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The map label for this gene is trpB [H]

Identifier: 209551525

GI number: 209551525

Start: 4102276

End: 4103496

Strand: Direct

Name: trpB [H]

Synonym: Rleg2_3954

Alternate gene names: 209551525

Gene position: 4102276-4103496 (Clockwise)

Preceding gene: 209551524

Following gene: 209551526

Centisome position: 90.4

GC content: 61.75

Gene sequence:

>1221_bases
GTGAACGAAACGCCTAAACCGAATTCCTTCCGTTCCGGGCCTGATGAAGACGGCCGCTTCGGCATCTATGGCGGTCGTTT
CGTTGCCGAAACGTTGATGCCTTTGATTCTCGATCTGCAGGACGAGTGGAACAAGGCGAAGAACGATCCGGCATTCCAGG
CCGAATTGAAGCATCTCGGCGCCCATTATATCGGCCGCCCGAGCCCGCTCTATTTCGCCGAGCGGCTGACGGCCGAACTC
GGCGGCGCGAAGATCTATTTCAAGCGCGAGGAGCTGAACCACACTGGCTCGCACAAGATCAACAACTGCATCGGCCAGAT
CCTGCTCGCCAAGCGCATGGGCAAGACCCGGATCATCGCCGAAACCGGCGCCGGCCAGCATGGTGTTGCCTCGGCTACCG
TTGCCGCCCGCTTCGGCCTTCCCTGCGTCGTCTATATGGGCGCCACCGACGTCGAGCGTCAGGCGCCGAACGTTTTCCGC
ATGAAGCTGCTCGGCGCGGAAGTGAAGCCGGTGACTGCCGGCAGCGGCACGCTGAAGGACGCGATGAACGAGGCGCTTCG
CGACTGGGTCACCAATGTCGAAGATACCTACTACCTGATCGGAACGGCGGCCGGTCCGCATCCCTATCCGGAGATGGTCC
GCGATTTCCAGTCGGTGATCGGCACCGAAGCGAAAGAGCAGATGCTGGCAGCCGAAGGCCGCCTGCCGGATCTCGTCATC
GCTGCCGTCGGCGGCGGTTCGAACGCGATCGGCATTTTTCATCCTTTCCTCGATGATCCCACCGTGAAGATTGTCGGCGT
CGAAGCAGGCGGCAAGGGCCTGCAGGGCGACGAGCATTGCGCCTCGATCACCGCCGGTTCGCCGGGTGTGCTGCACGGCA
ACCGCACCTATCTGCTGCAGGATGGCGATGGCCAGATCAAGGAAGGCCATTCGATTTCGGCCGGTCTCGATTATCCCGGC
ATCGGCCCCGAGCATTCCTGGCTGAACGATACCGGCCGCGTCGACTATGTTCCGATCATGGATCACGAAGCGCTCGAGGC
GTTCCAGACGCTGACCCGCCTCGAAGGCATCATCCCGGCGCTCGAGCCCTCGCACGCGATTGCCGAGGTGATCAAGCGCG
CACCGAAGATGGGCAAGGACGAGATCATCCTGATGAACCTCTCCGGCCGCGGCGACAAGGATATCTTCACCGTCGGCAAG
ATTCTGGGAATGGGACTGTAA

Upstream 100 bases:

>100_bases
TCGAGACTGCGCCTGGCGTGAAGAGCGTCGCAATGATCGATGAATTTTTCGATGCGGTCGAAGAGGCGGATGCGCCTGTC
ATGGCCTCAGGGAGTTGAGA

Downstream 100 bases:

>100_bases
GACATGACCGCACGCATGGACAAACGCTTTGCCGAGCTGAAGGCCGAGGGCCGTCCGGCGCTTGTGACCTATTTCATGGG
CGGCGATCCTGATTACGATA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MNETPKPNSFRSGPDEDGRFGIYGGRFVAETLMPLILDLQDEWNKAKNDPAFQAELKHLGAHYIGRPSPLYFAERLTAEL
GGAKIYFKREELNHTGSHKINNCIGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCVVYMGATDVERQAPNVFR
MKLLGAEVKPVTAGSGTLKDAMNEALRDWVTNVEDTYYLIGTAAGPHPYPEMVRDFQSVIGTEAKEQMLAAEGRLPDLVI
AAVGGGSNAIGIFHPFLDDPTVKIVGVEAGGKGLQGDEHCASITAGSPGVLHGNRTYLLQDGDGQIKEGHSISAGLDYPG
IGPEHSWLNDTGRVDYVPIMDHEALEAFQTLTRLEGIIPALEPSHAIAEVIKRAPKMGKDEIILMNLSGRGDKDIFTVGK
ILGMGL

Sequences:

>Translated_406_residues
MNETPKPNSFRSGPDEDGRFGIYGGRFVAETLMPLILDLQDEWNKAKNDPAFQAELKHLGAHYIGRPSPLYFAERLTAEL
GGAKIYFKREELNHTGSHKINNCIGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCVVYMGATDVERQAPNVFR
MKLLGAEVKPVTAGSGTLKDAMNEALRDWVTNVEDTYYLIGTAAGPHPYPEMVRDFQSVIGTEAKEQMLAAEGRLPDLVI
AAVGGGSNAIGIFHPFLDDPTVKIVGVEAGGKGLQGDEHCASITAGSPGVLHGNRTYLLQDGDGQIKEGHSISAGLDYPG
IGPEHSWLNDTGRVDYVPIMDHEALEAFQTLTRLEGIIPALEPSHAIAEVIKRAPKMGKDEIILMNLSGRGDKDIFTVGK
ILGMGL
>Mature_406_residues
MNETPKPNSFRSGPDEDGRFGIYGGRFVAETLMPLILDLQDEWNKAKNDPAFQAELKHLGAHYIGRPSPLYFAERLTAEL
GGAKIYFKREELNHTGSHKINNCIGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCVVYMGATDVERQAPNVFR
MKLLGAEVKPVTAGSGTLKDAMNEALRDWVTNVEDTYYLIGTAAGPHPYPEMVRDFQSVIGTEAKEQMLAAEGRLPDLVI
AAVGGGSNAIGIFHPFLDDPTVKIVGVEAGGKGLQGDEHCASITAGSPGVLHGNRTYLLQDGDGQIKEGHSISAGLDYPG
IGPEHSWLNDTGRVDYVPIMDHEALEAFQTLTRLEGIIPALEPSHAIAEVIKRAPKMGKDEIILMNLSGRGDKDIFTVGK
ILGMGL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=384, Percent_Identity=56.7708333333333, Blast_Score=438, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6321412, Length=385, Percent_Identity=56.3636363636364, Blast_Score=451, Evalue=1e-128,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43690; Mature: 43690

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNETPKPNSFRSGPDEDGRFGIYGGRFVAETLMPLILDLQDEWNKAKNDPAFQAELKHLG
CCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AHYIGRPSPLYFAERLTAELGGAKIYFKREELNHTGSHKINNCIGQILLAKRMGKTRIIA
HHHCCCCCHHHHHHHHHHHCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEE
ETGAGQHGVASATVAARFGLPCVVYMGATDVERQAPNVFRMKLLGAEVKPVTAGSGTLKD
ECCCCCCCCHHHHHHHHCCCCEEEEECCCCHHHHCCCCEEHHHHCCCCCEEECCCCHHHH
AMNEALRDWVTNVEDTYYLIGTAAGPHPYPEMVRDFQSVIGTEAKEQMLAAEGRLPDLVI
HHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEE
AAVGGGSNAIGIFHPFLDDPTVKIVGVEAGGKGLQGDEHCASITAGSPGVLHGNRTYLLQ
EEECCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHEECCCCCCEEECCEEEEEE
DGDGQIKEGHSISAGLDYPGIGPEHSWLNDTGRVDYVPIMDHEALEAFQTLTRLEGIIPA
CCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCC
LEPSHAIAEVIKRAPKMGKDEIILMNLSGRGDKDIFTVGKILGMGL
CCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNETPKPNSFRSGPDEDGRFGIYGGRFVAETLMPLILDLQDEWNKAKNDPAFQAELKHLG
CCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AHYIGRPSPLYFAERLTAELGGAKIYFKREELNHTGSHKINNCIGQILLAKRMGKTRIIA
HHHCCCCCHHHHHHHHHHHCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEE
ETGAGQHGVASATVAARFGLPCVVYMGATDVERQAPNVFRMKLLGAEVKPVTAGSGTLKD
ECCCCCCCCHHHHHHHHCCCCEEEEECCCCHHHHCCCCEEHHHHCCCCCEEECCCCHHHH
AMNEALRDWVTNVEDTYYLIGTAAGPHPYPEMVRDFQSVIGTEAKEQMLAAEGRLPDLVI
HHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEE
AAVGGGSNAIGIFHPFLDDPTVKIVGVEAGGKGLQGDEHCASITAGSPGVLHGNRTYLLQ
EEECCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHEECCCCCCEEECCEEEEEE
DGDGQIKEGHSISAGLDYPGIGPEHSWLNDTGRVDYVPIMDHEALEAFQTLTRLEGIIPA
CCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCC
LEPSHAIAEVIKRAPKMGKDEIILMNLSGRGDKDIFTVGKILGMGL
CCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA