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The map label for this gene is htpG

Identifier: 209694394

GI number: 209694394

Start: 902909

End: 904807

Strand: Direct

Name: htpG

Synonym: VSAL_I0814

Alternate gene names: 209694394

Gene position: 902909-904807 (Clockwise)

Preceding gene: 209694392

Following gene: 209694395

Centisome position: 27.15

GC content: 38.23

Gene sequence:

>1899_bases
ATGAGCGAACAAACTATTAATAACAAAGAAACACGCGGCTTTCAGTCAGAAGTTAAACAACTACTTCATCTAATGATTCA
TTCTTTATATTCAAATAAAGAAATATTTTTACGTGAGCTTATTTCAAACGCATCAGATGCTTCAGATAAATTACGTTTTA
AAGCGTTATCAAACGGCGATTTATACGAAGGCAATGCCGATTTAGGTGTGAAAATTTCGTTTAATGTTGAAGCGAATACT
CTAACCATTTCAGATAATGGTATTGGTATGGGTCGTGAAGATGTTATTGAACATTTGGGCACTATCGCGAAATCTGGTAC
GGCTGATTTCTTCTCAAAATTGTCAGAAGATCAAAGTAAAGATTCTCAACTTATCGGTCAGTTTGGCGTTGGTTTCTACT
CTGCATTTATTGTCGCAGATGCGGTAACGGTTCGTACTCGTGTTGCTGGTGCAGCAAAAGATCAGGCAGTGCAATGGCAC
TCTGAAGGCGAAGGCGATTACACAATAGAAGATGTGACTAAAGAATCTCGTGGTACGGACATTATTCTTCACATGCGTGA
TGAAGGTAAAGAGTTCTTAAGTGAGTGGCGTCTAAAAGAAGTGATTGGTAAATATTCAGATCACATCGGCATCCCGGTTT
CTATTTGGACTGTTGAAAAAGACGAAGAAGGTAAAGAGACTGAAGGTAAGTGGGAGCAAGTAAATAAAGCTCAAGCGCTT
TGGACTCGTAATAAATCAGAAATTGAAGACGCAGAATACCAAGAATTTTATAAGCATGTATCTCATGACTTTGCTGATCC
ACTGACGTGGAGTCACAATAAAGTAGAAGGTAAAAACGACTACACTAGCTTATTGTATATTCCAGCTAAAGCTCCGTTTG
ATATGATGAATCGTGATCATAAAAGTGGTCTTAAACTTTATGTTCAACGCGTGTTTGTTATGGATGATGCTGAGCAGTTC
ATGCCGAGTTACCTACGATTTGTTAAAGGATTAATCGACTCGAATGATTTGGCTCTGAATGTTTCTCGCGAAATACTTCA
AGACAACAAAGTGACTCAATCATTACGTGGTGCGTGTACAAAACGTGTATTAAGTATGCTTGAGAAGATAGCTAAAAAAG
ATAATGATAAATATTTATCTTTTTGGAAAGAGTTTGGGCAAGTATTAAAAGAAGGTTTGGCTGAAGATTTCGCCAATAAA
GATAAAATTGCAGGCCTACTACGTTTTGCTTCTACTAATAAAGACAGCTCAGAACAAGCGATTAGCCTTGCGAGTTATGT
TGAGCGCATGAAAGAAGATCAAGATAAGATTTTCTACCTAACATCTGATAGCTATGCGGCTGCGAAAAATAGCCCACACT
TAGAGCAATTCAAATCAAAAGGCATTGAAGTTGTCTTAATGTATGACCGCATCGATGAGTGGCTAATGAGCTACTTAACT
GAATTTGATGGCAAACAATTCCAATCAATTACCAAAGCTGGTTTGGATTTAAGCAAATTTGAAAACGAAGCGGAAAAAGA
AAAACAAAAAGAAACAACAGAAGAATTTAAGTCAGTAGTTGAACGTACAAAAGCTTACTTAGGTGATCGTGTTAAAGAGG
TTCGTACTACGTTTAAATTAGCGACTACGCCAGCCGTTGTTGTTACCGATGATTTTGAAATGGGTACACAAATGGCGAAA
CTTTTAGAAGCGGCTGGTCAAGCGGCGCCTGAAGTGAAGTACATTTTTGAAATTAACCCTGAGCATGCCCTGATTAAGCA
AATGGCAGATGAAGCGGATGAAGAAGCATTTGGCCGTTGGGTTGAAATGCTACTTGGTCAAGCGATGCTAGCAGAGCGCG
GCTCTTTAGATGATCCATCACAATTTCTAAGTGCAATGAATCAGTTATTATCAAAGTAA

Upstream 100 bases:

>100_bases
AAAAACACCGTTTTTTACATTGGTTTACCTTGAATTGATATTTTATGCCCTTATTACTTTATCAAGTTAATAAACATTAT
CCTTTTTTGGAGTTTTATAG

Downstream 100 bases:

>100_bases
TTGAGATATAACCGTAAACAGTAAAATTAATGAGATCTTGAGTGACAATAGTGCACTAAGGTCTCATTGTTTTTTATTGG
GATTAGTTACATTCTTACTC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 632; Mature: 631

Protein sequence:

>632_residues
MSEQTINNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDASDKLRFKALSNGDLYEGNADLGVKISFNVEANT
LTISDNGIGMGREDVIEHLGTIAKSGTADFFSKLSEDQSKDSQLIGQFGVGFYSAFIVADAVTVRTRVAGAAKDQAVQWH
SEGEGDYTIEDVTKESRGTDIILHMRDEGKEFLSEWRLKEVIGKYSDHIGIPVSIWTVEKDEEGKETEGKWEQVNKAQAL
WTRNKSEIEDAEYQEFYKHVSHDFADPLTWSHNKVEGKNDYTSLLYIPAKAPFDMMNRDHKSGLKLYVQRVFVMDDAEQF
MPSYLRFVKGLIDSNDLALNVSREILQDNKVTQSLRGACTKRVLSMLEKIAKKDNDKYLSFWKEFGQVLKEGLAEDFANK
DKIAGLLRFASTNKDSSEQAISLASYVERMKEDQDKIFYLTSDSYAAAKNSPHLEQFKSKGIEVVLMYDRIDEWLMSYLT
EFDGKQFQSITKAGLDLSKFENEAEKEKQKETTEEFKSVVERTKAYLGDRVKEVRTTFKLATTPAVVVTDDFEMGTQMAK
LLEAAGQAAPEVKYIFEINPEHALIKQMADEADEEAFGRWVEMLLGQAMLAERGSLDDPSQFLSAMNQLLSK

Sequences:

>Translated_632_residues
MSEQTINNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDASDKLRFKALSNGDLYEGNADLGVKISFNVEANT
LTISDNGIGMGREDVIEHLGTIAKSGTADFFSKLSEDQSKDSQLIGQFGVGFYSAFIVADAVTVRTRVAGAAKDQAVQWH
SEGEGDYTIEDVTKESRGTDIILHMRDEGKEFLSEWRLKEVIGKYSDHIGIPVSIWTVEKDEEGKETEGKWEQVNKAQAL
WTRNKSEIEDAEYQEFYKHVSHDFADPLTWSHNKVEGKNDYTSLLYIPAKAPFDMMNRDHKSGLKLYVQRVFVMDDAEQF
MPSYLRFVKGLIDSNDLALNVSREILQDNKVTQSLRGACTKRVLSMLEKIAKKDNDKYLSFWKEFGQVLKEGLAEDFANK
DKIAGLLRFASTNKDSSEQAISLASYVERMKEDQDKIFYLTSDSYAAAKNSPHLEQFKSKGIEVVLMYDRIDEWLMSYLT
EFDGKQFQSITKAGLDLSKFENEAEKEKQKETTEEFKSVVERTKAYLGDRVKEVRTTFKLATTPAVVVTDDFEMGTQMAK
LLEAAGQAAPEVKYIFEINPEHALIKQMADEADEEAFGRWVEMLLGQAMLAERGSLDDPSQFLSAMNQLLSK
>Mature_631_residues
SEQTINNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDASDKLRFKALSNGDLYEGNADLGVKISFNVEANTL
TISDNGIGMGREDVIEHLGTIAKSGTADFFSKLSEDQSKDSQLIGQFGVGFYSAFIVADAVTVRTRVAGAAKDQAVQWHS
EGEGDYTIEDVTKESRGTDIILHMRDEGKEFLSEWRLKEVIGKYSDHIGIPVSIWTVEKDEEGKETEGKWEQVNKAQALW
TRNKSEIEDAEYQEFYKHVSHDFADPLTWSHNKVEGKNDYTSLLYIPAKAPFDMMNRDHKSGLKLYVQRVFVMDDAEQFM
PSYLRFVKGLIDSNDLALNVSREILQDNKVTQSLRGACTKRVLSMLEKIAKKDNDKYLSFWKEFGQVLKEGLAEDFANKD
KIAGLLRFASTNKDSSEQAISLASYVERMKEDQDKIFYLTSDSYAAAKNSPHLEQFKSKGIEVVLMYDRIDEWLMSYLTE
FDGKQFQSITKAGLDLSKFENEAEKEKQKETTEEFKSVVERTKAYLGDRVKEVRTTFKLATTPAVVVTDDFEMGTQMAKL
LEAAGQAAPEVKYIFEINPEHALIKQMADEADEEAFGRWVEMLLGQAMLAERGSLDDPSQFLSAMNQLLSK

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI4507677, Length=631, Percent_Identity=37.5594294770206, Blast_Score=410, Evalue=1e-114,
Organism=Homo sapiens, GI20149594, Length=670, Percent_Identity=36.1194029850746, Blast_Score=396, Evalue=1e-110,
Organism=Homo sapiens, GI155722983, Length=637, Percent_Identity=35.7927786499215, Blast_Score=371, Evalue=1e-102,
Organism=Homo sapiens, GI154146191, Length=399, Percent_Identity=35.8395989974937, Blast_Score=249, Evalue=6e-66,
Organism=Homo sapiens, GI153792590, Length=399, Percent_Identity=35.8395989974937, Blast_Score=248, Evalue=2e-65,
Organism=Escherichia coli, GI1786679, Length=625, Percent_Identity=66.88, Blast_Score=876, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=670, Percent_Identity=37.0149253731343, Blast_Score=435, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI17542208, Length=673, Percent_Identity=36.2555720653789, Blast_Score=394, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI115535205, Length=644, Percent_Identity=33.8509316770186, Blast_Score=323, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI115535167, Length=426, Percent_Identity=37.0892018779343, Blast_Score=269, Evalue=3e-72,
Organism=Saccharomyces cerevisiae, GI6323840, Length=677, Percent_Identity=36.6322008862629, Blast_Score=426, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6325016, Length=412, Percent_Identity=36.8932038834951, Blast_Score=278, Evalue=3e-75,
Organism=Drosophila melanogaster, GI17647529, Length=682, Percent_Identity=36.3636363636364, Blast_Score=437, Evalue=1e-123,
Organism=Drosophila melanogaster, GI21357739, Length=681, Percent_Identity=37.7386196769457, Blast_Score=418, Evalue=1e-117,
Organism=Drosophila melanogaster, GI24586016, Length=650, Percent_Identity=32.9230769230769, Blast_Score=353, Evalue=2e-97,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_ALISL (B6EHJ9)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002262322.1
- GeneID:   6989314
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I0814
- HOGENOM:   HBG631012
- OMA:   DAQELNK
- ProtClustDB:   PRK05218
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71668; Mature: 71537

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQTINNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDASDKLRFKALSNGD
CCCCCCCCHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHEEEEEECCCC
LYEGNADLGVKISFNVEANTLTISDNGIGMGREDVIEHLGTIAKSGTADFFSKLSEDQSK
EECCCCCEEEEEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCH
DSQLIGQFGVGFYSAFIVADAVTVRTRVAGAAKDQAVQWHSEGEGDYTIEDVTKESRGTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEECCCCCCCEEHHHHHHCCCCCE
IILHMRDEGKEFLSEWRLKEVIGKYSDHIGIPVSIWTVEKDEEGKETEGKWEQVNKAQAL
EEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHH
WTRNKSEIEDAEYQEFYKHVSHDFADPLTWSHNKVEGKNDYTSLLYIPAKAPFDMMNRDH
HCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHCCCH
KSGLKLYVQRVFVMDDAEQFMPSYLRFVKGLIDSNDLALNVSREILQDNKVTQSLRGACT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHH
KRVLSMLEKIAKKDNDKYLSFWKEFGQVLKEGLAEDFANKDKIAGLLRFASTNKDSSEQA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHH
ISLASYVERMKEDQDKIFYLTSDSYAAAKNSPHLEQFKSKGIEVVLMYDRIDEWLMSYLT
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHH
EFDGKQFQSITKAGLDLSKFENEAEKEKQKETTEEFKSVVERTKAYLGDRVKEVRTTFKL
HCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
ATTPAVVVTDDFEMGTQMAKLLEAAGQAAPEVKYIFEINPEHALIKQMADEADEEAFGRW
ECCCEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHCCHHHHHHH
VEMLLGQAMLAERGSLDDPSQFLSAMNQLLSK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEQTINNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDASDKLRFKALSNGD
CCCCCCCHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHEEEEEECCCC
LYEGNADLGVKISFNVEANTLTISDNGIGMGREDVIEHLGTIAKSGTADFFSKLSEDQSK
EECCCCCEEEEEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCH
DSQLIGQFGVGFYSAFIVADAVTVRTRVAGAAKDQAVQWHSEGEGDYTIEDVTKESRGTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEECCCCCCCEEHHHHHHCCCCCE
IILHMRDEGKEFLSEWRLKEVIGKYSDHIGIPVSIWTVEKDEEGKETEGKWEQVNKAQAL
EEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHH
WTRNKSEIEDAEYQEFYKHVSHDFADPLTWSHNKVEGKNDYTSLLYIPAKAPFDMMNRDH
HCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHCCCH
KSGLKLYVQRVFVMDDAEQFMPSYLRFVKGLIDSNDLALNVSREILQDNKVTQSLRGACT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHH
KRVLSMLEKIAKKDNDKYLSFWKEFGQVLKEGLAEDFANKDKIAGLLRFASTNKDSSEQA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHH
ISLASYVERMKEDQDKIFYLTSDSYAAAKNSPHLEQFKSKGIEVVLMYDRIDEWLMSYLT
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHH
EFDGKQFQSITKAGLDLSKFENEAEKEKQKETTEEFKSVVERTKAYLGDRVKEVRTTFKL
HCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
ATTPAVVVTDDFEMGTQMAKLLEAAGQAAPEVKYIFEINPEHALIKQMADEADEEAFGRW
ECCCEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHCCHHHHHHH
VEMLLGQAMLAERGSLDDPSQFLSAMNQLLSK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA