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The map label for this gene is fbcH [H]

Identifier: 209550355

GI number: 209550355

Start: 2819603

End: 2820487

Strand: Reverse

Name: fbcH [H]

Synonym: Rleg2_2776

Alternate gene names: 209550355

Gene position: 2820487-2819603 (Counterclockwise)

Preceding gene: 209550356

Following gene: 209550354

Centisome position: 62.15

GC content: 61.81

Gene sequence:

>885_bases
ATGAAAACGCTTGTTGCAAGCATTCTTTCGCTCGCAGTCGCTGCCGTTCTCGGCAGCGCAGCCTTGGCCCAGGAAGCGAC
GCCCGCCAATGGAGCAGCACCCGCCCATCACGAGGAAGGTGCGACGCCGCACTATCCGCTGAAGGAGCCGAAGGAGGAGG
AATGGACTTTCGCCGGTCCGTTCGGCCATTACGACAAGGCTCAGCTTCAGCGCGGCCTCAAGGTCTACACCGAAGTCTGT
TCCGCCTGCCATTCGATGAACCTCGTGCCTTTCCGCATGCTCGACGAGCTCGGCTATAACGAGGCGCAGGTGAAGGCTTT
CGCTGCGAATTACGAAGTCCAGGACGGGCCGAATGCGGCCGGCGAGATGTTTACCCGCAAGGCGGTCCCTTCCGACCACT
TCCCGGCGCCTTTCGCCAATGCGGAGGCGGCTGCCGCTTCCAACAACGGCGCGGCTCCGCCTGACTTTTCGCTGATCGCC
AAGGCCCGCGAAGTCGAGCGCGGCTTCCCGCAATTCGTCTTCGACATCTTCACGCAGTATCAGGAAAATGGCCCGGATTA
TATCCACGCGCTGCTGACCGGCTATGAAGAACCACCGGCCGGCTTCCAGGTGCCGCAGGGCGGACATTACAACCCGTATT
TCCATGCCGCCGCCGTCCTCGCCATGCCGAAGCCGCTCTCGGACGGCCAGGTGACCTATGATGACGGCGCGCCGCAGACC
GTCGACCAGTATTCCAAGGACGTTTCCTCCTTCCTGATGTGGGCCGCCGAGCCGCATCTCGAGGAGCGCAAGCGCACCGG
TTTCATGGTCATGGTCTTCCTGGCGATCTTCACGGTGCTGATCTACCTGACGAAGCGCTCGGTCTACGCCAACAAGGAGC
ATTGA

Upstream 100 bases:

>100_bases
CCGAACTCGATCACCGAAGCGGTGCTCGAAAAGCGCAACAAGACAGTTGCTGCCAATGCAGCGGCCAATGCGTAAGCGAG
CGGCGGAAGGAAACAGAAAT

Downstream 100 bases:

>100_bases
GCGCTCCTTGCCTGAATTTTGAAAGGCGGCTTGAGGGCCGCCTTTTTTGTTGGTTCCGCCCCTGGCAATTGATAGGGTGC
CGCCATCCTGTTCCAAACTA

Product: cytochrome C1

Products: Q; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKTLVASILSLAVAAVLGSAALAQEATPANGAAPAHHEEGATPHYPLKEPKEEEWTFAGPFGHYDKAQLQRGLKVYTEVC
SACHSMNLVPFRMLDELGYNEAQVKAFAANYEVQDGPNAAGEMFTRKAVPSDHFPAPFANAEAAAASNNGAAPPDFSLIA
KAREVERGFPQFVFDIFTQYQENGPDYIHALLTGYEEPPAGFQVPQGGHYNPYFHAAAVLAMPKPLSDGQVTYDDGAPQT
VDQYSKDVSSFLMWAAEPHLEERKRTGFMVMVFLAIFTVLIYLTKRSVYANKEH

Sequences:

>Translated_294_residues
MKTLVASILSLAVAAVLGSAALAQEATPANGAAPAHHEEGATPHYPLKEPKEEEWTFAGPFGHYDKAQLQRGLKVYTEVC
SACHSMNLVPFRMLDELGYNEAQVKAFAANYEVQDGPNAAGEMFTRKAVPSDHFPAPFANAEAAAASNNGAAPPDFSLIA
KAREVERGFPQFVFDIFTQYQENGPDYIHALLTGYEEPPAGFQVPQGGHYNPYFHAAAVLAMPKPLSDGQVTYDDGAPQT
VDQYSKDVSSFLMWAAEPHLEERKRTGFMVMVFLAIFTVLIYLTKRSVYANKEH
>Mature_294_residues
MKTLVASILSLAVAAVLGSAALAQEATPANGAAPAHHEEGATPHYPLKEPKEEEWTFAGPFGHYDKAQLQRGLKVYTEVC
SACHSMNLVPFRMLDELGYNEAQVKAFAANYEVQDGPNAAGEMFTRKAVPSDHFPAPFANAEAAAASNNGAAPPDFSLIA
KAREVERGFPQFVFDIFTQYQENGPDYIHALLTGYEEPPAGFQVPQGGHYNPYFHAAAVLAMPKPLSDGQVTYDDGAPQT
VDQYSKDVSSFLMWAAEPHLEERKRTGFMVMVFLAIFTVLIYLTKRSVYANKEH

Specific function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c [H]

COG id: COG2857

COG function: function code C; Cytochrome c1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI21359867, Length=241, Percent_Identity=41.0788381742739, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17506225, Length=236, Percent_Identity=38.5593220338983, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324639, Length=237, Percent_Identity=40.9282700421941, Blast_Score=186, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24658292, Length=237, Percent_Identity=39.662447257384, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI21358225, Length=238, Percent_Identity=38.655462184874, Blast_Score=164, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016175
- InterPro:   IPR005798
- InterPro:   IPR005797
- InterPro:   IPR002326
- InterPro:   IPR021157
- InterPro:   IPR009056
- InterPro:   IPR016174 [H]

Pfam domain/function: PF00032 Cytochrom_B_C; PF00033 Cytochrom_B_N; PF02167 Cytochrom_C1 [H]

EC number: 1.10.2.2

Molecular weight: Translated: 32147; Mature: 32147

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLVASILSLAVAAVLGSAALAQEATPANGAAPAHHEEGATPHYPLKEPKEEEWTFAGP
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECC
FGHYDKAQLQRGLKVYTEVCSACHSMNLVPFRMLDELGYNEAQVKAFAANYEVQDGPNAA
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHH
GEMFTRKAVPSDHFPAPFANAEAAAASNNGAAPPDFSLIAKAREVERGFPQFVFDIFTQY
HHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
QENGPDYIHALLTGYEEPPAGFQVPQGGHYNPYFHAAAVLAMPKPLSDGQVTYDDGAPQT
HHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCHH
VDQYSKDVSSFLMWAAEPHLEERKRTGFMVMVFLAIFTVLIYLTKRSVYANKEH
HHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKTLVASILSLAVAAVLGSAALAQEATPANGAAPAHHEEGATPHYPLKEPKEEEWTFAGP
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECC
FGHYDKAQLQRGLKVYTEVCSACHSMNLVPFRMLDELGYNEAQVKAFAANYEVQDGPNAA
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHH
GEMFTRKAVPSDHFPAPFANAEAAAASNNGAAPPDFSLIAKAREVERGFPQFVFDIFTQY
HHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
QENGPDYIHALLTGYEEPPAGFQVPQGGHYNPYFHAAAVLAMPKPLSDGQVTYDDGAPQT
HHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCHH
VDQYSKDVSSFLMWAAEPHLEERKRTGFMVMVFLAIFTVLIYLTKRSVYANKEH
HHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: QH2; ferricytochrome c

Specific reaction: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2541921; 12597275 [H]