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The map label for this gene is hlyB [H]

Identifier: 209696086

GI number: 209696086

Start: 2899652

End: 2901253

Strand: Reverse

Name: hlyB [H]

Synonym: VSAL_I2678

Alternate gene names: 209696086

Gene position: 2901253-2899652 (Counterclockwise)

Preceding gene: 209696088

Following gene: 209696085

Centisome position: 87.25

GC content: 41.7

Gene sequence:

>1602_bases
ATGCCCGTAATAACATTTAAGCCATGGGAAAGGCTGGTAACTGATATTAAGTTAGTCCCTAAATTGGTCATGTTAATGGT
ATTTAGTACCGTTTTGTTAGTATCAAAACAATTATGGGATGCAAATACGTTCTATCATGCCGTTATTGATGTTCAAAAAG
AAAGCGCACAAAGCGCTGCGACAGCGAATGCAGAATTAATTAACGGTATTTTAAACAGCCAATCGGGCAATCAGCAATTG
GTGGCAGAGGCCATCACCGCTCAAGCAAAGGCATGGACCACCGGAAACTACATTTACGCGATTGATCGTAATAGTGGGGA
AGTCTTTGGCCATAAATCGATTCAATCGTTGTCTTCATTAACAGGATCTATTGATGGTGGAAACTCCGTTAACCAACTCT
TGCGTAATGTATCGTCTCAGCAAGCGTATTCCCTTAATGATAATACTCGCTATGAGTTTGCCGTAAAAGTGGCAAATCAT
AATTGGGTTGTTGCTTCTTCATTAACAACAAAAGGTGCAGAGGCTTATTATCAAGAATATTTGATGCAAGTGATTTGGCA
GACCATTGCCATGATTGTTGCTTTTATGGTTATTCTGTTGGGTGCTTCAAGCATTATGCTGCGCCAAATGCGTTACTTGA
ACAGTTCAATGAAAGAGATTGCGGCGCAAAATTTATCGCTACCTGTTGAGATGAATTGCAAAGATGAATTTGGTGATCTA
GCAAGAGAATTAGATAAAACGCGTTTACAGCTTAAATCGGTTGTGGAGAATCAATTATCGGCATCTCAAGAGTTGGCCAG
TTTGACTGAAATCATGACGATAAGCATGGAAGGAACAAAAGAAGCGGCCCAAGAAGAGTTTGCAGAAATTGATCAGCTAG
CGACAGCAATGAGTGAAATGAATTCTACGGTTCAAAACGTAGCAGAAAATGCGCGCAGTGCCTCTATAGGGACAGAGCAA
GCTAAAATCCAAGCAAAAATAGGTCAAGAATTTGTTCAAGGGACCATCATTAAAATTCAAGCACTGTCTGGTGATATAGC
GGCTTCTGCTGAAGTGGTTAATCAAGTAGAAGAACGAGTAATATCCATTAGTTCAGTGGTTGAGACGATTCGTGGCATCT
CAGAACAAACGAATTTATTAGCATTAAACGCGGCAATTGAAGCGGCACGCGCAGGTGATGCTGGTCGAGGTTTTGCGGTC
GTTGCTGATGAAGTGAGAAACCTAGCACAGAGCACACAAGGTGCAACGGTTGAGATCCAAGAAATGATCACTCAGCTTCA
AAACAGCGCGAATCAAGCCGTTGACCTAATGGAAAAAAGTGTGGTTGAAGCGGCTGAAGGCGTGGAATTGGTGACGAATG
CTGGGACAGAACTAGACAGCATTGTGAATCAAGTGAATAACATTAATGAAATGAACTTCCAAATCGCGAGTGCTGCGGAG
CAACAAAGCAGTGTGGCTGAAGAAATGGATCAGAACCTAACGAATGTTCGTGAACTGGTTGAAGCGTCAGTGGTTGTAAT
GACAGAGCTAACCGAAACCTCAGAAGAAATGAAGAAGAATGCTGAAGATCTCGAAAGTAAAATGAAGATGTTTAAGATCT
AG

Upstream 100 bases:

>100_bases
ATATGTATCTCAGTAGATATAAAAAATGTGCACATAGGCTTGCACAGCTTGCTCCATGATGCACTAAATAATCAGAGACT
TAAAGGAATGAGGAAATGCT

Downstream 100 bases:

>100_bases
TTTACGACGGTCTCTTTTTTTATGAACGCCCGCACTCAGTTGTGGGCGTTTTTGTTTGCGACAAAATACAAAGTTTGGCA
CAGTGTTAGCATTACCTTTG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MPVITFKPWERLVTDIKLVPKLVMLMVFSTVLLVSKQLWDANTFYHAVIDVQKESAQSAATANAELINGILNSQSGNQQL
VAEAITAQAKAWTTGNYIYAIDRNSGEVFGHKSIQSLSSLTGSIDGGNSVNQLLRNVSSQQAYSLNDNTRYEFAVKVANH
NWVVASSLTTKGAEAYYQEYLMQVIWQTIAMIVAFMVILLGASSIMLRQMRYLNSSMKEIAAQNLSLPVEMNCKDEFGDL
ARELDKTRLQLKSVVENQLSASQELASLTEIMTISMEGTKEAAQEEFAEIDQLATAMSEMNSTVQNVAENARSASIGTEQ
AKIQAKIGQEFVQGTIIKIQALSGDIAASAEVVNQVEERVISISSVVETIRGISEQTNLLALNAAIEAARAGDAGRGFAV
VADEVRNLAQSTQGATVEIQEMITQLQNSANQAVDLMEKSVVEAAEGVELVTNAGTELDSIVNQVNNINEMNFQIASAAE
QQSSVAEEMDQNLTNVRELVEASVVVMTELTETSEEMKKNAEDLESKMKMFKI

Sequences:

>Translated_533_residues
MPVITFKPWERLVTDIKLVPKLVMLMVFSTVLLVSKQLWDANTFYHAVIDVQKESAQSAATANAELINGILNSQSGNQQL
VAEAITAQAKAWTTGNYIYAIDRNSGEVFGHKSIQSLSSLTGSIDGGNSVNQLLRNVSSQQAYSLNDNTRYEFAVKVANH
NWVVASSLTTKGAEAYYQEYLMQVIWQTIAMIVAFMVILLGASSIMLRQMRYLNSSMKEIAAQNLSLPVEMNCKDEFGDL
ARELDKTRLQLKSVVENQLSASQELASLTEIMTISMEGTKEAAQEEFAEIDQLATAMSEMNSTVQNVAENARSASIGTEQ
AKIQAKIGQEFVQGTIIKIQALSGDIAASAEVVNQVEERVISISSVVETIRGISEQTNLLALNAAIEAARAGDAGRGFAV
VADEVRNLAQSTQGATVEIQEMITQLQNSANQAVDLMEKSVVEAAEGVELVTNAGTELDSIVNQVNNINEMNFQIASAAE
QQSSVAEEMDQNLTNVRELVEASVVVMTELTETSEEMKKNAEDLESKMKMFKI
>Mature_532_residues
PVITFKPWERLVTDIKLVPKLVMLMVFSTVLLVSKQLWDANTFYHAVIDVQKESAQSAATANAELINGILNSQSGNQQLV
AEAITAQAKAWTTGNYIYAIDRNSGEVFGHKSIQSLSSLTGSIDGGNSVNQLLRNVSSQQAYSLNDNTRYEFAVKVANHN
WVVASSLTTKGAEAYYQEYLMQVIWQTIAMIVAFMVILLGASSIMLRQMRYLNSSMKEIAAQNLSLPVEMNCKDEFGDLA
RELDKTRLQLKSVVENQLSASQELASLTEIMTISMEGTKEAAQEEFAEIDQLATAMSEMNSTVQNVAENARSASIGTEQA
KIQAKIGQEFVQGTIIKIQALSGDIAASAEVVNQVEERVISISSVVETIRGISEQTNLLALNAAIEAARAGDAGRGFAVV
ADEVRNLAQSTQGATVEIQEMITQLQNSANQAVDLMEKSVVEAAEGVELVTNAGTELDSIVNQVNNINEMNFQIASAAEQ
QSSVAEEMDQNLTNVRELVEASVVVMTELTETSEEMKKNAEDLESKMKMFKI

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=355, Percent_Identity=30.1408450704225, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI2367378, Length=306, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1788195, Length=283, Percent_Identity=30.3886925795053, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1787690, Length=342, Percent_Identity=27.7777777777778, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1789453, Length=349, Percent_Identity=28.6532951289398, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58139; Mature: 58007

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVITFKPWERLVTDIKLVPKLVMLMVFSTVLLVSKQLWDANTFYHAVIDVQKESAQSAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TANAELINGILNSQSGNQQLVAEAITAQAKAWTTGNYIYAIDRNSGEVFGHKSIQSLSSL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCEEEEEECCCCCCCCHHHHHHHHHH
TGSIDGGNSVNQLLRNVSSQQAYSLNDNTRYEFAVKVANHNWVVASSLTTKGAEAYYQEY
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCEEEEECCCCCHHHHHHHHH
LMQVIWQTIAMIVAFMVILLGASSIMLRQMRYLNSSMKEIAAQNLSLPVEMNCKDEFGDL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHH
ARELDKTRLQLKSVVENQLSASQELASLTEIMTISMEGTKEAAQEEFAEIDQLATAMSEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHH
NSTVQNVAENARSASIGTEQAKIQAKIGQEFVQGTIIKIQALSGDIAASAEVVNQVEERV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHH
ISISSVVETIRGISEQTNLLALNAAIEAARAGDAGRGFAVVADEVRNLAQSTQGATVEIQ
HHHHHHHHHHHCCCHHCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEHH
EMITQLQNSANQAVDLMEKSVVEAAEGVELVTNAGTELDSIVNQVNNINEMNFQIASAAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHH
QQSSVAEEMDQNLTNVRELVEASVVVMTELTETSEEMKKNAEDLESKMKMFKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PVITFKPWERLVTDIKLVPKLVMLMVFSTVLLVSKQLWDANTFYHAVIDVQKESAQSAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TANAELINGILNSQSGNQQLVAEAITAQAKAWTTGNYIYAIDRNSGEVFGHKSIQSLSSL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCEEEEEECCCCCCCCHHHHHHHHHH
TGSIDGGNSVNQLLRNVSSQQAYSLNDNTRYEFAVKVANHNWVVASSLTTKGAEAYYQEY
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCEEEEECCCCCHHHHHHHHH
LMQVIWQTIAMIVAFMVILLGASSIMLRQMRYLNSSMKEIAAQNLSLPVEMNCKDEFGDL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHH
ARELDKTRLQLKSVVENQLSASQELASLTEIMTISMEGTKEAAQEEFAEIDQLATAMSEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHH
NSTVQNVAENARSASIGTEQAKIQAKIGQEFVQGTIIKIQALSGDIAASAEVVNQVEERV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHH
ISISSVVETIRGISEQTNLLALNAAIEAARAGDAGRGFAVVADEVRNLAQSTQGATVEIQ
HHHHHHHHHHHCCCHHCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEHH
EMITQLQNSANQAVDLMEKSVVEAAEGVELVTNAGTELDSIVNQVNNINEMNFQIASAAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHH
QQSSVAEEMDQNLTNVRELVEASVVVMTELTETSEEMKKNAEDLESKMKMFKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]