEEEEEHHCCCCHHHHHHCCCCCCCCCCEEEECCCCC
EIPEPDAINVMLDPGLAFGTGTHATTALCLEWLESIDLTGKTVIDFGCGSGILAIAAIKL
CCCCCCEEEEEECCCCEECCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHH
GAAKVVGIDIDPQAITASKDNATRNGVAEQLTLFLPQDQPENLVADVVVANILAAPLREL
CCEEEEEEECCCCEEECCCCCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
SSIITAHVKPGGALAMSGVLDTQANNVASYYSDNFTLDAIAEQQEWCRISGIKK
HHHHEEECCCCCCEEECCEECCCCCCHHHHHCCCCEEEHHHCHHHHHHHCCCCC
>Mature Secondary Structure 
PWIQVKLNATSENAELISDMLVEETGALSVTFLDAKDTPIFEPLPGETRLWGETDIVAL
CEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCEEEE
YDAETDMDLVITQLKASAVLDDNFAYKIEQLEDKDWEREWMDNFHPMKFGERLWICPSWR
EECCCCHHHHHHHHHHHHEECCCCEEEEEHHCCCCHHHHHHCCCCCCCCCCEEEECCCCC
EIPEPDAINVMLDPGLAFGTGTHATTALCLEWLESIDLTGKTVIDFGCGSGILAIAAIKL
CCCCCCEEEEEECCCCEECCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHH
GAAKVVGIDIDPQAITASKDNATRNGVAEQLTLFLPQDQPENLVADVVVANILAAPLREL
CCEEEEEEECCCCEEECCCCCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
SSIITAHVKPGGALAMSGVLDTQANNVASYYSDNFTLDAIAEQQEWCRISGIKK
HHHHEEECCCCCCEEECCEECCCCCCHHHHHCCCCEEEHHHCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA