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The map label for this gene is hpuB [H]

Identifier: 209550392

GI number: 209550392

Start: 2858665

End: 2860923

Strand: Reverse

Name: hpuB [H]

Synonym: Rleg2_2813

Alternate gene names: 209550392

Gene position: 2860923-2858665 (Counterclockwise)

Preceding gene: 209550394

Following gene: 209550391

Centisome position: 63.04

GC content: 59.19

Gene sequence:

>2259_bases
ATGATCGTCCGGTATTGGCGCTCGATTCTATTGGTCTGCACGGCAGCCGCAGTTGTTCTTCCTGTTTCACAGTCTTTCGC
GCAAAGCGCTGCGGCAACCACGCCGCAAGCGACGACGGACGACAGCACCGTCCTGCAGAAGATCGTCGTCAAGGGCAAAC
GCGTGGCGCCGGGCAGCGTCGCCGATACGCCGCTTGCGACGGAAATCACCCAGAAGCAACTGGAAGAGAAGCAGGTCACC
AATTACGACGATATCGGCCGTAGCGTCGATGCGGGCGTGAACTATTCGCGTGGCGATGCAGGCTTCAACCTGCGCGGCCT
TTCCGGTGCTCGCATCCTGACCACCATCGACGGAATTCCGATCCCTTATATTTCGAACAGCTCGCGCCAGGGCGCTTTTG
CGCCTGCCAACGCCAATGGCGGCGGCGATACCTTCGATTTCGATTCGCTATCTTCACTCGATATCGTGCGCGGCGCGGAT
TCGAGCAAGGGCGGTTCAGGCATGCTCGGCGGCGCCATCGTTCTCAATACGTTGAAGCCTGAGGATCTCATTCCTGAAGG
CCGCGACTGGGGTGCAATCGTCAAGTCAACCTATGACAGCGAAGACAGGAGCCTTTCCGGCTCAGCCGCCGCTGCCAAGA
AGATCGGCGGCACCTCGATCCTGTTCCAGGGCGGCTACCGCAAAGGCCATGAACGCGACAATATGGGCGACAACGACAGC
TACGGTGCTCTTCGCACCGAGGCGAATCCGGCTGACTTCGATCAGAACAACCTGCTCTTCAAACTGCGTCAGGAGTTGGA
AGGCGGCCATCGCATCGGCTTGACAGCGGAACGGTTCCGCCGGGATCTAAAAACCGACCTGCGCCAACTTCAGGGGGGCA
CCAGCCCTCGCAACTTCATGATCGACAATTATGACGGTCGCGAACTGCGCGACCGCGATCGCGTGTCGCTCGATTATGAT
TATGAAGCGCAGTCCTCCGATGCCTTCTTCAGCAGTGCTCGCGCCACGCTTTATTGGCTGGATCTGAAGAAGGAAGCCGG
CAGCAGGGGCCGCACGACCGCCAATGTGGCCTATGGCCGTAACAACGAGATCGAAAACGAAACCTGGGGCTTCAGCGGCA
CCGCGACGAAGGATTTCGAATATTCCGGTCTCAACCACTCCATGCGCGTCGGTCTCGATGTCGGCGTCTCCAGCTGGAGC
CAGTATAGCTGGGCTCTTTGCCCCACATCGACAACATGCCCGGCACTGAACAACCAGGCGGAAGTACCTGATGTCGACAG
CCAAAACCTTGGTCTTGTTGTCGAAGACAAGATCGAAATCGGCAACACCGGCTTCACGCTGACACCCGGTTTCCGCTTCG
ACTGGTTCAACTACAATCCCTCGACCGGCGGCGATTTTGCCAATAATACCGGCCTTACTCGTTTCGGCGATCTTCGCAAC
CGGACGGAAGCCGCCCTGTCGCCGAAGATCCTTGCAACATACGACCTGACGCCTGACGTGGAGCTCTACATGCAATTGGC
GGTCGGCTTCCGCGCGCCAACCGTCGACGAACTCTACAGCCGCTTCTACAACCCTACTAGCCGCTACGCCCAGCTGGGCA
ATCCTGATCTGGAACCGGAAATCGGTCGAGGCATCGAAGTCGGCGCCACCTTTGACACGGGCGATGTTACCGGAAGGGTC
GCGCTTTTCCACACCCGCTACCAGAACTTCATCGAGACGGTGACAACCACGGACGCGACAGGCTTCACGGAGTTCAATTA
CACAAACGTAGCAGCGGCGACGATCTCAGGTATCGAAGCCAGCGCCGCCAAGACCTTCAACAACGGCATCAATCTGCATG
CGTCGCTTGCCTATGCCTATGGCAGGAATGAAGAAACCACGCAGCGCCTGCGCTCGGTGGCGCCGTTCAAGGCAATTGTC
GGCGGCGGCTGGAGCAACGAAACCTTCGGCTTCGATCTTTCCTCGACGCTTTCGGCCGGCATGCTGACCGATCATCTCAA
TACGCCCGTCACCAACACCGCCGACACGACCTTCGATGCGCCCGGTTATGCGATCGTGGACCTGACCGGTTGGTGGACGC
CGGAACGGCTGCCGGGCCTGCGCATCCAGGGGGGTGTCTACAACATCTTTGATCAGGAGCACTATAACGCACTCGCCGTG
CGCGAGGTCAATCTGAGCTCGGCGACGGCATCCCAGCCTCGGGAGTGGTATTCCGAGCCCGGCCGTACCTTCAAGGTCTC
GCTCACCAAGACGTTCTGA

Upstream 100 bases:

>100_bases
AATTCTGCATCGCCTTCATCCGCAAAAGCCCAGCCAGCCCCTCGAGCGTTCGACGCGCCACGACCAGCCAGCCCGGTAAT
CATCATTTAGAGGGTAGGTT

Downstream 100 bases:

>100_bases
TTACAAGTCTTCAAGGCTGGGGTGGGGCGGCTTTCGGGCCGCCCCTTTCATTCGCGCAATCGCCTCTTGCGCGGCGGCTG
ATCTCAGGCTAACAATTTTT

Product: TonB-dependent hemoglobin/transferrin/lactoferrin family receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 752; Mature: 752

Protein sequence:

>752_residues
MIVRYWRSILLVCTAAAVVLPVSQSFAQSAAATTPQATTDDSTVLQKIVVKGKRVAPGSVADTPLATEITQKQLEEKQVT
NYDDIGRSVDAGVNYSRGDAGFNLRGLSGARILTTIDGIPIPYISNSSRQGAFAPANANGGGDTFDFDSLSSLDIVRGAD
SSKGGSGMLGGAIVLNTLKPEDLIPEGRDWGAIVKSTYDSEDRSLSGSAAAAKKIGGTSILFQGGYRKGHERDNMGDNDS
YGALRTEANPADFDQNNLLFKLRQELEGGHRIGLTAERFRRDLKTDLRQLQGGTSPRNFMIDNYDGRELRDRDRVSLDYD
YEAQSSDAFFSSARATLYWLDLKKEAGSRGRTTANVAYGRNNEIENETWGFSGTATKDFEYSGLNHSMRVGLDVGVSSWS
QYSWALCPTSTTCPALNNQAEVPDVDSQNLGLVVEDKIEIGNTGFTLTPGFRFDWFNYNPSTGGDFANNTGLTRFGDLRN
RTEAALSPKILATYDLTPDVELYMQLAVGFRAPTVDELYSRFYNPTSRYAQLGNPDLEPEIGRGIEVGATFDTGDVTGRV
ALFHTRYQNFIETVTTTDATGFTEFNYTNVAAATISGIEASAAKTFNNGINLHASLAYAYGRNEETTQRLRSVAPFKAIV
GGGWSNETFGFDLSSTLSAGMLTDHLNTPVTNTADTTFDAPGYAIVDLTGWWTPERLPGLRIQGGVYNIFDQEHYNALAV
REVNLSSATASQPREWYSEPGRTFKVSLTKTF

Sequences:

>Translated_752_residues
MIVRYWRSILLVCTAAAVVLPVSQSFAQSAAATTPQATTDDSTVLQKIVVKGKRVAPGSVADTPLATEITQKQLEEKQVT
NYDDIGRSVDAGVNYSRGDAGFNLRGLSGARILTTIDGIPIPYISNSSRQGAFAPANANGGGDTFDFDSLSSLDIVRGAD
SSKGGSGMLGGAIVLNTLKPEDLIPEGRDWGAIVKSTYDSEDRSLSGSAAAAKKIGGTSILFQGGYRKGHERDNMGDNDS
YGALRTEANPADFDQNNLLFKLRQELEGGHRIGLTAERFRRDLKTDLRQLQGGTSPRNFMIDNYDGRELRDRDRVSLDYD
YEAQSSDAFFSSARATLYWLDLKKEAGSRGRTTANVAYGRNNEIENETWGFSGTATKDFEYSGLNHSMRVGLDVGVSSWS
QYSWALCPTSTTCPALNNQAEVPDVDSQNLGLVVEDKIEIGNTGFTLTPGFRFDWFNYNPSTGGDFANNTGLTRFGDLRN
RTEAALSPKILATYDLTPDVELYMQLAVGFRAPTVDELYSRFYNPTSRYAQLGNPDLEPEIGRGIEVGATFDTGDVTGRV
ALFHTRYQNFIETVTTTDATGFTEFNYTNVAAATISGIEASAAKTFNNGINLHASLAYAYGRNEETTQRLRSVAPFKAIV
GGGWSNETFGFDLSSTLSAGMLTDHLNTPVTNTADTTFDAPGYAIVDLTGWWTPERLPGLRIQGGVYNIFDQEHYNALAV
REVNLSSATASQPREWYSEPGRTFKVSLTKTF
>Mature_752_residues
MIVRYWRSILLVCTAAAVVLPVSQSFAQSAAATTPQATTDDSTVLQKIVVKGKRVAPGSVADTPLATEITQKQLEEKQVT
NYDDIGRSVDAGVNYSRGDAGFNLRGLSGARILTTIDGIPIPYISNSSRQGAFAPANANGGGDTFDFDSLSSLDIVRGAD
SSKGGSGMLGGAIVLNTLKPEDLIPEGRDWGAIVKSTYDSEDRSLSGSAAAAKKIGGTSILFQGGYRKGHERDNMGDNDS
YGALRTEANPADFDQNNLLFKLRQELEGGHRIGLTAERFRRDLKTDLRQLQGGTSPRNFMIDNYDGRELRDRDRVSLDYD
YEAQSSDAFFSSARATLYWLDLKKEAGSRGRTTANVAYGRNNEIENETWGFSGTATKDFEYSGLNHSMRVGLDVGVSSWS
QYSWALCPTSTTCPALNNQAEVPDVDSQNLGLVVEDKIEIGNTGFTLTPGFRFDWFNYNPSTGGDFANNTGLTRFGDLRN
RTEAALSPKILATYDLTPDVELYMQLAVGFRAPTVDELYSRFYNPTSRYAQLGNPDLEPEIGRGIEVGATFDTGDVTGRV
ALFHTRYQNFIETVTTTDATGFTEFNYTNVAAATISGIEASAAKTFNNGINLHASLAYAYGRNEETTQRLRSVAPFKAIV
GGGWSNETFGFDLSSTLSAGMLTDHLNTPVTNTADTTFDAPGYAIVDLTGWWTPERLPGLRIQGGVYNIFDQEHYNALAV
REVNLSSATASQPREWYSEPGRTFKVSLTKTF

Specific function: Acts as a receptor for hemoglobin or the hemoglobin/haptoglobin complex and is required for heme uptake [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1790743, Length=669, Percent_Identity=22.4215246636771, Blast_Score=73, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010949
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 81893; Mature: 81893

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVRYWRSILLVCTAAAVVLPVSQSFAQSAAATTPQATTDDSTVLQKIVVKGKRVAPGSV
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
ADTPLATEITQKQLEEKQVTNYDDIGRSVDAGVNYSRGDAGFNLRGLSGARILTTIDGIP
CCCCHHHHHHHHHHHHHHCCCHHHHCCCHHCCCCCCCCCCCEEEECCCCCEEEEEECCCC
IPYISNSSRQGAFAPANANGGGDTFDFDSLSSLDIVRGADSSKGGSGMLGGAIVLNTLKP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCC
EDLIPEGRDWGAIVKSTYDSEDRSLSGSAAAAKKIGGTSILFQGGYRKGHERDNMGDNDS
HHCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCC
YGALRTEANPADFDQNNLLFKLRQELEGGHRIGLTAERFRRDLKTDLRQLQGGTSPRNFM
CCEEECCCCCCCCCCCCHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCEE
IDNYDGRELRDRDRVSLDYDYEAQSSDAFFSSARATLYWLDLKKEAGSRGRTTANVAYGR
EECCCCCCCCCCCCEEEEECCCCCCCCHHHHCCCEEEEEEEEEHHCCCCCCEEEEEEECC
NNEIENETWGFSGTATKDFEYSGLNHSMRVGLDVGVSSWSQYSWALCPTSTTCPALNNQA
CCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCC
EVPDVDSQNLGLVVEDKIEIGNTGFTLTPGFRFDWFNYNPSTGGDFANNTGLTRFGDLRN
CCCCCCCCCCCEEEECCEEECCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHC
RTEAALSPKILATYDLTPDVELYMQLAVGFRAPTVDELYSRFYNPTSRYAQLGNPDLEPE
HHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHCCCCCCCCC
IGRGIEVGATFDTGDVTGRVALFHTRYQNFIETVTTTDATGFTEFNYTNVAAATISGIEA
CCCCEEECEEECCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCEECCCCCEEEHHHCCCHH
SAAKTFNNGINLHASLAYAYGRNEETTQRLRSVAPFKAIVGGGWSNETFGFDLSSTLSAG
HHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHH
MLTDHLNTPVTNTADTTFDAPGYAIVDLTGWWTPERLPGLRIQGGVYNIFDQEHYNALAV
HHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCEEEECCCCCCCEEEE
REVNLSSATASQPREWYSEPGRTFKVSLTKTF
EEECCCCCCCCCCHHHHCCCCCEEEEEEEECC
>Mature Secondary Structure
MIVRYWRSILLVCTAAAVVLPVSQSFAQSAAATTPQATTDDSTVLQKIVVKGKRVAPGSV
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
ADTPLATEITQKQLEEKQVTNYDDIGRSVDAGVNYSRGDAGFNLRGLSGARILTTIDGIP
CCCCHHHHHHHHHHHHHHCCCHHHHCCCHHCCCCCCCCCCCEEEECCCCCEEEEEECCCC
IPYISNSSRQGAFAPANANGGGDTFDFDSLSSLDIVRGADSSKGGSGMLGGAIVLNTLKP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCC
EDLIPEGRDWGAIVKSTYDSEDRSLSGSAAAAKKIGGTSILFQGGYRKGHERDNMGDNDS
HHCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCC
YGALRTEANPADFDQNNLLFKLRQELEGGHRIGLTAERFRRDLKTDLRQLQGGTSPRNFM
CCEEECCCCCCCCCCCCHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCEE
IDNYDGRELRDRDRVSLDYDYEAQSSDAFFSSARATLYWLDLKKEAGSRGRTTANVAYGR
EECCCCCCCCCCCCEEEEECCCCCCCCHHHHCCCEEEEEEEEEHHCCCCCCEEEEEEECC
NNEIENETWGFSGTATKDFEYSGLNHSMRVGLDVGVSSWSQYSWALCPTSTTCPALNNQA
CCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCC
EVPDVDSQNLGLVVEDKIEIGNTGFTLTPGFRFDWFNYNPSTGGDFANNTGLTRFGDLRN
CCCCCCCCCCCEEEECCEEECCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHC
RTEAALSPKILATYDLTPDVELYMQLAVGFRAPTVDELYSRFYNPTSRYAQLGNPDLEPE
HHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHCCCCCCCCC
IGRGIEVGATFDTGDVTGRVALFHTRYQNFIETVTTTDATGFTEFNYTNVAAATISGIEA
CCCCEEECEEECCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCEECCCCCEEEHHHCCCHH
SAAKTFNNGINLHASLAYAYGRNEETTQRLRSVAPFKAIVGGGWSNETFGFDLSSTLSAG
HHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHH
MLTDHLNTPVTNTADTTFDAPGYAIVDLTGWWTPERLPGLRIQGGVYNIFDQEHYNALAV
HHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCEEEECCCCCCCEEEE
REVNLSSATASQPREWYSEPGRTFKVSLTKTF
EEECCCCCCCCCCHHHHCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]